Clinical trials
Cardiac Failure clinical trials
Below are recruiting cardiac failure clinical trials, each written for real people, not researchers. We’re tracking 190 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07733960Recruiting
Pacing system study for heart pacing therapy
This trial tests a new pacing system designed to improve how pacemakers work. It may help people who need a pacemaker with left bundle branch area pacing.
Madurai, Tamil NaduAges 18 years+ - NCT07664189Enrolling by invitation
Left bundle pacing plus CRT vs. LBBP alone
This trial tests a new pacing approach that combines a left bundle branch pacemaker with standard cardiac resynchronization therapy (CRT) for people with heart failure. It aims to improve the heart's pumping efficiency compared to using the left bundle branch pacemaker alone.
Medellín, AntioquiaAges 18 years+ - NCT04984473Recruiting
Breathing muscle training during heart rehab
This study tests whether breathing muscle training, added to regular heart rehab, can improve how well people with heart failure do day-to-day. It also compares results with healthy volunteers who do not have certain health problems.
Rochester, MinnesotaAges 18 years+ - NCT06745778Recruiting
Study of heart device signals in patients with left bundle pacing
This study looks at the electrical signals recorded by a special type of pacing lead placed in the heart's left bundle branch. It aims to understand how these signals change over time in people who already have an ICD or CRT-D device.
Wenzhou, ZhejiangAges 18 years+ - NCT07217392Recruiting
Study on pacing the left bundle branch area of the heart
This study tests a new way to place a pacemaker lead in the left bundle branch area of the heart. It may help people who need a pacemaker to see if this approach is safe and works well.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT07245069RecruitingPhase 2
Can dapagliflozin protect the heart during breast cancer chemo?
This trial tests if the drug dapagliflozin can prevent heart damage caused by anthracycline chemotherapy in breast cancer patients. It aims to see if taking the drug during chemo helps keep your heart healthy.
LjubljanaAges 18 years+ - NCT00181259Recruiting
MRI scan study of heart muscle chemistry
This trial uses a special MRI scan to look at how the heart muscle uses fuel. It may help researchers understand heart conditions like dilated cardiomyopathy and coronary artery disease, especially in people with reduced heart pumping.
Baltimore, MarylandAges 18 years+ - NCT04676100Enrolling by invitation
International registry for cardiac rehabilitation programs
This study collects information about cardiac rehabilitation (CR) programs in lower-resource areas. It helps improve how CR is delivered and understood, especially where healthcare resources and awareness are limited.
DohaAges 18 years+ - NCT05646849Recruiting
App-based support to keep exercising after heart rehab
This study tests whether a phone app can help people keep up physical activity after cardiac rehabilitation. If you can use a smartphone and internet, the app support may make it easier to stay active after your rehab program.
CholetAges 18 years+ - NCT06851949RecruitingPhase 2
Vsling device for ventricular repair in heart failure
This trial tests a new device called Vsling, which is placed inside the heart to help reshape the main pumping chamber (left ventricle) in people with heart failure. It may improve your heart's strength and reduce symptoms like shortness of breath.
Be’er Ya‘aqovAges 18 years+ - NCT07023536Recruiting
Heart rehab program from home for chronic heart failure
This trial tests a cardiac telerehabilitation program for people with chronic heart failure. It is designed to see if doing rehab at home using digital tools helps improve health and quality of life.
SalernoAges 18 years+ - NCT05491655Recruiting
Testing a new pacing approach in some heart failure patients
This study looks at whether a high-intensity “His bundle” heart pacing method can help people with heart failure who have a specific heart rhythm pattern on ECG. It likely aims to improve heart pumping and symptoms in people who are otherwise a good match for an ICD and meet other criteria.
Acquaviva delle Fonti, BariAges 18–90 - NCT07243769Recruiting
Comparing exercise types for heart rehab
This trial compares core, aerobic, and combined exercise in patients doing phase II cardiac rehab. It aims to find which type works best for heart recovery.
TaipeiAges 18 years+ - NCT04982419RecruitingPhase 2/Phase 3
Remote arm treatment to protect heart and kidneys in heart failure
This trial tests whether a simple “arm cuff” treatment done before a heart artery procedure can help protect the kidneys and the heart in people with congestive heart failure. If it works, it may lower the chance of kidney injury around the time of the scan/stent procedure.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05265520Recruiting
Pacing strategy study for certain heart failure patients
This trial tests a pacing approach designed to improve how the heart beats in some people with heart failure and a specific heart rhythm pattern on ECG. If you already need a device (CRT-D) based on your results, the study may help see whether this pacing correction improves outcomes.
Phoenix, ArizonaAges 18 years+ - NCT05933083Recruiting
In-person vs telehealth heart rehab comparison study
This study compares whether heart rehabilitation done in person or by telehealth (video/phone) works as well for people with certain heart conditions. It may help you and others choose the safest and most effective way to receive cardiac rehab.
San Francisco, CaliforniaAges 18 years+ - NCT06610019Recruiting
Heart imaging study using MRI
This study uses heart MRI scans to learn more about cardiovascular health in adults. If you are 18 or older and have been referred for a heart MRI at Montefiore, you may be able to join.
The Bronx, New YorkAges 18 years+ - NCT07711821Recruiting
Heart failure screening in primary care for older adults
This trial is testing a simple screening tool to find early signs of heart failure in people aged 50 or older, especially those with risk factors like diabetes or high blood pressure. If you're at risk, this could help catch heart problems sooner.
AmadoraAges 49 years+ - NCT05327062Recruiting
Noninvasive mapping to guide a heart resynchronization device
This trial tests a noninvasive way to map your heart’s wiring and veins to help guide placement of a heart resynchronization therapy (CRT) device. If you have certain abnormal heart rhythm and weak heart pumping, it may help doctors place the therapy more accurately and safely.
Chicago, IllinoisAges 18 years+ - NCT06208007Recruiting
Predicting heart failure with stiff arteries
This study looks at whether stiffer arteries can help predict a type of heart failure where the heart doesn't relax properly (HFpEF). It's for people who have risk factors like high blood pressure, diabetes, or being older, and who may have early signs of heart trouble.
Göttingen, Lower SaxonyAges 18 years+ - NCT05961748Recruiting
Brain and heart illness registry for adults in China
This study is a registry that collects health information from adults who have certain new heart and/or brain conditions. It may help researchers understand how these problems occur together and improve future care planning.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04141605Enrolling by invitation
Heart transplant candidates matched for better heart preservation
This study creates a worldwide registry and information database to help improve how donor hearts are preserved for transplant. If you are a heart transplant candidate, your details may be recorded to see what matching and preservation approaches work best.
Stanford, CaliforniaAges Any age - NCT05089149Recruiting
Check how lung ultrasound helps manage heart failure congestion
This study looks at people with long-term worsening heart failure who are coming to the hospital for a planned visit, to see how checking “congestion” (fluid buildup) may guide care. It may help the team understand whether lung ultrasound can better assess who needs treatment changes.
Vandœuvre-lès-NancyAges 18 years+ - NCT04332692Recruiting
Check if a lung ultrasound helps evaluate discharge after heart failure
This study looks at whether doing lung ultrasounds can better assess people right before they leave the hospital after an acute heart failure flare. It may help doctors decide when someone is ready for discharge and tailor care to reduce risk after leaving.
Vandœuvre-lès-NancyAges 18 years+
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Common questions
- Are there clinical trials for cardiac failure?
- Yes. Clin2 currently lists 190 recruiting cardiac failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.