Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,015 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05767658Recruiting
Online messages to support safer infant care
This study tests whether online social network posts and text messages can help pregnant people practice safer infant care after birth. It may help you feel more prepared about feeding and safe sleep.
Boston, MassachusettsAges Any age - NCT04916652Recruiting
Study brain flexibility in Chinese toddlers using special scans
This study uses MRI brain scans to look at how “neural flexibility” develops in typically developing toddlers. It compares toddlers who drink a specific formula gum or regular cow’s milk to understand how diet may relate to brain development.
Shanghai, Shanghai MunicipalityAges 2.7 years–2.8 years - NCT05728840Recruiting
Virtual reality exercises for new attention problems after brain injury
This study tests whether virtual reality (computer-generated) exercises can improve attention after a recent brain injury, most often stroke. You may be eligible if your brain injury happened within the last month and testing shows measurable attention difficulties.
LausanneAges 18 years+ - NCT02417324Recruiting
Registering new brain tumor patients to build better care
This study collects medical information (and sometimes tumor tissue) from people diagnosed with certain brain tumors after January 1, 2012. It aims to improve understanding of these tumors worldwide so future care can be better.
AachenAges Any age - NCT05719844Recruiting
Computer tests to assess concussion recovery in young rugby players
This study checks whether a set of computer-based attention and thinking tests can help manage concussion (a brain injury) in young rugby players. It compares players who had a concussion with similarly aged players who haven’t had one.
Clermont-FerrandAges 11–25 - NCT05724173Recruiting
Test of a brain-to-computer device for ALS hand paralysis
This study checks whether a brain-computer interface (a BrainGate2 system) is safe and workable for people with ALS. If you qualify, you may be asked to try the device and complete study tasks to help researchers learn how well it can support communication or control.
Stanford, CaliforniaAges 18–80 - NCT05725993Recruiting
Study of tiny blood-vessel brain injury after head trauma
This study follows people with a moderate, non-penetrating traumatic brain injury (TBI) to see how small blood-vessel damage changes over time. It uses brain scans to learn what happens after a serious accident, which may help improve future care.
Philadelphia, PennsylvaniaAges 18–65 - NCT05741411Recruiting
Text-and-phone support after concussion for teens
This study tests whether a phone-based (mHealth) handoff and follow-up can help teens after a concussion, especially those at higher risk of long-lasting symptoms. It uses smartphone check-ins and coordination between emergency and specialty care.
Philadelphia, PennsylvaniaAges 13–18 - NCT05688683Recruiting
Brain recording during awake surgery to study motor learning
This study uses special brain recordings during an awake surgical procedure to understand how the brain learns new movement and sensation skills. If you can comfortably take part in a simple task during surgery, you may help researchers learn how learning works in humans.
ParisAges 18 years+ - NCT05683145Recruiting
Better sleep for people with moderate or severe TBI
This trial studies an approach to improve insomnia (trouble falling or staying asleep) in people who had a moderate-to-severe traumatic brain injury at least one year ago. If you qualify, it may help you restore more regular, efficient sleep after TBI.
Aurora, ColoradoAges 18–60 - NCT05704647RecruitingPhase 2
Nivolumab plus relatlimab for melanoma in the brain
This Phase 2 study tests whether nivolumab plus relatlimab can shrink or control melanoma that has spread to the brain. It may help by boosting the immune system to attack the cancer, including melanoma in brain areas that can’t be treated with prior focused radiation.
Houston, TexasAges 18 years+ - NCT05681195RecruitingPhase 2
Zanubrutinib plus pemetrexed for recurrent brain lymphomas
This trial tests zanubrutinib (a targeted lymphoma medicine) together with pemetrexed (chemotherapy) for lymphoma that has come back or did not respond well in or around the brain. It may help shrink measurable lymphoma and improve control of disease after prior treatments.
