Clinical trials · Massachusetts
Atrial fibrillation clinical trials in Massachusetts
We’re tracking 26 recruiting atrial fibrillation studies with a site in Massachusetts — including Early Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Massachusetts
- NCT07625215RecruitingPhase 2
Testing BAY 3670549 for Recent-Onset Atrial Fibrillation
This study tests a new drug called BAY 3670549 to see if it can help convert atrial fibrillation (an irregular heartbeat) back to normal rhythm. You'll receive the study drug or a placebo along with a procedure to restore your heart's normal rhythm, and researchers will monitor how well it works and how safe it is.
Boston, MassachusettsAges 18–85 - NCT07298473Recruiting
Redo ablation for recurrent atrial fibrillation with Sphere-9 catheter
This trial tests a new catheter and system for people who have had one previous ablation for atrial fibrillation but still have symptoms. It aims to see if a repeat procedure can safely and effectively treat recurrent episodes.
Boston, MassachusettsAges 18 years+ - NCT06615596RecruitingEarly Phase 1
Stopping blood thinners after successful atrial fibrillation ablation
This trial tests whether it is safe to stop taking blood thinners (anticoagulants) after a successful ablation procedure for atrial fibrillation. If you have had no AF for 3 months after your first ablation, you may be able to stop these medications, reducing your risk of bleeding.
Boston, MassachusettsAges 18 years+ - NCT05997914Enrolling by invitation
Storytelling to reduce stroke risk in African Americans with atrial fibrillation
This study tests whether a storytelling program can help African American patients with atrial fibrillation start taking blood thinners as recommended by their doctor. The goal is to reduce stroke risk and improve health outcomes.
Worcester, MassachusettsAges 18 years+ - NCT05836987RecruitingPhase 3
Smartwatch-guided blood thinners for intermittent atrial fibrillation
This study tests whether using a smartwatch to monitor your heartbeat can safely guide when to take blood thinners. If you have intermittent atrial fibrillation, you may be able to avoid taking blood thinners when your heart rhythm is normal.
Boston, MassachusettsAges 22–85 - NCT06324201Recruiting
Long-term safety of a new ablation system for paroxysmal AF
This study tests a new system (QDOT MICRO and VISITAG SURPOINT) used during a catheter ablation procedure to treat atrial fibrillation (AF). It aims to see how safe and effective it is over the long term for people whose AF comes and goes and hasn't been controlled by medication.
Boston, MassachusettsAges 18 years+ - NCT04088071Recruiting
Ablation for heart rhythm problems using a specific technology
This study looks at how well catheter ablation works for treating certain heart rhythm disorders (like atrial fibrillation or ventricular arrhythmias) using a specific brand of catheters. The aim is to gather real-world data to better understand the procedure's outcomes.
Boston, MassachusettsAges 18 years+ - NCT04045665RecruitingPhase 3
Blood thinner vs usual care for new heart rhythm after bypass surgery
This trial tests whether using a blood thinner in people with new, temporary atrial fibrillation after CABG (heart bypass surgery) can reduce harmful outcomes compared with standard treatment. It may help prevent stroke or other complications if your rhythm problem fits the trial’s timing and risk profile.
Springfield, MassachusettsAges 18 years+ - NCT03546374Recruiting
Stop a common heart rhythm with surgery add-on therapy
This study looks at whether an added heart device approach around the time of planned open-heart surgery can help treat non-paroxysmal atrial fibrillation (AF), a long-lasting irregular heartbeat. It may help lower ongoing AF burden in people who also need non-emergency heart surgery.
Boston, MassachusettsAges 18 years+ - NCT07173998Recruiting
Quality of life after heart surgery with irregular heartbeat
This study looks at quality of life in people who develop atrial fibrillation (an irregular heartbeat) after heart surgery. Researchers will ask you to fill out surveys to understand how this condition affects your daily life.
Boston, MassachusettsAges 18–100 - NCT07175428RecruitingPhase 2
Safety of a New Blood Thinner in AFib Patients
This study tests the safety of a new blood thinner for people with atrial fibrillation (AFib) who need long-term stroke prevention. If you qualify, the study will compare this medication to standard anticoagulation therapy.
Boston, MassachusettsAges 18 years+ - NCT05723926Recruiting
Carotid implants to help prevent stroke repeat in atrial fibrillation
This trial tests whether placing a carotid implant can reduce the chance of having another stroke in people with atrial fibrillation who are already taking blood thinners. It aims to prevent stroke recurrence while you continue prescribed anticoagulation.
Boston, MassachusettsAges 18 years+ - NCT04880265Recruiting
Study heart rhythm changes after open-heart surgery
This study looks at how often and how long an irregular heartbeat (atrial fibrillation) happens after planned open-heart surgery. It aims to better understand the “burden” of this rhythm problem, which could help improve care for future patients.
