Clinical trials
Aortic Diseases clinical trials
Below are recruiting aortic diseases clinical trials, each written for real people, not researchers. We’re tracking 156 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06953206Recruiting
Long-term study of a new heart valve for aortic stenosis
This study is testing a new heart valve called the SAPIEN 3 Ultra RESILIA valve for people with severe aortic stenosis. Researchers want to see how well it works and how safe it is over 10 years after a minimally invasive valve replacement procedure called TAVI.
Bad Oeynhausen, North Rhine-WestphaliaAges 18 years+ - NCT07611968Recruiting
Physician-Modified Stent Grafts for Aortic Aneurysms
This trial tests a custom-made stent graft (a tube that reinforces the aorta from inside) for patients with large aortic aneurysms who may be too sick for traditional open surgery. The goal is to prevent rupture and complications while avoiding major surgery.
Jacksonville, FloridaAges 50 years+ - NCT05777681Recruiting
Treating infection in the aorta or iliac arteries
This trial studies a surgical product made from animal tissue to treat infections involving the aorta and nearby blood vessels. It may help people whose grafts or weak spots (aneurysms) are infected.
RomeAges 18 years+ - NCT07107568Recruiting
Testing ways to check heart arteries before valve replacement
This trial compares different methods to evaluate coronary artery disease in patients planning to have a transcatheter aortic valve replacement (TAVR) for severe aortic stenosis. The goal is to find out if a less invasive approach is as safe and effective as the standard one.
InnsbruckAges 18 years+ - NCT05635227Recruiting
Medications during heart surgery to help control breathing and circulation
This study looks at whether giving dexamethasone and olanzapine during certain heart surgeries can improve how blood flow and ventilation (breathing support) are managed. It’s meant to see if these medicines help the body handle heart-lung bypass more safely.
CopenhagenAges 18 years+ - NCT06286358Recruiting
Heart and aorta imaging study for valve disease
This study uses a special recording device to see if heart and aorta problems can be detected earlier. It may help people with aortic valve disease or enlarged aorta decide on treatment.
BrusselsAges 18 years+ - NCT06753227Enrolling by invitation
Comparing ways to measure valve pressure after TAVI
This trial looks at how well a new method (using echo) compares to the standard invasive method for measuring pressure across the new valve after TAVI. It may help doctors monitor your valve function with less risk.
Munich, BavariaAges 18 years+ - NCT07099859RecruitingPhase 4
Losartan after aortic valve surgery for severe leakage
This trial tests if the drug losartan can help the heart recover better after surgery to replace a leaky aortic valve. It may reduce strain on the heart and improve long-term outcomes.
São Paulo, São PauloAges 18–85 - NCT03600662Recruiting
Heart valve reconstruction using your own tissue
This trial studies a surgery to repair the aortic valve using tissue taken from your body. It may help people with significant valve problems, by testing whether this reconstruction approach works and is safe.
Munich, BavariaAges 50 years+ - NCT04454177Recruiting
Smartwatch help to discharge earlier after valve replacement
This study tests whether using a smartwatch can safely help people leave the hospital earlier after a transcatheter aortic valve replacement (TAVR). It checks comfort, safety, and follow-up at home.
Hangzhou, ZhejiangAges 18 years+ - NCT07276711Recruiting
Protecting brain during TAVR with EmStop device
This trial tests a new device (EmStop) that helps protect your brain during TAVR (a type of heart valve replacement). The device is placed in arteries to catch any debris that might break loose during the procedure, potentially reducing the risk of stroke.
New Orleans, LouisianaAges 22 years+ - NCT06336213Recruiting
Using a blood test to guide antibiotics in aorta surgery
This trial checks if a blood test called presepsin can help doctors decide when to use antibiotics in patients having surgery on the chest's main artery (the thoracic aorta). It is for people with an aneurysm or tear in that artery.
