Clinical trials
Breast Cancer Invasive clinical trials
Below are recruiting breast cancer invasive clinical trials, each written for real people, not researchers. We’re tracking 729 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06954623Recruiting
Partial breast re-irradiation for breast cancer recurrence
This trial tests a second round of radiation to just part of the breast for women who had a previous lumpectomy and radiation, and now have a small, early-stage cancer or DCIS in the same breast. The goal is to see if a focused re-treatment is safe and effective.
HeidelbergAges 18 years+ - NCT06961955RecruitingPhase 2
Shorter versus longer whole breast radiation for early-stage breast cancer
This trial compares a 5-day course of whole breast radiation plus a boost to the standard 9-day course for people with early-stage breast cancer who have certain risk factors, such as high-grade tumors or younger age. The goal is to see if the shorter treatment is just as safe and effective.
Salt Lake City, UtahAges 18 years+ - NCT06966453RecruitingPhase 1/Phase 2
Study of disitamab vedotin for HER2-positive advanced breast cancer
This study tests a new drug called disitamab vedotin for people with advanced breast cancer that has a certain amount of HER2 protein. Depending on your HER2 and hormone receptor status, you may be eligible for one of three groups, each with different prior treatment requirements.
Daphne, AlabamaAges 18 years+ - NCT06967103RecruitingPhase 2
New drug before breast cancer surgery
This trial tests a new drug, QL1706, given alongside chemotherapy before surgery for a certain type of breast cancer. It aims to see if this combination helps shrink tumors before they are removed.
ZhengzhouAges 18 years+ - NCT06993714RecruitingPhase 2
3D-printed absorbable breast implants for reconstruction
This trial tests a new type of breast implant made from a special material that your body can safely absorb over time. It is designed for women who need breast reconstruction after breast cancer surgery, aiming to restore shape without leaving a permanent implant.
Xi'an, ShaanxiAges 18–70 - NCT06995118Recruiting
New technique for nipple-sparing mastectomy with immediate implant reconstruction
This trial tests a special tool (HUAXI Hole 1) for a type of breast cancer surgery that removes breast tissue while saving the nipple, followed by placing an implant right away. It may be an option for women with early-stage breast cancer or those who choose preventive mastectomy.
Fuzhou, FujianAges 18–70 - NCT07003009Recruiting
Immunotherapy washout study for invasive ductal breast cancer
This study looks at how long it takes for a type of immunotherapy drug to clear out of your body in women with invasive ductal breast cancer who are about to start treatment before surgery. It may help doctors decide the best timing for future treatments.
IstanbulAges 18 years+ - NCT07003074RecruitingPhase 3
New drug TQB2102 vs standard therapy for HER2+ breast cancer
This trial tests a new medicine called TQB2102 against the standard combination of chemotherapy (docetaxel) plus two targeted therapies (trastuzumab and pertuzumab) for people with HER2-positive breast cancer that has come back or spread. The goal is to see if the new treatment works better and has fewer side effects.
Hefei, AnhuiAges 18–75 - NCT07003841Recruiting
AR-guided breast cancer localization trial
This trial tests an augmented reality (AR) tool to help surgeons locate breast cancer tumors during breast-conserving surgery. You may join if you have a single, small invasive breast tumor and have not had chemotherapy before surgery.
Seoul, Gangseo-guAges 19–80 - NCT07012720Recruiting
Comparing breast cancer treatments before surgery
This trial looks at different drug combinations given before surgery to shrink breast tumors. The goal is to find which treatments work best for different types of breast cancer, such as triple-negative, HER2-positive, or hormone-receptor-positive. If you are a woman scheduled for neoadjuvant therapy (treatment before surgery) and have not had previous cancer treatment, this study may be for you.
Xi'an, ShaanxiAges 25–75 - NCT07023887Recruiting
Exercise programs after breast cancer treatment
This study is for breast cancer survivors who have completed treatment and want to join a supervised weight-lifting program. It looks at how different exercise routines help build muscle and improve fitness.
Pittsburgh, PennsylvaniaAges 20–89 - NCT07054190RecruitingPhase 2
Testing Inavolisib in early-stage breast cancer with PIK3CA mutation
This trial is testing a drug called Inavolisib (a type of targeted therapy) given before surgery for people with early-stage, hormone receptor-positive, HER2-negative breast cancer that has a specific genetic change (PIK3CA mutation). The goal is to see if adding Inavolisib to standard endocrine therapy can shrink the tumor more effectively.
