Clinical trials
Children, Adult clinical trials
Below are recruiting children, adult clinical trials, each written for real people, not researchers. We’re tracking 184 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06865664RecruitingPhase 1
Engineered immune cells for relapsed rhabdomyosarcoma in youth
This early-phase trial tests a new immune cell therapy (CAR T cells) for children and young adults whose rhabdomyosarcoma has returned or not responded to standard treatments. The goal is to see if these specially engineered cells can find and attack the cancer.
Bethesda, MarylandAges 3–39 - NCT06995872RecruitingPhase 1
Study of rhIL-15 with immunotherapy and chemo for neuroblastoma
This trial tests a new combination of drugs (rhIL-15, dinutuximab, irinotecan, and temozolomide) for children and young adults whose neuroblastoma has come back or hasn't responded to other treatments. The goal is to see if this mix can help shrink or control the cancer.
Bethesda, MarylandAges 3–35 - NCT07000916Recruiting
Follow-up study for new arthritis in kids and young adults
This study follows children and young adults newly diagnosed with certain types of arthritis or related conditions to learn more about their health over time. It may help doctors better understand how these diseases progress and how treatments work.
BrusselsAges 2–50 - NCT07087002RecruitingPhase 1
GPC2-CAR T cells for children and young adults with relapsed medulloblastoma
This trial tests a new type of cell therapy called GPC2-CAR T cells for children and young adults whose medulloblastoma or related brain tumor has come back or not responded to standard treatment. The goal is to see if these specially designed immune cells can find and attack the tumor.
Palo Alto, CaliforniaAges 1–30 - NCT07192952RecruitingPhase 3
Long-term safety of finerenone in children and young adults with heart failure
This study tests the long-term safety of the drug finerenone when taken alongside standard heart failure treatments in children and young adults with weakened heart pumping function (left ventricular systolic dysfunction). It includes both children already in a related study and new infants under 6 months old.
Aurora, ColoradoAges Up to 18 years - NCT07220772RecruitingPhase 3
A drug for severe obesity caused by leptin gene mutations
This trial tests a new drug called mibavademab for people with severe obesity caused by changes in the leptin (LEP) gene. It aims to see if the drug can help with weight loss in children, teens, and adults who have this rare genetic condition.
UlmAges 2 years+ - NCT07223021RecruitingPhase 3
Fludarabine dosing study for B-cell ALL
This study tests a different dose of the chemotherapy drug fludarabine before CAR T-cell therapy (tisagenlecleucel) for children and young adults with B-cell acute lymphoblastic leukemia. The goal is to see if the new dose works better at helping the body accept the CAR T cells while keeping side effects manageable.
New York, New YorkAges 1 year+ - NCT07328503RecruitingPhase 2
CD22 CAR T-cells to prevent relapse after CD19 CAR T-cell therapy
This trial tests if giving a second type of CAR T-cell therapy that targets CD22 can help keep B-cell acute lymphoblastic leukemia (ALL) in remission for people who are already in remission after CD19 CAR T-cell treatment. It aims to reduce the risk of the cancer coming back.
Bethesda, MarylandAges 3–65 - NCT07369024RecruitingPhase 2
Study of low-dose ketamine for sickle cell pain crisis
This study tests whether a low-dose of ketamine (a pain medicine) can help children and young adults with sickle cell disease who are in a pain crisis. It aims to provide better pain relief while avoiding some side effects of standard painkillers.
Torrance, CaliforniaAges 5–20 - NCT02390752RecruitingPhase 1
Early drug study for children and young adults with hard-to-treat cancers
This Phase 1 trial tests pexidartinib (TURALIO) to see how safe it is and how well it works against refractory (hard-to-treat) leukemias and solid tumors, including tumors seen with NF1 and MPNST. It mainly helps researchers learn the best way to dose the medication and gather early signals of benefit.
Bethesda, MarylandAges 3–35 - NCT07483606Recruiting
Turkish study on a tool to prevent toxic chemicals for kids
This trial tests a Turkish version of a tool that helps parents and future parents prevent toxic chemical exposure in children. The study aims to see if the tool is valid and reliable.
Istanbul, AVCILARAges 18 years+ - NCT06998134Recruiting
Exoskeleton walking training for children and young adults
This trial tests whether a robotic leg exoskeleton can help improve walking in children and young adults with certain conditions (like cerebral palsy, muscular dystrophy, spina bifida, or spinal cord injury) or those with no walking issues. The goal is to find out if the exoskeleton is safe and effective for everyday use, especially in younger people who might lose the ability to walk as they get older.
