Clinical trials
Children, Adult clinical trials
Below are recruiting children, adult clinical trials, each written for real people, not researchers. We’re tracking 180 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05419960Recruiting
Hearing and balance testing for teens with osteogenesis imperfecta
This study checks how well the inner ear and balance system work in children and young adults with osteogenesis imperfecta (OI). The goal is to better understand hearing and balance issues that can affect daily life.
ParisAges 12–20 - NCT06122675Recruiting
Deep brain stimulation for movement problems in children with cerebral palsy
This study tests whether deep brain stimulation (a small device placed in the brain that sends electrical pulses) can help improve movement problems in children and young adults with a certain type of cerebral palsy. The goal is to see if it can reduce involuntary movements like twisting or jerking.
San Francisco, CaliforniaAges 7–25 - NCT05999994RecruitingPhase 2
Testing new drugs for children and young adults with cancer
This trial tests several experimental drugs for children and young adults with cancer. It aims to find safe and effective treatments by matching participants to one of several drug studies based on their cancer type and health.
Birmingham, AlabamaAges 1–39 - NCT05465174RecruitingPhase 2
Tovorafenib for children and young adults with craniopharyngioma
This trial studies tovorafenib to treat craniopharyngioma in children and young adults. It aims to shrink the tumor or slow its growth, and to learn which patients benefit most and what side effects to expect.
Birmingham, AlabamaAges 1–39 - NCT05442515RecruitingPhase 1/Phase 2
CAR T-cell treatment for hard-to-treat B-cell cancers in youth
This trial tests a personalized immune-cell therapy (CAR T cells) made to attack B-cell cancers that have come back or did not respond to prior treatment. It aims to see how well the treatment works and how safe it is in children and young adults.
Bethesda, MarylandAges 3–39 - NCT05237986Recruiting
Study brain and thinking effects after CAR T therapy in youth
This study looks at how CAR T-cell treatment affects thinking, learning, and day-to-day brain function in children and young adults with certain blood cancers. You (and a caregiver) may complete online testing so researchers can track these changes over time and whether support is needed.
Los Angeles, CaliforniaAges 5 years+ - NCT05057702Recruiting
Personalized surgery-focused treatment plan for relapsed brain cancer
This study tests a personalized treatment plan for children and young adults whose medulloblastoma or ependymoma has come back. It aims to guide doctors using new tissue from surgery or biopsy after earlier treatments are fully finished.
Los Angeles, CaliforniaAges 1–39 - NCT05004116RecruitingPhase 1/Phase 2
Repotrectinib plus chemotherapy for relapsed solid tumors in youth
This early-phase study tests repotrectinib (a targeted anti-cancer pill) combined with chemotherapy in children and young adults whose solid tumors have come back or did not respond to standard treatment. The goal is to see how safe the treatment is and whether it can shrink tumors.
New York, New YorkAges 1–25 - NCT04971850Recruiting
Sleep study for children with possible breathing sleep problems
This trial looks at sleep-related breathing problems (“sleep-disordered breathing”) in children and young adults and how they may affect thinking and memory using sleep study testing plus neurocognitive (thinking) assessments. It may help doctors better understand symptoms and identify who could benefit from treatment.
ParisAges 1–20 - NCT04928677RecruitingPhase 1
Codrituzumab for children and young adults with GPC3-positive solid tumors
This Phase 1 study tests codrituzumab, an antibody medicine, in children and young adults whose solid tumor has come back or did not respond to standard treatment. It’s designed to see how the treatment works and how safe it is, especially for tumors that test positive for GPC3.
Los Angeles, CaliforniaAges 1–21 - NCT04806347RecruitingPhase 1
Stem cell transplant using a half-matched donor for children and young adults
This trial studies a type of stem cell transplant (bone marrow transplant) that uses a donor who is only half-matched to the patient, often a parent or sibling. It is for children and young adults with certain blood diseases, including sickle cell disease, thalassemia, bone marrow failure, and immune disorders. The transplant aims to replace the diseased blood-forming cells with healthy ones from the donor.
Madison, WisconsinAges 3 months–25 years - NCT04836390Enrolling by invitationPhase 2
Donor immune cell treatment after transplant for high-risk AML
This trial tests an additional immune therapy made from donor natural killer (NK) cells given around the time of a special stem cell transplant for children and young adults with high-risk acute myeloid leukemia (AML). It aims to help prevent the leukemia from coming back or not responding after transplant.
