Clinical trials
Cardiac Surgery clinical trials
Below are recruiting cardiac surgery clinical trials, each written for real people, not researchers. We’re tracking 295 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06728371RecruitingPhase 3
IV methadone for pain after heart surgery
This trial tests if methadone given through a vein can control pain better after heart surgery done through a breastbone incision. It may be an option for adults having planned heart surgery who are expected to wake up and breathe on their own within 12 hours.
Hong KongAges 18 years+ - NCT06730828RecruitingPhase 1/Phase 2
Amiodarone patch to prevent new irregular heartbeat after heart surgery
This trial tests a patch that releases amiodarone, a medicine that helps prevent a common irregular heartbeat after open-heart surgery. The patch is placed on the heart during surgery to stop new atrial fibrillation from starting.
Louisville, KentuckyAges 20–85 - NCT04808401Recruiting
Testing how different oxygen levels affect surgery outcomes
This trial studies whether giving higher or lower oxygen during general anesthesia changes heart and lung outcomes after planned (non-emergency) non-heart surgery. It may help doctors choose safer oxygen settings during surgery for people at higher risk for heart problems.
BernAges 18 years+ - NCT07556185Recruiting
Testing a home heart health monitoring app for kids
This study tests whether young people with heart conditions can use a home monitoring app called Medly to track their symptoms and weight. The app may help doctors catch problems earlier and keep kids healthier at home.
Toronto, OntarioAges 8–18 - NCT07557108Recruiting
Nerve Blocks to Improve Recovery After Heart Surgery
This study tests whether special numbing injections around nerves in the chest wall (fascial plane blocks) help patients recover better and have less pain after open-heart surgery. The goal is to see if this technique improves how you feel and function in the days after your operation.
Ordu, AltinorduAges 18–70 - NCT06361238RecruitingPhase 3
Liraglutide to prevent confusion after heart surgery in seniors with diabetes
This trial is testing if liraglutide, a diabetes medication, can prevent delirium (sudden confusion) in older adults with type 2 diabetes who are having planned heart surgery. If you qualify, you may help find a new way to protect brain function after surgery.
Nanjing, JiangsuAges 60 years+ - NCT07533214Enrolling by invitation
Left-Handed Endoscopic Mitral Surgery Training Program
This trial tests a specialized training program designed specifically for left-handed surgeons learning minimally invasive heart valve surgery. The goal is to help left-handed surgeons develop the precise hand skills needed to perform these delicate procedures using specially adapted equipment and techniques.
PortugalAges Any age - NCT07524998Recruiting
Surgery outcomes for complex heart defects across ages
This study tracks how children and adults with complex heart defects fare after surgery. Researchers want to understand what surgical techniques work best at different ages and how patients recover long-term.
BeijingAges Any age - NCT05353348Recruiting
Program to treat mild anemia around heart surgery
This trial tests a combined treatment plan to improve anemia (low blood count/iron levels) before and around the time of major elective heart surgery. It may help reduce the need for blood transfusions and support safer recovery.
Hangzhou, ZhejiangAges 18 years+ - NCT06775639Recruiting
Can we skip a heart artery test before surgery?
This study looks at whether people with adult congenital heart disease can skip a pre-surgery artery test (coronary angiography) if they already had a CT scan. If you qualify, you might help doctors find safer, simpler ways to prepare for heart surgery.
BolognaAges 18 years+ - NCT06790277Recruiting
Foam cushion study for heart surgery patients
This trial tests a special foam cushion for heart surgery patients, to see if it helps prevent pressure sores. You may be able to join if you are at risk for pressure sores but do not have any yet.
Mecca, Western ReaganAges 18 years+ - NCT06258681Recruiting
Breathing exercise device for recovery after heart surgery
This trial tests a new breathing exercise device designed to help your lungs recover after heart surgery. It may make your breathing easier and speed up your return to daily activities.
Istanbul, IstanbulAges 40–65 - NCT06778811RecruitingPhase 4
Sleep quality study for heart surgery patients
This trial studies sleep problems before and after heart surgery. It tests two medicines to see if they can help improve sleep. This may help you recover better after surgery.
Nanjing, JiangsuAges 40–75 - NCT07422129Recruiting
Aortic wall analysis during heart surgery
This study looks at the structure and strength of the aorta (the main artery from your heart) in patients having surgery to replace part of it or having a heart transplant. The goal is to better understand the aortic wall to improve future treatments.
Pavia, LombardyAges 18 years+ - NCT07410988RecruitingPhase 4
Starch vs. crystalloid fluid for heart surgery patients
This trial compares two types of IV fluids (a starch solution vs. a balanced salt solution) to see which one better protects kidneys after heart surgery. It is for adults having planned heart surgery who do not have severe kidney problems.
DaejeonAges 19 years+ - NCT07414251Recruiting
Preparing children for heart procedures
This study looks at how children prepare for heart surgery or a heart catheterization. It will ask families to fill out questionnaires to help improve preoperative care.
Berlin, State of BerlinAges Up to 18 years - NCT07401836Recruiting
Sleep bundle for heart surgery patients
This trial tests a special sleep program (bundle) to help patients sleep better after heart surgery. Researchers want to see if it improves recovery and well-being.
Saint John, New BrunswickAges 19 years+ - NCT06716840Recruiting
Remimazolam for sedation after heart surgery
This trial tests a medication called Remimazolam Besylate to sedate patients who need a breathing tube after heart surgery. The goal is to help patients relax while they recover in the intensive care unit.
Hangzhou, ZhejiangAges 18 years+ - NCT07386379Recruiting
Propofol infusion for nausea after heart bypass surgery
This study tests whether a continuous infusion of propofol (a common anesthesia medicine) during and after heart bypass surgery can reduce postoperative nausea and vomiting. If you are having planned bypass surgery and meet basic health criteria, this trial may help find a better way to feel more comfortable after your operation.
Istanbul, Outside of the USAges 18 years+ - NCT05886517Recruiting
Transcatheter aortic valve in patients too high-risk for surgery
This trial looks at placing a new aortic valve through the groin (transfemoral) without needing on-site heart surgery for people who are considered very high risk for standard open-heart valve surgery. It aims to measure early outcomes to see how safe and effective this approach is for frail or complex patients.
Acquaviva delle Fonti, BariAges 75–120 - NCT06823778Recruiting
Preventing irregular heartbeat after heart surgery with radiofrequency
This trial tests whether using radiofrequency energy to isolate a small area in the heart's left upper chamber can prevent a common irregular heartbeat (atrial fibrillation) after heart surgery.
Moscow, MoscowAges 18 years+ - NCT06230198Recruiting
Effect of a blood-saving technique on transfusions after heart surgery
This trial tests whether a technique called retrograde autologous priming (using the patient's own blood to prepare the heart-lung machine) can reduce the need for blood transfusions during heart surgery. It is looking at hospitals and surgical teams, not individual patients, so it's not a typical trial you can join directly.
Winnipeg, ManitobaAges 10–110 - NCT07351149Recruiting
Study on kidney injury after major surgery in children
This trial looks at how often children develop kidney problems after major surgery that isn't on the heart or kidneys. The goal is to learn more about these injuries and how to prevent them.
Perth, Western AustraliaAges birth–16 years - NCT04750616RecruitingPhase 2
NAD+ for heart injury prevention around non-emergency surgery
This Phase 2 trial studies whether adding NAD+ can reduce heart muscle injury around scheduled heart surgery. It may help protect the heart (and possibly kidneys) in people considered higher risk for complications.
San Francisco, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for cardiac surgery?
- Yes. Clin2 currently lists 295 recruiting cardiac surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.