Clinical trials
Chronic Neuropathic Pain clinical trials
Below are recruiting chronic neuropathic pain clinical trials, each written for real people, not researchers. We’re tracking 120 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06964243Recruiting
Brain stimulation for nerve pain relief
This trial tests if mild magnetic pulses to the brain area controlling movement can safely reduce nerve pain from damaged peripheral nerves.
Créteil, Île-de-France RegionAges 18–80 - NCT06994559Recruiting
Music with ketamine for chronic pain
This study tests if listening to music during ketamine infusions helps reduce chronic pain better than ketamine alone. It is for people already getting ketamine infusions for non-cancer pain.
Montreal, QuebecAges 18 years+ - NCT07033195Recruiting
Virtual reality treatment for chronic back pain
This study tests a virtual reality treatment to help adults with chronic low back pain that is not caused by nerve problems. You would use a VR headset at home and attend some study visits, including an MRI, to see if VR can reduce your pain.
Boulder, ColoradoAges 18–85 - NCT07038434Recruiting
Using artificial intelligence to measure pain in chronic pain patients
This study uses artificial intelligence to better understand and measure pain in people with chronic pain. The goal is to develop smarter ways to assess pain automatically, which could lead to better treatment.
Salerno, ItalyAges 18 years+ - NCT07125027Recruiting
A mind-body program for leg pain from back issues
This trial tests a program called Move-MORE that combines movement and mindfulness to help people with long-lasting leg pain caused by a nerve problem in the lower back. It involves daily activities, weekly virtual group meetings, and tracking your progress with a wearable device.
Portland, OregonAges 18–66 - NCT07154056Recruiting
Spinal cord stimulation for stubborn nerve pain
This trial tests a new type of spinal cord stimulation for people with long-term nerve pain that hasn't improved with other treatments. The goal is to see if this special stimulation pattern can reduce pain better than standard care.
Poitiers, FranceAges 18–80 - NCT07153211Recruiting
Chemicals in spinal fluid and blood during spinal cord stimulation for nerve pain
This study is testing a spinal cord stimulation treatment for long-term nerve pain. It will look at certain chemicals in your spinal fluid and blood to understand how the treatment works.
BydgoszczAges 18–80 - NCT07165353Recruiting
Virtual walking to reduce nerve pain after spinal cord injury
This study tests if using a virtual reality walking program can help reduce chronic nerve pain in people with spinal cord injuries. If you have nerve pain in your trunk or legs, you might benefit from this non-drug approach.
Nottwil, Canton of LucerneAges 18–75 - NCT07187219Recruiting
TMS for nerve pain in cancer patients
This trial tests if repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation, can reduce chronic nerve pain caused by cancer or its treatment. It may help patients who have not found relief from standard pain medications.
Saint-EtienneAges 18–85 - NCT07211256Recruiting
Home brain stimulation for chronic pain
This trial tests if a gentle, home-use electrical brain stimulation device (tDCS) can help people with long-lasting pain that hasn't responded well to other treatments. If you have had pain for at least 6 months and a previous brain stimulation helped only briefly, this study may offer a new option.
Boulogne-Billancourt, Hauts de SeineAges 18–80 - NCT07650526Recruiting
Brain Stimulation for Nerve Pain Relief
This study tests two types of magnetic brain stimulation (aiTBS and rTMS) to treat long-lasting nerve pain. Researchers want to see which approach works better and develop a way to predict who will benefit most.
Boulogne-Billancourt, Île-de-France RegionAges 18–80 - NCT07285018RecruitingPhase 2
Study of a new drug for diabetic nerve pain in legs
This trial tests an investigational drug for people with pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It may help reduce pain in your lower legs if other treatments haven't worked well.
Birmingham, AlabamaAges 18 years+ - NCT07301632RecruitingPhase 2
MDMA for severe chronic nerve pain
This trial tests if MDMA, combined with psychotherapy, can help people with severe chronic nerve pain that hasn't improved with standard treatments. You'll receive either MDMA or a placebo to see if it safely reduces pain and improves your quality of life.
