Clinical trials
Cardiac Surgery clinical trials
Below are recruiting cardiac surgery clinical trials, each written for real people, not researchers. We’re tracking 310 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06637137Recruiting
Blood management for cardiac surgery patients
This trial studies a program to manage blood levels before, during, and after heart surgery. It may help reduce the need for blood transfusions and improve recovery.
RomaAges 18 years+ - NCT06817239Recruiting
Low-dose esketamine for preventing confusion after surgery in older adults
This study tests whether a low dose of the medicine esketamine can help prevent confusion after surgery in older adults at higher risk. You may qualify if you are 65 or older, planning a major non-cardiac surgery, and have certain health conditions like high blood pressure or diabetes.
Fuzhou, FujianAges 65–90 - NCT05740397Recruiting
Testing blood pressure targets during heart-lung bypass
This trial compares different strategies for keeping a specific blood pressure level during heart-lung bypass surgery. It may help reduce complications by finding the safest blood pressure target during the operation.
VeronaAges 18–80 - NCT06575530RecruitingPhase 4
Remimazolam for sedation after non-cardiac surgery
This trial tests a sedative called remimazolam besylate in patients who need a breathing tube and light sedation after non-cardiac surgery. The goal is to see if it works well and is safe.
Beijing, Beijing MunicipalityAges 18–64 - NCT04920565Recruiting
Hemoperfusion with Polymyxin B for septic shock after heart surgery
This trial studies a blood-filter treatment (hemoperfusion with Polymyxin B) to reduce harmful substances in the blood for people who develop septic shock after heart surgery. It may help by lowering inflammation and improving safety, but it also requires meeting specific signs of severe infection and blood/bleeding conditions.
MoscowAges 18–80 - NCT05812755RecruitingPhase 4
Study drug effects on blood vessels and organs in heart surgery
This Phase 4 trial studies vericiguat-like stimulation (a type of medicine that affects blood-vessel signaling) around the time of planned open-heart surgery. It aims to see whether this can change blood-vessel “reactivity” and reduce injury to organs during and after surgery.
Nashville, TennesseeAges 18 years+ - NCT07079904Recruiting
Laser and ultrasound for IV placement in heart surgery
This trial tests a new method using laser and ultrasound guidance to place a small tube (IV) in a vein for patients having heart surgery. It may help make the procedure faster and safer.
Nanjing, JiangsuAges 18–80 - NCT06823778Recruiting
Preventing irregular heartbeat after heart surgery with radiofrequency
This trial tests whether using radiofrequency energy to isolate a small area in the heart's left upper chamber can prevent a common irregular heartbeat (atrial fibrillation) after heart surgery.
Moscow, MoscowAges 18 years+ - NCT06716840Recruiting
Remimazolam for sedation after heart surgery
This trial tests a medication called Remimazolam Besylate to sedate patients who need a breathing tube after heart surgery. The goal is to help patients relax while they recover in the intensive care unit.
Hangzhou, ZhejiangAges 18 years+ - NCT06629311Recruiting
Blood recycling device study in heart surgery
This trial looks at how a device that collects and reuses your own blood during heart surgery works. It may help reduce the need for donated blood.
Strasbourg, Bas-RhinAges 18 years+ - NCT05635877RecruitingPhase 4
Low-dose heart-rate medicine after surgery in frail older adults
This trial tests whether a low dose of esmolol (a short-acting heart-rate medicine) can reduce heart muscle injury after non-heart surgery in older, frail people. It may help lower the chance of heart-related complications around the time of surgery.
Jinan, ShandongAges 65–90 - NCT06464263Recruiting
Dexmedetomidine vs. midazolam-fentanyl for sedation
This trial compares two sedation and pain relief medicine combinations (dexmedetomidine vs. midazolam-fentanyl) to see which works better for people having planned heart valve surgery.
