Clinical trials
Atrial Fibrillation and Flutter clinical trials
Below are recruiting atrial fibrillation and flutter clinical trials, each written for real people, not researchers. We’re tracking 93 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05106270Recruiting
Atrial pressure changes around a heart procedure for atrial fibrillation
This trial studies how changing pressure in the heart’s upper chamber before and after a combined heart procedure affects outcomes in people with atrial fibrillation. It may help guide safer, more effective care for patients who need left atrial appendage closure (a way to reduce stroke risk).
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06061757Recruiting
Combining 4D-ICE and TEE imaging for heart closure
This trial tests a new imaging method (4D-ICE) used alongside a standard ultrasound (TEE) during a heart procedure to close the left atrial appendage, a small pouch in the heart where clots can form in people with atrial fibrillation. The goal is to see if the new method makes the procedure safer and more precise.
Overland Park, KansasAges 18–80 - NCT06402851RecruitingPhase 4
Blood thinner or none for atrial fibrillation with dialysis
This trial compares two types of blood thinners (vitamin K antagonists and factor Xa inhibitors) versus no blood thinner in people with atrial fibrillation who are on dialysis or have very advanced kidney disease. It aims to see which option is safest and most effective for preventing strokes and bleeds.
Salvador, Estado de BahiaAges 18 years+ - NCT04449523Recruiting
Check for hidden heart rhythm problems after silent brain strokes
This study looks at how often “silent” atrial fibrillation—an irregular heart rhythm that can be symptom-free—happens in people who have silent brain stroke spots on MRI. If it finds a link, it may help identify which patients might benefit from closer heart monitoring or prevention steps.
GrazAges 50 years+ - NCT06715449RecruitingPhase 2/Phase 3
Testing empagliflozin after a stroke with unknown cause
This trial tests if a diabetes drug called empagliflozin can help the heart's left atrium work better in people who have had a stroke with no known cause. You may join if you are getting a heart monitor device implanted to look for hidden irregular heartbeats.
Cambridge, CambridgeshireAges 18 years+ - NCT06199180Recruiting
Comparing two ablation methods for repeat atrial fibrillation treatment
This trial tests a newer type of energy (pulsed field ablation) against the standard heat-based method (radiofrequency) for people who have already had one ablation and now have atrial fibrillation again. The goal is to see which works better for keeping your heart in a normal rhythm.
GroningenAges 18–80 - NCT06800781Recruiting
Chest tube duration to prevent afib after heart surgery
This trial tests if leaving a chest tube in a little longer after heart surgery can lower the chance of developing atrial fibrillation (an irregular heart rhythm). It's for people having certain planned heart surgeries who have not had this rhythm problem before.
LundAges 18 years+ - NCT05841056RecruitingPhase 3
Short amiodarone treatment to prevent new heart rhythm after surgery
This trial studies whether a short course of amiodarone started right after heart surgery can reduce problems from new-onset atrial fibrillation (a common fast heart rhythm) or flutter. It may help some patients avoid ongoing rhythm issues and improve recovery soon after discharge.
Hamilton, OntarioAges 18 years+ - NCT07295769Recruiting
Detecting hidden atrial fibrillation after stroke of unknown cause
This study uses a small patch (M.E.M.O. Patch) to continuously monitor your heart rhythm for hidden atrial fibrillation, a treatable cause of stroke. The goal is to see if the patch can find irregular heartbeats that standard tests might miss.
Seoul, Songpa-guAges 19 years+ - NCT03907046RecruitingPhase 3
Blood thinner study to prevent stroke after brain bleed
This Phase 3 study tests whether a blood thinner (apixaban) can help prevent another stroke and support recovery after you’ve had a brain bleed. You would be assigned to a treatment group, and the study checks safety and whether strokes can be reduced without causing dangerous bleeding.
