Clinical trials
Atrial Fibrillation Ablation clinical trials
Below are recruiting atrial fibrillation ablation clinical trials, each written for real people, not researchers. We’re tracking 291 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05115214Recruiting
Device test for treating irregular heartbeat with AF ablation
This trial studies a heart procedure using the Affera SpherePVI system to treat paroxysmal (comes and goes) or persistent atrial fibrillation. It’s for people who still have symptoms despite at least one anti-arrhythmia medicine, and who are good candidates for catheter ablation.
PragueAges 18–75 - NCT05009797Recruiting
Study follow-up after catheter ablation for atrial fibrillation
This trial is looking at what happens after a heart procedure called catheter ablation for atrial fibrillation (an irregular heartbeat). It mainly collects follow-up outcomes to better understand recovery and results for patients.
LilleAges 18 years+ - NCT05014802Recruiting
MRI scans before heart surgery to predict post-surgery atrial fibrillation
This study uses an MRI scan before heart surgery to look for heart scarring that may predict who will develop atrial fibrillation afterward. Knowing the risk ahead of time could help doctors monitor you more closely and plan prevention.
Covington, LouisianaAges 40–120 - NCT04823299Recruiting
Atrial fibrillation ablation using two different energy types
This trial tests whether one ablation approach works better than another for paroxysmal (intermittent) atrial fibrillation by targeting the heart’s “triggers” and “substrate” (where the rhythm problem is). If you qualify, you’ll be randomly assigned to one of two ablation energy methods during a pulmonary vein isolation procedure.
Ottawa, OntarioAges 18 years+ - NCT04685317Recruiting
Sentinel brain-protection device during atrial fibrillation ablation
This trial tests whether a specialized “brain protection” device can improve safety during atrial fibrillation (AF) catheter ablation. It may help reduce the risk of stroke or related complications while treating AF.
Rochester, MinnesotaAges 18 years+ - NCT04529785Recruiting
Tested added ethanol vein treatment during repeat atrial fibrillation ablation
This trial compares two ways to help stop atrial fibrillation during a repeat procedure: standard vein isolation only versus standard isolation plus an added medicine (ethanol) into the vein of Marshall. It aims to see whether the added step improves results when atrial fibrillation returns after a previous successful treatment.
Bruges, Please SelectAges 18 years+ - NCT04404465Enrolling by invitation
Test blood/heart signals to understand atrial fibrillation changes
This study looks at early changes in the heart related to atrial fibrillation (AF) using health data and biomarkers. It aims to find better ways to predict or understand AF, especially around procedures like ablation or cardioversion.
San Francisco, CaliforniaAges 18 years+ - NCT04148625Enrolling by invitation
Sub-xiphoid hybrid maze for persistent atrial fibrillation after failed ablation
This trial studies a hybrid heart procedure to treat persistent atrial fibrillation in people whose previous catheter ablation did not work. It aims to improve heart rhythm and reduce ongoing symptoms by using a planned combination of techniques and careful follow-up.
Ages 18–80 - NCT04088071Recruiting
Ablation for heart rhythm problems using a specific technology
This study looks at how well catheter ablation works for treating certain heart rhythm disorders (like atrial fibrillation or ventricular arrhythmias) using a specific brand of catheters. The aim is to gather real-world data to better understand the procedure's outcomes.
Birmingham, AlabamaAges 18 years+ - NCT03546374Recruiting
Stop a common heart rhythm with surgery add-on therapy
This study looks at whether an added heart device approach around the time of planned open-heart surgery can help treat non-paroxysmal atrial fibrillation (AF), a long-lasting irregular heartbeat. It may help lower ongoing AF burden in people who also need non-emergency heart surgery.
Palo Alto, CaliforniaAges 18 years+ - NCT03444337Recruiting
High-resolution MRI before a special heart ablation for atrial fibrillation
This study uses high-resolution MRI scans to get a detailed picture of the heart before a special type of ablation for atrial fibrillation (an irregular heartbeat). The goal is to help doctors target the treatment more precisely.
Columbus, OhioAges 18 years+ - NCT05928728RecruitingPhase 3
Colchicine for people with certain irregular heartbeats
This trial tests whether colchicine can help people with paroxysmal or persistent atrial fibrillation (AF), a type of irregular heartbeat, after a successful cardioversion. It may help reduce future AF problems, depending on the results.
