Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,015 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06905587RecruitingPhase 3
Methylphenidate for fatigue in young brain tumor survivors
This trial tests whether the medicine methylphenidate (often used for ADHD) can help reduce severe fatigue in children and teens who have finished treatment for a brain tumor. If you're a young brain tumor survivor struggling with ongoing tiredness, this study may offer a new option.
AalborgAges 6–27 - NCT06909045Recruiting
Adaptive vs. regular deep brain stimulation for Parkinson's
This study compares two ways of using deep brain stimulation (DBS) — an adjustable ‘adaptive’ version that changes with your brain signals, versus the standard continuous setting. It aims to see which works better for people with Parkinson's disease who already have a specific type of DBS device.
LeuvenAges 18 years+ - NCT06891781Recruiting
Adaptive deep brain stimulation for Parkinson's
This study tests a new type of deep brain stimulation (DBS) that adapts to your brain activity in real time. It is for people with Parkinson's disease whose symptoms are not well managed by medication and who are already candidates for DBS surgery.
MonzaAges 18 years+ - NCT06897670Recruiting
Brain blood flow patterns in mood and memory disorders
This study uses a headband with light sensors (fNIRS) to measure blood flow in the brain while you do thinking tasks. It aims to understand differences in brain activity for people with depression, bipolar disorder, or mild memory loss.
Rochester, MinnesotaAges 18 years+ - NCT06888817RecruitingPhase 3
Bevacizumab vs steroids for brain radiation injury
This trial tests if bevacizumab works better than steroids for people with brain swelling caused by radiation. If you have this condition and meet certain health requirements, you may join.
AmsterdamAges 18 years+ - NCT06887088RecruitingPhase 2
Study of encorafenib, binimetinib, cemiplimab, and fianlimab for melanoma with brain metastases
This trial tests a combination of targeted drugs (encorafenib and binimetinib) followed by immunotherapy (cemiplimab and fianlimab) for people with advanced melanoma that has spread to the brain and is causing symptoms. The goal is to see if this approach can shrink tumors and help control the disease.
A Coruña, A CoruñaAges 18 years+ - NCT06888219Enrolling by invitation
Acupuncture for Swallowing and Tube Removal After Brain Injury
This study tests if acupuncture on the ear and body can help people with severe brain injuries regain the ability to swallow safely and have their breathing tube removed. It's for patients who are at least 1 month but no more than 3 months after a stroke or brain bleed.
FlorenceAges 18 years+ - NCT06871124Recruiting
Early brain stimulation for traumatic brain injury
This study tests whether early brain stimulation can help recovery after a moderate to severe traumatic brain injury (TBI). It might help improve thinking and awareness in patients who can already speak and follow directions.
Cincinnati, OhioAges 18–80 - NCT06878469Recruiting
Simplifying care for rare brain tumors with AI
This study uses artificial intelligence to improve care for adults with rare brain tumors who are scheduled for surgery. It aims to make treatment pathways simpler and better tailored to each patient.
Milan, PAAges 18 years+ - NCT06865222Recruiting
Magnetic brain stimulation for lingering COVID symptoms
This study tests whether a special type of magnetic stimulation (called TMS) can help with lingering symptoms after COVID-19, such as loss of smell, ringing in the ears, or fatigue. The treatment is safe and non-invasive, using a magnet placed near your head.
Rochester, MinnesotaAges 18–65 - NCT06859996Recruiting
Cognitive rehab study for memory and focus after mild brain injury
This study tests two different types of cognitive rehabilitation (education and problem-solving strategies) delivered via video appointments. It may help people with ongoing thinking and memory problems after a mild brain injury.
Seattle, WashingtonAges 18 years+ - NCT06861790Recruiting
How weight loss surgery affects brain function
This study looks at how weight-loss surgery affects brain function. You will have an MRI scan and give a small blood sample before and after surgery.
