Clinical trials
Chronic Postoperative Pain clinical trials
Below are recruiting chronic postoperative pain clinical trials, each written for real people, not researchers. We’re tracking 298 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06569953RecruitingPhase 4
Numbing Medicine for Pain After Lung Surgery
This study tests whether a long-lasting numbing medicine (liposomal bupivacaine) injected near the spine can better control pain after lung surgery. It compares this to a standard numbing medicine, and aims to help patients recover with less pain after surgery.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT06585033Recruiting
Spinal cord stimulation for pain after back surgery
This trial tests how much of the pain relief from spinal cord stimulation is due to the placebo effect. It is for people with ongoing leg pain after back surgery who have already tried other treatments without success.
ArnhemAges 18–70 - NCT06609772Recruiting
Pain education for liver donors after surgery
This trial tests an individualised pain education program to see if it can reduce chronic pain and improve quality of life for living liver donors after their surgery.
Malatya, BattalgaziAges Any age - NCT06661642Recruiting
Predicting pain after planned surgery
This study looks at whether we can predict how much pain you will feel after surgery. It aims to help doctors better manage pain after your operation.
AalborgAges 18 years+ - NCT06778460Recruiting
Esketamine and lidocaine for pain after liver surgery
This trial tests whether two medicines, esketamine and lidocaine, can reduce long-term pain after liver surgery and possibly improve survival. It is for people who are having a planned liver removal (hepatectomy).
Chengdu, SichuanAges 18–75 - NCT06907810Recruiting
Study of fat molecules in long-term breast surgery pain
This trial looks at how certain natural fat molecules in your body might relate to long-term pain after breast cancer surgery. It could help doctors better understand and treat chronic pain in the future.
Brussels, Brussels CapitalAges 18 years+ - NCT06936995Recruiting
Comparing pain relief methods for ACL surgery recovery
This trial tests two ways to manage pain after ACL reconstruction: a combination of medications (multimodal analgesia) versus a nerve block in the thigh (femoral block). The goal is to see which approach provides better pain control and recovery.
AnkaraAges 18–65 - NCT07073846RecruitingPhase 4
Lidocaine and dexmedetomidine for pain after weight-loss surgery
This study tests whether adding two medicines (lidocaine and dexmedetomidine) to your anesthesia during weight-loss surgery can reduce pain, swelling, and stress on the body. It might help you have a smoother recovery.
Mexico City, Mexico CityAges 18–60 - NCT07198412Recruiting
Study on sedation's effect on back pain after spinal anesthesia
This study looks at whether giving sedation (medicine to help you relax) during spinal anesthesia can reduce back pain after surgery. It's for people having certain types of surgery on their lower abdomen or legs.
Banhā, Qalyubia GovernorateAges 18–65 - NCT07680998Recruiting
Pain monitor device for recovery after day surgery
This trial tests a device that monitors pain and recovery after outpatient surgery. It may help manage pain more safely and improve your comfort after you go home.
Nîmes, GardAges 18 years+ - NCT07257744Recruiting
Pain management after open heart surgery: comparing three methods
This trial compares three ways to manage pain after open heart surgery to see which best prevents long-term chronic pain. It may help you decide with your doctor which pain control option is right for you.
Trabzon, TrabzonAges 18–85 - NCT07308730Recruiting
Pain diary after gallbladder surgery
This study looks at whether using a pain diary can help people manage pain better after gallbladder removal surgery. If you are having this surgery for the first time and can read and write in Turkish, you may be able to join.
Muğla, MenteşeAges 18 years+ - NCT07336264Recruiting
Understanding acute pain in children
This study looks at how children and teens experience pain after surgery or during a bone marrow transplant. It aims to better understand acute pain, which is short-term pain that goes away as the body heals.
Washington D.C., District of ColumbiaAges 6–21 - NCT07436806Recruiting
Comparing nerve blocks for pain after chest surgery
This trial compares two types of nerve blocks to see which one better prevents long-term pain after video-assisted chest surgery. It may help find a way to reduce chronic pain after your procedure.
Istanbul, BagcilarAges 18–75 - NCT07633444Recruiting
Ear Stimulation to Reduce Pain After Abdominal Surgery
This study tests whether mild electrical stimulation applied to your ear can reduce pain and the need for pain medication after abdominal or urologic surgery. Researchers will try different stimulation frequencies to find what works best.
Salvador, Estado de BahiaAges 18–59 - NCT07640646Recruiting
Heart Surgery and Long-Term Pain: A Patient Survey
This study asks patients who had heart surgery in the past year about any ongoing pain or discomfort in the surgical area. The goal is to understand how common long-term pain is after heart surgery and how it affects daily life.
Leuven, Vlaams BrabantAges 18 years+ - NCT07662733Recruiting
Acupuncture for better sleep and less pain after lung cancer surgery
This trial tests if acupuncture given before and after surgery can help patients sleep better and have less chronic pain after a lung cancer operation. You may join if you are having a specific type of lung cancer surgery, are in good general health, and do not have severe sleep problems already.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07242872Enrolling by invitation
Screen addiction and pain after nose surgery
This trial looks at whether screen addiction affects pain levels after rhinoplasty (nose job). It will help doctors understand if screen habits influence recovery.
Tokat Province, Tokat ProvinceAges 18–45 - NCT07123402Enrolling by invitationPhase 2
TRD205 for chronic pain after surgery
This trial tests a new tablet called TRD205 for people who have had long-lasting nerve pain after surgery (at least 3 months). The goal is to see if it can reduce pain safely.
BeijingAges 18–80 - NCT07706348RecruitingPhase 1/Phase 2
Pain relief with ondansetron and lidocaine after abdominal cancer surgery
This trial tests if rinsing the belly with ondansetron (a nausea medicine) and lidocaine (a numbing medicine) during surgery can reduce pain afterward. It is for people having major lower abdominal cancer surgery who are otherwise healthy.
AsyutAges 20–70 - NCT06244732Recruiting
Pain control after open aneurysm surgery
This study tests two different ways to manage pain after open surgery for an abdominal aortic aneurysm. It compares a standard pain control method to another approach that may reduce the need for strong painkillers.
San Donato Milanese, MilanAges 18 years+ - NCT06704490Recruiting
Chronic pain after planned cesarean section
This study looks at how common chronic pain is after a planned cesarean section and what factors might increase that risk. It could help doctors better prevent and manage long-term pain after delivery.
Wuhan, HubeiAges 20–50 - NCT06784089Recruiting
Hip fracture type, nutrition and pain after surgery
This study looks at how a person's nutrition before hip surgery relates to their pain levels after surgery. It aims to help doctors improve recovery for older adults.
AnkaraAges 65 years+ - NCT07448246Recruiting
Rhomboid block for pain after breast implant surgery
This trial tests if a specific nerve block (rhomboid intercostal block) can reduce pain after breast implant surgery. If you are having bilateral breast implants and are in good general health, you may be eligible.
Aydin, EfelerAges 18–65
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Common questions
- Are there clinical trials for chronic postoperative pain?
- Yes. Clin2 currently lists 298 recruiting chronic postoperative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic postoperative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic postoperative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Postoperative Pain
- Postoperative Pain, Acute
- Postoperative Pain Management
- Total Knee Arthroplasty (Postoperative Pain)
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
- Postoperative Pain After Endodontic Treatment
- Postoperative Pain Following Knee Arthroplasty
- Postoperative Pain Management in Oral Surgery
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.