Miami, FloridaAges 18 years+ - NCT05682248Enrolling by invitation
Testing a brain assessment and stimulation system for unconsciousness
This trial studies a device and plan to assess brain function and deliver an intervention in people who are in a coma, minimally conscious state, or unresponsive arousal state after brain injury, stroke, or lack of oxygen. If you qualify, it may help doctors understand and potentially improve brain function over time.
BeijingAges 14–80 - NCT05697874Recruiting
Rare brain tumor registry for children and young adults
This study is a global registry that collects information about people with rare or hard-to-classify brain tumors (including certain genetic tumor changes). It helps researchers learn more about these tumors and may guide future studies and treatments.
Los Angeles, CaliforniaAges Up to 45 years - NCT05684094Recruiting
Study links sleep, stress, and brain reward in risky drinking
This study looks at how sleep timing and stress affect brain responses related to reward and stress in young adults who drink heavily. It may help researchers understand why some people take bigger alcohol risks and how sleep and stress could be part of safer treatment.
Eugene, OregonAges 18–24 - NCT03042962Recruiting
Brain imaging study of focal dystonia and related conditions
This trial uses brain scans to understand how brain networks work in people with focal dystonia, and to compare with family members and healthy volunteers. It may help researchers better understand what goes wrong in the brain and guide future treatments.
Boston, MassachusettsAges 21–80 - NCT05662111RecruitingPhase 2
Etidronate treatment for brain calcifications in Fahr disease
This Phase 2 study tests whether etidronate (a medicine that affects bone-calcium handling) can help people with Fahr disease or a similar condition marked by calcium deposits in the brain. It will also check safety and whether certain tests can track changes over time.
Utrecht, UtrechtAges 18 years+ - NCT05661084Recruiting
Non-surgery brain stimulation for dementia thinking and movement
This study tests whether a non-invasive brain stimulation device (tES) can improve thinking and movement problems in people with dementia. You (and your caregiver, if needed) will be asked to follow the study plan and attend visits so researchers can measure results and safety.
Boston, MassachusettsAges 55 years+ - NCT05665998Recruiting
Brain-controlled spinal stimulation for arm rehab after neck injury
This study tests a brain-controlled spinal stimulation approach to improve arm (upper limb) movement after a neck spinal cord injury. It may help people who have very limited arm function after a stable, traumatic injury, using frequent training and device-related checks.
Lausanne, Canton of VaudAges 18–75 - NCT05646901Recruiting
Study how gut bacteria may affect loss of eating control
This study looks at how gut bacteria and the brain may be involved when people struggle to control eating. It may help researchers understand the body’s signals behind eating control problems.
Girona, GironaAges 30–65 - NCT05661903RecruitingPhase 2
Spinal cord stimulator study for nerve pain and brain effects
This Phase 2 study looks at how spinal cord (or nerve-root) stimulation affects pain signals in the brain and body. You may qualify if you already have a stimulator set to a comfort mode that avoids “tingling” sensations.
Boston, MassachusettsAges 18–80 - NCT05658302Recruiting
Deep brain stimulation for Parkinson’s, using targeted stimulation
This study is testing a specific approach to deep brain stimulation (DBS) for people with Parkinson’s disease who are getting DBS surgery as part of routine care. It may help doctors learn whether circuit-based, more targeted stimulation is safe and useful for Parkinson’s symptoms.
Minneapolis, MinnesotaAges 21 years+ - NCT05658965Recruiting
EEG monitoring after early heart surgery in infants
This study looks at whether early brain-wave testing (EEG) around the time of heart surgery in very young babies can predict later learning and development issues. It may help doctors identify children who need extra support sooner.
Lille, Hauts-de-FranceAges 1 day–1 year - NCT05594017RecruitingEarly Phase 1
Test medicine to change brain rhythms and study memory
This early research study tests whether a medicine can change the brain’s electrical “rhythms” while people do memory-related tasks. It may help researchers understand how brain timing affects memory in people who are already being evaluated with specialized brain electrode monitoring.
Dallas, TexasAges 18–55
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,015 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.