Clinical trials
Cartilage Defects of the Knee clinical trials
Below are recruiting cartilage defects of the knee clinical trials, each written for real people, not researchers. We’re tracking 16 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07639424RecruitingPhase 4
New cartilage regeneration treatment for knee repair
This study tests a new platform to help repair damaged knee cartilage. If your knee has a specific type of cartilage damage, this treatment might help restore function and reduce pain.
Daegu, DaeguAges 19–64 - NCT07575555Recruiting
Lipedema's role in knee arthritis in women
This study compares women with knee arthritis who do or don't have lipedema (a condition causing painful fat buildup, usually in the legs) to understand how lipedema affects knee joint health. Results may help doctors better treat knee arthritis in women with lipedema.
Izmir, İzmirAges 30–65 - NCT07339111RecruitingPhase 3
CARTISTEM vs surgery for knee cartilage damage and osteoarthritis
This trial tests if a cell-based treatment called CARTISTEM can repair knee cartilage better than surgery alone. It involves people with knee osteoarthritis and a cartilage defect, with moderate pain and limited function.
Birmingham, AlabamaAges 18–75 - NCT07094100Recruiting
Repairing knee cartilage with lab-grown tissue
This study tests whether lab-made cartilage can safely and effectively repair knee joint damage in adults. It may be an option if you have a cartilage defect from an injury or other cause and haven't had recent knee surgery.
Xinxiang, HenanAges 18–65 - NCT06915363Recruiting
BioPoly implant for knee cartilage repair
This trial tests a BioPoly implant to repair a small damaged cartilage spot in your knee. If you have a specific type of cartilage injury that didn't get better with other treatments, this implant may help relieve pain and improve function.
Fort Wayne, IndianaAges 30–65 - NCT06893302Recruiting
Bone marrow injection during knee scope for cartilage or meniscus
This trial tests if adding a bone marrow injection to standard knee arthroscopy helps your knee heal better. It is for people with a torn meniscus or damaged cartilage who have healthy knee joints without arthritis.
New York, New YorkAges 18–64 - NCT03588975RecruitingPhase 3
Cartilage repair for knee damage in teens
This trial tests two ways to repair damaged knee cartilage in young people: one uses your own cartilage cells grown in a lab (MACI), and the other is a standard procedure called microfracture. The goal is to see which works better to reduce pain and improve knee function, and to help you get back to normal activities.
Palo Alto, CaliforniaAges 10–17 - NCT02503228Enrolling by invitation
Registry study of a preserved bone-cartilage graft
This registry study follows people who get a preserved graft to repair damaged bone and cartilage in a joint. It helps doctors understand how well the graft is preserved and how patients do after surgery over time.
Columbia, MissouriAges 13 years+ - NCT04744402RecruitingPhase 2
Cartilage repair treatment test for knee joint damage
This Phase 2 study tests CartiLife® to help repair a specific type of damaged knee cartilage. You may be considered if you have a moderate-sized cartilage defect in the knee and enough pain and function limits to need treatment.
Irvine, CaliforniaAges 18 years+ - NCT06981741RecruitingPhase 1/Phase 2
Stem cell treatment for knee cartilage damage
This trial tests whether a new stem cell treatment, given during a surgical procedure, can help repair damaged cartilage in the knee. It is for people with moderate to severe knee pain and a specific size of cartilage injury.
AltenburgAges 18–60 - NCT06249906Recruiting
Bioceramic material for bone defect repair
This trial tests a new bioceramic material to repair bone defects. It is for adults aged 18 to 65 who are generally healthy and can follow the study plan.
Nanjing, JiangsuAges 18–65 - NCT05942430Recruiting
Bone-cartilage transplant for ankle joint cartilage damage
This trial studies an “autologous” transplant, meaning using your own bone and cartilage, to treat painful cartilage damage in the ankle (on the talus). It may help people whose ankle cartilage injury is deep, has not improved with non-surgical care, and meets specific side and health requirements.
Guangzhou, GuangdongAges 18–60 - NCT06368700Recruiting
Testing a new knee cartilage implant (HYALEX)
This study is testing a new implant called HYALEX to repair cartilage damage in the knee. It may help people with painful knee cartilage defects that haven't gotten better with other treatments like physical therapy or injections.
La Mesa, CaliforniaAges 22–70 - NCT07491367RecruitingPhase 4
Platelet-rich plasma for knee osteoarthritis
This study tests two different ways of preparing platelet-rich plasma (a treatment made from your own blood) to see which one works better for knee osteoarthritis. You'll also do physical therapy as part of the study.
San Francisco, CaliforniaAges 18 years+ - NCT06216756Recruiting
Frozen cartilage transplant for knee cartilage defects
This trial tests a frozen cartilage transplant (called an osteochondral allograft) for people with painful knee cartilage defects. It aims to see if this procedure can help relieve pain and improve knee function.
Phoenix, ArizonaAges 12–60 - NCT04236492Recruiting
Fresh cartilage graft study for large knee joint damage
This trial studies how well a fresh cartilage and bone graft works to repair large, full-thickness defects in the knee. It also looks at imaging results (pictures of the knee) to see how the repair is healing over time.
Barcelona, CataloniaAges 15–50
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Common questions
- Are there clinical trials for cartilage defects of the knee?
- Yes. Clin2 currently lists 16 recruiting cartilage defects of the knee studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cartilage defects of the knee trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cartilage defects of the knee trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.