Clinical trials
Antibiotic Therapy clinical trials
Below are recruiting antibiotic therapy clinical trials, each written for real people, not researchers. We’re tracking 49 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05678621RecruitingPhase 2/Phase 3
Testing stopping or extending immune treatment to prevent infections
This trial studies whether people with certain blood cancers can safely stop their immune support medicine (immunoglobulin, also called Ig) or whether they should continue. It also tests antibiotic prevention strategies to reduce the risk of serious infections.
Garran, Australian Capital TerritoryAges 18 years+ - NCT05681442RecruitingPhase 4
Antibiotics given in different ways for hospital sepsis
This study tests whether giving certain antibiotics intermittently versus continuously, along with a second antibiotic, works better for hospital-acquired sepsis. It may help doctors choose the most effective way to control serious infections.
AmiensAges 18 years+ - NCT05696093RecruitingPhase 3
Cotrimoxazole for step-down treatment of ventilator pneumonia
This trial tests whether switching from an initial antibiotic to cotrimoxazole (a specific antibiotic combination) can work as well—or better—for ventilator-associated pneumonia in ICU patients. It aims to see if “de-escalating” antibiotics can control the infection while keeping vital signs stable.
AmiensAges 18 years+ - NCT05847322Recruiting
Pertussis challenge study with delayed antibiotic treatment
This study tests how well a “delayed antibiotic” plan works after being intentionally exposed to pertussis (whooping cough). It aims to learn whether delaying antibiotics for a short time is safe and useful, and you may be treated with an antibiotic if you become symptomatic.
Southampton, HampshireAges 18–55 - NCT06451913RecruitingPhase 4
Probiotic for gut health during Lyme disease antibiotics
This trial tests if a probiotic (Saccharomyces boulardii) can help maintain healthy gut bacteria while you take antibiotics for the early skin rash of Lyme disease (erythema migrans). You'll take amoxicillin for 14 days, plus either the probiotic or a placebo.
LjubljanaAges 18 years+ - NCT06743529Recruiting
Immediate or watchful waiting for antibiotics in possible pneumonia
This trial compares starting antibiotics right away versus waiting for more test results in people on a breathing machine who may have pneumonia. The goal is to find out which approach works better without causing harm.
Angers, FranceAges 18 years+ - NCT07202052RecruitingPhase 2/Phase 3
Antibiotics or immunoglobulin for infections in blood cancer
This trial compares two treatments—antibiotics or immunoglobulin (a blood product with infection-fighting antibodies)—to see which better prevents infections in people with certain blood cancers like CLL, multiple myeloma, or non-Hodgkin's lymphoma.
Adelaide, South AustraliaAges 18 years+ - NCT07202065RecruitingPhase 2/Phase 3
Preventing infections with antibiotics or immunoglobulin in blood disorders
This study looks at whether a different dose of IVIg (antibody treatment through the vein) or adding antibiotics can help prevent infections in people with low antibody levels. It's for patients already on steady IVIg who cannot safely stop it.
Adelaide, South AustraliaAges 18 years+ - NCT07202078RecruitingPhase 2/Phase 3
Starting immunoglobulin for infection prevention in hematology
This trial tests whether giving immunoglobulin to adults with low antibody levels can prevent infections. It aims to compare immunoglobulin with antibiotic therapy or no added treatment for people with blood conditions.
Adelaide, South AustraliaAges 18 years+ - NCT07202091RecruitingPhase 2/Phase 3
Stopping or extending immunoglobulin therapy to prevent infections
This trial tests whether it is safe to stop or extend immunoglobulin (Ig) therapy for people with low antibody levels, or if switching to preventive antibiotics works just as well to prevent infections.
Adelaide, South AustraliaAges 18 years+ - NCT06874920Enrolling by invitation
Antibiotic choice based on hospital lab reports in transplant patients with bloodstream infection
This study looks at whether choosing antibiotics based on local hospital lab reports (antibiograms) works well for organ transplant patients who have a single bacteria in their bloodstream. It hopes to find the best way to treat these infections.
