Clinical trials
Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer) clinical trials
Below are recruiting chronic wound of the lower limb (leg ulcer or foot ulcer) clinical trials, each written for real people, not researchers. We’re tracking 173 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05287646Recruiting
Track how your residual limb moves while walking with a prosthesis
This study uses a special X-ray and markers to measure how your leg and skin move inside your prosthetic socket while you walk. It may help researchers better understand fit and comfort for people with transtibial (below-knee) amputations.
New York, New YorkAges 18 years+ - NCT07760363Recruiting
Foot exercise device for leg swelling
This study tests if using a foot pedal device while lying down can help reduce leg swelling in the hospital. It aims to see if this simple exercise can improve comfort and outcomes for people with fluid buildup.
Tulsa, OklahomaAges 18 years+ - NCT07696728Recruiting
Pulsed magnetic field therapy for diabetic foot ulcer sensation
This trial tests whether a painless pulsed electromagnetic field treatment can improve feeling in diabetic foot ulcers. It is designed for people with type 2 diabetes who have had a foot ulcer for a while and have lost some sensation due to nerve damage.
Faisalabad, Punjab ProvinceAges 40–60 - NCT06693180Recruiting
Hyperbaric oxygen therapy for diabetic foot ulcers
This trial is testing whether hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) can help heal diabetic foot ulcers. It is for people with diabetes who have a foot ulcer that is not healing well.
Amsterdam, North HollandAges 18 years+ - NCT07620379Recruiting
Pressure-Relief Materials for Diabetic Foot Ulcers
This study tests special cushioning materials designed to reduce pressure and help heal diabetic foot ulcers. Researchers want to find the best way to distribute pressure on the foot to support healing and prevent future ulcers.
Valencia, ValenciaAges 55–75 - NCT06141811Recruiting
Long-term safety study for diabetic foot ulcer treatment
This study follows up on patients who received an experimental cell sheet (ALLO-ASC-DFU) or a placebo in a previous trial. It checks for any new safety concerns over time.
Bucheon-si, Gyeonggi-doAges 19–75 - NCT07565506RecruitingPhase 2
Nu-3 Gel for Mild Diabetic Foot Infections
This study tests a new gel treatment (Nu-3) for mild infections in diabetic foot ulcers. The goal is to find the right dose and see if it helps heal these wounds safely.
Los Angeles, CaliforniaAges 18 years+ - NCT07512960RecruitingPhase 3
Blood Thinner Duration After Leg Artery Treatment
This trial tests how long patients should take two blood-thinning medications (aspirin and clopidogrel) after treatment to restore blood flow to a severely damaged leg. The goal is to find the right balance between preventing clots and avoiding dangerous bleeding.
Paris, Île-de-France RegionAges 18–99 - NCT07391319RecruitingPhase 3
Testing a new treatment for diabetic foot ulcers
This trial tests a new treatment for foot ulcers caused by poor blood flow and diabetes. It compares the new treatment to a placebo (an inactive substance) to see if it helps ulcers heal better.
MoscowAges 18 years+ - NCT07397390Enrolling by invitation
Study of a new scoring balloon for leg artery blockages with heavy calcium buildup
This study tests a new balloon device that scores the artery walls to treat leg artery blockages with heavy calcium deposits. It aims to see if the device helps prepare the vessel safely and effectively before placing a stent.
Dalian, LiaoningAges 18–85 - NCT07307183Recruiting
Predicting foot ulcers risk in diabetes
This study is developing a tool to predict your risk of getting foot ulcers if you have diabetes. By analyzing medical records, the researchers hope to identify people who need extra prevention and care.
JonseredAges 18 years+ - NCT07300163Recruiting
FeetSee: Thermal images for diabetes foot health
This study collects thermal (heat) images of the feet of people with diabetes who have had a healed foot ulcer. The goal is to see if these images can help prevent future foot problems.