Birmingham, AlabamaAges 18 years+ - NCT07429214Recruiting
Study of a new catheter for atrial fibrillation ablation
This trial tests a new catheter system to treat atrial fibrillation (AF) by creating small scars in the heart to block faulty signals. It may help people with symptoms that continue despite medication and who are scheduled for a standard ablation procedure.
AalstAges 18–75 - NCT04964765Recruiting
3D heart mapping after early irregular heartbeat after surgery
This study uses 3D heart mapping to understand a specific kind of irregular heartbeat that can happen soon after cardiac surgery. It may help doctors better recognize what’s happening in the heart during the early recovery period.
Sankt PöltenAges 18 years+ - NCT05717725RecruitingPhase 3
Pulsed heart ablation vs fake procedure for irregular heartbeat
This trial tests whether pulsed-field ablation (a targeted treatment meant to stop abnormal heart signals) works better than a sham, or “placebo,” ablation. It is for certain people with atrial fibrillation (AF) to see if symptoms and heart rhythm outcomes improve.
PragueAges 18 years+ - NCT05826665Recruiting
Study of heart rhythm mapping during AF ablation
This is an observational study that looks at how a special heart mapping system may affect the procedure and outcomes for people having ablation for persistent atrial fibrillation (AF). It may help doctors better understand what works best and how procedures turn out.
Jonesboro, ArkansasAges 18–80 - NCT06061120Recruiting
Heart rhythm study for ablation patients
This study uses a special ECG to better tell apart different types of fast heart rhythms in people scheduled for a procedure called ablation. The goal is to improve diagnosis and treatment for conditions like atrial fibrillation and other supraventricular tachycardias.
Aachen, North Rhine-WestphaliaAges 18 years+ - NCT06953726RecruitingPhase 4
Comparing apixaban and rivaroxaban for atrial fibrillation
This study compares two common blood thinners, apixaban and rivaroxaban, in veterans with atrial fibrillation or flutter to see which one is safer and works better. If you are already taking one of these medicines, you may be able to join.
Miami, FloridaAges 65 years+ - NCT07129564Recruiting
Stepwise treatment for persistent atrial fibrillation
This study tests a stepwise treatment plan for people with persistent atrial fibrillation (a long-lasting irregular heartbeat) who also have an enlarged left atrium. It aims to see if a medication called amiodarone plus a cardioversion procedure can help restore normal rhythm.
ChongqingAges 18–70 - NCT07236619Recruiting
A new heart procedure for atrial fibrillation
This study tests a new catheter that uses pulsed field energy to isolate the veins in your heart that trigger atrial fibrillation. The goal is to see how long the effects last, and you would need to have a repeat procedure about 2–3 months after the first one.
Rotterdam, South HollandAges 18–80 - NCT07278089Recruiting
AF screening for people with heart changes on echo
This trial checks if people with certain heart conditions seen on an echo (like an enlarged heart or stiff heart muscle) have undetected atrial fibrillation (AF). It aims to find AF early so it can be treated to prevent strokes.
TaipeiAges 20 years+ - NCT07521800Recruiting
Remote Heart Monitoring After Aortic Valve Replacement
This study tests whether monitoring your heart rhythm at home using a portable ECG device after your aortic valve replacement procedure (TAVI) helps catch problems early. Researchers want to see if remote monitoring is safe and helpful for patients recovering from this procedure.
TurinAges 18 years+ - NCT05236556Enrolling by invitation
Tracking how providers use oral blood thinners for AF
This study looks at how often and how well doctors use oral blood-thinner medicines for people with atrial fibrillation (AF) or atrial flutter (a related heart rhythm problem). It aims to see whether “provider profiling” (using clinic patterns to guide improvements) can support safer, more consistent use of these medicines.
Jacksonville, FloridaAges 18 years+
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Common questions
- Are there clinical trials for atrial fibrillation and flutter?
- Yes. Clin2 currently lists 93 recruiting atrial fibrillation and flutter studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation and flutter trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation and flutter trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.