Clinical trials
Bipolar Disorder I or II clinical trials
Below are recruiting bipolar disorder i or ii clinical trials, each written for real people, not researchers. We’re tracking 2,361 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05889520Recruiting
Study of ultraprocessed foods in breast milk
This study looks at whether eating more ultraprocessed foods changes what shows up in breast milk. It may help understand how diet could affect breast milk for full-term babies.
NaplesAges 18–35 - NCT05892744RecruitingPhase 4
Testing brain scans to help choose depression treatment
This trial studies how brain signals measured by MRI and EEG may help doctors choose the best treatment for depression. It focuses on people with early-onset, long-lasting or recurring major depression, and tests whether these “brain biomarkers” track with treatment choice and response.
Austin, TexasAges 18–65 - NCT05894083RecruitingPhase 2
PET-Scan Tailored De-escalation for p16+ throat cancer
This trial tests a treatment plan that may lower (de-escalate) therapy intensity for certain p16+ or HPV-positive throat cancers. It uses PET scan results and tumor features to try to keep cancer control while reducing side effects.
Ann Arbor, MichiganAges 18 years+ - NCT05895513RecruitingPhase 2
Pimavanserin trial for aggression and social thinking
This Phase 2 trial tests pimavanserin, a medication that may affect brain signals, to see if it can reduce aggression and improve social thinking in people with intermittent explosive disorder (IED) or a history of aggressive behavior. If you qualify, you’ll be screened with medical tests and questionnaires and must meet medication and safety rules to participate.
Columbus, OhioAges 21–55 - NCT05909267Recruiting
Testing dopamine-targeted treatment for depression and body inflammation
This study looks at how changing dopamine signaling may affect motivation and movement in people with major depression, and it also involves healthy volunteers. It may help researchers understand whether dopamine changes can improve symptoms and how inflammation may relate to brain function.
SteglitzAges 18–65 - NCT05919108RecruitingPhase 2
Neratinib before surgery for HER2-mutated invasive lobular breast cancer
This Phase 2 trial tests neratinib given before surgery to treat stage I–III invasive lobular breast cancer that has a specific HER2 mutation and is hormone-receptor positive. It may help shrink the tumor and improve control of cancer before and after surgery.
Atlanta, GeorgiaAges 18 years+ - NCT05922878RecruitingPhase 2
ALTO-300 study for moderate to severe depression
This trial tests ALTO-300 as an add-on treatment for people with moderate to severe major depressive disorder (MDD). It aims to see whether ALTO-300 helps improve depression symptoms when you’re already on a stable antidepressant.
Phoenix, ArizonaAges 18–70 - NCT05923944Recruiting
Video game play to help teens with anxiety
This trial studies whether guided video game play can reduce anxiety symptoms in adolescents. It may help by using structured gameplay sessions as a form of mental support.
HaifaAges 11–15 - NCT05929911Recruiting
Talk therapy for PTSD in people living with HIV
This trial tests whether trauma-focused psychodynamic talk therapy can reduce symptoms of post-traumatic stress disorder (PTSD) in people who also live with HIV. It may help by offering structured therapy alongside stable medication.
The Bronx, New YorkAges 18–65 - NCT05936242Recruiting
Study of after-meal blood sugar response in type 1 diabetes
This study looks at what affects your blood sugar after you eat, in people with type 1 diabetes. The results may help improve how after-meal blood sugar is understood or managed.
NaplesAges 18–70 - NCT05939570Recruiting
Study about surgery day cancellations and neighborhood support
This study asks parents or guardians of children who had a surgery day canceled. It looks at how neighborhood circumstances may affect care, and it only includes families who speak specific languages.
Columbus, OhioAges Up to 18 years - NCT05942651Recruiting
tMS for impulsivity in borderline personality disorder
This trial studies whether magnetic brain stimulation (tMS) can reduce impulsive symptoms in people with borderline personality disorder. It may help by changing how brain networks involved in impulse control work.
Bron, AURAAges 18 years+ - NCT05943119RecruitingPhase 2
Radiation planning after sinus surgery using dose painting
This trial tests a specialized way of planning radiation (“dose painting”) for people with cancer of the sinuses after they’ve had endoscopic surgery. It may help deliver the right radiation dose to different tumor areas while sparing nearby normal tissues.