VilniusAges 18 years+ - NCT07131410Enrolling by invitation
Hyaluronic acid cream to prevent foot ulcers in diabetes
This trial tests a cream made with hyaluronic acid, a natural substance that helps keep skin moist, to see if it can prevent foot sores in people with type 2 diabetes and nerve damage in their feet. If you have diabetes-related nerve issues and want to protect your feet, this study may be for you.
MálagaAges 18 years+ - NCT06886633Enrolling by invitation
Breathing exercise and cold pack for wound cleaning pain
This study tests whether a simple breathing exercise and a cold pack can help reduce pain and anxiety while a wound is being cleaned (called sharp debridement). If you are having a wound cleaned and feel anxious about it, this may be a way to feel more comfortable.
Gaziantep, GaziantepAges Any age - NCT06483620Recruiting
Arabic quality of life questionnaire for diabetic neuropathy
This trial tests a new Arabic questionnaire to measure quality of life for people with diabetic neuropathy. It helps doctors understand how nerve pain affects daily life.
Cairo, Giza GovernorateAges 18–70 - NCT06311773Enrolling by invitation
Testing the Boomerang Catheter for severe leg artery disease
This trial tests a new device called the Boomerang Catheter for people with severe leg artery disease (CLTI) who have no other treatment options to save their limb. The goal is to see if this catheter can restore enough blood flow to help the leg heal.
San Bernardino, CaliforniaAges 18 years+ - NCT06071429Recruiting
Dissolvable medicine stent for leg artery disease
This trial tests a new dissolvable stent that slowly releases medicine to keep your lower-leg artery open. It is for people with severe leg pain or small wounds due to poor blood flow, and who are not eligible for other stents.
New York, New YorkAges 18 years+ - NCT04460573RecruitingPhase 2
Using a smart boot to improve diabetic foot offloading
This trial studies whether a special “smart boot” can help people with diabetic foot ulcers rest (offload) the affected foot as they should. Better offloading may improve healing by reducing pressure on the wound.
Downey, CaliforniaAges 18 years+ - NCT04979078Recruiting
Light therapy to ease chemotherapy hand-foot skin reaction
This study tests whether a light-based therapy (photobiomodulation) can reduce pain and skin irritation from hand-foot syndrome/hand-foot skin reaction in people getting chemotherapy or targeted medicines. It may help you heal sooner and feel more comfortable while treatment continues.
Hasselt, LimburgAges 18 years+ - NCT07379684RecruitingPhase 1
Amicidin-β for infected surgical or traumatic wounds
This trial tests a topical solution called Amicidin-β for people with infected surgical or traumatic wounds. It may help treat the infection without needing strong oral or IV antibiotics.
Torrance, CaliforniaAges 18–79 - NCT07114445Enrolling by invitation
Virtual reality foot care training for type 2 diabetes
This trial tests if using virtual reality glasses to teach foot care can help people with type 2 diabetes take better care of their feet. It aims to prevent serious foot problems.
Gaziantep, GaziantepAges 18 years+ - NCT06973850Enrolling by invitation
Online Foot Care Education for Older Adults with Diabetes
This study tests a nurse-led online education program designed to help older adults with diabetes feel more confident about taking care of their feet and understand the risks of foot problems. You would learn through videos or virtual meetings from home.
Al Mansurah, MansouraAges 60 years+ - NCT06964802Recruiting
Cold salt water foot bath to prevent nerve damage from chemo
This trial tests whether soaking your feet in cold salt water before chemotherapy can help prevent nerve damage (called peripheral neuropathy) that is a common side effect of the breast cancer drug paclitaxel.
Istanbul, UskudarAges 18 years+ - NCT06655116Enrolling by invitation
Diabetes foot education study
This trial tests a structured education program for people with type 2 diabetes to help prevent foot problems. It's for those who haven't had formal foot training before.
Kayseri, TalasAges 18 years+
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Common questions
- Are there clinical trials for chronic wound of the lower limb (leg ulcer or foot ulcer)?
- Yes. Clin2 currently lists 173 recruiting chronic wound of the lower limb (leg ulcer or foot ulcer) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic wound of the lower limb (leg ulcer or foot ulcer) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic wound of the lower limb (leg ulcer or foot ulcer) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.