Clinical trials
Central Sleep Apnea clinical trials
Below are recruiting central sleep apnea clinical trials, each written for real people, not researchers. We’re tracking 98 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06681974RecruitingPhase 3
Throat therapy for sleep apnea without CPAP
This trial tests a type of mouth and throat therapy to see if it can help people with mild to moderate sleep apnea who can't or don't want to use a CPAP machine. It might be an option if you want a non-machine treatment for your sleep apnea.
SantanderAges 18–70 - NCT07277608Recruiting
Study on sleep apnea patients and their health over time
This study looks at patients with suspected or confirmed obstructive sleep apnea (a condition where breathing stops and starts during sleep) to understand the condition better. Researchers will follow patients for at least one year to learn more about the underlying causes and how it affects health.
Beijing, Beijing MunicipalityAges Any age - NCT07427589Recruiting
New Heart Tests in Sleep Apnea
This study looks at how sleep apnea affects your heart and blood vessels over time. It uses a sleep study and heart tests to see if certain measurements can predict heart health changes.
AntwerpAges 18 years+ - NCT05147649Recruiting
Brain scan study in severe sleep apnea without CPAP
This trial uses a specialized brain scan (MRI) to study people with severe obstructive sleep apnea who are not using CPAP. It also compares them with people who do not have sleep apnea to understand how brain function differs.
ReimsAges 18–75 - NCT05539716Recruiting
Treating sleep apnea to study effects on metabolism
This study tests a sleep apnea treatment approach and looks at how it may affect your body’s metabolism. You may be eligible if you’re an adult with sleep apnea and meet health and medication rules, and possibly if you already use a PAP machine regularly.
Miami, FloridaAges 18–70 - NCT02703220RecruitingPhase 4
Finasteride test for mild to moderate sleep apnea in seniors
This study looks at whether finasteride (a prescription medicine) can help older adults with mild to moderate sleep apnea. You may be screened with a sleep test to confirm your breathing pattern during sleep.
Detroit, MichiganAges 60–89 - NCT05612594RecruitingPhase 4
Study of an SGLT2 pill for sleep apnea in overweight adults
This study tests whether taking an SGLT2 inhibitor pill (bexagliflozin) can improve obstructive sleep apnea and related body measurements. It focuses on people who are overweight or obese and have confirmed obstructive sleep apnea.
New Haven, ConnecticutAges 18 years+ - NCT05939934Recruiting
Test a mouth device for sleep apnea after stopping CPAP
This study looks at whether a mandibular advancement device (a fitted mouthpiece) can control sleep apnea when you temporarily stop CPAP. It’s mainly for people who have been using CPAP for over a year but are now willing to try the mouth device.
AngersAges 18–75 - NCT06514482Recruiting
Spanish sleep apnea and daytime sleepiness registry
This study will collect information from people with suspected sleep apnea who feel very sleepy during the day. If you are 18 or older and about to have a sleep study, you may be able to help researchers learn more about this condition.
Logroño, La RiojaAges 18 years+ - NCT06801366Recruiting
Video clips to help diagnose sleep apnea in children
This study tests if video clips recorded at home can help diagnose obstructive sleep apnea in children, possibly reducing the need for an overnight hospital sleep test. It may be a good fit if your child is between 2 and 18 years old, has been referred for a sleep study, and you have a smartphone or tablet.
Edmonton, AlbertaAges 2–18 - NCT07082608Recruiting
Weight loss procedure plus lifestyle changes for sleep apnea
This study tests whether a stomach procedure called endoscopic sleeve gastroplasty (ESG) plus lifestyle changes helps people with sleep apnea lose more weight and improve their breathing compared to lifestyle changes alone. If you have moderate to severe sleep apnea and have struggled to lose weight, this may be an option.
Hyderabad, TelanganaAges 18 years+ - NCT02919930Recruiting
Testing a new breathing support choice for central sleep apnea
This study looks at which settings to use for adaptive servo-ventilation (ASV), a machine that helps breathing during sleep. It is meant for people with central sleep apnea who are not getting enough benefit from CPAP, so ASV may be a better match.