Moscow, MoscowAges 18–75 - NCT06257043Recruiting
Real-world study of aortic valve replacement
This trial is studying how well a new type of heart valve works in real-life patients with aortic valve disease. It will help doctors understand if this valve is safe and effective for people who need a procedure called TAVR (transcatheter aortic valve replacement).
Xi'an, ShaanxiAges 18 years+ - NCT06126367Recruiting
Study on lipoprotein(a) and clot breakdown in heart disease
This trial looks at how a type of fat in the blood called lipoprotein(a) and your body's ability to break down clots affect heart disease or heart valve disease. It is for people who are already taking certain cholesterol-lowering medicines or have severe aortic valve narrowing from calcium buildup.
StevenageAges 18 years+ - NCT06189976Recruiting
Can a quick heart pacing test after TAVI predict pacemaker need?
This study checks if a short, controlled heart pacing procedure right after your TAVI (a valve replacement) can tell doctors whether you might need a permanent pacemaker later. It aims to help avoid unnecessary pacemakers.
BrusselsAges 18 years+ - NCT05777447Recruiting
Study for infected aorta/iliac aneurysm after in-place repair
This study looks at treatment outcomes for people whose aorta or iliac artery aneurysm became infected (a “mycotic” aneurysm) and who were treated with an in-place repair. It may help doctors understand the best way to manage this rare condition after surgery.
Roma, RMAges 18 years+ - NCT06318780Recruiting
Comparing imaging methods to find leaks after aortic repair
This study compares three different imaging methods (dynamic CT, contrast-enhanced ultrasound, and CT angiography) to better identify and characterize endoleaks—small leaks that can happen after aortic aneurysm repair. The goal is to find the most accurate way to detect these leaks so patients can get the right treatment sooner.
Amiens, PicardieAges 18 years+ - NCT06816485Recruiting
New balloon safety in TAVI for severe aortic stenosis
This trial studies a new balloon used during a TAVI procedure to replace your aortic valve without open-heart surgery. It aims to see if the balloon is safe and works well for people with severe aortic stenosis.
BarcelonaAges 18 years+ - NCT06514170Recruiting
Stomach and bowel function after aortic surgery
This study looks at how stomach and bowel function changes after major aortic surgery. It may help doctors understand and prevent digestive problems in patients who need extended time on a ventilator after surgery.
Mexico City, TlalpanAges 18 years+ - NCT06689839Recruiting
Testing a new filter to prevent stroke during heart valve replacement
This trial tests a new filter device designed to catch debris that might travel to the brain during a minimally invasive aortic valve replacement (TAVR). The goal is to see if it can help reduce the risk of stroke.
Naples, FloridaAges 50 years+ - NCT07566624Recruiting
Registry study of Hydra heart valve replacement procedure
This study tracks patients who receive a Hydra artificial heart valve to replace a severely narrowed aortic valve. Researchers will follow your progress to understand how well the device works and its safety in real-world use.
Fuencarral-El PardoAges 18 years+ - NCT06001073Recruiting
Heart and brain disease health prediction study
This study uses advanced health data to predict how heart and brain conditions may progress. It aims to help doctors provide better care for people with these diseases.
Xi'an, ShaanxiAges 3–80 - NCT06377449Recruiting
Lung ultrasound for better outcomes after heart surgery
This study tests whether using ultrasound to look at the lungs during and after heart surgery helps improve recovery. You may be eligible if you are having open-heart surgery with a heart-lung machine and meet certain health criteria.
Saint Petersburg, Sankt-PeterburgAges 18 years+ - NCT06358248Recruiting
Registry for customized endografts in complex aortic aneurysms
This registry tracks patients with complex abdominal aortic aneurysms who receive a physician-modified endograft. It aims to collect data on how well this tailored device works to treat aneurysms that standard grafts cannot handle.
PadovaAges 18–100
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Common questions
- Are there clinical trials for aortic diseases?
- Yes. Clin2 currently lists 156 recruiting aortic diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aortic diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aortic diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.