Clinical trials
Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer) clinical trials
Below are recruiting chronic wound of the lower limb (leg ulcer or foot ulcer) clinical trials, each written for real people, not researchers. We’re tracking 173 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04312451Recruiting
Study of severe leg blood-flow problems after a procedure
This study follows adults with very poor blood flow to the foot or leg (with wounds or severe pain) who are having a revascularization procedure to improve circulation. It may help doctors understand outcomes after treatment and improve care for people with critical limb ischemia.
ParisAges 18 years+ - NCT06353568Recruiting
Light therapy to prevent diabetic foot ulcers
This study tests a painless light treatment (photobiomodulation) to see if it can prevent foot ulcers in people with type 2 diabetes who are at risk. If you qualify, you would receive the treatment regularly and be monitored for foot health.
São Paulo, São PauloAges 18–75 - NCT07562230Recruiting
Tissue-engineered skin to repair difficult wounds
This trial tests a lab-grown skin product designed to help heal stubborn wounds that won't close on their own—including burns, diabetic foot ulcers, and pressure sores. The goal is to see if this engineered skin can speed up healing and reduce scarring.
Guangzhou, GuangdongAges Any age - NCT07493642Recruiting
Video health program for chronic kidney disease patients
This trial tests whether watching educational videos about exercise and staying active can improve physical fitness for people with early to moderate chronic kidney disease. You can take part from home using a smartphone, tablet, or computer.
New Taipei City, Taishan DistrictAges 20 years+ - NCT06271382Recruiting
Acupressure and foot exercises for type 2 diabetes
This study tests whether acupressure (a gentle pressure technique) and simple foot exercises can improve blood flow in the feet of people with type 2 diabetes. It may help prevent circulation problems.
BoluAges 18 years+ - NCT07260656RecruitingEarly Phase 1
Capsaicin cream for diabetic nerve foot pain
This trial tests a new cream (Capsadyn®) made from chili pepper extract to see if it can reduce nerve pain in the feet caused by diabetes. If it works, it could offer a simple treatment you apply at home.
Roanoke, VirginiaAges 25–75 - NCT07248631Recruiting
Exercises and mindful walking for diabetic nerve pain
This study tests whether combining foot and ankle exercises with mindful walking can reduce pain and improve mobility in people with diabetic nerve damage in their feet.
Multan, Punjab ProvinceAges 3.3 years–6.3 years - NCT07040488Recruiting
Infrared camera study for diabetic foot in Guadeloupe
This study uses a special infrared camera to measure heat patterns in the feet of people with diabetes in Guadeloupe. The goal is to see if this painless method can help detect or monitor foot problems, which may prevent ulcers.
Pointe-à-PitreAges 18 years+ - NCT07016438Recruiting
Study of PAL-222 for stubborn skin ulcers
This trial tests a new treatment, PAL-222, for skin ulcers that haven't improved much after 4 weeks of standard care. It aims to see if PAL-222 can help these wounds heal better.
Kyoto, Shogoin-kawahara-cho, Sakyo-ku, KyotoAges 20 years+ - NCT06780202RecruitingPhase 2
Steroid to reduce opioid use after foot/ankle surgery
This study tests whether a steroid medicine called Medrol Dosepak can help reduce the need for opioid painkillers after foot or ankle surgery. If you are having foot or ankle surgery at Emory and are generally healthy, you may be able to join.
Atlanta, GeorgiaAges 18–95 - NCT06771531Recruiting
Brain stimulation for foot sensation in older adults
This trial tests whether a gentle brain stimulation technique can improve feeling and steadiness in the feet of older adults who have numbness or reduced sensation. It aims to help with balance and walking.
Roslindale, MassachusettsAges 65 years+ - NCT05639478Recruiting
Foot care and exercise program for people with diabetes
This trial tests whether a structured foot-care and exercise program in primary care helps adults with diabetes. It may help you stay more active and reduce foot problems by teaching daily care and safe movement.