Phoenix, ArizonaAges birth–25 years - NCT04684368RecruitingPhase 2
New treatment for children and young adults with a brain tumor
This trial tests a new treatment approach for a rare brain tumor called NGGCT. It aims to see if a different way of treating the tumor can be effective and safe for children and young adults.
Birmingham, AlabamaAges 3–29 - NCT04644016RecruitingPhase 2
Cord blood transplant for children and young adults with blood cancers
This Phase 2 trial studies using a cord blood transplant after finding it is risky enough that standard treatment may not be sufficient. It may help certain children and young adults with specific leukemia, lymphoma, and some non-cancer blood/immune or inherited disorders who do not have a well-matched donor available in time.
New York, New YorkAges Up to 21 years - NCT03983369RecruitingPhase 3
Laser treatment to help prevent painful mouth sores from chemo
This trial tests whether low-level laser therapy (using special light on the mouth) can prevent or reduce mouth sores caused by chemotherapy in children and young adults. It may help you avoid painful inflammation that can affect eating, comfort, and treatment.
Villejuif, Val de MarneAges 4–25 - NCT02390752RecruitingPhase 1
Early drug study for children and young adults with hard-to-treat cancers
This Phase 1 trial tests pexidartinib (TURALIO) to see how safe it is and how well it works against refractory (hard-to-treat) leukemias and solid tumors, including tumors seen with NF1 and MPNST. It mainly helps researchers learn the best way to dose the medication and gather early signals of benefit.
Bethesda, MarylandAges 3–35 - NCT06692868Recruiting
Fertility protection for young cancer patients
This trial offers fertility preservation options for children, teens, and young adults diagnosed with cancer or undergoing stem cell transplant before age 21, to help protect their ability to have biological children in the future.
Ulm, Baden-WurttembergAges Any age - NCT04923126RecruitingPhase 1/Phase 2
Mirdametinib for children with low-grade brain tumors
This Phase 1/2 study tests mirdametinib, a targeted medicine, in children and young adults with low-grade glioma (a slower-growing brain tumor). It aims to find the best dose and see how well the treatment works, especially for tumors with certain “MAPK pathway” changes.
Memphis, TennesseeAges 2–24 - NCT05648019RecruitingPhase 2
CD19 CAR T-cell therapy for tough B-cell blood cancers
This Phase 2 study tests a one-time CAR T-cell treatment aimed at CD19, a target found on many B-cell leukemias and lymphomas. It’s for people whose disease has come back or hasn’t responded to prior treatments, or who can’t have a stem cell transplant.
SingaporeAges birth–70 years - NCT06177600Recruiting
TransHealthGUIDE: Health help for gender-diverse young adults
This study aims to improve healthcare for gender-diverse young adults (ages 18-29) and their caregivers. It involves a program to support transgender and nonbinary health and will take place online.
Boston, MassachusettsAges 18–29 - NCT05043571RecruitingPhase 1
CAR T-cell therapy for relapsed T-cell leukemia
This early-phase trial tests a lab-made immune cell treatment (CAR T-cells) aimed at T-cell leukemia that has come back or did not respond. It may help by targeting leukemia cells with a specific marker (CD7), especially in patients who failed standard treatment.
SingaporeAges 6 months–65 years - NCT04621201Recruiting
Testing tumor genetics in young people with bone sarcomas
This study looks at the genetic (DNA) features of tumors in children, teens, and young adults with osteosarcoma, Ewing sarcoma, or synovial sarcoma. It may help researchers better understand these cancers by analyzing a fresh tumor sample and a blood sample.
Torino, TurinAges Up to 24 years - NCT06087341RecruitingPhase 1
CAR T-Cell Therapy for Advanced Sarcoma in Young People
This trial tests a special type of immune cell (called a CAR T-cell) that is trained to attack sarcoma cells. It is for children, teens, and young adults up to age 40 whose sarcoma has not responded to standard therapy. The treatment is given directly into the tumor, and the goal is to see if it is safe and how well it works.
MadridAges Up to 30 years - NCT05310591RecruitingPhase 1/Phase 2
Study anti-PD1 treatment with Kymriah re-dosing for leukemia
This Phase 1/2 trial studies giving an anti-PD1 antibody (like pembrolizumab or nivolumab) along with a second Kymriah (tisagenlecleucel) infusion in children and young adults whose B-cell leukemia is coming back or their Kymriah effect has faded. It may help the new immune treatment work better after the first Kymriah.
BordeauxAges 1–25
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Common questions
- Are there clinical trials for children, adult?
- Yes. Clin2 currently lists 180 recruiting children, adult studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a children, adult trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a children, adult trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.