Clinical trials
Atrial Fibrillation Ablation clinical trials
Below are recruiting atrial fibrillation ablation clinical trials, each written for real people, not researchers. We’re tracking 291 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07217067RecruitingPhase 2
Study of PKN605 for people with atrial fibrillation
This trial tests a new medicine called PKN605 for people with atrial fibrillation (irregular heartbeat). The goal is to see if it can safely help control heart rhythm. You will need to have had at least two AF episodes recently and meet other heart health criteria.
Tupelo, MississippiAges 18 years+ - NCT06598280Recruiting
Going home same day vs staying overnight after afib ablation
This trial compares whether it is safe to go home a few hours after a heart procedure for atrial fibrillation (afib) versus staying in the hospital overnight. It will help doctors understand which approach is better for your recovery.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT06322017Recruiting
Early vein isolation for atrial fibrillation in older adults
This study compares doing vein isolation soon after diagnosis versus usual care in people 75+ with new or early atrial fibrillation. The goal is to see if early treatment prevents the condition from getting worse and improves quality of life.
Nantes, Loire AtlantiqueAges 75 years+ - NCT07181590Recruiting
Balloon-based ablation for atrial fibrillation: post-approval study
This trial tests a balloon catheter that uses pulsed field energy to treat atrial fibrillation (AF) in people who have tried medication without success. It aims to see how well it works in real-world use.
LinzAges 18 years+ - NCT07171463Recruiting
New ablation for paroxysmal atrial fibrillation
This trial tests a new treatment that uses two types of energy (pulsed field and radiofrequency) to fix the heart's electrical signals in people with paroxysmal atrial fibrillation (AFib that comes and goes). It aims to be more effective and safer than standard ablation alone.
Rzeszów, Podkarpackie VoivodeshipAges 18 years+ - NCT07156877Recruiting
Balloon Catheter Ablation for Atrial Fibrillation
This study tests a new balloon catheter that uses pulsed electric fields to isolate the veins that carry blood from your lungs to your heart. It may be a treatment option for people with atrial fibrillation who are scheduled for an ablation procedure.
BrugesAges 18 years+ - NCT04281329Recruiting
CT and heart MRI add-on for atrial fibrillation ablation
This trial studies whether CT scans and heart MRI scans (done around the time of atrial fibrillation ablation) can help care planning and results. It may help your team better understand your heart before and after the procedure.
ParisAges 18 years+ - NCT07141745Recruiting
Comparing energy types for repeat atrial fibrillation treatment
This trial compares two different energy methods (electroporation vs radiofrequency ablation) guided by 3D imaging for people who have had a prior ablation for atrial fibrillation but still have recurrences. It aims to find which method is safer and more effective for repeat procedures.
WroclawAges 18–85 - NCT07130773Recruiting
Comparing two catheter types for atrial fibrillation ablation
This trial compares two types of special catheters (thin tubes) used during a procedure called ablation to treat atrial fibrillation (irregular heartbeat). It aims to see which catheter works better during the procedure, and may help improve future treatments for people with heart rhythm problems.
Lugano, Canton TicinoAges 18 years+ - NCT07116525Recruiting
Study of heart mapping for abnormal rhythms
This trial tests a special catheter to map abnormal heart rhythms like ventricular tachycardia or atrial fibrillation. It may help patients who need a procedure to find and treat the source of these fast or irregular heartbeats.
BrugesAges 18 years+ - NCT07118488Recruiting
New ablation approach for persistent atrial fibrillation with heart issues
This study tests a new way to treat long-lasting atrial fibrillation using focused energy (pulse field ablation) guided by special heart mapping. It may help people who have not improved with medications or have other heart problems like heart failure.
Madrid, MadridAges 18–80 - NCT07122336Recruiting
A better way to treat persistent atrial fibrillation
This trial tests a new method to treat persistent atrial fibrillation (a long-lasting irregular heartbeat) to see if it helps patients who haven't been helped by medication. It focuses on cleaning up the back wall of the heart to restore a normal rhythm.
