Clinical trials
Atrial Fibrillation Ablation clinical trials
Below are recruiting atrial fibrillation ablation clinical trials, each written for real people, not researchers. We’re tracking 291 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06383975Recruiting
Two new treatments for AF that returned after first procedure
This trial tests two new treatments for persistent atrial fibrillation that came back after an initial procedure. One uses a targeted chemical injection, the other uses a special energy field to re-isolate the veins involved.
BrugesAges 18 years+ - NCT06499857RecruitingPhase 3
Semaglutide for atrial fibrillation and weight loss
This study tests whether a weekly injection of semaglutide (the same drug in Wegovy and Ozempic) can help people with atrial fibrillation lose weight and improve their heart condition. It's for people with AF who also have obesity, and may or may not plan to have a heart procedure called catheter ablation.
Phoenix, ArizonaAges 18–75 - NCT05617456Recruiting
Test new ablation technology for treating irregular heart rhythm
This study tests advanced technology to improve how atrial fibrillation (AFib) is treated with a heart ablation procedure. It may help patients who are already advised to have AFib ablation by seeing how well the approach works in real clinical practice.
PisaAges Any age - NCT07633548Enrolling by invitation
Simplified sedation protocol for heart rhythm ablation
This trial tests a streamlined sedation approach during pulsed-field ablation, a newer technique to treat irregular heartbeat (atrial fibrillation). Researchers want to confirm it's safe and practical.
CaenAges 18–80 - NCT06216769Recruiting
Pill-in-the-pocket blood thinners after AF ablation
This study tests a 'pill-in-the-pocket' approach for blood thinners after a catheter ablation for atrial fibrillation. Instead of taking a daily blood thinner, you may only take it when needed, which could reduce the risk of bleeding while still preventing strokes.
SeoulAges 19–89 - NCT07118046Recruiting
X-ray vs. 3D mapping for balloon AFib ablation
This study compares two ways to guide a balloon-based ablation procedure for atrial fibrillation: using only X-ray (fluoroscopy) versus using a 3D mapping system. The goal is to see if one method is safer or more effective.
Madrid, MadridAges 18 years+ - NCT07119528Recruiting
App-based care after heart ablation
This study tests whether a smartphone app can help people recover after a new type of heart ablation called pulse field ablation for atrial fibrillation. It aims to see if the app improves follow-up care and quality of life.
SeoulAges 19 years+ - NCT06833138Recruiting
Pacing vs medication for heart rate control in AF with heart failure
This trial tests whether a procedure that regulates your heart rhythm (pacing) works better than medication for people who have permanent atrial fibrillation, heart failure with a normal pumping strength, and were hospitalized for heart failure in the past year.
AalstAges 18 years+ - NCT07275697RecruitingPhase 4
Weight loss drug and heart ablation study for AFib
This trial tests whether a weight loss medication (semaglutide) given before and after a first-time heart ablation procedure for atrial fibrillation can improve outcomes. It is for people who are overweight or obese and have certain related health conditions.
StockholmAges 18 years+ - NCT02932007RecruitingPhase 2
Chloroquine to treat ongoing atrial fibrillation symptoms
This trial tests whether chloroquine can reduce symptoms in people with persistent atrial fibrillation (AF), an irregular heartbeat that lasts longer than a week. It will also closely monitor heart rhythm and safety, since the medicine can affect the heart and other organs.
Tampa, FloridaAges 18 years+ - NCT05826665Recruiting
Study of heart rhythm mapping during AF ablation
This is an observational study that looks at how a special heart mapping system may affect the procedure and outcomes for people having ablation for persistent atrial fibrillation (AF). It may help doctors better understand what works best and how procedures turn out.
Jonesboro, ArkansasAges 18–80 - NCT06801392Recruiting
Pulsed-field ablation for non-paroxysmal atrial fibrillation
This trial tests a new way to treat non-paroxysmal atrial fibrillation (AF) using a focused type of ablation (pulsed-field energy) on specific areas of the heart. It aims to see if targeting the left atrial wall and mitral isthmus can improve outcomes for people who have not had this procedure before.