HellerupAges 18 years+ - NCT05598632Recruiting
People with atrial fibrillation registry to study stroke risk
This registry study follows people with atrial fibrillation to learn which risk factors are linked to stroke or blood clots traveling through the body. Your information helps improve how doctors predict risk and choose prevention strategies.
Beijing, Beijing MunicipalityAges 18–120 - NCT07649109RecruitingPhase 4
Heart Device Detected Irregular Heartbeats: Treatment Study
This study follows patients who have a heart rhythm device (pacemaker, defibrillator, or resynchronization device) and have experienced brief episodes of fast irregular heartbeats detected by the device. The study compares treatment approaches to understand which helps patients stay healthier and feel better.
TaipeiAges 18 years+ - NCT07575867Recruiting
Reduced Blood Thinner Strategy After Heart Device Closure
This trial tests whether patients who receive a special device to close a hole in the heart (to prevent stroke from irregular heartbeat) can safely take fewer blood-thinning medications afterward. The study compares taking a standard blood thinner for 3 months versus taking aspirin only, to see which approach works best with fewer bleeding risks.
MoscowAges 18 years+ - NCT07281898Recruiting
Burst stimulation for paroxysmal atrial fibrillation
This trial tests a special type of pacing called burst stimulation to see if it can help people with paroxysmal atrial fibrillation (AF) who are already scheduled for their first catheter ablation. The goal is to improve outcomes and reduce AF episodes.
Wuhan, HubeiAges 18–80 - NCT06929897Enrolling by invitation
Comparing Two Ablation Methods for Persistent Atrial Fibrillation
This study compares two types of ablation (a procedure that uses energy to fix irregular heartbeats) for people with persistent atrial fibrillation. It tests whether adding extra treatment to the back of the heart's left upper chamber helps improve outcomes compared to standard treatment alone.
SeoulAges 20–80 - NCT03091452Recruiting
Atrial fibrillation surgery registry for people treated with ablation
This study is a real-world registry that collects health information from people who have atrial fibrillation and were treated with a heart surgery procedure called ablation. It may help doctors better understand outcomes and care for people with this condition.
München, BavariaAges 18–100 - NCT04240366Recruiting
Extra left atrial appendage treatment during AF ablation
This trial tests whether adding treatment to the left atrial appendage during a standard catheter ablation helps people with persistent atrial fibrillation (AF). It may improve how well AF is controlled, but you must meet specific heart rhythm and heart scan measurements to join.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT07275151Recruiting
Testing a new heart procedure for atrial fibrillation
This trial tests a new method called pulsed field ablation (PFA) to treat irregular heartbeats (atrial fibrillation) by isolating the veins that carry blood to your heart. It aims to see how well this procedure works and if it's safe for you.
Ypsilanti, MichiganAges 21 years+ - NCT07077811Enrolling by invitation
Pulsed field ablation for heart failure with preserved pumping strength
This trial tests a new procedure called pulsed field ablation for people who have both persistent atrial fibrillation and a type of heart failure (HFpEF). It aims to see if this ablation safely helps control the heart rhythm.
Nantong, JiangsuAges 18–80 - NCT06716021RecruitingPhase 3
Etripamil for rapid heart rate in atrial fibrillation
This trial tests a medication called etripamil to see if it can quickly slow down a rapid heart rate during episodes of atrial fibrillation. It may help people who have frequent, long-lasting episodes with a fast heartbeat.
West Hills, CaliforniaAges 18 years+ - NCT06152406Recruiting
Ablate and Pace HIS for atrial fibrillation and heart failure
This study tests a new approach called 'Ablate and Pace HIS' for people with atrial fibrillation and heart failure who haven't improved with other treatments. It combines a heart ablation procedure with a special type of pacing to help your heart pump more efficiently and reduce symptoms.
Leicester, LeicestershireAges 18–100 - NCT05777551Recruiting
High-power short treatment for irregular heartbeat
This trial studies a specific heart-rhythm procedure that uses higher power for a shorter time to treat atrial fibrillation (AF), an irregular heartbeat. It may help some people control AF and reduce rhythm episodes, while doctors compare outcomes using their chosen approach.
ParisAges 18–80
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Common questions
- Are there clinical trials for atrial fibrillation ablation?
- Yes. Clin2 currently lists 291 recruiting atrial fibrillation ablation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation ablation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation ablation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.