Clinical trials
ARDS (Moderate or Severe) clinical trials
Below are recruiting ards (moderate or severe) clinical trials, each written for real people, not researchers. We’re tracking 1,471 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05428345Recruiting
Shot of vedolizumab skin injection for active bowel inflammation
This study tests whether a weekly/regular skin injection version of vedolizumab can help adults with moderate to severe ulcerative colitis or Crohn’s disease who did not fully respond to other treatments or TNF blockers. It may help by moving you from an intravenous (IV) infusion to a self/clinic injection option.
Goyang-si, Gyeonggi-doAges 18 years+ - NCT05591924Recruiting
Bioinformatics study in adults with very early severe ICU illness
This trial studies how early severe illness in the ICU can be understood and tracked using health data (bioinformatics/informatics). It may help improve care decisions for people who arrive to the ICU soon after an emergency department visit.
London, OntarioAges 18 years+ - NCT06104839RecruitingPhase 2
Oral NXC-736 for moderate to severe alopecia areata
This trial tests an oral medication called NXC-736 for people with moderate to severe alopecia areata. It aims to see if the drug is safe and can help regrow hair.
SeoulAges 19–65 - NCT05837897RecruitingPhase 3
Vedolizumab for adults with moderate-to-severe Crohn’s
This Phase 3 study tests whether vedolizumab can better control moderate-to-severe Crohn’s disease in adults whose symptoms haven’t improved enough with other treatments. You’d need to meet specific symptom scores, recent colonoscopy findings, and safety checks (including infections and vaccination status).
Hefei, AnhuiAges 18–80 - NCT06072690Recruiting
COPD and Heart Health Study
This study looks at how COPD affects your breathing and heart health. It is for people who are newly diagnosed with COPD and have a history of smoking.
Kaunas, Kaunas CountyAges 40 years+ - NCT06062888RecruitingPhase 2/Phase 3
Testing fresh frozen plasma for traumatic brain injury
This trial tests whether giving fresh frozen plasma (a blood product) soon after a traumatic brain injury can help people recover better. It is for adults aged 18 to 65 with moderate to severe TBI confirmed by CT scan.
Chicago, IllinoisAges 18–65 - NCT06065046RecruitingPhase 2
Baricitinib for traumatic brain bleeding
This trial tests if baricitinib, an anti-inflammatory drug, can help people with bleeding in the brain from a head injury. It is for adults with moderate to severe traumatic brain injury who are not immediately having surgery.
Xi'an, ShaanxiAges 18–80 - NCT06023030Recruiting
Observing how upadacitinib works for Crohn's disease in Japan
This study is for people with moderate to severe Crohn's disease who are starting a medication called upadacitinib. Researchers will watch how the disease changes over time and check for any side effects. It's an observational study, meaning you'll keep getting your regular treatment.
Anjo-shi, Aichi-kenAges 15 years+ - NCT05995964RecruitingPhase 2
Study of two new medicines for eczema
This study tests two new study medicines (PF-07275315 and PF-07264660) for people with moderate to severe eczema that hasn't responded well to other treatments, including biologics. The goal is to see if these medicines can help reduce itching and clear the skin.
Birmingham, AlabamaAges 18 years+ - NCT05995353RecruitingPhase 3
Risankizumab for children with moderate to severe Crohn's
This study tests a new medicine called risankizumab for children with moderate to severe Crohn's disease. It is given as an IV infusion or a shot under the skin to see if it can reduce inflammation and improve symptoms.
Phoenix, ArizonaAges 2–17 - NCT05987449RecruitingPhase 1/Phase 2
Study of NXT007 for people with hemophilia A
This study tests a new medicine called NXT007 for people with moderate or severe hemophilia A. The goal is to see if it is safe, well-tolerated, and can help prevent or reduce bleeding episodes, possibly reducing the need for standard treatments. You may be able to join if you have hemophilia A with or without inhibitors and meet other health requirements.
Sacramento, CaliforniaAges 2–59 - NCT05974202Recruiting
Brain stimulation and therapy for cocaine use
This study tests a combination of brain stimulation (rTMS) and talk therapy (CBT) to help people reduce cocaine use. It's for adults who want treatment and use cocaine at least once a week.
New York, New YorkAges 22–65 - NCT05923073RecruitingPhase 3
Guselkumab for children with active Crohn’s disease
This Phase 3 trial tests guselkumab to treat children with moderately to severely active Crohn’s disease and ongoing inflammation in the bowel. If you qualify, the study will check whether the medicine can improve symptoms and healing, especially in children who did not respond to other treatments.
