Clinical trials
Breast Cancer Invasive clinical trials
Below are recruiting breast cancer invasive clinical trials, each written for real people, not researchers. We’re tracking 730 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07159451RecruitingPhase 2
Elacestrant for premenopausal women with early breast cancer
This trial tests a new hormone therapy pill, elacestrant, given alone or with another drug to suppress ovarian function before surgery. It's for premenopausal women with early-stage, hormone receptor-positive, HER2-negative breast cancer to see if it can shrink the tumor.
VillejuifAges 18 years+ - NCT07164976RecruitingPhase 1/Phase 2
Ribociclib for advanced HR+ HER2- breast cancer
This trial tests a new combination of ribociclib and anastrozole as a first treatment for advanced hormone receptor-positive, HER2-negative breast cancer that has not been treated before. It may help if you have not received any prior therapy for metastatic disease.
NagoyaAges 18 years+ - NCT07179744Recruiting
Skipping radiation for low-risk node-positive breast cancer
This trial tests whether some women with low-risk breast cancer that has spread to a few lymph nodes can safely skip radiation therapy after surgery. It aims to reduce side effects while keeping the cancer from coming back.
Guangzhou, GuangdongAges 18–70 - NCT07188246RecruitingPhase 2
Radiation and immunotherapy before chemo for breast cancer
This trial tests a new approach for breast cancer that combines a short course of focused radiation (SBRT) with an injection of the immunotherapy drug pembrolizumab directly into the tumor, followed by standard chemotherapy before surgery. The goal is to see if this combination helps shrink the tumor more effectively before surgery.
London, OntarioAges 18 years+ - NCT07214610Recruiting
Improving breast cancer outcomes in North Carolina
This study looks at why some women with invasive breast cancer do better than others. It combines information from biology, medical history, and lifestyle to find ways to improve care and outcomes.
Chapel Hill, North CarolinaAges 20–74 - NCT07218432Recruiting
TheraBionic device study for hormone-positive breast cancer
This trial tests a device called TheraBionic P1, which uses low-level radiofrequency energy, for women with early-stage hormone receptor-positive, HER2-negative breast cancer. It is given before surgery to see if it can help shrink the tumor.
Clarkston, MichiganAges 22 years+ - NCT07220135RecruitingPhase 2
Comparing two drug combos before surgery for HER2+ breast cancer
This trial tests two different combinations of chemotherapy and targeted therapy given before surgery for HER2-positive breast cancer. The goal is to see which combination works better at shrinking the tumor.
Fairway, KansasAges 18 years+ - NCT07222215RecruitingPhase 2
Capacitabine with or without elacestrant for ER+ breast cancer
This trial tests if adding a new oral targeted therapy (elacestrant) to standard chemotherapy (capecitabine) works better than chemotherapy alone for people with a specific type of advanced breast cancer that is hormone-sensitive (ER-positive) and has stopped responding to hormone therapy.
Boston, MassachusettsAges 18 years+ - NCT05412225RecruitingPhase 1
Pre-surgery radiation, then mastectomy and immediate breast reconstruction
This Phase 1 study looks at giving radiation before surgery for people with locally advanced breast cancer, then performing a mastectomy and immediate reconstruction. It aims to see whether this combined approach can shrink the cancer before surgery and safely allow reconstruction afterward.
Basking Ridge, New JerseyAges 18 years+ - NCT07260188Recruiting
Breast cancer organoids from patients before chemo
This study collects tumor tissue from breast cancer patients before they start chemotherapy to grow miniature versions of their tumors (organoids) in the lab. The goal is to understand how each tumor responds to treatment, which may help personalize future therapies.
Pavia, PVAges 18 years+ - NCT07276880RecruitingPhase 2
Chemo, immunotherapy, and radiation for lymph node-positive triple-negative breast cancer
This trial tests a combination of chemotherapy, the immunotherapy drug pembrolizumab, and low or high-dose radiation before surgery for people with triple-negative breast cancer that has spread to the lymph nodes. The goal is to see if this approach can improve treatment outcomes.