CaenAges 18 years+ - NCT05950698Recruiting
Study of obesity and bariatric surgery with mental and social factors
This study looks at how personal mental health and life circumstances relate to outcomes after bariatric (weight-loss) surgery. It may help the team understand what supports improve recovery and health after surgery.
Rio de Janeiro, Rio de Janeiro, BrazilAges 18–60 - NCT05954078RecruitingPhase 3
ctDNA-guided chemotherapy after colon cancer surgery
This trial checks whether a special blood test (ctDNA methylation) can help decide the best chemotherapy after surgery for people at higher risk of colon cancer coming back. It may help spare some patients unnecessary treatment while aiming to improve outcomes for those likely to relapse.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT05957055RecruitingPhase 2
ADHD medicine compared for kids with type 1 diabetes
This Phase 2 study compares two ADHD medicines—lisdexamfetamine and methylphenidate—in children who have ADHD and type 1 diabetes. It’s designed to see which option works better and is safe/effective for managing ADHD without causing major problems for diabetes care.
Lodz, Łódź VoivodeshipAges 8 years–16.5 years - NCT05977998RecruitingPhase 2
Paclitaxel given during surgery for stomach cancer spread to the belly
This trial studies whether adding paclitaxel chemotherapy around the time of surgery can improve outcomes for people with stomach or gastroesophageal junction adenocarcinoma that has spread to the lining of the abdomen (peritoneum). It targets cancers confirmed by testing of belly fluid or by laparoscopy/laparotomy, and may help by treating cancer cells right at the time of surgery.
Houston, TexasAges 18 years+ - NCT05985850RecruitingPhase 2
Can cannabis help with opioid addiction treatment?
This trial tests if adding a specific cannabis product to standard methadone treatment helps people with opioid use disorder. It's for adults over 25 who recently started methadone and have used cannabis before.
Vancouver, British ColumbiaAges 25 years+ - NCT05987761Recruiting
Social skills training for teens with autism
This study tests a social skills training program for teens with autism who are higher functioning. It uses brain scans to see how the training might work, and your teen must be willing to come in for weekly sessions for 9 weeks.
Palo Alto, CaliforniaAges 11–14 - NCT05988645Recruiting
Study of a new device to improve colonoscopy
This trial tests a new tool called MiWEndo that helps doctors better see and remove polyps during a colonoscopy. It is for people who already have a polyp in the rectum that needs to be taken out.
BarcelonaAges 18 years+ - NCT05996900Recruiting
Brain stimulation study for adults with epilepsy
This study uses advanced brain monitoring and noninvasive magnetic stimulation to understand how repetitive brain stimulation works in people with epilepsy who are already scheduled for hospital monitoring. It may help develop better treatments for seizures.
Stanford, CaliforniaAges 18–65 - NCT06001086RecruitingPhase 2
Disitamab Vedotin plus Pyrotinib for HER2-positive early breast cancer
This trial tests a combination of two targeted drugs (Disitamab Vedotin and Pyrotinib) for people with HER2-positive early breast cancer. It aims to see if this treatment can improve outcomes before standard therapy.
Nanjing, JiangsuAges 18 years+ - NCT06004115RecruitingPhase 4
Brain scanning study for depression and anxiety
This study uses brain scans (fMRI) to understand how people with both depression and anxiety respond to threat. If you have either or both conditions, participating could help researchers find better treatments.
Tulsa, OklahomaAges 18–65 - NCT06005194Recruiting
Exercise therapy via telehealth for depression after brain injury
This study tests whether an exercise program delivered through video calls can help treat major depression in people who have had a traumatic brain injury. If you are at least one year past your injury and have symptoms of depression, you may be able to join.
Seattle, WashingtonAges 18–64
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Common questions
- Are there clinical trials for bipolar disorder i or ii?
- Yes. Clin2 currently lists 2,361 recruiting bipolar disorder i or ii studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bipolar disorder i or ii trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bipolar disorder i or ii trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.