Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06523127Recruiting
Life support decisions and quality of life after severe brain injury
This study looks at patients with severe brain injuries who were in the ICU in 2022. It explores how decisions about life-sustaining treatment affect their quality of life two years later.
Saint-EtienneAges 18 years+ - NCT06533176Recruiting
Personalized brain stimulation after stroke
This study tests a new way to apply brain stimulation called TMS while watching your brain activity in real time, tailored to your personal brain state. It is for people who still have arm or hand weakness at least 6 months after a stroke.
Iowa City, IowaAges 18 years+ - NCT06542224Recruiting
Finding Brain Signals to Guide OCD Deep Brain Stimulation
This study is testing whether brain signals measured during deep brain stimulation (DBS) can help doctors better treat Obsessive-Compulsive Disorder. It may offer a new way to personalize treatment for people with severe, treatment-resistant OCD.
Chengdu, SichuanAges 18–65 - NCT06542094Recruiting
Brain stimulation for severe depression that hasn't improved with other treatments
This trial tests if deep brain stimulation (a device that sends tiny electrical pulses to mood-related brain areas) can help people with tough-to-treat depression. It uses brain-signal monitoring to see which patterns predict improvement.
Chengdu, SichuanAges 18–65 - NCT06543563Recruiting
Esketamine for anesthesia during Parkinson's brain surgery
This trial is testing whether a drug called esketamine (related to ketamine) can help make the anesthesia experience better for people with Parkinson's disease who are undergoing a specific brain surgery called bilateral STN-DBS. If you qualify, you would receive esketamine during your procedure to see if it improves outcomes.
Beijing, Beijing MunicipalityAges 50–80 - NCT06544408Recruiting
Brain stimulation for fast relief of PTSD
This study tests a rapid, non-invasive brain stimulation treatment to reduce PTSD symptoms. It aims to offer a faster way to help adults with PTSD feel better.
Tallahassee, FloridaAges 18–65 - NCT06551987Recruiting
Insomnia treatment for military members with mild brain injury
This study tests a behavioral insomnia therapy for active-duty service members who have had a mild traumatic brain injury and continue to have sleep problems and other symptoms. It aims to help improve sleep and recovery.
Fort Cavazos, TexasAges 18–45 - NCT06561100Recruiting
Optimizing treatment for brain-injured warfighters
This trial tests ways to improve treatment for active-duty service members who have had a mild traumatic brain injury (mTBI) and still have symptoms. It aims to find the best approach to help them recover.
Camp Pendleton, CaliforniaAges 18–55 - NCT06568536Recruiting
EEG Study to Predict Recovery After Brain Injury
This study uses a special EEG test to measure brain activity in people who are not fully conscious after a recent brain injury. The goal is to find better ways to know if someone will wake up and recover thinking abilities.
Boston, MassachusettsAges 18 years+ - NCT06570135Recruiting
Brain activity during sex in men with lifelong premature ejaculation
This study looks at brain activity during sex in men with primary premature ejaculation (a lifelong condition of coming too quickly). It uses a brain imaging technique to see if there are differences in how the brain works during sexual activity.
Xi'an, ShaanxiAges 18–45 - NCT06571032Recruiting
EEG guidance for brain stimulation after severe injury
This study tests whether using brain wave monitoring (EEG) can help guide electrical stimulation treatment for people with severe traumatic brain injury. It aims to see if this approach can improve recovery.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06581003RecruitingPhase 3
Hyperbaric oxygen for veterans with lasting brain injury symptoms
This trial tests whether breathing pure oxygen inside a pressurized chamber (hyperbaric oxygen therapy) can help reduce long-term symptoms after a mild or moderate traumatic brain injury. It is for veterans and service members who have had a TBI at least one year ago and are still struggling with symptoms.
Tampa, FloridaAges 18–75 - NCT06582316Recruiting
Digital program for brain health in midlife
This study tests a digital program to help improve brain health in people aged 40–55 who have high blood pressure, high cholesterol, or type 2 diabetes. It uses an app and online sessions to offer tips and support for keeping your thinking skills sharp.
SingaporeAges 40–64 - NCT06582940RecruitingPhase 2
MRI-guided radiation for lung cancer with brain metastases
This trial tests a new way to deliver radiation to brain metastases from non-small cell lung cancer, using MRI scans to guide the treatment and reduce the area exposed. The goal is to see if this approach is safe and effective while possibly lowering side effects.
Guangzhou, GuangdongAges 18–75 - NCT06585618Recruiting
Pediatric Deep Brain Stimulation Registry
This study creates a list of children who already have or plan to get Deep Brain Stimulation (DBS) to see how it helps with movement problems. Joining helps doctors learn more about how DBS works in kids.
Boston, MassachusettsAges birth–18 years - NCT07174661Recruiting
Planning ahead for teens and young adults with advanced cancer
This study tests an educational tool to help young adults with advanced solid tumors or high-grade brain tumors think about and discuss their future healthcare wishes early. It may help you feel more prepared and in control of your care.
Scottsdale, ArizonaAges 18–39 - NCT06604000Recruiting
Goal management training for cognitive control after brain injury
This trial tests a training program called Goal Management Training (GMT) to help people who have had a brain injury improve their ability to plan, focus, and stay organized. If you have trouble with these skills and your injury happened at least a year ago, this training might help you get better at everyday tasks.
TrondheimAges 18–65 - NCT06604689Recruiting
AI-guided brain radiation for EGFR-mutant lung cancer with brain mets
This study uses AI to help doctors decide the best way to use brain radiation for people with EGFR-mutant lung cancer that has spread to the brain. It aims to improve treatment planning and outcomes for those already taking a third-generation targeted therapy.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06607523Recruiting
Prebiotic treatment for brain injury recovery
This study tests whether a prebiotic (a type of fiber that feeds healthy gut bacteria) can improve recovery from a brain injury by helping the connection between the gut and the brain. Participants include people with a recent brain injury and their family members or staff, all of whom are part of the Moody Neurorehabilitation Institute community.
Galveston, TexasAges 18 years+ - NCT06624488Recruiting
Brain injury markers after cardiac arrest and outlook
This study looks at certain proteins in the fluid around the brain and in the blood after a cardiac arrest. These proteins may help doctors predict how the patient will recover, which could guide their care.
BeijingAges 18–80 - NCT06628752Recruiting
Deep brain stimulation for severe OCD
This study tests a treatment called deep brain stimulation (DBS) for people with severe OCD that hasn't improved with standard therapies. DBS uses a device to send small electrical pulses to specific parts of the brain to help control symptoms.
Umeå, Västerbotten CountyAges 18–65 - NCT06633809Recruiting
Treating minor stroke with large artery blockage
This study tests whether a specific treatment (likely endovascular therapy) helps people who have a minor stroke caused by a blockage in a large brain artery. If you are eligible, you may receive this treatment within 24 hours of your stroke to try to improve your recovery.
Hangzhou, ZhejiangAges 18 years+ - NCT06642896Recruiting
Pupil check after medicine for brain swelling in children
This study checks how children’s pupils react after they receive a medicine to lower brain pressure. It aims to see if a quick pupil test can help doctors know if the medicine is working.
Grenoble, ISEREAges 1 month–17 years - NCT06667726RecruitingPhase 2
New PET scan for better brain tumor care
This trial studies a special PET scan called 18F-DOPA PET/CT to see if it can help doctors better manage brain tumors. It may be used before surgery, for radiation planning, or when MRI results are unclear.
Rochester, MinnesotaAges 18 years+
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.