ShanghaiAges 18–80 - NCT07106970Recruiting
Comparing two ablation approaches for persistent atrial fibrillation
This trial tests whether adding extra ablation lines to the standard pulmonary vein isolation procedure is more effective for people with persistent atrial fibrillation that hasn't been helped by medications. The goal is to improve symptoms like palpitations, fatigue, and shortness of breath.
BeijingAges 18–80 - NCT07109141Recruiting
Registry of Heart Rhythm Fix Procedures Using Pulsed Field Ablation in Poland
This study tracks people who have a procedure called pulsed field ablation to fix an abnormal heart rhythm (atrial arrhythmia). It's a registry, meaning researchers will collect information to learn more about how well the treatment works and how safe it is.
Wroclaw, Lower Silesian VoivodeshipAges 18 years+ - NCT07095959Recruiting
Ethanol vein infusion plus pulsed field ablation for paroxysmal AF
This study compares two treatments for paroxysmal atrial fibrillation (AF that comes and goes): using pulsed electric field ablation alone versus combining it with ethanol infusion into a specific vein. The goal is to see which approach works better for first-time ablation patients.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07100483Enrolling by invitation
Comparing surgery methods for atrial fibrillation
This trial studies different surgical techniques for treating atrial fibrillation during heart surgery. It may help people with a history of AFib who are already scheduled for open-heart surgery.
Grand Rapids, MichiganAges 18–85 - NCT07064616Recruiting
Pulsed field vs. cryoballoon ablation for persistent atrial fibrillation
This trial compares two techniques—pulsed field ablation and cryoballoon ablation—to treat persistent atrial fibrillation (a type of irregular heartbeat that lasts less than a year). The goal is to see which method works better and is safer for patients.
Sagamihara, KanagawaAges 18–85 - NCT07047235Recruiting
Targeted ablation for persistent atrial fibrillation
This trial is testing a specific approach to catheter ablation for people with persistent atrial fibrillation. It aims to improve how abnormal heart tissue is targeted to help restore a normal rhythm.
LondonAges 18 years+ - NCT07036965Recruiting
Comparing two types of ablation catheters for atrial fibrillation
This trial tests two different catheters that use pulsed field energy to treat atrial fibrillation (a heart rhythm problem). It aims to find which one works better for people who need blood thinners but have a high risk of bleeding.
HangzhouAges 118 years+ - NCT07018596Recruiting
New pulsed field ablation for paroxysmal atrial fibrillation
This trial tests a new type of heart procedure that uses gentle electrical pulses to fix abnormal signals in the upper chambers of the heart for people with a specific type of atrial fibrillation that comes and goes on its own. It may be an option if your AFib episodes stop within 7 days and medications haven't helped enough.
Prague, RoentgenovaAges 18–85 - NCT06989775Recruiting
BoxX-NoAF Trial: Preventing Stroke During Heart Surgery
This trial tests a device to close a small pouch in the heart during planned bypass surgery, to help prevent future strokes. It is for people who have never had an irregular heartbeat and are at higher stroke risk due to age and other factors.
Scottsdale, ArizonaAges 65 years+ - NCT06985901Recruiting
Pulsed-field ablation for persistent atrial fibrillation
This trial tests a new type of ablation (pulsed-field) to treat persistent atrial fibrillation (AFib) that lasts more than 7 days. You may qualify if you have symptoms and haven't had other heart ablation procedures except for one specific type.
NiceAges 18 years+ - NCT06988202Enrolling by invitation
Comparing repeat ablation methods for atrial fibrillation
This trial compares different techniques for a second heart ablation procedure in people with atrial fibrillation (AFib) who have already had one ablation. It aims to find the best approach to stop AFib from coming back.
Rochester, New YorkAges 18 years+ - NCT05266144Recruiting
Catheter ablation for non-valvular atrial fibrillation
This trial studies catheter ablation, a procedure that targets heart rhythm triggers, for people with atrial fibrillation (an irregular heartbeat). It may help improve rhythm control, but you must meet specific heart and testing requirements and avoid certain conditions.
Beijing, Beijing MunicipalityAges 18–80
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Common questions
- Are there clinical trials for atrial fibrillation ablation?
- Yes. Clin2 currently lists 291 recruiting atrial fibrillation ablation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation ablation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation ablation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.