Clinical trials
Cirrhosis clinical trials
Below are recruiting cirrhosis clinical trials, each written for real people, not researchers. We’re tracking 261 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06464952Recruiting
Prebiotics for PTSD and cirrhosis
This trial tests if a prebiotic supplement can improve gut health and PTSD symptoms in people with cirrhosis and PTSD. It aims to see if changing the gut microbiome can help both conditions.
Richmond, VirginiaAges 18 years+ - NCT06461208RecruitingPhase 3
Fecal transplant for people with cirrhosis
This trial tests whether transplanting healthy gut bacteria (from donor stool) can improve outcomes in people with cirrhosis. If you have mild to moderate cirrhosis, you may be able to join.
BasildonAges 18 years+ - NCT06425380Recruiting
Resistant potato starch for liver cirrhosis and confusion
This study is testing whether a special type of starch (resistant potato starch) can help people with cirrhosis who have had episodes of confusion from liver problems. It may help by changing the bacteria in your gut, which could reduce the risk of future confusion episodes.
Rochester, MinnesotaAges 18–99 - NCT04801290Recruiting
TIPS procedure for people with worsening liver cirrhosis
This trial studies the TIPS procedure in people with decompensated (worsening) liver cirrhosis to see how it helps. You may be considered if you need a TIPS procedure and can receive care at the study hospital.
Hanover, Lower SaxonyAges 18–99 - NCT06419374RecruitingPhase 3
Testing a new drug for liver scarring from MASH
This trial tests a new drug called pegozafermin to see if it can help people with cirrhosis (scarring) of the liver caused by MASH (a fatty liver disease). If you have cirrhosis and either diabetes or multiple risk factors, this study might be an option for you.
Birmingham, AlabamaAges 18–75 - NCT06396897Recruiting
Hospital at Home for Cirrhosis Recovery
This study tests whether recovering from cirrhosis at home, with a nurse visiting daily, works as well as staying in the hospital. You'll be enrolled in the Hospital at Home program and need a caregiver to help for the first two days.
Indianapolis, IndianaAges 18 years+ - NCT06345547Recruiting
Muscle mass ultrasound study in cirrhosis patients
This study uses ultrasound to measure muscle mass in people with cirrhosis. It aims to understand muscle changes and their link to health outcomes.
Edegem, AntwerpenAges 18 years+ - NCT06316869Recruiting
Ultrasound test for high blood pressure in cirrhosis
This study tests a new, painless ultrasound method to check for high blood pressure in the liver's main blood vessel. It aims to avoid more invasive tests for people with cirrhosis. It might help doctors tell if you are at risk of bleeding without a catheter procedure.
Wenzhou, ZhejiangAges 18 years+ - NCT03267615Recruiting
Study in advanced liver scarring using pressure and stiffness tests
This study looks at people over 18 who have advanced, long-term liver scarring. It uses specialized measurements of liver stiffness and pressure to confirm eligibility and may help doctors better understand this condition.
ViennaAges 18–100 - NCT06150482Recruiting
Healthcare use in liver cirrhosis patients
This study looks at how often people with liver cirrhosis use healthcare services. The goal is to understand what types of medical care patients with cirrhosis need over time.
Apeldoorn, GelderlandAges 18 years+ - NCT06265272Recruiting
PSMA-11 PET/MRI for Liver Cirrhosis
This study uses a special PET/MRI scan with a tracer called PSMA-11 to look at how liver cirrhosis affects the liver. It may help doctors better understand and monitor the disease.
Charlestown, MassachusettsAges 18–99 - NCT06223893Recruiting
Smartphone app to improve care after cirrhosis hospitalization
This study tests how well a smartphone app helps people with cirrhosis who have been hospitalized for sudden liver problems. It aims to improve care and access to treatment after you go home.
