Clinical trials
Bipolar Disorder I or II clinical trials
Below are recruiting bipolar disorder i or ii clinical trials, each written for real people, not researchers. We’re tracking 2,381 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05999240RecruitingPhase 2
Pimavanserin for rigid-compulsive symptoms in autism
This trial tests if the drug pimavanserin can help reduce rigid or repetitive behaviors in people with autism spectrum disorder. It may be an option if you or your child struggle with these symptoms and want to try a new treatment.
Lawrence, KansasAges 12–40 - NCT06005103Recruiting
Testing a headband that sends brain pulses for depression
This study tests a new headband that sends gentle electrical pulses to the brain (T-PEMF) to lift depression. You might join if you have moderate to severe depression and don't have certain other conditions or implants.
Frederiksberg, Capital RegionAges 18–65 - NCT06017765Recruiting
Mindfulness for grief after losing a loved one
This study tests whether a mindfulness program can help adults cope with intense grief after the loss of a loved one. If you have been diagnosed with Prolonged Grief Disorder and are not in other grief treatment, this may be an option for you.
Caen, CalvadosAges 18–60 - NCT06017713Recruiting
Brain stimulation plus exposure for stubborn OCD
This trial tests whether a gentle brain stimulation (tDCS) combined with facing your fears can help people with hard-to-treat OCD. If you've tried multiple treatments without relief, this study may offer a new option.
PoitiersAges 18–70 - NCT06018272Recruiting
Mentalization therapy for borderline personality disorder
This trial compares a therapy called mentalization-based treatment with other proven therapies for people with borderline personality disorder. It aims to find out which approach works better for reducing self-harm and suicidal behaviors.
BerlinAges 18–65 - NCT06022913Recruiting
Behavioral activation therapy for bipolar depression
This trial tests a therapy called behavioral activation to help people with bipolar depression feel better. The therapy focuses on increasing positive activities and routines to improve mood.
ReykjavikAges 18 years+ - NCT06066983Recruiting
Treating anxiety in children with autism (DINO RCT)
This study tests a therapy to help young children with autism who also have anxiety. The goal is to reduce anxious behaviors and improve daily life.
Baltimore, MarylandAges 4–6 - NCT06072898RecruitingPhase 2
Psilocybin brain imaging trial for depression
This study tests whether a single dose of psilocybin (a psychedelic compound) can help treat depression by looking at brain changes on MRI. It is designed for people with moderate-to-severe depression who have not responded well to other treatments.
Toronto, OntarioAges 18–64 - NCT06088121Recruiting
TMS with cognitive training for mild Alzheimer's dementia
This study tests a combination of brain stimulation (TMS) and cognitive training to improve memory and thinking in people with mild Alzheimer's. It may help if you are already on a stable dose of a donepezil-type medication and have a confirmed Alzheimer's diagnosis.
Incheon, Bupyeong 6(yuk)-dong, Bupyeong-guAges 60–85 - NCT06088732RecruitingPhase 1/Phase 2
Exercise and ibuprofen for bipolar depression
This study tests whether acute exercise and ibuprofen can improve symptoms of bipolar depression by studying their effects on the immune system and brain circuits. It may help if you are currently in a depressive episode and can do moderate physical activity.
Tulsa, OklahomaAges 18–55 - NCT06096740Recruiting
Talking therapy for PTSD and its effects on the brain
This study looks at how a specific type of talk therapy affects the way your brain processes rewards. You'd join a group that either starts therapy right away or waits a bit before starting. Your brain activity will be scanned with an MRI to see changes.
Austin, TexasAges 18–65 - NCT06105853Recruiting
Stress and brain activity in alcohol use disorder
This study looks at how people with alcohol use disorder respond to stress and what happens in the brain. You'll use a smartphone and may have an MRI scan to understand your stress responses.
Mannheim, Baden-WurttembergAges 18–65 - NCT06115603RecruitingPhase 2
Testing CBG for ADHD symptoms
This study tests whether a non-psychoactive compound from hemp called CBG (cannabigerol) can help with ADHD symptoms. You will take CBG capsules or a placebo for several weeks to see if it improves focus and reduces hyperactivity.
