Clinical trials · Texas
Cancer clinical trials in Texas
We’re tracking 1,482 recruiting cancer studies with a site in Texas — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Texas
- NCT05056857Recruiting
Study immune-web changes in ER+ breast cancer on tamoxifen
This trial studies how the immune system forms “neutrophil extracellular traps” (immune web material) in people with ER-positive breast cancer who take tamoxifen. It aims to understand whether tamoxifen changes this immune activity over time, which may help explain how it works.
Houston, TexasAges 18 years+ - NCT05054413Recruiting
Expert guideline survey for prostate cancer care
This study uses a structured expert survey to help build clear, agreed-upon guidelines for prostate cancer care. If you’re a board-certified clinician who actively treats prostate cancer, your input can help shape how care is recommended.
Houston, TexasAges 21 years+ - NCT05053555Recruiting
High-dose radiation treatment for hard-to-remove liver tumors
This study uses a form of targeted radiation placed inside/near the liver to treat liver tumors that can’t be surgically removed. It’s meant to shrink or control tumors, especially when they sit near blood vessels or other sensitive organs.
Houston, TexasAges 19 years+ - NCT05043012Recruiting
Testing a special MRI scan for prostate cancer diagnosis
This study checks how well a new prostate MRI scan (using a flexible coil and multiple MRI types) can correctly identify prostate cancer and help with treatment planning. You may be able to help doctors improve prostate imaging before you have surgery.
Houston, TexasAges 18 years+ - NCT05027633RecruitingPhase 2
Immunotherapy plus chemo and radiation for nasal cancer
This Phase 2 study tests a treatment plan that combines immunotherapy with chemotherapy and chemoradiation for advanced squamous cell cancer in the nasal cavity or sinuses. It aims to improve cancer control in people who are newly diagnosed and have not had prior treatment for this cancer.
Houston, TexasAges 18 years+ - NCT05049538Recruiting
Liquid blood tests to predict endometrial cancer return
This trial studies whether blood “liquid biopsies” and tumor genetic testing can help predict whether endometrial cancer will come back after treatment. Results may help doctors plan follow-up and additional care based on a person’s recurrence risk.
Houston, TexasAges 18 years+ - NCT04929223RecruitingPhase 1
Targeted drug study for metastatic colon or rectal cancer
This Phase 1 study tests targeted cancer treatments in people with metastatic colorectal cancer, using genetic “biomarker” results to match you to the right treatment group. It focuses first on safety, and also looks for early signs the treatment may work in specific tumor subgroups.
Denton, TexasAges 18 years+ - NCT04928846RecruitingPhase 3
Telisotuzumab vedotin vs docetaxel for advanced non-squamous lung cancer
This trial tests an investigational drug (telisotuzumab vedotin) against the standard chemotherapy docetaxel in people with a certain type of non-squamous lung cancer that has high levels of a protein called c-Met. It may offer a new treatment option for those whose cancer has progressed after initial therapy.
Austin, TexasAges 18 years+ - NCT04986423RecruitingPhase 2
Add ZEN003694 to enzalutamide for resistant prostate cancer
This Phase 2 study tests whether adding ZEN003694 to enzalutamide works better than enzalutamide alone in men whose prostate cancer has spread and is no longer controlled by hormone lowering treatments. It focuses on people who either did not respond well to abiraterone (poor responders) or did respond (responders), then compares outcomes between treatment groups.
Austin, TexasAges 18 years+ - NCT04970056Recruiting
Pancreatic cancer risk and early-detection registry study
This study builds a database of people at higher risk for pancreatic cancer (or certain early warning findings) to help find better ways to detect the disease early. You may be asked to complete health questionnaires and possibly donate a blood/saliva/swab sample.
Houston, TexasAges 18–90 - NCT04984551RecruitingPhase 2
Training plus support to improve palliative care for advanced cancer
This trial studies whether a program called Project ECHO can improve the quality of palliative care (comfort-focused care) for people with advanced cancer and their caregivers in underserved areas. It also involves training local health care providers so they can better support patients and families over time.
Houston, TexasAges Any age - NCT04858334RecruitingPhase 2
Olaparib after pancreatic cancer surgery for BRCA or PALB2 mutations
This trial studies whether olaparib (a targeted cancer medicine) can help prevent pancreatic cancer from coming back after surgery in people with BRCA1, BRCA2, or PALB2 mutations. You would get olaparib or a placebo (inactive pill) and be closely followed to see if recurrence is reduced.
Bryan, TexasAges 18 years+ - NCT04864054RecruitingPhase 1/Phase 2
Study T-cell therapy for advanced liver cancer
This trial tests a custom immune-cell treatment made to target a marker (GPC3) found on some liver cancers. It’s for adults with advanced HCC whose cancer has worsened after standard treatment or who couldn’t tolerate it.
