Clinical trials
Anaplastic Thyroid Cancer clinical trials
Below are recruiting anaplastic thyroid cancer clinical trials, each written for real people, not researchers. We’re tracking 31 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06007924RecruitingPhase 2
Study of two drugs for advanced thyroid cancer
This trial tests two oral medications, avutometinib and defactinib, for people with advanced thyroid cancer that has specific genetic changes. The goal is to see if these drugs can shrink tumors or slow their growth.
Basking Ridge, New JerseyAges 18 years+ - NCT06079333RecruitingPhase 2
Targeted therapy before and after surgery for BRAF-mutant anaplastic thyroid cancer
This trial tests whether giving a targeted therapy pill (which attacks cancer cells with a BRAF mutation) before and after surgery can help treat anaplastic thyroid cancer that hasn't spread to other organs. It's for people whose cancer has a specific gene change (BRAF V600E or V600K) and who are healthy enough for surgery.
Leiden, South HollandAges 18 years+ - NCT07874321RecruitingPhase 2
Study of MRG003 for advanced thyroid cancer that has progressed on current therapy
This trial tests an investigational drug called MRG003 added to your current treatment for advanced thyroid cancer that has stopped responding. It may help people with specific types of thyroid cancer and certain tumor markers.
Guangzhou, GuangdongAges 18–80 - NCT05837260Recruiting
Tracking tumor DNA changes in advanced thyroid cancers
This study looks at a small blood test (called ctDNA) and tumor tissue to understand how advanced thyroid cancers change over time. It may help doctors better monitor cancer growth and guide treatment choices.
LondonAges 18 years+ - NCT07777536RecruitingPhase 2
Radiation for anaplastic and poorly differentiated thyroid cancer
This study is comparing two different ways of giving radiation therapy for anaplastic and poorly differentiated thyroid cancer. The goal is to see which method is more effective in treating the cancer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06149637Recruiting
Lateral neck lymph node surgery for thyroid cancer
This trial tests a surgical procedure to remove cancer-affected lymph nodes on the side of the neck in patients with differentiated thyroid cancer. It aims to improve outcomes for those with confirmed or suspected spread to these nodes.
Medellín, AntioquiaAges 18–99 - NCT07419932Recruiting
Pre-surgery treatment for advanced thyroid cancer
This study tests whether giving treatment before surgery (neoadjuvant therapy) helps people with locally advanced thyroid cancer. It aims to shrink the tumor so surgery can be more successful.
Fuzhou, FujianAges 14–80 - NCT07092514RecruitingPhase 2
Comparing two doses of lenvatinib for thyroid cancer not helped by iodine
This study compares two doses of lenvatinib (24 mg vs 10 mg per day) to see which works better for people with thyroid cancer that no longer responds to radioactive iodine. It's for those whose cancer is growing or causing symptoms.
St Louis, MissouriAges 18 years+ - NCT07068542Recruiting
New drug combo for advanced thyroid cancer
This trial tests a new drug called sacituzumab tirumotecan combined with immunotherapy for people with advanced thyroid cancer that cannot be removed by surgery or has spread. It aims to see if this combination can help shrink tumors or slow down the cancer.
Hangzhou, ZhejiangAges 18 years+ - NCT06902376RecruitingPhase 1
XL092 and cemiplimab for advanced thyroid cancer without BRAF mutation
This trial tests a combination of two drugs, XL092 and cemiplimab, for people with a rare and aggressive type of thyroid cancer called anaplastic thyroid cancer. The drugs aim to shrink tumors before surgery and help the immune system fight the cancer.
Boston, MassachusettsAges 18 years+ - NCT06374602RecruitingPhase 2
Pembrolizumab and lenvatinib for anaplastic thyroid cancer
This trial tests a combination of two drugs, pembrolizumab and lenvatinib, for people with a rare and aggressive thyroid cancer that cannot be removed by surgery. The goal is to see if this treatment can shrink the tumor or slow its growth.
Saint PetersburgAges 18 years+ - NCT06235216RecruitingPhase 2
Sacituzumab govitecan for advanced thyroid cancer
This trial tests a new drug called sacituzumab govitecan for people with advanced thyroid cancer that has stopped responding to standard treatments. It may be an option for those with differentiated thyroid cancer (after certain prior therapies) or anaplastic thyroid cancer (first-line or after one prior treatment).
