Clinical trials
Atrial Fibrillation Ablation clinical trials
Below are recruiting atrial fibrillation ablation clinical trials, each written for real people, not researchers. We’re tracking 291 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06324201Recruiting
Long-term safety of a new ablation system for paroxysmal AF
This study tests a new system (QDOT MICRO and VISITAG SURPOINT) used during a catheter ablation procedure to treat atrial fibrillation (AF). It aims to see how safe and effective it is over the long term for people whose AF comes and goes and hasn't been controlled by medication.
Birmingham, AlabamaAges 18 years+ - NCT06308094Recruiting
CT scan to measure heart health before AF ablation
This trial uses a special CT scan to measure how much extra fluid is in your heart muscle. It aims to help doctors better understand and treat your atrial fibrillation before you have a procedure called ablation.
Baltimore, MarylandAges 21 years+ - NCT06299514Recruiting
Pacemaker and ablation for heart failure with atrial fibrillation
This trial tests if a pacemaker plus an ablation procedure can improve heart failure symptoms in people with atrial fibrillation. It is for those with moderate to severe heart failure who are already on the right medications.
Victoria, British ColumbiaAges 18 years+ - NCT06249269Recruiting
Lifestyle Change to Improve AF Ablation Results
This trial tests whether a healthy lifestyle program (including exercise and weight loss) can help people with atrial fibrillation (AF) who are overweight or have related health risks. You will have a catheter ablation procedure, and the study will see if lifestyle changes improve your heart's rhythm long-term.
Calgary, AlbertaAges 18 years+ - NCT06212791Recruiting
Exercise MRI Study of Heart Function After Ablation
This study uses an exercise MRI to look at how the upper chambers of the heart (left atrium) work after ablation for atrial fibrillation. It may help doctors understand if the procedure improves heart function during exercise.
Richmond, VirginiaAges 18 years+ - NCT06165510Recruiting
Convergent ablation and left atrial appendage isolation for persistent AF
This trial tests a two-step procedure for persistent atrial fibrillation that combines a heart ablation with isolation of a small heart pouch. It aims to see if this approach is more effective than standard care.
LondonAges 18–80 - NCT06061978Recruiting
Pacing after a heart procedure for rapid atrial fibrillation
This trial studies whether a special type of pacing (stimulating the heart's natural electrical system) works better than standard pacing after a procedure to control very fast heart rhythms. It's for people who already have a pacemaker and are getting a specific treatment for atrial fibrillation.
CaenAges 18 years+ - NCT02997254Recruiting
Testing computer methods that analyze atrial fibrillation heart signals
This study compares different computer “analysis methods” that look at real-time heart recordings from people with atrial fibrillation. It may help improve how atrial fibrillation is evaluated during/after an ablation procedure.
Stanford, CaliforniaAges 21–90 - NCT05371405Recruiting
Using computer learning to improve care for atrial fibrillation patients
This study uses machine learning (computer pattern-finding) to better understand atrial fibrillation and guide care around the time of an ablation procedure. It may help refine how doctors treat certain AF patients based on their heart patterns.
Stanford, CaliforniaAges 22–80 - NCT06056271Recruiting
Tracking AI use during AF ablation in real-world care
This trial is for people with atrial fibrillation (AF) who are having or recently had a catheter ablation procedure. It looks at how using a special artificial intelligence tool, called VX1, during the procedure affects patient outcomes.
Evanston, IllinoisAges 21 years+ - NCT05996159Recruiting
Using very high power for short duration to treat atrial fibrillation
This study tests a new way to perform a common procedure (pulmonary vein isolation) for people with paroxysmal atrial fibrillation. Instead of using the standard amount of energy for a longer time, this method uses a very high amount of energy for a very short time. This might make the procedure faster and just as safe.
SeoulAges 19 years+ - NCT05411614Recruiting
Testing two heart procedures for atrial fibrillation in heart failure
This study compares two different ablation procedures (treatments that target heart rhythm triggers) for people with atrial fibrillation and reduced heart pumping. It aims to see which approach works best and is safest for improving your heart rhythm when you also have heart failure.
ChertseyAges 18 years+ - NCT05844501RecruitingPhase 4
Ondansetron before heart ablation for atrial fibrillation
This trial tests whether ondansetron can help people with atrial fibrillation (an abnormal heart rhythm) around the time of elective catheter ablation. It may improve the safety or effectiveness of the procedure by targeting a pathway involved in heart rhythm events.
