Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,015 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04847284Recruiting
Radiation during brain tumor surgery for brain metastases
This trial tests giving targeted radiation while surgeons are operating to treat brain metastases. It may help control the cancer locally at the time of surgery, especially for certain single lesions.
BarcelonaAges 18 years+ - NCT06981897Enrolling by invitation
Early cognitive rehab for moderate brain injury recovery
This trial tests whether starting cognitive rehabilitation early after a moderate traumatic brain injury helps improve thinking, memory, and daily function. If you're an adult with a moderate brain injury who is medically stable, this study may help you regain skills faster.
Cairo, ManialAges 18 years+ - NCT06973512Recruiting
Brain stimulation for severe addiction
This trial tests a new brain stimulation approach for people with severe addiction that hasn't gotten better with other treatments. It uses deep brain stimulation guided by brain mapping to try to reduce cravings and help you stay abstinent.
Toronto, OntarioAges 25–65 - NCT06970639RecruitingPhase 3
Study comparing new targeted drug plus chemo vs osimertinib for lung cancer with brain tumors
This trial tests a new targeted therapy called furmonertinib combined with chemotherapy against the current standard osimertinib for people with a specific type of non-small cell lung cancer (NSCLC) that has spread to the brain. It aims to find a better treatment option for patients whose cancer cells have a common EGFR mutation.
Guangdong, GuangzhouAges 18 years+ - NCT06966713Recruiting
Predicting recovery after severe brain injury
This study looks at patients with severe traumatic brain injury (TBI) who already need brain pressure or oxygen monitoring. Doctors want to see if certain tests can help predict how well someone might recover.
Chicago, IllinoisAges 18 years+ - NCT06963775Enrolling by invitation
Brain injury study using magnetic brain stimulation
This study uses a non-invasive magnetic stimulation technique to measure brain activity in people who have had a traumatic brain injury (TBI). It aims to see if this tool can help doctors better understand and track recovery after a head injury.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06081036Recruiting
Normal brain volumes from fetal MRI scans
This study looks at past fetal MRI scans to create a map of normal brain growth in babies before birth. It may help doctors better understand what healthy brain development looks like.
MarseilleAges 5 months–9 months - NCT06866379Recruiting
Brain study on alcohol use disorder: septal nuclei
This study uses brain scans (fMRI) to look at a small area deep in the brain called the septal nuclei, which may play a role in alcohol use disorder. It aims to understand how the brain's structure and activity relate to heavy drinking, which could lead to better treatments.
FrederiksbergAges 30–65 - NCT06958406Recruiting
Brain-heart connection after head injury
This study uses brain scans (MRI) to understand how a traumatic brain injury can affect the heart. It may help find better ways to treat the brain-heart connection after a head injury.
ShanghaiAges 18–80 - NCT06953674RecruitingPhase 3
Saline versus balanced fluids for traumatic brain injury
This trial compares two types of intravenous fluids (saline vs. balanced crystalloids) given to people with traumatic brain injury when they arrive in the emergency room. The goal is to find out which fluid leads to better outcomes.
Louisville, KentuckyAges 18 years+ - NCT06956404Recruiting
Light therapy for older adults with traumatic brain injury
This study tests whether a painless light therapy applied to the head can help older adults (55-85) who had a moderate or severe traumatic brain injury 1-2 years ago. It aims to see if the treatment improves thinking and memory.
New York, New YorkAges 55–85 - NCT06962215Recruiting
Simulation training for paramedics caring for brain tumor patients
This study tests whether training paramedics with realistic simulations can improve the hospital experience for patients with malignant brain tumors. If you are staying in neurosurgery before your diagnosis is confirmed, you may be able to join.
Brest, Brittany RegionAges 18 years+ - NCT06960096Recruiting
Cognitive decline after deep brain stimulation: an MRI study
This study uses MRI scans to see how deep brain stimulation (DBS) affects thinking and memory in people with Parkinson's disease. It may help researchers understand why some people experience cognitive changes after DBS surgery.
Charleston, South CarolinaAges 18 years+ - NCT05577598Recruiting
Brain scan study of deep brain stimulation in OCD
This trial uses a special PET scan to see how brain sugar use changes during deep brain stimulation for obsessive-compulsive disorder (OCD). It may help researchers understand what brain activity patterns relate to treatment response.
Vienna, State of ViennaAges 18–75 - NCT06951659Recruiting
Balance and vision study after brain tumor surgery
This study looks at how brain tumors and their surgery can affect your sense of balance and vision. You will be asked to do some simple tests to help researchers understand these changes.
Perth, Western AustraliaAges 18–80 - NCT06932809RecruitingEarly Phase 1
Brain Uptake Study of a New Imaging Tracer
This study uses a special PET scan to see how a new tracer (18F-JSS20-183A) moves through the body and brain. It may help researchers learn more about brain diseases like Parkinson's and Alzheimer's.
San Francisco, CaliforniaAges 40–85 - NCT06939465Recruiting
Cognitive therapy for throat and chest symptoms
This trial tests if a cognitive-behavioral therapy (a type of talk therapy that helps change thoughts and habits) can improve chronic throat and chest symptoms like heartburn, reflux, lump in throat, or trouble swallowing. It is for people who have these symptoms without a known structural problem in the esophagus.
Hualien CityAges 18–75 - NCT06939348Recruiting
Ultrasound therapy for patients with consciousness disorders
This trial tests whether ultrasound stimulation can help people with disorders of consciousness, like coma or a minimally conscious state. It aims to improve brain function and recovery for patients who have been injured for over a month.
Los Angeles, CaliforniaAges 18–79 - NCT06940232Recruiting
Blood test study for traumatic brain injury in kids
This study is testing whether a blood test can detect traumatic brain injury (TBI) in children. If successful, it could offer a quicker, less invasive way to diagnose concussions and other head injuries, reducing the need for CT scans or MRIs.
Omaha, NebraskaAges Up to 17 years - NCT06923722Recruiting
Can eating grapes help protect your brain during stress?
This study tests whether eating grapes every day for a few weeks can reduce the negative effects of mental stress on your brain and blood vessels. If you are a healthy young adult who experiences stress, you may be able to join.
Birmingham, West MidlandsAges 18–40 - NCT06924086Recruiting
Adaptive deep brain stimulation for children with epilepsy
This trial tests a new type of brain stimulation (adaptive deep brain stimulation) that adjusts in real time to stop seizures in children with Lennox-Gastaut syndrome. It's for children who haven't gotten enough help from medications and have frequent drop seizures.
LondonAges 5–14 - NCT06923683Enrolling by invitation
Social skills treatment for brain injury
This trial tests a treatment called T-ScEmo for people with brain injury who have trouble with social skills and emotions. The treatment involves you and a support person (like a partner or close friend) working together to improve social understanding and behavior.
Boekel, North BrabantAges 18–70 - NCT04111588Recruiting
PET/MRI scan to assess brain tumors and metastases
This trial tests how well a special PET/MRI scan can help doctors evaluate gliomas and brain metastases. It may help improve diagnosis and treatment planning by comparing scan results with tissue samples or surgery findings.
BergenAges 18 years+ - NCT06905587RecruitingPhase 3
Methylphenidate for fatigue in young brain tumor survivors
This trial tests whether the medicine methylphenidate (often used for ADHD) can help reduce severe fatigue in children and teens who have finished treatment for a brain tumor. If you're a young brain tumor survivor struggling with ongoing tiredness, this study may offer a new option.
AalborgAges 6–27
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,015 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.