Toronto, OntarioAges 18 years+ - NCT07342777Recruiting
Exercise for Pain Relief in Multiple Sclerosis
This study tests whether exercise can help reduce pain in people with multiple sclerosis. If you have MS and moderate to severe pain, you may be asked to participate in a supervised exercise program.
Aarhus, DenmarkAges 18 years+ - NCT07403331Recruiting
Nerve pain in legs: spinal cord stimulation plus team care
This trial tests a treatment bundle that combines a spinal cord stimulator (a device that sends mild electrical pulses to your spine to block pain signals) with a team of specialists (like a psychologist and physical therapist) to reduce chronic nerve pain in the legs and improve your ability to move and function.
OsloAges 18–60 - NCT07436806Recruiting
Comparing nerve blocks for pain after chest surgery
This trial compares two types of nerve blocks to see which one better prevents long-term pain after video-assisted chest surgery. It may help find a way to reduce chronic pain after your procedure.
Istanbul, BagcilarAges 18–75 - NCT06216717Recruiting
Study of electrode location for brain stimulation in chronic pain
This study looks at where electrodes are placed in the brain for people who have a device that stimulates the motor cortex to treat chronic nerve pain. The goal is to help improve how these devices are positioned for better pain relief.
Nice, Alpes MaritimesAges 18 years+ - NCT07250828Enrolling by invitation
BurstDR spinal cord stimulation for painful diabetic neuropathy
This trial tests a type of spinal cord stimulation called BurstDR to see if it can reduce pain from diabetic nerve damage. It may help people with diabetes who have ongoing leg pain that hasn't gotten better with standard pain medications.
Grand Island, NebraskaAges 19 years+ - NCT07046143Enrolling by invitation
Spinal cord stimulation for nerve pain in the lower back
This trial tests a non-invasive treatment that uses mild electrical stimulation on the skin over the spine to help relieve nerve-related pain in the lower back. It may be an option for people with chronic nerve pain, with or without pain spreading down the leg.
Nanchang, JiangxiAges 18–80 - NCT04673981Recruiting
Follow-up study for oral and throat cancer pain
This study looks at nerve-related symptoms and pain in the mouth and throat in people who have been treated for oral or oropharynx cancer. You may be able to take part if you’re within 1 to 5 years after treatment and can follow study steps.
Clermont-FerrandAges 18 years+ - NCT05483816Recruiting
Sensory stimulation trial for nerve pain in people with neuropathy
This study tests a multi-sensory (multiple-sense) stimulation approach to see if it can help people with nerve-related pain in the legs/feet. You must be able to safely take part in MRI-related sessions and answer questions about pain and health history.
Zurich, Canton of ZurichAges 18–80 - NCT05505188Recruiting
Predicting long-term pain after head and neck radiotherapy
This study looks for ways to predict and improve pain you may have months after radiotherapy for first head and neck cancer. It may help doctors better anticipate pain and support patients during recovery.
CaenAges 18 years+ - NCT05700279Recruiting
PTSD treatment to help prevent future chronic pain
This study tests whether treating post-traumatic stress disorder (PTSD) right when you come to the emergency room for new, acute pain can lower the chance you develop long-term (chronic) pain. It may help people whose pain and trauma symptoms start around the same time.
Chicago, IllinoisAges 18–70 - NCT06092749Recruiting
A new treatment for chronic leg and back pain
This trial tests a procedure for people with long-standing leg and back pain that hasn't improved with standard treatments like physical therapy or pain medicine.
CairoAges 21 years+
Hear when a new Chronic Neuropathic Pain trial opens
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Common questions
- Are there clinical trials for chronic neuropathic pain?
- Yes. Clin2 currently lists 120 recruiting chronic neuropathic pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic neuropathic pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic neuropathic pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.