Clinical trials
Bipolar Disorder I or II clinical trials
Below are recruiting bipolar disorder i or ii clinical trials, each written for real people, not researchers. We’re tracking 2,379 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02966665RecruitingPhase 1
Testing blood vessel function in people of different health conditions
This early study measures how well your blood vessels work using tests that may include MRI. It compares healthy people with people who have conditions like COPD, pulmonary arterial hypertension, heart failure, or high blood pressure, to better understand “vascular function” in health and disease.
Salt Lake City, UtahAges 18 years+ - NCT03423680RecruitingPhase 3
Aripiprazole added to mood stabilizers for bipolar depression
This trial tests whether adding aripiprazole (Abilify) to a mood stabilizer helps people with bipolar disorder who are currently in a major depressive episode. It may help improve depressive symptoms compared with the mood stabilizer alone.
SeoulAges 19–70 - NCT03522545RecruitingPhase 1
Stem cell add-on for hard-to-treat bipolar depression
This Phase 1 study tests whether adding allogeneic (donor) stem cells to standard care is safe and may help adults with bipolar depression that has not improved with usual treatments. It mainly targets people with more severe symptoms and certain blood inflammation levels.
Houston, TexasAges 18–65 - NCT03594630RecruitingEarly Phase 1
Watchful waiting then chemotherapy before surgery for rectal cancer
This trial studies whether a period of active surveillance (watching closely) and chemotherapy before surgery can improve outcomes for people with stage II–III rectal cancer. You would also receive standard chemo-radiation if you qualify, then proceed to surgery.
Houston, TexasAges 18 years+ - NCT03601702Recruiting
EmboTrap device for large stroke blockages
This trial studies whether a specific clot-removal device (EmboTrap II) works well for acute stroke caused by a large artery blockage. It may help restore blood flow faster in people who have certain scan patterns and can be treated within 12 hours.
MilanAges 18 years+ - NCT03669315RecruitingPhase 3
Theta burst brain stimulation for gambling disorder
This Phase 3 trial tests whether theta burst stimulation (a type of non-invasive brain treatment) can improve control over gambling urges and behaviors. It is meant for adults with a confirmed diagnosis of gambling disorder and no major complicating mental health or medical issues.
FlorenceAges 18–65 - NCT03859297Recruiting
Testing how rumination changes in depressed teens
This study looks at what changes in “rumination” (repetitive worrying/thinking about negative thoughts) in teens with depression, and how those changes relate to recovery. It’s for ages 14–17 who have had major depression and meet specific screening and medical rules.
Columbus, OhioAges 14–17 - NCT03994510Recruiting
Study of shame in borderline personality disorder
This study looks at how people with borderline personality disorder experience shame and how that relates to symptoms and behavior. The goal is to better understand shame so future treatments can be more targeted.
Montpellier, HéraultAges 18 years+ - NCT04089631RecruitingPhase 3
Blood test guides extra treatment after stage II colon cancer surgery
This study uses a blood test called ctDNA to decide whether you need extra (adjuvant) chemotherapy after stage II colon or certain stage II rectal cancer surgery. It may help avoid unnecessary treatment or better target people who still have signs of cancer after surgery.
Dresden, SaxonyAges 18 years+ - NCT04152993RecruitingEarly Phase 1
Brain stimulator study for chronic, hard-to-treat PTSD
This early-phase study tests a responsive brain stimulation device to help people with chronic PTSD who have not improved with standard treatments. You would be closely followed for years, with regular assessments and device setting changes to see if symptoms improve.
Los Angeles, CaliforniaAges 25–60 - NCT04201210RecruitingPhase 2
Stem cell transplant study for young people with severe sickle cell
This Phase 2 study tests a type of stem cell transplant that uses donor immune cells that have been specially “tweaked” to help treat sickle cell disease. It may help prevent serious sickle cell complications, but it requires careful matching and screening of organs and pregnancy status.
ViennaAges 2–35 - NCT04221997RecruitingPhase 4
Sertraline study for anxious children and teens
This trial tests whether sertraline (an anti-anxiety medicine) helps children and teens with generalized, separation, and/or social anxiety disorders. It also includes healthy children/teens for comparison so researchers can better understand safety and symptoms over time.
