Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,063 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07388576Recruiting
AP-Brain supplement for attention in healthy young adults
This trial tests a supplement called AP-Brain to see if it helps with attention and focus in healthy young adults (ages 18–39) who feel they have attention problems. It compares different doses to find the safest and most effective one.
London, OntarioAges 18–39 - NCT07388043Recruiting
AP-Brain for memory in older adults with memory concerns
This trial tests a supplement called AP-Brain to see if it helps with memory and thinking in healthy middle-aged and older adults who notice memory problems. You would take different doses of the supplement or a placebo for several weeks and complete memory tests.
London, OntarioAges 40–79 - NCT03911388RecruitingPhase 1
HSV G207 for Children with Recurrent Cerebellar Brain Tumors
This trial is testing a virus called HSV G207, which is injected directly into the tumor, to treat children and young adults with a type of brain tumor in the cerebellum that has come back or not responded to standard treatments.
Birmingham, AlabamaAges 3–22 - NCT07717827Recruiting
Brain tumor surgery guided by brain wiring maps
This trial uses advanced brain scans to create a detailed map of your brain's wiring before surgery. This helps surgeons remove more tumor safely while protecting important areas that control movement, language, and vision.
Palermo, PAAges 18 years+ - NCT03586258Recruiting
Brain scan and memory testing for people with brain injury
This study uses memory and thinking tests along with brain scans (likely MRI) to understand how different types of brain damage affect thinking. It may help doctors learn more about brain-related cognitive problems.
CaenAges 18 years+ - NCT03861299Recruiting
Awake brain surgery versus sleep surgery for glioblastoma
This study compares two ways of doing brain surgery for glioblastoma: doing parts of the operation while you are awake, versus doing it fully under general anesthesia (sleep). It aims to see which approach is safer and better for protecting brain functions like speech and movement while removing the tumor.
GhentAges 18–90 - NCT04510051RecruitingPhase 1
CAR T cell therapy for IL13Rα2 positive pediatric brain tumors
This Phase 1 study tests a type of immune therapy (CAR T cells) for children with brain tumors that come back or do not respond to standard treatment. The cells are given after chemotherapy that temporarily lowers the body’s immune system, which may help the CAR T cells work better.
Duarte, CaliforniaAges 4–25 - NCT04689048RecruitingPhase 1
Testing a brain scan tracer for large, staged brain metastases
This Phase 1 study tests an injected radioactive tracer (18F-fluciclovine) to improve how doctors image and assess large brain metastases. It may help guide treatment when you’re receiving staged stereotactic radiosurgery (focused radiation in steps).
Miami, FloridaAges 18 years+ - NCT05663034Recruiting
Compare CBT-I vs MBTI for sleep and trauma symptoms after TBI
This study compares two types of talk-based therapy to help veterans with long-lasting insomnia after a traumatic brain injury (TBI), and also looks at related post-trauma stress symptoms. It may help you improve sleep and reduce how much these symptoms affect daily life.
Eglin Air Force Base, FloridaAges 18 years+ - NCT05685069Recruiting
Studying stroke risk factors in people with silent brain infarcts
This study looks for what may have caused “silent” mini-strokes in the brain that were found on MRI, and which risk factors might be changeable. It may help doctors better understand how to prevent future stroke in people who have no clear stroke symptoms from the finding.
ToursAges 16 years+ - NCT05762796Recruiting
Brain scan and stimulation study for kids with mild concussion
This study tests whether a brain “stimulation” approach, paired with brain imaging (MRI), can help children who still have symptoms after a mild concussion. There is also a comparison group of children without concussion history.
Buffalo, New YorkAges 10–15 - NCT05768490RecruitingPhase 3
Radiation plus targeted pills for EGFR lung cancer brain spots
This Phase 3 study tests whether giving brain radiation early or later, along with almonertinib (a targeted pill), works better for people with EGFR-mutated non-small cell lung cancer that has a small number of brain metastases. It aims to control brain disease while checking safety and effectiveness in a carefully selected group.