Los Angeles, CaliforniaAges 2–17 - NCT05790239RecruitingPhase 2
MDMA therapy sessions for veterans with PTSD
This Phase 2 trial tests whether therapy assisted by MDMA can reduce symptoms of moderate to severe post-traumatic stress disorder (PTSD) in eligible veterans. It includes supervised therapy sessions and extra study visits with video recording to track changes over time.
Los Angeles, CaliforniaAges 18 years+ - NCT05778188RecruitingPhase 2
RLS-0071 for newborns with moderate or severe HIE
This trial studies whether RLS-0071 is safe and can help some newborns with moderate or severe hypoxic-ischemic encephalopathy (HIE), a brain injury caused by low oxygen around birth. Babies in the study also receive standard whole-body cooling (therapeutic hypothermia), and the researchers will watch for side effects and early signs of benefit.
Little Rock, ArkansasAges Up to 10 hours - NCT05735483Enrolling by invitationPhase 3
Long-term lebrikizumab study for moderate to severe eczema
This Phase 3 trial studies whether lebrikizumab is safe and continues to work over the long term for children and teens with moderate-to-severe atopic dermatitis (eczema). It’s meant for people who already finished a related earlier study and can safely continue.
Birmingham, AlabamaAges 6 months–18 years - NCT05732727RecruitingPhase 3
Stronger BP lowering using diuretics in kidney disease
This Phase 3 trial compares a plan that uses diuretics (water pills) to lower blood pressure more, versus usual blood pressure care, in people with uncontrolled hypertension and moderate-to-severe chronic kidney disease. It may help your blood pressure control while monitoring safety closely because kidney function changes how medicines work.
AngersAges 18 years+ - NCT05689151Recruiting
Abrocitinib for adult moderate to severe atopic eczema
This study tests how well abrocitinib (a prescription medicine) works for adults with moderate to severe atopic dermatitis (atopic eczema). You may join if you meet the study’s health and consent requirements and your doctor believes abrocitinib is an appropriate option for you.
Amiens, SommeAges 18 years+ - NCT05539196Recruiting
Registry for Exablate treatment in Parkinson’s with medication problems
This trial is a real-world registry that follows people with Parkinson’s who are planning to get an Exablate 4000 procedure (a focused ultrasound treatment) for one-sided symptoms that are difficult to control with medication. It mainly checks outcomes and safety over time, helping doctors understand how well this treatment works in everyday care.
Baltimore, MarylandAges 30–99 - NCT05529927RecruitingPhase 2
Dexamphetamine given long-acting to reduce cocaine use
This Phase 2 study tests whether a long-acting form of dexamphetamine can reduce cocaine use in people with moderate to severe cocaine use disorder. It also checks safety, including heart and mental health side effects, while you attend study visits regularly.
The HagueAges 18 years+ - NCT04974593RecruitingPhase 3
Test breath testing to guide a lactose-free diet in IBS
This trial studies whether a breath test (hydrogen/methane lactose testing) can predict who with IBS will improve on a lactose-free diet. If you have moderate-to-severe IBS and regularly eat lactose-containing foods, the test result may help tailor your diet approach.
Jette, Brussels CapitalAges 18–75 - NCT05120752RecruitingPhase 3
Low FODMAP diet trial for IBS without lactose intolerance
This trial tests whether eating a low-FODMAP diet can reduce IBS symptoms in people who do not have lactose intolerance. It aims to improve moderate-to-severe IBS symptoms by changing what kinds of carbohydrates you eat.
Jette, Brussels CapitalAges 18–75 - NCT05369052RecruitingPhase 3
New antibiotic for moderate or severe diabetic foot infections
This Phase 3 trial tests a new medicine (contezolid acefosamil, and contezolid) to treat moderate or severe diabetic foot infections. It compares the new treatment to linezolid to see which works better and is safer for adults.
Corona, CaliforniaAges 18 years+ - NCT05076175RecruitingPhase 2/Phase 3
Oral ozanimod for children with moderate to severe ulcerative colitis
This trial tests whether an oral medicine called ozanimod can improve ulcerative colitis (UC) in children whose disease is moderate to severe. It’s meant for kids who didn’t fully respond—or couldn’t tolerate—standard UC treatments.
Phoenix, ArizonaAges 2–17
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Common questions
- Are there clinical trials for ards (moderate or severe)?
- Yes. Clin2 currently lists 1,471 recruiting ards (moderate or severe) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ards (moderate or severe) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ards (moderate or severe) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.