Clinical trials
Central Sleep Apnea clinical trials
Below are recruiting central sleep apnea clinical trials, each written for real people, not researchers. We’re tracking 94 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06189755Recruiting
MicroRNA markers for sleep apnea
This trial is studying tiny molecules in the blood (called microRNAs) to see if they can help diagnose or monitor obstructive sleep apnea. It compares people with moderate to severe sleep apnea who are starting PAP therapy with people who do not have sleep apnea.
Columbus, OhioAges 18–75 - NCT04118387RecruitingPhase 4
Study of how to treat central sleep apnea in Veterans
This Phase 4 study looks at what’s going on in the body during central sleep apnea and uses that information to guide treatment. If you have central sleep apnea, this could help confirm or improve how treatment is chosen for you.
Detroit, MichiganAges 18 years+ - NCT07679282RecruitingPhase 4
Comparing sleep apnea treatments: CPAP, mouthpiece, or medication
This study compares three treatments for obstructive sleep apnea: a CPAP machine, a dental mouthpiece, and a combination of two medications (atomoxetine and oxybutynin). Researchers want to see which works best for people recently diagnosed with sleep apnea.
Tucson, ArizonaAges 18 years+ - NCT05147649Recruiting
Brain scan study in severe sleep apnea without CPAP
This trial uses a specialized brain scan (MRI) to study people with severe obstructive sleep apnea who are not using CPAP. It also compares them with people who do not have sleep apnea to understand how brain function differs.
ReimsAges 18–75 - NCT05539716Recruiting
Treating sleep apnea to study effects on metabolism
This study tests a sleep apnea treatment approach and looks at how it may affect your body’s metabolism. You may be eligible if you’re an adult with sleep apnea and meet health and medication rules, and possibly if you already use a PAP machine regularly.
Miami, FloridaAges 18–70 - NCT02703220RecruitingPhase 4
Sleep apnea treatment in older adults
This study tests whether certain medications can help older adults with mild to moderate sleep apnea breathe better during sleep. It aims to improve sleep quality and safety for elderly patients.
Detroit, MichiganAges 60–89 - NCT07082608Recruiting
Weight loss procedure plus lifestyle changes for sleep apnea
This study tests whether a stomach procedure called endoscopic sleeve gastroplasty (ESG) plus lifestyle changes helps people with sleep apnea lose more weight and improve their breathing compared to lifestyle changes alone. If you have moderate to severe sleep apnea and have struggled to lose weight, this may be an option.
Hyderabad, TelanganaAges 18 years+ - NCT06801366Recruiting
Video clips to help diagnose sleep apnea in children
This study tests if video clips recorded at home can help diagnose obstructive sleep apnea in children, possibly reducing the need for an overnight hospital sleep test. It may be a good fit if your child is between 2 and 18 years old, has been referred for a sleep study, and you have a smartphone or tablet.
Edmonton, AlbertaAges 2–18 - NCT06514482Recruiting
Spanish sleep apnea and daytime sleepiness registry
This study will collect information from people with suspected sleep apnea who feel very sleepy during the day. If you are 18 or older and about to have a sleep study, you may be able to help researchers learn more about this condition.
Logroño, La RiojaAges 18 years+ - NCT05939934Recruiting
Test a mouth device for sleep apnea after stopping CPAP
This study looks at whether a mandibular advancement device (a fitted mouthpiece) can control sleep apnea when you temporarily stop CPAP. It’s mainly for people who have been using CPAP for over a year but are now willing to try the mouth device.
AngersAges 18–75 - NCT05612594RecruitingPhase 4
Study of an SGLT2 pill for sleep apnea in overweight adults
This study tests whether taking an SGLT2 inhibitor pill (bexagliflozin) can improve obstructive sleep apnea and related body measurements. It focuses on people who are overweight or obese and have confirmed obstructive sleep apnea.
New Haven, ConnecticutAges 18 years+ - NCT06974851RecruitingPhase 3
Study of HRS9531 for sleep apnea and obesity
This trial tests an injectable medication (HRS9531) to see if it helps people with both obstructive sleep apnea and obesity. It compares the drug to a placebo (no active medicine) to check safety and effectiveness.