CairoAges 21–50 - NCT05885230Recruiting
Pain relief after heart surgery: nerve block vs lidocaine drip
This trial compares two ways to manage pain after open-heart surgery: an ultrasound-guided nerve block (PIFB) versus lidocaine given through a vein. The goal is to see which method works better and helps you recover more comfortably.
Banī Suwayf, e\EYGPTAges 18–75 - NCT06405516Recruiting
Platelet function after heart surgery
This study watches how well platelets (cells that help blood clot) work in people who have high-risk heart surgery using a heart-lung machine for more than 2 hours. The goal is to learn more about bleeding risks after surgery.
BernAges 18 years+ - NCT07642765Recruiting
Frailty Score and Blood Pressure Changes During Surgery
This study looks at a simple scoring system (EASIX) that predicts whether older or frail patients will experience dangerous blood pressure drops when anesthesia is given before surgery. Understanding this risk might help doctors better protect vulnerable patients during their operations.
KonyaAges 18 years+ - NCT06324461RecruitingPhase 4
GLP-1 drug to protect heart after non-emergency surgery
This study tests whether a GLP-1 receptor agonist (a medication used for diabetes and weight loss) can reduce heart damage during or after planned non-cardiac surgery. It may help patients with heart risk undergoing intermediate to high-risk procedures.
Hong Kong, Hong Kong SARAges 18 years+ - NCT07611045Recruiting
Understanding recovery and care after heart surgery
This study asks patients and their families about their experience after heart surgery (like bypass or valve repair) to help doctors improve follow-up care. You'll share your story through an interview, and your feedback could help future patients.
Bristol, BristolAges 18 years+ - NCT06230198Recruiting
Effect of a blood-saving technique on transfusions after heart surgery
This trial tests whether a technique called retrograde autologous priming (using the patient's own blood to prepare the heart-lung machine) can reduce the need for blood transfusions during heart surgery. It is looking at hospitals and surgical teams, not individual patients, so it's not a typical trial you can join directly.
Winnipeg, ManitobaAges 10–110 - NCT07172620Recruiting
Heart bypass surgery without clamping the aorta
This study tests a special technique for heart bypass surgery that avoids clamping the aorta. It may help people with hardened arteries in the aorta who need bypass surgery but are not good candidates for standard clamping.
Beijing, Beijing MunicipalityAges Any age - NCT07593794Recruiting
Quality of Recovery After Heart Surgery Study
This study measures how well patients recover after planned heart surgery by having them answer questions about their physical and emotional wellbeing. The goal is to understand what affects recovery so doctors can better support patients afterward.
KocaeliAges 18 years+ - NCT06460519Recruiting
Comparing wrist and groin blood pressure in shock patients
This study looks at how blood pressure readings differ between the wrist and the groin in people with severe low blood pressure (shock) who are not recovering from heart surgery. It aims to help doctors better understand and treat shock by comparing these two measurements.
BronAges 18–99 - NCT07410988RecruitingPhase 4
Starch vs. crystalloid fluid for heart surgery patients
This trial compares two types of IV fluids (a starch solution vs. a balanced salt solution) to see which one better protects kidneys after heart surgery. It is for adults having planned heart surgery who do not have severe kidney problems.
DaejeonAges 19 years+ - NCT07287345RecruitingPhase 4
Colchicine’s effect on inflammation after heart bypass surgery
This trial tests whether the drug colchicine can reduce inflammation after planned coronary artery bypass graft (CABG) surgery. It may help patients recover better by lowering inflammatory markers.
Lexington, KentuckyAges 18–99 - NCT07179029Recruiting
Can anesthesia affect the heart during non-cardiac surgery?
This study looks at whether anesthesia can cause heart damage during non-cardiac surgeries. If you have certain health risks, participating may help doctors learn how to better protect your heart.
TübingenAges 40–80
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Common questions
- Are there clinical trials for cardiac surgery?
- Yes. Clin2 currently lists 310 recruiting cardiac surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.