Gainesville, FloridaAges 20–75 - NCT06867809Recruiting
Spinal and brain stimulation for arm movement after neck injury
This study tests whether using a combination of spinal and brain stimulation can help improve arm and hand movement in people who have had a cervical spinal cord injury (neck area) at least one year ago. It is for those with some remaining movement but not full strength.
New York, New YorkAges 18 years+ - NCT06866691RecruitingPhase 4
Seizure prevention after traumatic brain injury
This trial tests two medicines, levetiracetam and lacosamide, to see which works better at preventing seizures in people who have had a traumatic brain injury. The goal is to find the safest and most effective way to protect your brain after injury.
Winston-Salem, North CarolinaAges 18 years+ - NCT04938362Recruiting
Study brain recovery after abscess using memory and brain scans
This study looks at how thinking and energy levels change after a brain abscess. It may help researchers understand what affects recovery and fatigue, using thinking tests and brain imaging/brain-wave checks.
OsloAges 16 years+ - NCT06839079Recruiting
Brain training for trauma survivors with head injury
This study tests a cognitive rehabilitation program for people with traumatic brain injury who have also experienced war, violence, or other trauma. It aims to improve memory and thinking skills using exercises and strategies.
Boston, MassachusettsAges 18–65 - NCT06839547Recruiting
Testing a new drug with radiation for advanced breast cancer brain tumors
This study looks at how well a new anti-tumor drug works when given along with radiation therapy for people whose advanced breast cancer has spread to the brain. It may help the radiation work better and control the cancer longer.
BeijingAges 18 years+ - NCT06839560RecruitingPhase 2
Immunotherapy plus chemotherapy and radiation for advanced breast cancer with brain metastases
This trial tests a combination of a PD-L1 inhibitor with a low-dose chemotherapy regimen and either immediate or delayed radiation therapy for people with HER2-negative breast cancer that has spread to the brain. The goal is to see if this approach helps shrink brain tumors and improve outcomes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06837363Recruiting
Smart board rehab for arm weakness after brain injury
This trial tests a smart board therapy that you can do without in-person contact to help improve arm movement if you have weakness on one side from a stroke, brain injury, or tumor. It is for people who are at least 3 months past their diagnosis and can understand simple instructions.
SeoulAges 19–85 - NCT06837324Recruiting
Smart glove therapy for arm weakness after brain injury
This study tests a smart glove system that provides arm and hand exercises at home for people who had a brain injury (like a stroke) more than 3 months ago and have weakness on one side. The goal is to improve use of the affected arm without needing frequent hospital visits.
SeoulAges 19–85 - NCT06831461Recruiting
Proton vs photon radiation for brain tumors
This study compares two types of radiation therapy for adults with primary brain tumors that have a good outlook (expected survival longer than 5 years). You will receive either standard photon radiation or the more targeted proton radiation, to see if one works better or causes fewer side effects.
MumbaiAges 18–70 - NCT06333990RecruitingPhase 3
Quetiapine for concussion symptoms in veterans
This study tests whether quetiapine (a medication that can help with mood, sleep, and thinking) reduces ongoing concussion symptoms in veterans who had a mild traumatic brain injury (mTBI) at least 6 months ago. You may join if you are already taking at least three medications for your brain or mental health symptoms and have some PTSD symptoms.
Albuquerque, New MexicoAges 18–65 - NCT06819592RecruitingPhase 3
Preventing early lung infections after severe brain injury
This study tests whether giving an antibiotic (ceftriaxone) early after a severe brain injury can prevent lung infections caused by the breathing machine (ventilator). It is for adults in the ICU who recently started on a ventilator due to a brain emergency.
Canberra, Australian Capital TerritoryAges 18 years+ - NCT06817837Enrolling by invitation
Can hypnosis help adults with brain injury?
This study tests if hypnosis can help adults with stroke or traumatic brain injury who have symptoms like anxiety, trouble sleeping, pain, or behavior issues. Researchers want to see if it's a feasible and useful addition to usual care.
Tinlot, LiègeAges 18 years+
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,015 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.