Clinical trials
Children, Adult clinical trials
Below are recruiting children, adult clinical trials, each written for real people, not researchers. We’re tracking 184 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07441707RecruitingPhase 1
Tovorafenib for Japanese children and young adults with brain tumors
This study tests an experimental medicine called tovorafenib for children and young adults (6 months to 25 years) with Japanese ancestry whose low-grade brain tumors have returned or grown after prior treatment. The medicine targets tumors with a specific BRAF genetic change.
KanagawaAges 6 months–25 years - NCT06926894RecruitingPhase 1
A cell therapy for viral infections in children and young adults
This trial tests a special immune cell treatment (R-MVST cells) for children and young adults who have had a stem cell or organ transplant and are fighting stubborn viral infections like EBV, CMV, ADV, or BK virus. The goal is to see if these cells can help control the viruses when standard medicines haven't worked well enough.
New York, New YorkAges 3 months–26 years - NCT07297979RecruitingPhase 1
Xaluritamig for relapsed or refractory Ewing sarcoma
This trial is testing a new drug called xaluritamig for children, teens, and adults with Ewing sarcoma that has come back or is not responding to treatment. The goal is to see if this drug can shrink the cancer or stop it from growing.
Los Angeles, CaliforniaAges 2 years+ - NCT03779854RecruitingPhase 2
Preventing graft-versus-host disease in kids after stem cell transplant
This trial tests whether removing certain immune cells (T cells) from the donor transplant can lower the risk of chronic graft-versus-host disease (long-term immune attack after transplant) in children and young adults with blood cancers. If you qualify, it may help improve transplant outcomes while tracking safety and side effects.
Los Angeles, CaliforniaAges 6 months–26 years - NCT03983369RecruitingPhase 3
Laser treatment to help prevent painful mouth sores from chemo
This trial tests whether low-level laser therapy (using special light on the mouth) can prevent or reduce mouth sores caused by chemotherapy in children and young adults. It may help you avoid painful inflammation that can affect eating, comfort, and treatment.
Villejuif, Val de MarneAges 4–25 - NCT04209244Recruiting
Fish oil for cholesterol and side effects in ALL patients
This trial studies whether fish oil can improve cholesterol levels and reduce side effects in children and young adults with acute lymphoblastic leukemia (ALL) who are in lower-risk groups. If you fit the risk category, you may be asked to add fish oil as part of the study to see if it helps your lab results and well-being.
AalborgAges 1–45 - NCT04249830Recruiting
Donor stem cell transplant after donor cell targeting in youth
This trial studies a special donor stem cell transplant where the donor’s immune cells are reduced, aiming to lower harmful immune attacks after transplant. It may help children and young adults with certain high-risk blood cancers or rare bone marrow disorders.
Palo Alto, CaliforniaAges 1 month–60 years - NCT04644016RecruitingPhase 2
Cord blood transplant for children and young adults with blood cancers
This Phase 2 trial studies using a cord blood transplant after finding it is risky enough that standard treatment may not be sufficient. It may help certain children and young adults with specific leukemia, lymphoma, and some non-cancer blood/immune or inherited disorders who do not have a well-matched donor available in time.
New York, New YorkAges Up to 21 years - NCT04684368RecruitingPhase 2
New treatment study for children and young adults with NGGCT brain tumors
This Phase 2 study tests a new treatment approach for certain brain tumors called NGGCT in children and young adults. It may help improve outcomes by targeting tumors in specific brain locations and using tumor marker tests to guide care.
Birmingham, AlabamaAges 3–29 - NCT04928677RecruitingPhase 1
Codrituzumab for children and young adults with GPC3-positive solid tumors
This Phase 1 study tests codrituzumab, an antibody medicine, in children and young adults whose solid tumor has come back or did not respond to standard treatment. It’s designed to see how the treatment works and how safe it is, especially for tumors that test positive for GPC3.
Los Angeles, CaliforniaAges 1–21 - NCT04971850Recruiting
Sleep study for children with possible breathing sleep problems
This trial looks at sleep-related breathing problems (“sleep-disordered breathing”) in children and young adults and how they may affect thinking and memory using sleep study testing plus neurocognitive (thinking) assessments. It may help doctors better understand symptoms and identify who could benefit from treatment.
ParisAges 1–20 - NCT05004116RecruitingPhase 1/Phase 2
Repotrectinib plus chemotherapy for relapsed solid tumors in youth
This early-phase study tests repotrectinib (a targeted anti-cancer pill) combined with chemotherapy in children and young adults whose solid tumors have come back or did not respond to standard treatment. The goal is to see how safe the treatment is and whether it can shrink tumors.