PragueAges 18 years+ - NCT07210151Recruiting
Imaging Catheter for Heart Ablation Procedures
This study tests a new imaging catheter (VERAFEYE) to help doctors guide ablation procedures for atrial flutter or atrial fibrillation. It may lead to safer, more precise treatment of these heart rhythm problems.
SplitAges 18 years+ - NCT07405359Recruiting
Comparing ablation methods for persistent atrial fibrillation
This trial tests a newer, possibly safer way to treat persistent atrial fibrillation using pulsed field ablation. It compares standard vein isolation alone to adding extra ablation spots to improve success.
San Francisco, CaliforniaAges 18 years+ - NCT05116384Recruiting
Renal nerve ablation plus AF ablation for persistent AF
This study tests whether treating kidney-related nerves along with the usual AF (irregular heartbeat) catheter procedure works better than the usual procedure alone. It may help some people with persistent AF, but you must meet specific heart and kidney safety requirements.
Short Hills, New JerseyAges 18 years+ - NCT06747091Recruiting
Ablation study for people with persistent atrial fibrillation
This trial tests a catheter ablation procedure for people with persistent atrial fibrillation (a type of irregular heartbeat that lasts more than 7 days but less than a year). It aims to see if the procedure is safe and effective for restoring a normal heart rhythm.
Manhasset, New YorkAges 18–80 - NCT03168659Recruiting
Study of HeartLight during catheter ablation for irregular heartbeat
This study looks at the HeartLight device during a procedure to treat atrial fibrillation (an irregular heart rhythm) that comes and goes. It is meant for adults whose symptoms continue even after trying at least one anti-arrhythmia medicine.
Tucson, ArizonaAges 18 years+ - NCT07175428RecruitingPhase 2
Safety of a New Blood Thinner in AFib Patients
This study tests the safety of a new blood thinner for people with atrial fibrillation (AFib) who need long-term stroke prevention. If you qualify, the study will compare this medication to standard anticoagulation therapy.
Dothan, AlabamaAges 18 years+ - NCT04947657Recruiting
Atrial fibrillation blood and heart scan pilot during ablation
This study looks at blood-related “clotting” signs and heart scan results in people with atrial fibrillation (AF) who are getting a catheter ablation. It may help doctors better understand AF and choose treatments more precisely.
New Orleans, LouisianaAges 18–120 - NCT05174052RecruitingPhase 3
Dapagliflozin for heart rhythm problems in diabetes
This trial studies dapagliflozin, a diabetes medicine, to see if it can help people with paroxysmal atrial fibrillation (irregular heart rhythm). If you have both diabetes and this type of AF, the study may offer a chance to improve your heart rhythm and outcomes.
Oklahoma City, OklahomaAges 18–85 - NCT05326828Recruiting
Implant monitor to find hidden atrial fibrillation after heart injury
This study tests whether an implantable heart rhythm monitor can detect atrial fibrillation (an irregular heartbeat) in people who had a type of heart attack with non-obstructed arteries. The goal is to find a possible reason for the event so doctors can treat it appropriately.
BernAges 18–85 - NCT05841615Recruiting
Atrial fibrillation and high blood pressure ablation plus kidney nerve treatment
This trial tests whether treating atrial fibrillation with a catheter procedure plus treating high blood pressure through kidney nerve treatment works better together. It may help control rhythm and blood pressure, but you must meet several heart, kidney-artery, and safety requirements.
Xiamen, FujianAges 18–75 - NCT07085650Recruiting
Atrial Fibrillation Ablation Study
This study is for people with atrial fibrillation who are planning to have a catheter ablation procedure. It will look at how well the heart works after the procedure and how to prevent future events.
Shenyang, LiaoningAges 18 years+ - NCT06578793Recruiting
Catheter plus vein ablation for atrial fibrillation with heart failure
This trial tests whether adding a vein ablation to standard catheter ablation helps people with persistent atrial fibrillation and heart failure. It aims to find the best treatment to improve heart function and reduce symptoms.
Changsha, HunanAges 18–80
Hear when a new Atrial Fibrillation Ablation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for atrial fibrillation ablation?
- Yes. Clin2 currently lists 291 recruiting atrial fibrillation ablation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation ablation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation ablation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.