Clinical trials
Cardiac Surgery clinical trials
Below are recruiting cardiac surgery clinical trials, each written for real people, not researchers. We’re tracking 310 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05824260Recruiting
Study of risk factors for complications after major surgery
This study looks at patients who've had major abdominal, bone, or blood-vessel surgery to understand what factors make some people more likely to have complications afterward. It analyzes information already collected from hospitals to help doctors better predict and prevent problems.
AmiensAges 18 years+ - NCT05841056RecruitingPhase 3
Short amiodarone treatment to prevent new heart rhythm after surgery
This trial studies whether a short course of amiodarone started right after heart surgery can reduce problems from new-onset atrial fibrillation (a common fast heart rhythm) or flutter. It may help some patients avoid ongoing rhythm issues and improve recovery soon after discharge.
Hamilton, OntarioAges 18 years+ - NCT06930443Recruiting
Oxygen use and organ injury after heart-lung bypass surgery
This trial looks at how oxygen is used during heart surgery that uses a heart-lung machine, and whether low oxygen levels can lead to organ damage. It may help doctors better understand how to protect patients during surgery.
Uppsala, SwedenAges 18 years+ - NCT06814951Recruiting
Breathing & movement technique after heart bypass surgery
This study tests a special breathing and movement technique called the Thoraco-abdominal Rebalance Method to see if it helps people recover faster after heart bypass surgery.
Porto Alegre, Rio Grande do SulAges 35 years+ - NCT06399536Recruiting
Individualized blood management for major non-cardiac surgery
This trial tests a personalized approach to managing your own blood during surgery, which may reduce the need for donor blood transfusions. It is for people having planned non-cardiac surgery expected to need a large amount of blood.
Chengdu, SichuanAges 18–75 - NCT06178510Recruiting
Breathing support after heart surgery
This trial tests a new way to help patients breathe after heart surgery. It compares standard breathing support with a new device that might help you recover faster in the ICU.
Vienna, State of ViennaAges 18–120 - NCT06128330RecruitingPhase 4
Bedside test for bleeding prevention drug in heart surgery
This study tests a quick bedside measurement of how well the drug tranexamic acid works to prevent bleeding during heart surgery. It may help doctors give the right dose to reduce blood loss.
BernAges 18–90 - NCT05481723RecruitingPhase 3
Lung ultrasound to guide fluid and blood pressure during surgery
This Phase 3 study tests whether using a lung ultrasound scan during surgery can better guide blood pressure and fluid needs. It may help stabilize patients during long operations and reduce complications related to poor circulation or fluid balance.
AmiensAges 18 years+ - NCT05944146Recruiting
Tests two methods for measuring heart blood flow during surgery
This trial compares a neck ultrasound test (carotid Doppler) with a heart monitoring method (thermodilution) to see if they give consistent blood-flow readings. It may help clinicians measure circulation more reliably in people having heart surgery.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07611890RecruitingPhase 4
Comparing two medications to reduce heart stress during cardiac surgery
This trial tests whether dexmedetomidine or lignocaine better prevents dangerous heart-rate and blood-pressure changes when a breathing tube is placed during heart surgery. If you're having cardiac surgery and are at high risk for heart complications, this study may help protect your heart during the procedure.
Rawalpindi, Punjab ProvinceAges 18–65 - NCT07533214Enrolling by invitation
Left-Handed Endoscopic Mitral Surgery Training Program
This trial tests a specialized training program designed specifically for left-handed surgeons learning minimally invasive heart valve surgery. The goal is to help left-handed surgeons develop the precise hand skills needed to perform these delicate procedures using specially adapted equipment and techniques.
PortugalAges Any age - NCT07386379Recruiting
Propofol infusion for nausea after heart bypass surgery
This study tests whether a continuous infusion of propofol (a common anesthesia medicine) during and after heart bypass surgery can reduce postoperative nausea and vomiting. If you are having planned bypass surgery and meet basic health criteria, this trial may help find a better way to feel more comfortable after your operation.