New York, New YorkAges 1–25 - NCT05237986Recruiting
Study brain and thinking effects after CAR T therapy in youth
This study looks at how CAR T-cell treatment affects thinking, learning, and day-to-day brain function in children and young adults with certain blood cancers. You (and a caregiver) may complete online testing so researchers can track these changes over time and whether support is needed.
Los Angeles, CaliforniaAges 5 years+ - NCT05419960Recruiting
Hearing and balance testing for teens with osteogenesis imperfecta
This study checks how well the inner ear and balance system work in children and young adults with osteogenesis imperfecta (OI). The goal is to better understand hearing and balance issues that can affect daily life.
ParisAges 12–20 - NCT05442515RecruitingPhase 1/Phase 2
CAR T-cell treatment for hard-to-treat B-cell cancers in youth
This trial tests a personalized immune-cell therapy (CAR T cells) made to attack B-cell cancers that have come back or did not respond to prior treatment. It aims to see how well the treatment works and how safe it is in children and young adults.
Bethesda, MarylandAges 3–39 - NCT05465174RecruitingPhase 2
Tovorafenib for children and young adults with craniopharyngioma
This trial studies tovorafenib to treat craniopharyngioma in children and young adults. It aims to shrink the tumor or slow its growth, and to learn which patients benefit most and what side effects to expect.
Birmingham, AlabamaAges 1–39 - NCT05638724Recruiting
Long COVID health registry for people of all ages
This study builds a health registry to learn how long COVID affects children, teens, and adults over time. It may help by improving understanding of symptoms and care, even if it does not test a new drug.
Munich, BavariaAges Any age - NCT05785533Recruiting
Mobile app for recovery after recent ankle sprains
This trial tests whether a smartphone “recovery guidance” app can help children and young adults heal after a recent ankle inversion injury. It may help with home recovery steps and decision-making during the first days after injury.
London, OntarioAges 12–30 - NCT05796570RecruitingPhase 2
Decitabine plus filgrastim to prevent relapse after transplant
This trial tests whether giving decitabine with filgrastim soon after a stem cell transplant can be done safely and may help prevent the leukemia or related cancer from coming back. It is aimed at children and young adults with AML, MDS, or related myeloid cancers.
Boston, MassachusettsAges 1–39 - NCT06122675Recruiting
Deep brain stimulation for movement problems in children with cerebral palsy
This study tests whether deep brain stimulation (a small device placed in the brain that sends electrical pulses) can help improve movement problems in children and young adults with a certain type of cerebral palsy. The goal is to see if it can reduce involuntary movements like twisting or jerking.
San Francisco, CaliforniaAges 7–25 - NCT06305910RecruitingPhase 1
Vaccine immunotherapy for recurrent brain tumors or newly diagnosed DIPG
This trial tests a combination of a vaccine made from tumor cells and a drug that may boost the immune system's ability to fight brain tumors. It is for children and young adults with a recurrent high-grade glioma or a newly diagnosed diffuse midline glioma with a specific genetic marker (H3K27M).
Minneapolis, MinnesotaAges 2–25 - NCT06306196RecruitingPhase 2
Hepatitis E vaccine study in healthy adults, children, and people with HIV
This study tests a hepatitis E vaccine called Hecolin in healthy people (ages 2–45) and in adults (18–45) living with HIV who are on antiviral treatment. It aims to see how well the vaccine works and if it's safe for different groups.
Ga-RankuwaAges 2–45 - NCT06498596Recruiting
New ways to study movement in kids with movement disorders
This study tests new ways to measure movement (like walking and joint motion) in children and young adults. It's for people with cerebral palsy and healthy volunteers, to better understand movement differences.
Bethesda, MarylandAges 5–25 - NCT06756152RecruitingPhase 2/Phase 3
Preventing GVHD after transplant for blood cancers in children and young adults
This trial tests a combination of four medicines (cyclophosphamide, abatacept, vedolizumab, and ruxolitinib) to prevent graft-versus-host disease (GVHD) after a stem cell transplant for children and young adults with certain blood cancers. The goal is to see if this approach reduces the risk of GVHD, a serious complication where donor cells attack the body.
MoscowAges 1 day–21 years
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Common questions
- Are there clinical trials for children, adult?
- Yes. Clin2 currently lists 184 recruiting children, adult studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a children, adult trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a children, adult trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.