Bethesda, MarylandAges 5–25 - NCT07499349Recruiting
Optimizing Erwinase dosing for ALL patients
This study aims to find the best dose of Erwinase for children with ALL to reduce side effects like high ammonia levels. It focuses on how the drug is processed by the body.
AarhusAges 1 month–45 years - NCT07566377RecruitingPhase 2
Cord Blood Transplant for Children and Young Adults With Blood Cancer
This study tests whether using cord blood stem cells (collected from umbilical cords after birth) can help treat high-risk blood cancers in children and young adults when a matched donor is not quickly available. Cord blood transplants may help prevent cancer from coming back.
New York, New YorkAges Up to 26 years - NCT07607639Recruiting
Gum Health Markers in Children and Young Adults
This study looks at special proteins in the fluid around your gums to understand how gum disease develops in young people. By studying these markers, researchers hope to better understand and treat gum inflammation.
NiğdeAges 8–24 - NCT07521371Enrolling by invitation
Intranasal Insulin for Autism in Children and Young Adults
This study observes how intranasal insulin (a form of insulin delivered through the nose) affects children and young adults with autism spectrum disorder who are already using or planning to use it as part of their regular care. Researchers will track changes in behavior and social skills over about 6 months.
Spring, TexasAges 4–21 - NCT04836390Enrolling by invitationPhase 2
Donor immune cell treatment after transplant for high-risk AML
This trial tests an additional immune therapy made from donor natural killer (NK) cells given around the time of a special stem cell transplant for children and young adults with high-risk acute myeloid leukemia (AML). It aims to help prevent the leukemia from coming back or not responding after transplant.
Phoenix, ArizonaAges birth–25 years - NCT06692868Recruiting
Fertility protection for young cancer patients
This trial offers fertility preservation options for children, teens, and young adults diagnosed with cancer or undergoing stem cell transplant before age 21, to help protect their ability to have biological children in the future.
Ulm, Baden-WurttembergAges Any age - NCT04923126RecruitingPhase 1/Phase 2
Mirdametinib for children with low-grade brain tumors
This Phase 1/2 study tests mirdametinib, a targeted medicine, in children and young adults with low-grade glioma (a slower-growing brain tumor). It aims to find the best dose and see how well the treatment works, especially for tumors with certain “MAPK pathway” changes.
Memphis, TennesseeAges 2–24 - NCT05648019RecruitingPhase 2
CD19 CAR T-cell therapy for tough B-cell blood cancers
This Phase 2 study tests a one-time CAR T-cell treatment aimed at CD19, a target found on many B-cell leukemias and lymphomas. It’s for people whose disease has come back or hasn’t responded to prior treatments, or who can’t have a stem cell transplant.
SingaporeAges birth–70 years - NCT06177600Recruiting
TransHealthGUIDE: Health help for gender-diverse young adults
This study aims to improve healthcare for gender-diverse young adults (ages 18-29) and their caregivers. It involves a program to support transgender and nonbinary health and will take place online.
Boston, MassachusettsAges 18–29 - NCT07380672Recruiting
Relaxation and hypnosis for anxiety after childhood cancer
This study tests whether hypnosis and relaxation exercises can help lower anxiety in kids, teens, and young adults who finished cancer treatment. If you often feel anxious after your cancer journey, you might be able to join and learn new ways to feel calmer.
CaenAges 7–25 - NCT06087341RecruitingPhase 1
CAR T-Cell Therapy for Advanced Sarcoma in Young People
This trial tests a special type of immune cell (called a CAR T-cell) that is trained to attack sarcoma cells. It is for children, teens, and young adults up to age 40 whose sarcoma has not responded to standard therapy. The treatment is given directly into the tumor, and the goal is to see if it is safe and how well it works.
MadridAges Up to 30 years - NCT06124157RecruitingPhase 2
Targeted therapy plus chemo for children with Ph+ or Ph-like B-ALL
This trial tests if adding a targeted drug (dasatinib or imatinib) to a chemotherapy combination with blinatumomab works better for children and young adults with a specific genetic form of B-cell acute lymphoblastic leukemia. The goal is to see if this approach can improve treatment outcomes for patients with Philadelphia chromosome-positive or ABL-class Ph-like B-ALL.
Birmingham, AlabamaAges 1 year–46 years
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Common questions
- Are there clinical trials for children, adult?
- Yes. Clin2 currently lists 184 recruiting children, adult studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a children, adult trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a children, adult trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.