Dallas, TexasAges 18 years+ - NCT04913311Recruiting
Testing markers to predict lung inflammation after lung cancer treatment
This study looks for early “predictive markers” to tell who is most likely to develop lung inflammation after standard treatment for non-small cell lung cancer. It may help clinicians spot problems sooner and tailor care, using additional monitoring during treatment.
Houston, TexasAges Any age - NCT04831580Recruiting
Robotic vs open hysterectomy for early cervix cancer
This trial compares robotic surgery to open (traditional) surgery for women with early-stage cervix cancer. The goal is to see which approach is safer and works better for cancer control and recovery.
Austin, TexasAges 18 years+ - NCT04776941Recruiting
Writing exercises to reduce stress after cancer
This study tests whether guided writing exercises can help cancer survivors manage stress. It may be a low-risk way to improve well-being after cancer, especially if you recently finished treatment.
Houston, TexasAges 18 years+ - NCT04852887RecruitingPhase 3
Testing shorter breast radiation after low-risk hormone breast cancer
This Phase 3 trial studies whether “less intense” radiation can work as well as standard radiation for certain early-stage hormone receptor–positive, HER2-negative breast cancers that have a low Oncotype DX score. It may help reduce treatment burden while keeping cancer control strong.
Cypress, TexasAges 50–70 - NCT04812366RecruitingPhase 2
Genetic test-guided treatment before prostate surgery
This trial tests different drugs before prostate surgery based on a person's genetic profile. It aims to find better treatments for high-risk prostate cancer that hasn't spread yet.
Houston, TexasAges 18 years+ - NCT04715178Recruiting
Childhood cancer sample and data registry
This study collects stored samples (like blood or tissue) and health information from people affected by cancer at a young age, including some survivors. The goal is to build a library of specimens and data that researchers can use to better understand childhood and young adult cancers.
Austin, TexasAges Any age - NCT04628767RecruitingPhase 2/Phase 3
Durvalumab plus chemo before surgery for upper tract cancer
This trial tests whether adding an immunotherapy drug (durvalumab) to chemotherapy before surgery can improve outcomes for people with high-grade upper tract urothelial cancer. It compares different treatment approaches based on whether a patient can receive cisplatin chemotherapy.
Dallas, TexasAges 18 years+ - NCT04613596RecruitingPhase 2/Phase 3
Adagrasib for KRAS G12C lung cancer, alone or with pembrolizumab
This trial studies adagrasib (an anti-cancer drug) either alone or with pembrolizumab (an immunotherapy) in people with advanced lung cancer that has a KRAS G12C mutation. It aims to shrink tumors and improve outcomes, including for people without urgent brain treatment needs.
Abilene, TexasAges 18 years+ - NCT04615013RecruitingPhase 1
NBTXR3 with chemoradiation for esophageal cancer treatment
This early-phase study tests adding NBTXR3 (a special treatment given into the tumor) to standard chemotherapy and radiation for esophageal cancer. The goal is to see if it can improve cancer control and to learn about safety and dosing.
Houston, TexasAges 18 years+ - NCT04629677Recruiting
Portal vein stent for narrowed portal blood vessels
This trial looks at whether placing a small metal stent in the portal vein and nearby veins can improve problems caused by major narrowing (or clotting) of these vessels in people with gastrointestinal cancers. If you have significant vessel narrowing, the study may offer a targeted way to relieve pressure and symptoms that are not caused by the tumor directly.
Houston, TexasAges 18 years+ - NCT04491292Recruiting
COVID-19 impact survey for MD Anderson workers
This study asks MD Anderson employees about how the COVID-19 pandemic affected their mental and emotional well-being. Your answers may help the team understand workplace needs during and after major public health events.
Houston, TexasAges 18 years+
Cancer trials by city in Texas
Where these studies are running in Texas
Institutions with a site for the recruiting cancer studies listed above.
- The University of Texas MD Anderson Cancer Center · 14 studies
- University of Texas Southwestern Medical Center · 4 studies
- Parkland Memorial Hospital · 2 studies
- Texas Oncology - Northeast Texas · 2 studies
- UT Southwestern Clinical Center at Richardson/Plano · 2 studies
- UT Southwestern Medical Center · 2 studies
- UT Southwestern/Simmons Cancer Center-Fort Worth · 2 studies
- Brooke Army Medical Center
What taking part in a cancer study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Cancer trials in other states
Common questions
- Are there cancer clinical trials in Texas?
- Yes. We're currently tracking 1,482 recruiting cancer studies with a site in Texas, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a cancer study in Texas?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Texas to take part?
- Not necessarily. These studies have a site in Texas, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a cancer trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New cancer studies open in Texas regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.