Limeira, São PauloAges 18 years+ - NCT02375802Enrolling by invitationPhase 1
Stem cell treatment for pressure sores and some diabetic foot ulcers
This Phase 1 study tests whether injected stem cells can help wounds heal faster or better. It focuses on people with specific wound types and sizes, and checks safety and wound healing over weekly visits.
Jacksonville, FloridaAges 18 years+ - NCT06734832RecruitingPhase 3
Vaccine trial for hand, foot, and mouth disease
This trial tests a new two-in-one vaccine to protect children against hand, foot, and mouth disease caused by two common viruses (EV71 and CA16). It is for healthy kids ages 6 months to 5 years and will check if the vaccine is safe and works well.
Hefei, AnhuiAges 6 months–5.9 years - NCT07507422Recruiting
Post-market study of Inceptiv spinal cord stimulation
This study follows people receiving Inceptiv, a spinal cord stimulator from Medtronic, to see how well it works over time. It is for adults with chronic back or limb pain who have not tried spinal cord stimulation before.
Phoenix, ArizonaAges 18 years+ - NCT03877653Recruiting
Freedom-1 treatment for long-term knee pain in adults
This study tests a procedure called Freedom-1 to reduce long-term, limiting knee pain from knee arthritis. It may help if other non-surgical options didn’t work and you meet specific knee and health requirements.
Placentia, CaliforniaAges 18 years+ - NCT05643079Recruiting
Bone screw and tendon transfer for heel bone realignment
This trial studies a specific surgical technique for people who need heel bone realignment along with a tendon transfer. It tests whether using a human donor bone screw helps the bone heal and the tendon work after surgery.
ViennaAges 18 years+ - NCT07242729Recruiting
Compare two treatments for chronic heel pain from plantar fasciitis
This study compares two treatments—bone marrow aspirate and platelet-rich fibrin—to see which works better for long-lasting heel pain caused by plantar fasciitis. It may help if your pain has not improved with standard treatments like stretching or physical therapy.
São PauloAges 18–75 - NCT06084052Recruiting
Mobile app study to prevent foot ulcers in diabetes
This trial tests a mobile app to help prevent foot ulcers in people with diabetes who are at high risk. You will use the app to track your foot health and get advice to keep your feet safe.
LondonAges 18–100 - NCT07134335RecruitingPhase 2
Study of UBT251 injection for chronic kidney disease
This study tests an investigational injection called UBT251 for people with chronic kidney disease who are overweight. It aims to see if it can reduce protein in the urine and help protect kidney function.
BeijingAges 18–75 - NCT06912646Recruiting
Laser therapy for foot pain from idiopathic neuropathy
This trial tests a laser device for temporary relief of foot pain from peripheral neuropathy when the cause is unknown. It may help if you have constant foot pain and are not diabetic.
Miramar, FloridaAges 22 years+ - NCT04511247Recruiting
Drug-coated balloon for artery disease below the knee
This trial tests a drug-coated balloon to open narrowed or blocked arteries in the lower leg (below the knee) and help them stay open. It’s meant for people with significant symptoms, to reduce re-narrowing after treatment.
SingaporeAges 21 years+ - NCT06828653Recruiting
Comparing 3D-printed vs standard ankle braces for walking
This study compares custom-made ankle-foot braces made with a digital 3D printing method versus the traditional plaster cast method. It aims to find out which type is more comfortable and effective for people with conditions like cerebral palsy, stroke, or spinal cord injury who need a brace to help them walk better.
Mississauga, OntarioAges 8 years+ - NCT06778005Recruiting
Ultrasound of leg nerves in type 2 diabetes with nerve damage
This study uses ultrasound (an imaging test) to measure the nerves in the legs of people with type 2 diabetes who have nerve damage. It helps doctors learn more about how diabetes affects nerves.
Istanbul, ÜsküdarAges 18–65
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Common questions
- Are there clinical trials for chronic wound of the lower limb (leg ulcer or foot ulcer)?
- Yes. Clin2 currently lists 173 recruiting chronic wound of the lower limb (leg ulcer or foot ulcer) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic wound of the lower limb (leg ulcer or foot ulcer) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic wound of the lower limb (leg ulcer or foot ulcer) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.