Boston, MassachusettsAges 20–90 - NCT07468123Enrolling by invitation
Estimating Atrial Fibrillation Risk With a Handheld ECG
This trial uses a simple, handheld ECG device (like a small card) to check your risk for atrial fibrillation, a common irregular heartbeat. You'll record short heart tracings at home, and the study team will review them to find hidden risk factors.
Boston, MassachusettsAges 18–90 - NCT05712200RecruitingPhase 3
Abelacimab for atrial fibrillation when blood thinners aren’t suitable
This Phase 3 study tests whether abelacimab can prevent stroke and other blood-clot problems in people with atrial fibrillation (or atrial flutter) who cannot safely take usual mouth blood thinners. It also looks at safety, especially bleeding risk.
Boston, MassachusettsAges 65 years+ - NCT05963698Recruiting
Closing off a heart pouch to prevent stroke
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
Burlington, MassachusettsAges 18 years+ - NCT01258231Recruiting
Genetic test to predict risks after heart surgery
This study looks for genetic (DNA) clues that may help predict side effects or complications after heart surgery. If you join, your genome information may be used to understand who is at higher risk and why.
Boston, MassachusettsAges 20–90 - NCT06957366Recruiting
Managing Blood Thinners Before High-Risk Surgery
This study looks at how to safely manage your blood thinner (DOAC) around the time of a planned, high-bleed-risk surgery or procedure involving a spinal needle. The goal is to find the best way to stop and restart your medication to prevent bleeding and clotting problems.
Boston, MassachusettsAges 18 years+ - NCT06953726RecruitingPhase 4
Comparing apixaban and rivaroxaban for atrial fibrillation
This study compares two blood thinners, apixaban and rivaroxaban, to see which is safer and works better for veterans with atrial fibrillation (irregular heartbeat). If you're already taking one of these, the study will assign you to one of them.
Boston, MassachusettsAges 22 years+ - NCT06578104Recruiting
Pulsed AF Study: PulseSelect Catheter for Afib
This study tests a new way to treat atrial fibrillation (Afib) using a special catheter system called PulseSelect that delivers short bursts of energy to create scar tissue in the heart. It is for people whose Afib comes and goes or stays for a while but not more than a year, and who have not had a prior ablation procedure or have a pacemaker or defibrillator.
Fall River, MassachusettsAges 18 years+ - NCT06335082Enrolling by invitation
Study of Farapulse ablation for atrial fibrillation
This registry is collecting information to see how well the Farapulse PFA system works and how safe it is for treating atrial fibrillation (AF), a common heart rhythm problem. If you are scheduled to have an ablation for AF with this system, this study will follow your progress.
Boston, MassachusettsAges 18 years+ - NCT06099730Recruiting
Pulsed field ablation for atrial fibrillation
This trial tests a new method called pulsed field ablation to treat atrial fibrillation (AF), a type of irregular heartbeat. It aims to safely stop AF episodes by targeting specific areas in the heart, and may help people with paroxysmal (coming and going) or persistent AF who haven't had this procedure before.
Boston, MassachusettsAges 18–80 - NCT05236556Enrolling by invitation
Tracking how providers use oral blood thinners for AF
This study looks at how often and how well doctors use oral blood-thinner medicines for people with atrial fibrillation (AF) or atrial flutter (a related heart rhythm problem). It aims to see whether “provider profiling” (using clinic patterns to guide improvements) can support safer, more consistent use of these medicines.
Worcester, MassachusettsAges 18 years+ - NCT03907046RecruitingPhase 3
Blood thinner study to prevent stroke after brain bleed
This Phase 3 study tests whether a blood thinner (apixaban) can help prevent another stroke and support recovery after you’ve had a brain bleed. You would be assigned to a treatment group, and the study checks safety and whether strokes can be reduced without causing dangerous bleeding.
Burlington, MassachusettsAges 18 years+
Atrial fibrillation trials by city in Massachusetts
Where these studies are running in Massachusetts
Institutions with a site for the recruiting atrial fibrillation studies listed above.
- Brigham and Women's Hospital · 6 studies
- Massachusetts General Hospital · 6 studies
- Beth Israel Deaconess Medical Center · 4 studies
- Boston Medical Center · 3 studies
- Mass General Brigham · 3 studies
- UMass Chan Medical School · 3 studies
- Lahey Hospital and Medical Center · 2 studies
- Tufts Medical Center · 2 studies
What taking part in a atrial fibrillation study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Atrial fibrillation trials in other states
Common questions
- Are there atrial fibrillation clinical trials in Massachusetts?
- Yes. We're currently tracking 26 recruiting atrial fibrillation studies with a site in Massachusetts, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a atrial fibrillation study in Massachusetts?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Massachusetts to take part?
- Not necessarily. These studies have a site in Massachusetts, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a atrial fibrillation trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New atrial fibrillation studies open in Massachusetts regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.