Fayetteville, ArkansasAges 18–55 - NCT06118580RecruitingPhase 2
Alcohol and aggression brain study
This study looks at how alcohol affects the brain in people with a history of aggression or alcohol use disorder. You may be able to join if you're a right-handed adult who drinks regularly and fits one of the specific groups being studied.
Columbus, OhioAges 21–55 - NCT06144736RecruitingPhase 2
Surgery for stage 2 seminoma testicular cancer trial
This trial is testing whether removing affected lymph nodes with surgery (RPLND) works well alone for seminoma testicular cancer that has spread to nearby nodes but is still relatively small. It is for patients who have not had extensive chemo or radiation.
DüsseldorfAges 18–99 - NCT06160232RecruitingPhase 2
Psilocybin therapy for severe alcohol use disorder
This trial tests whether psilocybin, a psychedelic substance, combined with talk therapy can help people with severe alcohol use disorder stop or reduce drinking. Participants will first complete a 4-week inpatient detox program before receiving psilocybin in a supervised setting.
BrusselsAges 21–64 - NCT06162247Recruiting
Registry study for heart patients in intensive care
This study tracks patients with sudden heart problems admitted to a special heart intensive care unit. It helps doctors learn more about these conditions to improve future care.
NaplesAges 18 years+ - NCT06187090Recruiting
Supplement therapy for adults with autism
This trial tests whether a specific supplement can help adults with Level 1 autism. It is open only to Italian-speaking participants aged 18–35 who do not have other major mental health or brain conditions.
Udine, UDAges 18–35 - NCT06218030RecruitingPhase 4
L-methylfolate for treatment-resistant anxiety
This study tests whether adding L-methylfolate (a form of vitamin B9) to your current antidepressant can help with generalized anxiety disorder that has not responded to other treatments. It is for adults who are already on a stable dose of an SSRI or SNRI medication.
Kingston, OntarioAges 18–65 - NCT06262412Recruiting
Online CBT for teens with body dysmorphic disorder
This trial tests an internet-based cognitive-behavioral therapy program for children and teenagers (ages 12-17) with body dysmorphic disorder. It aims to help them manage distressing thoughts about their appearance with support from a parent or caregiver.
GothenburgAges 12–17 - NCT06268665RecruitingPhase 2
Tart Cherry Juice for Preventing Nerve Damage from Chemotherapy
This study tests whether tart cherry juice can help prevent nerve damage (peripheral neuropathy) caused by the chemotherapy drug paclitaxel. Participants drink tart cherry juice daily during their 12 weeks of paclitaxel treatment.
Sacramento, CaliforniaAges 18 years+ - NCT06272149RecruitingEarly Phase 1
Gene Therapy for Infants With Type 2 Gaucher Disease
This trial tests a new gene therapy (VGN-R08b) for infants with Type 2 Gaucher disease, a rare genetic condition that affects the brain and body. The goal is to see if the treatment is safe and can help improve symptoms.
Shanghai, Shanghai MunicipalityAges birth–2 years - NCT06273527RecruitingPhase 2/Phase 3
Thinking skills training for mood and anxiety
This study tests whether a computerized training program can help people with mood, anxiety, or trauma-related disorders who struggle with repetitive negative thinking. If you are an outpatient and can have an MRI, this may be a good fit.
San Diego, CaliforniaAges 21–55 - NCT06274112Recruiting
Using brain stimulation to understand social motivation in depression or social anxiety
This study uses transcranial magnetic stimulation (TMS), a non-invasive brain stimulation technique, to explore how the brain processes social motivation in people with major depressive disorder or social anxiety disorder. Understanding these brain processes could help develop new treatments for social avoidance.
Auburn, AlabamaAges 25–50
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Common questions
- Are there clinical trials for bipolar disorder i or ii?
- Yes. Clin2 currently lists 2,381 recruiting bipolar disorder i or ii studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bipolar disorder i or ii trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bipolar disorder i or ii trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.