Indianapolis, IndianaAges 18–100 - NCT05836987RecruitingPhase 3
Smartwatch-guided blood thinners for intermittent atrial fibrillation
This study tests whether using a smartwatch to monitor your heartbeat can safely guide when to take blood thinners. If you have intermittent atrial fibrillation, you may be able to avoid taking blood thinners when your heart rhythm is normal.
Phoenix, ArizonaAges 22–85 - NCT05794386Recruiting
Ablation plan guided by left-heart scar map for persistent atrial fibrillation
This study tests whether using a 3D heart “scar map” helps doctors choose a better catheter ablation strategy for people with persistent atrial fibrillation (AF). It may help reduce ongoing AF by targeting the scar area in the left atrium.
Seoul, Jongno-guAges 19 years+ - NCT05790707Recruiting
Ablation for persistent atrial fibrillation to help memory
This study checks whether a procedure called atrial fibrillation ablation can slow memory problems in people who already have mild cognitive impairment. Participants will be tested on thinking and memory before and after treatment to see if the procedure helps.
AngersAges 60–80 - NCT05723536Recruiting
Comparing two procedures for persistent atrial fibrillation
This study compares two ways to treat persistent atrial fibrillation (an irregular heartbeat that lasts for a long time). One method uses a catheter to treat the heart from the inside, and the other combines that with a small procedure on the outside of the heart. The goal is to see which approach works better for people whose symptoms haven't improved with medication.
BarcelonaAges 18–75 - NCT05557526Recruiting
Improving quality of life after atrial fibrillation ablation
This study aims to improve how patients feel in daily life after a procedure to treat atrial fibrillation (an irregular heartbeat). It focuses on whether better patient expectations and support can lead to a better quality of life after the procedure.
Düsseldorf, North Rhine-WestfaliaAges 18 years+ - NCT05504356Recruiting
Study to improve atrial fibrillation ablation and new therapies
This study looks at what results from atrial fibrillation ablation (a heart rhythm procedure) and newer related therapies. If you recently had the procedure—or are scheduled for it soon—you may use an app and website to share information that helps researchers compare outcomes and improve care.
San Francisco, CaliforniaAges 18 years+ - NCT05434819Recruiting
Ablation study during heart surgery for atrial fibrillation
This trial looks at whether a special heart rhythm treatment called “ablation” works well when done during certain heart operations. It may help reduce atrial fibrillation (AF) symptoms or future abnormal rhythm episodes for people who are already having surgery.
Hamilton, OntarioAges 18 years+ - NCT05366361Recruiting
Study of persistent atrial fibrillation during heart procedures
This study looks at what happens in the heart in people with persistent atrial fibrillation when they undergo an ablation or Maze surgery. It may help doctors better understand the condition and improve future care for people needing these procedures.
Stanford, CaliforniaAges 22–80 - NCT05293080RecruitingPhase 3
Early heart rhythm treatment to help prevent stroke
This trial tests an early treatment approach for people who had a recent ischemic stroke (a stroke caused by a blocked blood vessel) and have an irregular heart rhythm called atrial fibrillation (AF). It aims to lower the chance of having another stroke by treating AF as early as possible after the stroke.
HamburgAges 18 years+ - NCT05164107Recruiting
Test a new pulsed-field catheter procedure for atrial fibrillation
This trial tests a new pulsed-field device used during an atrial fibrillation (AF) catheter ablation, aiming to improve safety and effectiveness. It’s for people who have AF and are planning an AF ablation procedure.
PragueAges 18–75 - NCT05144503Recruiting
Test of a new catheter procedure for irregular heart rhythm
This study checks how safe and effective a special catheter procedure (SpherePVI) is for treating paroxysmal (comes and goes) or persistent atrial fibrillation. You may be considered if your atrial fibrillation keeps returning and you’ve already tried at least one medication but it didn’t work or you couldn’t tolerate it.
VilniusAges 18–75
Hear when a new Atrial Fibrillation Ablation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for atrial fibrillation ablation?
- Yes. Clin2 currently lists 291 recruiting atrial fibrillation ablation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation ablation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation ablation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.