Beijing, Beijing MunicipalityAges 18–75 - NCT06283095Recruiting
Expanding the palate to help sleep apnea
This surgery expands the palate to treat obstructive sleep apnea caused by a narrow upper airway. It may help people with mild to moderate sleep apnea who have a specific type of airway collapse seen on a sleep-endoscopy test.
AsyutAges 18–70 - NCT06103630Recruiting
Mouth exercises for sleep apnea with mouthguard therapy
This study tests whether specific mouth and throat exercises can help people with sleep apnea who already use a mandibular advancement device (a type of mouthguard). The goal is to see if adding exercises improves sleep and breathing.
TainanAges 20 years+ - NCT06608888Recruiting
Brain chemical study for sleep apnea and snoring
This study looks at how a brain chemical called 5-HT7 affects sleep apnea by testing different groups: people with sleep apnea, people who snore, and healthy volunteers. It aims to find new ways to help regulate breathing during sleep.
Beijing, Beijing MunicipalityAges 20–60 - NCT07464262Recruiting
Telemonitoring with CPAP for severe sleep apnea patients
This trial tests whether telemonitoring (checking in remotely) helps people with severe sleep apnea adjust to CPAP therapy. If you live in São Paulo and recently started CPAP, this study may help you get extra support.
São Paulo, São PauloAges 18–75 - NCT05237505RecruitingPhase 2
Sleep apnea plus COPD study to check heart and breathing effects
This Phase 2 study looks at the cardiovascular (heart/blood vessel) effects of having both sleep apnea and COPD. It may help doctors better understand who is at risk and how to manage these breathing problems together.
La Jolla, CaliforniaAges 40–79 - NCT06834724Recruiting
CPAP for sleep apnea and chronic pain
This study looks at whether CPAP treatment improves pain and daily life in people who have both sleep apnea and chronic pain. It tests if starting CPAP for the first time can help these symptoms.
BrusselsAges 18 years+ - NCT06698809Recruiting
Treating leftover sleepiness in sleep apnea patients
This study tests if a light therapy device can help reduce daytime sleepiness in people who are already using a CPAP machine for sleep apnea but still feel tired. It involves MRI scans and regular check-ins over two years.
New York, New YorkAges 18–75 - NCT06317701Recruiting
Nerve stimulation for sleep apnea in overweight adults
This trial tests a nerve stimulation treatment for obstructive sleep apnea in people who are overweight and cannot tolerate CPAP. It focuses on how the treatment affects metabolism and weight.
Chicago, IllinoisAges 18 years+ - NCT05558501RecruitingPhase 1/Phase 2
Intermittent low-oxygen therapy for sleep apnea and health risks
This early-stage study tests a treatment that briefly reduces oxygen during sleep to improve “plasticity,” with the goal of helping people with obstructive or mixed sleep apnea. It also looks at related conditions like high blood pressure and pre-diabetes or cholesterol problems, especially in people who haven’t tried CPAP yet.
Detroit, MichiganAges 30–60 - NCT02431507Recruiting
First test of an implant device to prevent sleep apnea pauses
This trial is testing whether a new implanted device is safe and feasible for people with moderate to severe obstructive sleep apnea. It may help if you cannot tolerate CPAP (a common breathing device) and your apnea is caused by airflow blockage at the back of the tongue area.
San Francisco, CaliforniaAges 21–70 - NCT06789770Recruiting
Nasal vs mouth breathing during drug-induced sleep
This study compares how breathing through the nose versus mouth affects sleep, using both natural and medication-induced sleep. It may help people with sleep apnea understand their breathing patterns better.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07434050RecruitingPhase 3
Study of XW003 for obesity with sleep apnea on CPAP therapy
This trial tests an investigational drug called XW003 to see if it helps people with obesity and obstructive sleep apnea who are already using a positive airway pressure (PAP) machine, like CPAP. It aims to improve weight loss and sleep apnea symptoms.
Shanghai, Shanghai MunicipalityAges 18–75
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Common questions
- Are there clinical trials for central sleep apnea?
- Yes. Clin2 currently lists 94 recruiting central sleep apnea studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a central sleep apnea trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a central sleep apnea trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.