MilanAges 18 years+ - NCT07107477RecruitingPhase 3
Tailored therapy for preterm membrane rupture to prolong pregnancy
This trial tests a personalized treatment plan for people whose water breaks too early (before 34 weeks). The goal is to safely extend the pregnancy and improve health outcomes for both the parent and baby, while reducing the use of antibiotics.
BrnoAges 18 years+ - NCT07032506Recruiting
Stent placement after uterine septum surgery
This trial tests whether placing a small stent in the uterus after surgery to remove a uterine septum (a wall of tissue dividing the uterus) can help improve healing and future pregnancy chances. It is for people who have a septum that covers at least half of the uterine cavity.
Little Rock, ArkansasAges 18 years+ - NCT07068607RecruitingPhase 4
Comparing two treatments for H. pylori infection
This study tests whether a new stomach acid medicine called vonoprazan, combined with different antibiotics, works better than standard treatments to clear an H. pylori infection. It is for people who have never been treated for H. pylori and want to try a shorter, simpler treatment course.
Xi'an, ShaanxiAges 18–70 - NCT04669717RecruitingPhase 4
Testing antibiotic dosing alongside periodontal treatment
This study tests how antibiotics should be added to standard gum (periodontal) treatment, including dosing and blood-level timing. It may help people whose gum disease is severe, by improving how antibiotics are used with routine dental care.
Geneva, Canton of GenevaAges 18–80 - NCT03636464Recruiting
Antibiotic testing in people on kidney dialysis
This trial studies how common antibiotics move through the body when someone is on kidney replacement therapy (dialysis), including when dialysis starts during treatment. The results may help doctors choose the right antibiotic dose and timing for better infection treatment.
Abu DhabiAges 18 years+ - NCT07051525Recruiting
Early vs. late stopping of antibiotics for fever in blood cancer treatment
This trial compares stopping antibiotics early (after fever resolves) versus continuing them as usual in adults with blood cancers who develop fever during treatment. It aims to find the best timing to reduce unnecessary antibiotic use.
Melbourne, VictoriaAges 18 years+ - NCT05224401RecruitingPhase 3
Oral antibiotic step-down for ESBL bladder infections
This Phase 3 trial tests whether switching from short-term IV antibiotics to an oral antibiotic combo is safe and effective for ESBL urine infections. It may help you avoid staying on IV antibiotics as long, if your bacteria are the right match.
HelsingborgAges 18–130 - NCT07230041Recruiting
Antibiotic removal during kidney therapy in the ICU
This trial studies how much certain antibiotics (meropenem, linezolid, and daptomycin) are removed when you're on a special blood-filtering machine called continuous renal replacement therapy (CRRT) for severe kidney injury. The results could help doctors give the right dose of antibiotics to treat infections effectively.
Milan, ItaliaAges 18 years+ - NCT05052619Recruiting
Check lactate-guided prevention after pancreas surgery
This study looks at whether measuring a blood test called lactate after surgery can help prevent infections inside the belly. You may be eligible if you recently had pancreas surgery and your lactate rises above a certain level within 24 hours.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07077122Recruiting
Comparing five gum disease treatments
This trial tests five different non-surgical gum treatments to see how they affect overall health. It may be a good fit for people with advanced gum disease who do not smoke heavily or take certain medications.
AthensAges Any age - NCT06451172RecruitingEarly Phase 1
New antibiotic eye drops for drug-resistant eye infections
This trial tests a new type of antibiotic eye drop for people with serious eye infections that don't respond to standard antibiotics. It aims to see if these drops can safely treat the infection and help improve vision.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07094984Recruiting
Clearing resistant gut bacteria: three FMT methods
This trial tests three different ways to clear antibiotic-resistant bacteria from your gut using fecal microbiota transplant (FMT). It may help if you have a confirmed resistant infection and are looking for a treatment to reduce the risk of future infections.
WarsawAges 18 years+ - NCT06738771Recruiting
Antibiotic treatment for tough Pseudomonas infections
This study tests a specific antibiotic plan for adults with a hard-to-treat Pseudomonas infection that needs IV medicine. It aims to find the best way to treat these serious infections.
AmiensAges 18 years+
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Common questions
- Are there clinical trials for antibiotic therapy?
- Yes. Clin2 currently lists 49 recruiting antibiotic therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a antibiotic therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a antibiotic therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.