BarcelonaAges 18 years+ - NCT05024929Recruiting
Test targeted drugs to help radioactive iodine reach thyroid cancer
This study looks at whether certain cancer “targeted therapy” medicines can make radioactive iodine (RAI) therapy work better for thyroid cancer that has spread to the lungs. It also involves taking special whole-body scans to measure how much radioactive iodine gets taken up by the cancer.
San Francisco, CaliforniaAges birth+ - NCT03765333Recruiting
Registering people with thyroid cancer for a study
This study is a registry that collects information about adults with certain types of thyroid cancer. It may help researchers learn more about these cancers and how people are doing over time.
Barcelona, BarcelonaAges 18 years+ - NCT06195228RecruitingPhase 4
Real-world study of genetic types in advanced thyroid cancer
This study looks at how different genetic types of advanced thyroid cancer respond to treatment in real-world settings. It may help doctors choose the best therapy for you based on your tumor’s genetic makeup.
Fuzhou, FujianAges Any age - NCT05604963Recruiting
Half or full thyroid surgery for low-risk thyroid cancer
This study looks at people with low-risk thyroid cancer who have already had (or are about to have) surgery, comparing half-thyroid removal versus full-thyroid removal. It may help doctors choose the safest and most effective surgery for your cancer type and risk level.
Crewe, CheshireAges 16 years+ - NCT05768178RecruitingPhase 2/Phase 3
Vemurafenib plus cobimetinib for BRAF-mutant cancers
This trial tests whether combining two targeted cancer medicines—vemurafenib and cobimetinib—can treat adults whose tumors have a specific “BRAF V600” mutation. You may be screened with blood tests and a tissue biopsy before starting treatment.
BelfastAges 18 years+ - NCT06639191RecruitingEarly Phase 1
Study of a new drug for cancers expressing CD44v6
This trial tests a new radioactive drug called [177Lu]Lu-AKIR001 for patients with certain advanced cancers (like thyroid, head and neck, lung, vulvar, or cervical cancer) that have a specific protein called CD44v6 on their surface. The goal is to see if this treatment can help when standard options have stopped working.
Stockholm, Stockholm CountyAges 18 years+ - NCT07376837Recruiting
Radiofrequency ablation for small low-risk thyroid cancer
This study tests whether radiofrequency ablation (a heat-based treatment applied through the skin) can safely and effectively cure small, low-risk papillary thyroid cancers. It is designed for people whose tumors are small, have not spread, and who either cannot have surgery or prefer not to.
Toronto, OntarioAges 18 years+ - NCT06507878Recruiting
Registry for advanced thyroid cancer treatments
This study collects real-world information from patients with advanced thyroid cancer to better understand how standard treatments and specialized procedures work. Your participation will help improve care for others with this type of cancer.
Houston, TexasAges 18 years+ - NCT07545837Recruiting
Wellness Coaching for Thyroid Cancer Survivors
This study tests whether personalized health coaching helps thyroid cancer survivors stick to their treatment plans and build healthier habits. You'll work with a coach to improve your overall wellness after thyroid cancer treatment.
Jacksonville, FloridaAges 18 years+ - NCT05088187Recruiting
Study of thinking and quality of life after thyroid surgery
This study looks at how thyroid surgery affects thinking (cognition) and day-to-day quality of life. It may help patients and doctors understand what to expect and how to support people after surgery.
StockholmAges 18 years+ - NCT06455371Recruiting
Personalized Levothyroxine Dosing After Thyroid Removal
This study tests a personalized way to dose levothyroxine (thyroid hormone) after total thyroid removal. It aims to find the right dose for each patient, improving energy and well-being.
BergenAges 18 years+ - NCT07440290RecruitingPhase 2/Phase 3
Dabrafenib and trametinib for BRAF V600 cancers
This trial tests two targeted drugs (dabrafenib and trametinib) for patients whose cancer has a specific change in the BRAF gene called V600. These drugs work together to block signals that help the cancer grow. The trial is for children, teenagers, and adults with many types of cancer, except for a few common ones that already have approved treatments.
BelfastAges 1 year+
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Common questions
- Are there clinical trials for anaplastic thyroid cancer?
- Yes. Clin2 currently lists 31 recruiting anaplastic thyroid cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a anaplastic thyroid cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a anaplastic thyroid cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.