Guangdong, GuangzhouAges 18–75 - NCT05921786Recruiting
Study brain surgery samples to map brain connections and signals
This study uses a special microscope to study how brain tissues communicate and signal. It will look at brain tissue taken during surgery (from certain tumor or brain disease cases) to better understand brain wiring and improve reading of lab signals.
TaipeiAges 18 years+ - NCT06048094RecruitingPhase 1
PET scan study for brain metastases treated with radiosurgery
This trial tests a special PET scan (18F-fluciclovine) to see how well it shows brain metastases after stereotactic radiosurgery (a precise form of radiation). It may help doctors better understand treatment effects.
Miami, FloridaAges 18 years+ - NCT06101069Recruiting
New MRI scan to tell tumor from radiation damage
This study tests a special MRI technique to better distinguish between tumor regrowth and radiation-related changes in people with brain tumors. If you've had radiation for a brain tumor and now have suspicious changes, this scan might help guide your next steps.
Cleveland, OhioAges 18–60 - NCT06118723Recruiting
Supramaximal vs maximal surgery for brain tumors
This trial compares removing as much tumor as safely possible (supramaximal resection) with standard maximal resection in people with high-grade glioma (an aggressive brain tumor). The goal is to see if more extensive removal improves survival and quality of life.
San Francisco, CaliforniaAges 18–90 - NCT06150196Recruiting
Brain health classes for veterans with TBI
This trial tests whether brain health and wellness classes can help veterans who have had multiple mild traumatic brain injuries and also have PTSD. The classes aim to improve cognitive symptoms like memory and attention.
Martinez, CaliforniaAges 18–75 - NCT06328686RecruitingEarly Phase 1
Arginine and whole brain radiation for brain metastases
This trial tests whether taking arginine (an amino acid) during whole brain radiation therapy can help people with brain metastases from any type of cancer. It looks at how the treatment affects the body and may improve outcomes.
Atlanta, GeorgiaAges 18 years+ - NCT06370520Recruiting
Teen emotions screening after mild brain injury
This study screens teens aged 11 to 17 for emotional and mental health problems after a mild traumatic brain injury (mTBI, also called concussion or minor head injury). The goal is to find out if the hospital screening helps identify teens who may need extra support.
Sacramento, CaliforniaAges 11–17 - NCT06471465RecruitingPhase 3
Avastin for brain swelling after radiation
This trial tests a drug called Avastin (bevacizumab) for people with brain swelling (radionecrosis) after radiation. It's for those whose symptoms don't get better with steroids or come back when steroids are reduced.
BrestAges 18 years+ - NCT06556043Recruiting
Brain stimulation to improve ankle control in adults with and without stroke
This study uses mild brain stimulation (tDCS) to see if it can help middle-aged and older adults—both healthy and those who have had a stroke—learn ankle movements better. It tests whether stimulating different brain regions can improve motor skills and brain connections.
TaipeiAges 40–80 - NCT06560372Recruiting
Bleeding after head injury and brain blood vessel narrowing
This study looks at whether moderate to severe traumatic brain injury with bleeding around the brain can lead to a complication called cerebral vasospasm (narrowing of brain blood vessels). It's being done at Martinique University Hospital to understand how often this happens and how it affects recovery.
Fort-de-FranceAges 18 years+ - NCT06584591Recruiting
Balance training study for people with traumatic brain injury
This study tests a new balance training program called NEUROBALANCE to help improve postural control in people who have had a traumatic brain injury. It uses a non-invasive brain stimulation technique (TMS) to see if it can help improve balance and walking.
West Orange, New JerseyAges 18–75 - NCT06640582RecruitingPhase 1/Phase 2
TIL therapy with pembrolizumab for advanced brain cancer
This trial tests a new treatment for advanced brain cancers like glioma and meningioma. It combines your own immune cells (tumor-infiltrating lymphocytes or TILs) with an immunotherapy drug (pembrolizumab) to help your body fight the tumor. It's for people who have tried other treatments without success or have no standard options left.
Beijing, Beijing MunicipalityAges 16–90
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,063 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.