Chapel Hill, North CarolinaAges 18 years+ - NCT07289282Recruiting
Study of blood markers and chemotherapy response in breast cancer
This trial is studying tiny molecules in your blood (called microRNAs) to see if they can predict how well breast cancer responds to chemotherapy given before surgery. If you are starting neoadjuvant chemotherapy, this study may help personalize your treatment.
IstanbulAges 18 years+ - NCT07318051Recruiting
Sample collection for cancer research study
This study collects blood and tumor tissue samples from patients with certain untreated cancers to help researchers develop and improve tests. You may be eligible if you have one of the listed cancer types and have not yet started treatment.
Austin, TexasAges 18 years+ - NCT07327970Recruiting
AI test to predict breast cancer treatment response
This study tests whether an AI tool can predict how well breast cancer responds to chemotherapy given before surgery. Your tumor sample from a needle biopsy will be analyzed to see if the AI's prediction matches your actual treatment outcome.
IncheonAges 18 years+ - NCT07349069RecruitingPhase 3
HRS-8080 vs. standard hormone therapy for early breast cancer
This trial tests a new oral drug (HRS-8080) against standard hormone therapy for women with intermediate- or high-risk early breast cancer who have already completed 2 to 5 years of hormone treatment. It aims to see if the new drug can reduce the risk of cancer coming back.
Nanjing, JiangsuAges 18–75 - NCT07354165Recruiting
Financial burden in early breast cancer patients
This study looks at the financial challenges people with early-stage breast cancer face during treatment. Researchers want to understand how costs affect patients so they can find ways to help.
NaplesAges Any age - NCT07371208RecruitingPhase 2
Sac-TMT plus immunotherapy before surgery for triple-negative breast cancer
This study tests a combination of two drugs—Sacituzumab Tirumotecan (Sac-TMT) and an immunotherapy called KL-A167—given before surgery to shrink triple-negative breast tumors. It aims to improve outcomes for people with early-stage, high-risk breast cancer who have not yet had any treatment.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07373782RecruitingPhase 2/Phase 3
CPAP mask during radiation for breast cancer
This trial tests whether using a CPAP mask during daily radiation treatments for breast cancer can help protect your heart. It is for women who had a lumpectomy and need radiation to the left breast or to the right breast with lymph nodes.
LeuvenAges 40–80 - NCT07376538RecruitingPhase 2
Treating advanced breast cancer based on treatment response
This trial tests a personalized approach to treating breast cancer that has spread to nearby lymph nodes. Your surgery and radiation will be tailored to how well your cancer responds to initial chemotherapy or hormone therapy.
Beijing, Beijing MunicipalityAges 18–75 - NCT07389408Recruiting
Early breast cancer treatment patterns study
This study observes how doctors treat early breast cancer and what outcomes patients have. It's for people with hormone receptor-positive, HER2-negative breast cancer that hasn't spread to many lymph nodes.
AthensAges 18 years+ - NCT01042379RecruitingPhase 2
Adaptive drug trial for newly diagnosed breast cancer
This study tests personalized, changing treatment plans (given before surgery) to find better options for your specific breast tumor. You may be asked for extra breast-tissue testing to help match you with the most suitable study drug(s).
Birmingham, AlabamaAges 18 years+ - NCT01035112Recruiting
MRI check for suspicious breast changes
This study uses a breast MRI scan to look at suspicious areas in the breast. It may help doctors better tell which breast changes need closer follow-up like a biopsy.
Stanford, CaliforniaAges 21 years+ - NCT00477100Recruiting
Breast cancer tissue and data registry for research
This trial helps create a research “tissue registry” by collecting breast cancer tissue samples and medical information. It may help doctors better understand inflammatory or invasive breast cancer and improve future studies.
Gilbert, ArizonaAges 18 years+ - NCT00437879Recruiting
Ultrasound and MRI scans to track breast cancer response early
This study uses ultrasound and/or MRI scans to see how breast cancer responds early while you start “neoadjuvant” treatment (chemotherapy, with or without radiation before surgery). It may help doctors spot response sooner and better understand which imaging changes match treatment benefit.
Toronto, OntarioAges Any age
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Common questions
- Are there clinical trials for breast cancer invasive?
- Yes. Clin2 currently lists 730 recruiting breast cancer invasive studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer invasive trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer invasive trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.