Clinical trials · California
Atrial fibrillation clinical trials in California
We’re tracking 40 recruiting atrial fibrillation studies with a site in California — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07175428RecruitingPhase 2
Safety of a New Blood Thinner in AFib Patients
This study tests the safety of a new blood thinner for people with atrial fibrillation (AFib) who need long-term stroke prevention. If you qualify, the study will compare this medication to standard anticoagulation therapy.
Covina, CaliforniaAges 18 years+ - NCT03968393RecruitingPhase 4
Blood thinner to prevent stroke after stress-related irregular heartbeats
This trial tests whether taking a blood thinner can lower the risk of stroke in people who had atrial fibrillation (an irregular heartbeat) that happened temporarily around a stressful illness or surgery. It looks especially at people at higher risk for stroke after that episode.
Los Angeles, CaliforniaAges 55 years+ - NCT07430956RecruitingPhase 3
Stroke prevention in atrial fibrillation without standard blood thinners
This trial tests a new medication to prevent strokes and blood clots in people with atrial fibrillation (an irregular heartbeat) who cannot safely take standard blood thinners. The drug works by blocking a different clotting factor, which may lower bleeding risks.
Huntington Beach, CaliforniaAges 18 years+ - NCT07527299Recruiting
Varipulse catheter study for persistent atrial fibrillation
This study tests a new catheter to treat persistent atrial fibrillation (a type of irregular heartbeat lasting more than 7 days but less than a year). It aims to isolate the pulmonary veins and superior vena cava to restore normal rhythm. Some participants may also receive a left atrial appendage occlusion device if needed.
Birmingham, AlabamaAges 18–80 - NCT05712200RecruitingPhase 3
Abelacimab for atrial fibrillation when blood thinners aren’t suitable
This Phase 3 study tests whether abelacimab can prevent stroke and other blood-clot problems in people with atrial fibrillation (or atrial flutter) who cannot safely take usual mouth blood thinners. It also looks at safety, especially bleeding risk.
Huntington Beach, CaliforniaAges 65 years+ - NCT06735534Recruiting
Repeat ablation for persistent atrial fibrillation with pulsed field
This trial tests a newer type of ablation (pulsed field ablation) for people with persistent atrial fibrillation who have already had one ablation. The goal is to see if it can fix the heart rhythm problem again.
Los Angeles, CaliforniaAges 18 years+ - NCT07278869Recruiting
Study of Append system for atrial fibrillation patients
This trial tests a new device, the Append System, to close off the left atrial appendage (a small pouch in the heart) in people with atrial fibrillation. The goal is to reduce stroke risk without needing long-term blood thinners.
Los Angeles, CaliforniaAges 18 years+ - NCT05963698Recruiting
Closing off a heart pouch to prevent stroke
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
Pasadena, CaliforniaAges 18 years+ - NCT07308847Recruiting
Study of a new catheter system for treating atrial fibrillation
This trial tests a new catheter and mapping system designed to treat paroxysmal atrial fibrillation (AF), which is a type of irregular heartbeat that comes and goes. If you have this condition, the study aims to see how well the new system works with a minimally invasive procedure.
La Jolla, CaliforniaAges 18–80 - NCT06335082Enrolling by invitation
Study of Farapulse ablation for atrial fibrillation
This registry is collecting information to see how well the Farapulse PFA system works and how safe it is for treating atrial fibrillation (AF), a common heart rhythm problem. If you are scheduled to have an ablation for AF with this system, this study will follow your progress.
Los Angeles, CaliforniaAges 18 years+ - NCT03907046RecruitingPhase 3
Blood thinner study to prevent stroke after brain bleed
This Phase 3 study tests whether a blood thinner (apixaban) can help prevent another stroke and support recovery after you’ve had a brain bleed. You would be assigned to a treatment group, and the study checks safety and whether strokes can be reduced without causing dangerous bleeding.
Castro Valley, CaliforniaAges 18 years+ - NCT07405359Recruiting
Comparing ablation methods for persistent atrial fibrillation
This trial tests a newer, possibly safer way to treat persistent atrial fibrillation using pulsed field ablation. It compares standard vein isolation alone to adding extra ablation spots to improve success.
San Francisco, CaliforniaAges 18 years+ - NCT06392932Recruiting
Esophageal temperature monitoring during heart ablation
This study tests a new way to monitor the temperature in your esophagus during a standard heart ablation procedure for atrial fibrillation. The goal is to see if the new catheter (Q-DOT Micro) safely heats the heart tissue without harming the esophagus.
Los Angeles, CaliforniaAges 18 years+ - NCT05111015Recruiting
Ablation tracking study for people with atrial fibrillation
This study tracks results after a heart ablation procedure used to treat atrial fibrillation (an irregular heart rhythm). You may be asked to help by consenting and following the study plan so the researchers can better understand what happens after ablations.
St. Helena, CaliforniaAges 18 years+ - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT07775976Enrolling by invitation
Whole-heart checkup with a wearable heart monitor
This study looks at how well a wearable heart monitor and special software can check the health of your whole heart and assess your risk of future heart problems. It may help doctors create more personalized care plans.
Pasadena, CaliforniaAges 18 years+
Atrial fibrillation trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting atrial fibrillation studies listed above.
- Cedars-Sinai Medical Center · 5 studies
- Cardiology Associates Medical Group · 2 studies
- Interventional Cardiology Medical Group · 2 studies
- Mission Cardiovascular Research Institute · 2 studies
- National Institute of California Heart and Vein Specialists · 2 studies
- Profound Research LLC · 2 studies
- Stanford University · 2 studies
- Adventist Health St Helena
What taking part in a atrial fibrillation study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Atrial fibrillation trials in other states
Common questions
- Are there atrial fibrillation clinical trials in California?
- Yes. We're currently tracking 40 recruiting atrial fibrillation studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a atrial fibrillation study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New atrial fibrillation studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.