Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,059 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06370845RecruitingEarly Phase 1
Smell test to find natural odor in spinal fluid
This study investigates whether a natural smell can be detected in the fluid around your brain and spine (cerebrospinal fluid) after you sniff it. It aims to understand how smells enter the brain in people with different body weights who are already scheduled for a routine spinal tap.
BaselAges 18–60 - NCT06374667Recruiting
Skull bone injection vs. IV for large stroke
This trial tests a new way to give medicine for a large stroke on one side of the brain. The medicine is injected into the skull bone instead of through a vein, and researchers want to see if it works better and is safe.
Wuhu, AnhuiAges 18–80 - NCT06375265Recruiting
Sleep improvement program for older surgery patients
This trial tests a digital sleep improvement program for older adults who are about to have knee or hip replacement surgery. It aims to help you sleep better before and after surgery, which may improve your brain health and recovery.
Boston, MassachusettsAges 65 years+ - NCT06377371RecruitingPhase 4
Intraoperative tracing of meningioma with copper-64 DOTATATE
This trial tests a special imaging agent called [Cu64]DOTATATE that helps surgeons see meningioma tumors during surgery. It may make tumor removal more complete and safer.
New York, New YorkAges 18–99 - NCT06377696RecruitingPhase 2
Metformin study for brain tumor survivors after radiation
This study tests whether metformin, a common diabetes medicine, can help protect thinking and memory skills in people who have had radiation for a brain tumor. You will use a smartwatch and take online tests from home to track your progress.
Rochester, MinnesotaAges 18 years+ - NCT06381388Recruiting
Brain connection study for arm recovery after stroke
This study looks at how the two sides of your brain work together to help your arm recover after a stroke. It uses brain stimulation (TMS) and MRI scans to understand brain healing and may help guide future treatments.
Utrecht, UtrechtAges 18 years+ - NCT06381674Recruiting
Wearable tech for balance rehab after concussion
This study tests whether a wearable device can help people with balance and vision problems after a mild concussion. You will use the device to guide your own exercises and help improve your recovery.
Portland, OregonAges 18–60 - NCT06386510Recruiting
Nerve stimulation to improve arm function after stroke
This trial tests whether stimulating certain nerves in the head can help improve arm movement and brain recovery in people who had a stroke more than 6 months ago. It may be an option if you still have some arm movement but are not currently in rehab.
Laval, QuebecAges 18–85 - NCT06386588Recruiting
Sound during sleep for brain health in schizophrenia
This study tests if playing sounds during sleep can improve brain function in people with schizophrenia. You will be asked to do a finger tapping task while we measure your brain activity with MRI.
Charlestown, MassachusettsAges 18–45 - NCT06387914Recruiting
Deep brain stimulation for chronic stroke pain
This trial tests whether deep brain stimulation (using a device implanted in the brain) can help relieve severe, long-lasting pain caused by a stroke. It is for people who have tried other treatments without success.
Oxford, OxfordshireAges 21 years+ - NCT06399731Recruiting
Brain stimulation for mild thinking problems in Parkinson's
This trial tests if non-invasive brain stimulation can help with memory and thinking problems (mild cognitive impairment) in people with Parkinson's disease. It uses magnetic pulses and mild electrical current to stimulate the brain over a few weeks.
Amsterdam, North HollandAges Any age - NCT06399952Recruiting
Natural history study for Baker Gordon syndrome
This study follows people with Baker Gordon syndrome over time to better understand the condition. Participants and their caregivers share medical records and complete tests and questionnaires.
Columbia, MissouriAges birth–99 years - NCT06401993Recruiting
Brain connection study of tinnitus treatment with Chinese medicine
This study tests a traditional Chinese medicine treatment called 'Dao qi Tong Luo' for chronic tinnitus. It uses a safe brain scan (fNIRS) to see how the treatment affects brain connections related to hearing.
HangzhouAges 20–55 - NCT06406855Recruiting
Brain-controlled spinal stimulation walking therapy for spinal cord injury
This trial tests a therapy that uses a brain-controlled device to stimulate your spinal cord while you practice walking. It aims to help people with incomplete spinal cord injury improve their walking ability.
Miami, FloridaAges 18–70 - NCT06409338Recruiting
Ear nerve stimulation for Parkinson's motor symptoms
This study tests whether a gentle nerve stimulation on the ear (taVNS) can improve movement symptoms in Parkinson's disease. It aims to understand how this stimulation affects the brain.
Nanjing, JiangsuAges 40–80 - NCT06409754Recruiting
Brain-computer interface for arm recovery after stroke
This trial tests a brain-computer interface system that helps move your arm using electrical stimulation. It is for people who have had a stroke at least 6 months ago and have lasting weakness in one arm.
Mexico City, Mexico CityAges 18 years+ - NCT06418113RecruitingPhase 1
Radiation and chemo before surgery for glioblastoma
This trial tests giving radiation and chemotherapy before surgery for glioblastoma. It aims to see if this approach is safe and may help improve outcomes for patients whose tumor can be completely removed.
MadridAges 18–75 - NCT06418698Recruiting
Brain artery calcium and clot removal outcomes
This study looks at whether calcium buildup in brain arteries affects how well clot removal (mechanical thrombectomy) works for stroke patients. You may be able to join if you have a large artery blockage, a CT scan was done, and you are having the clot removal procedure.
Guangzhou, GuangdongAges 18 years+ - NCT06426303RecruitingPhase 4
Alcohol Use Disorder Treatment in Veterans: Brain and Inflammation
This study is for veterans with alcohol use disorder who have been sober for 5 days to 3 weeks. It looks at how trauma, inflammation, and brain function relate to alcohol problems and how well treatment works. You will be in a group that gets medication or a placebo.
Portland, OregonAges 18–60 - NCT06429332RecruitingPhase 4
Care bundle study for brain bleed on CT scan
This trial is testing a set of standard care steps (a 'care bundle') for people who have a sudden brain bleed (intracerebral hemorrhage) that shows up on a CT scan. It aims to see if this bundle improves recovery and outcomes.
Oklahoma City, OklahomaAges 18 years+ - NCT06429735Recruiting
Robot-implanted brain-computer interface for severe paralysis
This trial tests a brain-computer interface (a device that lets you control a computer with your thoughts) that is implanted by a robot. It is for people with severe paralysis who may benefit from a new way to communicate or control devices.
Phoenix, ArizonaAges 22–75 - NCT06432907Recruiting
Brain signal study during movement in epilepsy patients
This study records brain signals from electrodes already placed in your brain for medical reasons. It looks at how your brain controls movement, which could help develop future devices for people with paralysis.
MoscowAges 18–70 - NCT06453733Recruiting
Non-invasive brain pressure monitor for TBI
This trial tests a new, non-invasive way to monitor pressure inside the skull for people with traumatic brain injury. It compares the new device to the standard invasive method already being used in your care.
London, EnglandAges 16–99 - NCT06454591Recruiting
Using fast MRI to understand brain injury recovery
This study uses a quick MRI scan to check brain function and predict recovery after a traumatic brain injury. It may help researchers develop better ways to assess and treat TBI patients.
Calgary, AlbertaAges 18 years+
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,059 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.