Istanbul, Outside of the USAges 18 years+ - NCT07173998Recruiting
Quality of life after heart surgery with irregular heartbeat
This study looks at quality of life in people who develop atrial fibrillation (an irregular heartbeat) after heart surgery. Researchers will ask you to fill out surveys to understand how this condition affects your daily life.
Boston, MassachusettsAges 18–100 - NCT07746505Recruiting
Remimazolam vs midazolam for anesthesia in older adults
This study compares two sedative medicines used to start general anesthesia in patients 65 and older having non-cardiac surgery. The goal is to see which one is safer and works better for older patients.
HangzhouAges 65 years+ - NCT07744009Recruiting
Awake breathing support for heart valve surgery
This trial tests a new anesthesia method that lets you breathe on your own during heart valve surgery, instead of using a breathing tube. It aims to see if this approach is safer and helps you recover faster than standard anesthesia.
Guangzhou, GuangdongAges 18 years+ - NCT07239648Recruiting
Heart surgery and confusion after the operation
This study looks at confusion or disorientation (delirium) that can happen after heart surgery. It aims to learn more about who might be affected and how to improve recovery.
Xi'an, ShaanxiAges 18 years+ - NCT07278661RecruitingPhase 2
Pre-surgery romiplostim for patients with low platelets having heart surgery
This trial tests if giving romiplostim before heart surgery can safely increase low platelet counts. It may help patients with low platelets avoid bleeding complications during and after surgery.
AngersAges 18 years+ - NCT03302195Recruiting
Heparin and bypass blood management for obese heart surgery
This trial studies the best way to manage blood thinning (anticoagulation) during heart surgery that uses a heart-lung machine in people with obesity. It may help reduce blood-clotting and bleeding complications by comparing different care strategies.
Québec, QuebecAges 18 years+ - NCT03546374Recruiting
Stop a common heart rhythm with surgery add-on therapy
This study looks at whether an added heart device approach around the time of planned open-heart surgery can help treat non-paroxysmal atrial fibrillation (AF), a long-lasting irregular heartbeat. It may help lower ongoing AF burden in people who also need non-emergency heart surgery.
Palo Alto, CaliforniaAges 18 years+ - NCT04164173Recruiting
Breathing therapies after heart surgery for lung overinflation
This study looks at breathing (respiratory) therapies to help after certain heart surgeries that can cause the lungs to feel overly inflated. If you’re eligible, you may receive and be assessed for how well these breathing treatments work during your recovery.
Dallas, TexasAges 18–80 - NCT04289142RecruitingPhase 4
Testing memory effects of dexmedetomidine during heart surgery
This study looks at how a sleep medicine called dexmedetomidine affects thinking and memory after heart surgery. It compares cognitive outcomes over time to see if this sedation choice changes long-term brain function.
Vancouver, British ColumbiaAges 60 years+ - NCT04299828Recruiting
Study of inflammation activity during complex heart surgery
This study measures how active white blood cells and inflammation are during complex heart surgery using a heart-lung machine. It may help doctors better understand what triggers inflammation during surgery and how to improve care.
Boston, MassachusettsAges Any age - NCT04707794Recruiting
Preventing confusion after non-heart surgery in older adults
This study looks at how often older adults develop sudden confusion (delirium) after non-heart operations under general anesthesia. It may help doctors better predict who is at risk and improve care after surgery.
New Delhi, National Capital Territory of DelhiAges 65 years+ - NCT04750616RecruitingPhase 2
NAD+ for heart injury prevention around non-emergency surgery
This Phase 2 trial studies whether adding NAD+ can reduce heart muscle injury around scheduled heart surgery. It may help protect the heart (and possibly kidneys) in people considered higher risk for complications.
San Francisco, CaliforniaAges 18 years+
Hear when a new Cardiac Surgery trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for cardiac surgery?
- Yes. Clin2 currently lists 310 recruiting cardiac surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.