Cincinnati, OhioAges 8–17 - NCT04414878Recruiting
Transcatheter aortic valve replacement for older, high-risk patients
This trial tests a new heart valve replacement done through a catheter (not open-heart surgery) in older adults with severe aortic valve narrowing. It’s mainly for people who are high-risk or not good candidates for standard surgery, to see if the new valve improves outcomes.
Beijing, Beijing MunicipalityAges 70 years+ - NCT04426448Recruiting
Test a short PTSD talk therapy for people in Botswana
This study tests a brief counseling intervention for people who have PTSD symptoms. It aims to see if a short, structured approach can help reduce PTSD symptoms for adults in Botswana.
LobatseAges 18 years+ - NCT04528355Recruiting
Study of hospital data after stem cell transplant for non-cancer illness
This study collects medical information from people with certain non-cancer conditions who receive a stem cell transplant. It may help doctors better understand transplant outcomes and care, since the study focuses on data collection rather than adding new treatment.
Pittsburgh, PennsylvaniaAges 2 months–60 years - NCT04532190Recruiting
Testing options beyond standard ADHD treatment
This study looks for alternatives to standard treatment for attention-deficit/hyperactivity disorder (ADHD). It may help by testing a different approach for people who meet specific age, language, and health requirements.
Calgary, AlbertaAges 9–15 - NCT04539951RecruitingPhase 2
Trial for newly treated obsessive-compulsive disorder
This phase 2 study tests an OCD treatment strategy for people who have not yet had OCD medications or recent OCD therapy. It aims to reduce OCD symptoms, especially for those with moderate-to-severe symptom levels.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT04540107RecruitingPhase 1
MRI scan study to characterize lower-grade brain tumors
This Phase 1 study uses special MRI scans (including a form of MR spectroscopy) to better understand lower-grade gliomas. It is designed to test how well the imaging can “characterize” the tumor and to improve understanding for treatment planning.
San Francisco, CaliforniaAges 18 years+ - NCT04558541Recruiting
Speech and grammar training study for kids with language disorder
This study looks at how children with developmental language disorder understand and produce parts of speech, especially verb endings and grammar patterns. It may help researchers develop better ways to support communication in kids who struggle with language.
Tucson, ArizonaAges 4–8 - NCT04569448RecruitingPhase 3
Brexpiprazole for bipolar depression that won’t improve
This Phase 3 study tests whether brexpiprazole can help treat bipolar depression that has not responded to previous treatments. It compares the study medicine to a placebo (inactive pill) for people with bipolar I or II depression.
Hamilton, OntarioAges 18–75 - NCT04587791RecruitingEarly Phase 1
Cannabidiol (CBD) for opioid use disorder and chronic pain
This early study tests whether CBD can reduce symptoms of chronic pain in people receiving opioid maintenance treatment for opioid use disorder. It also looks at safety and whether CBD can be added without causing major problems.
West Haven, ConnecticutAges 18–70 - NCT04602325Recruiting
Blood and brain injury biomarker study for inherited metabolic disorders
This trial studies blood and other measurable signs (biomarkers) that may reflect brain injury after certain inherited metabolic conditions. Results may help doctors better detect and understand brain effects from these illnesses, especially episodes that affect the brain.
Washington D.C., District of ColumbiaAges 7–18 - NCT04602754RecruitingPhase 3
Oral treatment test for type 2 diabetes and bad cholesterol
This Phase 3 study tests whether Berlim 25/20 can improve blood sugar control and cholesterol (LDL) in adults with type 2 diabetes who haven’t met targets despite prior lifestyle guidance and treatment. It also looks at safety, including effects on the heart and medication-related side effects.
Campinas, São PauloAges 18–85 - NCT04637620RecruitingPhase 2
NMDA-based treatment study for major depression
This Phase 2 trial tests whether an NMDA-targeted treatment can improve symptoms of major depressive disorder (MDD). You may be able to join if your depression diagnosis and symptom score fit, and you meet several safety and study-following requirements.
TaichungAges 18–55
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Common questions
- Are there clinical trials for bipolar disorder i or ii?
- Yes. Clin2 currently lists 2,379 recruiting bipolar disorder i or ii studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bipolar disorder i or ii trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bipolar disorder i or ii trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.