BirminghamAges 18 years+ - NCT06205992Recruiting
Comparing 2D and 3D MRI scans for liver scarring and pressure
This study compares two types of MRI scans (2D and 3D) to see which is better at measuring liver scarring and high blood pressure in the liver's main vein. It is for people with cirrhosis who are already scheduled to have their liver vein pressure measured.
Shenyang, LiaoningAges 18–75 - NCT06174272Recruiting
Better care after hospital for liver swelling
This trial tests a program to help people with cirrhosis and severe fluid swelling get better care after leaving the hospital. It focuses on guiding you through treatment with water pills and managing fluid buildup at home.
Hershey, PennsylvaniaAges 18 years+ - NCT04613921Recruiting
Liver transplant study for severe worsening liver failure
This study looks at when liver transplant is offered and what outcomes happen in people with cirrhosis who have severe “acute-on-chronic” worsening. It may help doctors decide which patients benefit most from transplant and improve care after listing or not listing.
Los Angeles, CaliforniaAges 18–80 - NCT06007846RecruitingPhase 2/Phase 3
Memantine for advanced liver cancer and cirrhosis
This trial tests if memantine, a medication typically used for memory problems, can help people with advanced liver cancer and cirrhosis. It is for those who cannot have standard aggressive treatments.
Fairfax, VirginiaAges 18 years+ - NCT05982769Recruiting
Exercise for cirrhosis patients
This study tests whether a supervised exercise program can help people with cirrhosis (scarred liver) feel stronger and improve their health. You'll be asked to exercise regularly and have tests to see how your muscles and liver respond.
Cleveland, OhioAges 21–65 - NCT05783661RecruitingPhase 4
Antibiotic plan guided by infection tracking in cirrhosis
This study compares standard antibiotic treatment versus antibiotic choices guided by local infection tracking (epidemiological surveillance) in people with cirrhosis who have an acute worsening and likely a bacterial infection. It may help doctors choose antibiotics more accurately and safely in this high-risk situation.
BarcelonaAges 18 years+ - NCT05726032RecruitingPhase 2
Empagliflozin for fluid buildup from cirrhosis
This Phase 2 study tests empagliflozin to see if it can improve fluid buildup (ascites) in people with cirrhosis. It may help reduce symptoms related to fluid retention, but you must meet specific safety and stability requirements.
New Haven, ConnecticutAges 18 years+ - NCT05475015Recruiting
3D MRI scan to assess liver scarring and pressure
This study tests whether a special 3D MRI scan (3D-MRE) can measure liver scarring and the high pressure in the liver called portal hypertension. It may help your team use imaging to understand how severe your liver disease is, especially when a pressure test (HVPG) is being considered.
Shenyang, LiaoningAges 18–75 - NCT05431946Enrolling by invitation
Palliative care support for people with liver cirrhosis
This trial studies a palliative care approach—comfort-focused support aimed at improving quality of life—for people with liver cirrhosis. It may help by addressing symptoms and planning care together with you and your family.
EsbjergAges 18 years+ - NCT05428267Recruiting
Sexual function study for people with cirrhosis
This study looks at sexual dysfunction in people who have cirrhosis (scarring of the liver). It may help researchers understand causes and better care for sexual problems in this condition.
ParisAges 18 years+ - NCT05205954Recruiting
Home hospital care for adults with advanced liver disease
This pilot study tests whether a “home hospital” program can safely care for people with advanced liver disease after they are admitted to the hospital. It may reduce time in the hospital while still treating serious complications like fluid buildup, breathing fluid, or confusion from liver disease.
Boston, MassachusettsAges 18 years+ - NCT05166499Recruiting
Amino acids to help rebuild muscle in liver cirrhosis
This trial tests whether a special amino-acid supplement can help reverse muscle loss in people with cirrhosis (scarring of the liver). It may help maintain or improve muscle strength and overall function, but eligibility depends on your liver status and overall health.
Cleveland, OhioAges 21–65
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Common questions
- Are there clinical trials for cirrhosis?
- Yes. Clin2 currently lists 261 recruiting cirrhosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cirrhosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cirrhosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.