Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06400901Recruiting
Brain signals during recovery from anesthesia for DBS patients
This trial records brain activity during recovery from general anesthesia in people undergoing deep brain stimulation (DBS) surgery. It aims to understand how the brain wakes up after anesthesia.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06401824RecruitingPhase 2
Combination drug therapy for lung cancer with brain spread
This trial tests a combination of two drugs, sacituzumab govitecan and bevacizumab, for people with a specific type of lung cancer (non-squamous) that has spread to the brain. It aims to see if this treatment can shrink brain tumors and improve outcomes.
AmsterdamAges 18 years+ - NCT06426615Recruiting
Understanding brain signals in unresponsive states after injury
This study looks at brain activity in people who are unresponsive after a brain injury. It uses advanced brain scans to see if there are hidden signs of consciousness, which could help doctors better understand and care for these patients.
Leuven, Vlaams-BrabantAges 18 years+ - NCT06429774Recruiting
Comparing hospital treatments for traumatic brain injury
This study compares how well different hospital teams work together to treat people with traumatic brain injury. It aims to find the best care approach to help patients recover.
Beijing, Beijing MunicipalityAges 1–89 - NCT06431685RecruitingPhase 1
Brain radiation, immunotherapy, and chemo for lung cancer spread
This trial tests a combination of low-dose radiation to the whole brain, immunotherapy, and chemotherapy given through a lumbar puncture. It is for people with lung cancer that has spread to the lining of the brain and has not responded to standard treatments.
Chengdu, SichuanAges 18–75 - NCT06442748RecruitingPhase 3
Short vs long seizure medicine in brain tumor patients
This study compares stopping seizure medicine (levetiracetam) after 6 months versus continuing it longer for people with primary brain tumors. It aims to find out if it is safe to stop the medication sooner and may help you avoid long-term side effects.
Udupi, KarnatakaAges 18 years+ - NCT06446505Recruiting
Decision aid for deep brain stimulation in Parkinson's
This study tests a decision aid to help people with Parkinson's disease who are being considered for deep brain stimulation (DBS) surgery. The goal is to see if the tool helps patients make more informed choices about their treatment.
Aurora, ColoradoAges 18 years+ - NCT06449989Recruiting
Comparing genetics of colorectal cancer and its brain spread
This study compares the genetics of the original colorectal cancer with the cancer that has spread to the brain. It aims to understand how the tumor changes when it metastasizes, which may help guide future treatments.
Moscow, MoscowAges 18 years+ - NCT06451887Recruiting
Predicting brain swelling after stroke treatment
This study looks at how to predict dangerous brain swelling after endovascular treatment for large artery stroke. It uses CT scans to identify patients at risk, which could help doctors monitor and treat them more closely.
Hangzhou, ZhejiangAges 18–80 - NCT06463808Recruiting
Heart recovery after heart attack with added protein therapy
This trial tests if adding a protein called rhBNP (which helps the heart relax) to standard care after a heart attack and stent improves heart recovery and pumping strength over time.
Nanjing, JiangsuAges 18–75 - NCT06467708Recruiting
Ear Stimulation for ICU Patients with Traumatic Brain Injury
This study tests a very small electrical device placed on the ear to see if it can help people with traumatic brain injury recover in the intensive care unit (ICU). The device sends gentle pulses to a nerve that may calm inflammation and improve brain function.
Dallas, TexasAges 18 years+ - NCT06469983Recruiting
Robotic vs. traditional standing therapy for severe brain injury
This trial compares using a robotic device versus standard therapy to help people with severe brain injury practice standing. It tests whether the robotic approach leads to better recovery of standing ability.
Sant'Angelo dei Lombardi, AvellinoAges 18–75 - NCT06476093Recruiting
Radiation plus anlotinib for lung cancer brain spread
This trial tests a combination of focused radiation (stereotactic radiosurgery) and an oral targeted therapy called anlotinib for people with non-small cell lung cancer that has spread to the brain. It may offer a way to control brain metastases without more invasive procedures.
Lianyungang, JiangsuAges 18–80 - NCT06480162Recruiting
How breathing machines affect the brain's memory center
This trial studies how mechanical ventilation (breathing machine) affects the hippocampus, a part of the brain important for memory. It may help people who already have an electrode in their hippocampus understand how breathing support impacts brain function.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06542107Recruiting
Weaning from a breathing machine after brain injury
This study looks at the best way to help people with a recent brain injury come off a breathing machine (ventilator). It aims to improve the weaning process and reduce time on the ventilator.
Nanjing, JiangsuAges 18 years+ - NCT06839079Recruiting
Brain training for trauma survivors with head injury
This study tests a cognitive rehabilitation program for people with traumatic brain injury who have also experienced war, violence, or other trauma. It aims to improve memory and thinking skills using exercises and strategies.
Boston, MassachusettsAges 18–65 - NCT04867317RecruitingPhase 3
Growth hormone treatment for veterans with mild TBI and deficiency
This Phase 3 study tests whether replacing growth hormone in veterans with mild traumatic brain injury (mTBI) and low adult growth hormone can improve quality of life. If you qualify, you’ll be screened with hormone blood tests and memory/mental health checks before starting treatment.
Birmingham, AlabamaAges 21–55 - NCT06496971RecruitingPhase 3
Testing focused ultrasound plus Avastin for recurrent glioblastoma
This study tests whether adding focused ultrasound to the standard drug Avastin (bevacizumab) can help treat recurrent glioblastoma. The ultrasound may help more of the drug reach the tumor.
TaipeiAges 18–80 - NCT06500455RecruitingPhase 3
Standard vs longer radiation for brain metastases
This trial compares the usual short course of radiation therapy (one session) to a longer course (up to 5 sessions) for people with cancer that has spread to the brain. The goal is to see if the longer course works better and causes fewer side effects.
Tucson, ArizonaAges 18 years+ - NCT06501391RecruitingPhase 2
Brain radiation plus chemo-immunotherapy for untreated NSCLC with stable brain metastases
This trial tests whether combining brain radiation with chemotherapy and immunotherapy can help people with advanced lung cancer that has spread to the brain but has not yet been treated. It is for those whose tumors do not have certain gene mutations (EGFR, ALK, ROS1).
ShanghaiAges 18 years+ - NCT06501521Recruiting
Non-invasive brain tumor testing and monitoring
This study is testing a new, non-invasive way to diagnose and monitor brain tumors. It may offer a less risky option compared to traditional biopsies.
OlomoucAges 18–99 - NCT06503484Recruiting
Brain training with light for stroke arm recovery
This trial tests whether a brain-computer interface (BCI) using near-infrared light can help stroke survivors improve hand and arm movement. You'll receive a type of brain training called neurofeedback during the study.
Hong Kong, Hong KongAges 18–75 - NCT06504238Recruiting
Non-invasive monitoring for acute brain injury
This trial tests special cameras and sensors that check your brain without surgery. It may help doctors watch for brain swelling and other problems more safely.
Boston, MassachusettsAges 18 years+ - NCT06506578Recruiting
Nausea from brain radiation for benign tumors
This trial looks at nausea caused by radiation treatment for non-cancerous brain tumors. It aims to understand how common and severe nausea is when the radiation targets a specific part of the brain.
BordeauxAges 18 years+
Hear when a new Brain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.