Los Angeles, CaliforniaAges 18 years+ - NCT07057427RecruitingPhase 3
Nab-paclitaxel vs TCbHP for HER2-positive early breast cancer
This trial compares two different drug combinations given before surgery to shrink HER2-positive breast cancer tumors. The goal is to see which combination works better and has fewer side effects.
Zhengzhou, HenanAges 18–70 - NCT07071038RecruitingPhase 2
Switching medication to relieve side effects from aromatase inhibitors
This trial tests whether switching to a different aromatase inhibitor or using standard treatments works better for managing side effects in breast cancer survivors. It aims to help you stay on hormone therapy longer with fewer discomforts.
Lebanon, New HampshireAges 18 years+ - NCT07071272Recruiting
Comparing two breast imaging methods before surgery
This trial compares a special mammogram with dye (CEDM) to MRI for women already diagnosed with invasive breast cancer. The goal is to see if CEDM works as well as MRI for planning surgery, potentially offering a faster or easier option.
Verona, ItalyAges 30 years+ - NCT07076485RecruitingPhase 2
Shorter radiation after surgery for node-positive breast cancer
This trial tests shorter radiation schedules for people with breast cancer that has spread to lymph nodes or is high-risk. It aims to find a shorter course of radiation that is just as effective after surgery.
Loveland, ColoradoAges 18 years+ - NCT07095023Recruiting
Oral chemo and targeted therapy before breast cancer surgery
This trial tests a combination of an oral chemotherapy pill (paclitaxel) with two targeted antibodies (pertuzumab and trastuzumab) given before surgery for HER2-positive breast cancer. The goal is to shrink the tumor and make surgery more effective.
Beijing, Beijing MunicipalityAges 18–75 - NCT07111728Recruiting
Checking tumor margins during breast cancer surgery
This study tests a new imaging tool that helps surgeons see if any cancer cells are left behind during a lumpectomy. It may reduce the need for a second surgery.
Pavia, LombardyAges 18–85 - NCT07116642Recruiting
Scar placement after breast-conserving surgery for breast cancer
This study compares how different scar placements after breast-conserving surgery affect your recovery and quality of life. By joining, you help doctors learn which scar location leads to the best outcomes for patients like you.
Leeds, West YorkshireAges 18 years+ - NCT07117864Recruiting
T-DXd with brain radiation for HER2+ breast cancer
This trial tests a new combination of a targeted drug (T-DXd) with brain radiation for women with breast cancer that has spread to the brain and is HER2-positive or HER2-low. The goal is to see if this approach is safe and works better than radiation alone.
Beijing, Beijing MunicipalityAges 18–75 - NCT07122713Recruiting
Radiation therapy for inoperable breast cancer
This trial tests whether definitive radiation therapy can effectively treat breast cancer that cannot be surgically removed. It may be an option for people whose cancer is inoperable or who choose not to have surgery.
Stony Brook, New YorkAges 18 years+ - NCT07142096Recruiting
MitoQ before surgery for triple-negative breast cancer
This trial tests whether taking the supplement MitoQ before standard surgery can help treat triple-negative breast cancer. You would take MitoQ for a short time between diagnosis and surgery to see if it slows tumor growth.
BrusselsAges 18 years+ - NCT07146295Recruiting
ICG dye to find sentinel nodes in breast cancer surgery
This trial tests using a green dye called ICG (indocyanine green) during breast cancer surgery to find the first lymph nodes (sentinel nodes) that cancer may have spread to. It aims to help doctors locate these nodes more accurately, and is for people with early-stage breast cancer that has not yet spread to the lymph nodes.
AlkmaarAges 18 years+ - NCT07159451RecruitingPhase 2
Elacestrant for premenopausal women with early breast cancer
This trial tests a new hormone therapy pill, elacestrant, given alone or with another drug to suppress ovarian function before surgery. It's for premenopausal women with early-stage, hormone receptor-positive, HER2-negative breast cancer to see if it can shrink the tumor.
VillejuifAges 18 years+
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Common questions
- Are there clinical trials for breast cancer invasive?
- Yes. Clin2 currently lists 729 recruiting breast cancer invasive studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer invasive trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer invasive trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.