LeuvenAges 18 years+ - NCT06974851RecruitingPhase 3
Study of HRS9531 for sleep apnea and obesity
This trial tests an injectable medication (HRS9531) to see if it helps people with both obstructive sleep apnea and obesity. It compares the drug to a placebo (no active medicine) to check safety and effectiveness.
Beijing, Beijing MunicipalityAges 18–75 - NCT06283095Recruiting
Expanding the palate to help sleep apnea
This surgery expands the palate to treat obstructive sleep apnea caused by a narrow upper airway. It may help people with mild to moderate sleep apnea who have a specific type of airway collapse seen on a sleep-endoscopy test.
AsyutAges 18–70 - NCT04903951RecruitingPhase 2
Check if early breathing support after stroke helps sleep apnea
This trial tests whether starting a breathing-support treatment soon after a first stroke improves outcomes in people who also have sleep apnea. It may help reduce complications and support recovery if you meet the specific timing and health criteria.
Matosinhos MunicipalityAges 18–80 - NCT05237505RecruitingPhase 2
Sleep apnea plus COPD study to check heart and breathing effects
This Phase 2 study looks at the cardiovascular (heart/blood vessel) effects of having both sleep apnea and COPD. It may help doctors better understand who is at risk and how to manage these breathing problems together.
La Jolla, CaliforniaAges 40–79 - NCT06103630Recruiting
Mouth exercises for sleep apnea with mouthguard therapy
This study tests whether specific mouth and throat exercises can help people with sleep apnea who already use a mandibular advancement device (a type of mouthguard). The goal is to see if adding exercises improves sleep and breathing.
TainanAges 20 years+ - NCT06512779Recruiting
Sleep apnea treatment clustering study
This study looks at sleep recordings to group people with obstructive sleep apnea based on their unique signals. The goal is to match each person to the best treatment for them.
TainanAges 20 years+ - NCT06608888Recruiting
Brain chemical study for sleep apnea and snoring
This study looks at how a brain chemical called 5-HT7 affects sleep apnea by testing different groups: people with sleep apnea, people who snore, and healthy volunteers. It aims to find new ways to help regulate breathing during sleep.
Beijing, Beijing MunicipalityAges 20–60 - NCT07464262Recruiting
Telemonitoring with CPAP for severe sleep apnea patients
This trial tests whether telemonitoring (checking in remotely) helps people with severe sleep apnea adjust to CPAP therapy. If you live in São Paulo and recently started CPAP, this study may help you get extra support.
São Paulo, São PauloAges 18–75 - NCT05558501RecruitingPhase 1/Phase 2
Intermittent low-oxygen therapy for sleep apnea and health risks
This early-stage study tests a treatment that briefly reduces oxygen during sleep to improve “plasticity,” with the goal of helping people with obstructive or mixed sleep apnea. It also looks at related conditions like high blood pressure and pre-diabetes or cholesterol problems, especially in people who haven’t tried CPAP yet.
Detroit, MichiganAges 30–60 - NCT06317701Recruiting
Nerve stimulation for sleep apnea in overweight adults
This trial tests a nerve stimulation treatment for obstructive sleep apnea in people who are overweight and cannot tolerate CPAP. It focuses on how the treatment affects metabolism and weight.
Chicago, IllinoisAges 18 years+ - NCT06698809Recruiting
Treating leftover sleepiness in sleep apnea patients
This study tests if a light therapy device can help reduce daytime sleepiness in people who are already using a CPAP machine for sleep apnea but still feel tired. It involves MRI scans and regular check-ins over two years.
New York, New YorkAges 18–75 - NCT06834724Recruiting
CPAP for sleep apnea and chronic pain
This study looks at whether CPAP treatment improves pain and daily life in people who have both sleep apnea and chronic pain. It tests if starting CPAP for the first time can help these symptoms.
BrusselsAges 18 years+
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Common questions
- Are there clinical trials for central sleep apnea?
- Yes. Clin2 currently lists 98 recruiting central sleep apnea studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a central sleep apnea trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a central sleep apnea trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.