Clinical trials
Cognitive Disorder clinical trials
Below are recruiting cognitive disorder clinical trials, each written for real people, not researchers. We’re tracking 451 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05377125Recruiting
Training brain skills to reduce urges in OCD spectrum
This study tests a training program meant to improve “response inhibition,” the brain’s ability to pause before acting on unwanted urges. It may help people with OCD-spectrum conditions like obsessive-compulsive disorder, trichotillomania (hair pulling), or skin picking by targeting brain control of impulses.
Milwaukee, WisconsinAges 18–60 - NCT04239079Recruiting
Study of immune-related changes in Parkinson’s and Alzheimer’s
This study looks for “autoimmune-like” (immune-system) features in brain-related diseases such as Parkinson’s and Alzheimer’s, using genetic testing and other assessments. Results may help researchers understand what drives these conditions and who might be more likely to have immune-related changes.
New York, New YorkAges 55–90 - NCT05726045Recruiting
Sleep-based brain training to help you quit smoking
This study tests a way to improve smoking cessation using special sleep-based brain stimulation and memory support. If it works, it may help you stay committed to quitting by strengthening helpful brain learning during sleep.
Mannheim, Baden-WurttembergAges 18–65 - NCT06338397Recruiting
Social and emotional thinking in Alzheimer's
This study looks at how Alzheimer's disease and similar conditions affect social and emotional thinking. Researchers will use brain scans and questionnaires to understand these changes better.
LilleAges 40–85 - NCT07349706Recruiting
Breathing exercise for dementia risk reduction
This trial tests a simple breathing exercise done for about 5–10 minutes each day for 8 weeks. It aims to see if this exercise can reduce your risk of dementia. If you are between 60 and 80 years old and have at least one risk factor for dementia, this study may be a fit for you.
Tallahassee, FloridaAges 60–80 - NCT06532500Recruiting
CBT therapy for teen mood and anxiety
This study tests whether cognitive behavioural therapy (CBT) — a talk therapy that helps you change unhelpful thoughts and behaviors — can improve mood and anxiety in teens. If you're between 14 and 19 and have a mood or anxiety disorder, this therapy might be a good fit.
Toronto, OntarioAges 14–19 - NCT04159662Recruiting
Brain scans to study thinking in schizophrenia and depression
This study uses brain imaging to better understand how thinking works in people with schizophrenia or major depression. Your results may help researchers learn what brain patterns match different thinking and symptoms.
Ottawa, OntarioAges 18–60 - NCT04414215Recruiting
Emotion-focused brain training for schizophrenia or schizoaffective disorder
This study tests a structured cognitive (thinking/skill) training program aimed at improving how people manage emotions. It may help by teaching emotion regulation skills alongside existing care.
Athens, GeorgiaAges 18–60 - NCT05906069Recruiting
Internet CBT program study for OCD patients
This trial studies whether an online version of cognitive behavioral therapy (CBT, a structured talk-therapy approach) helps people with obsessive-compulsive disorder (OCD), and tries to predict who will benefit most. It may help by improving treatment planning and matching therapy to the right person.
Braga, GualtarAges 18–65 - NCT06898177Recruiting
Mobile app for ARFID therapy
This study tests a mobile app that provides cognitive-behavioral therapy for avoidant/restrictive food intake disorder (ARFID). It aims to help people who have trouble eating enough or a limited variety of foods, and can be done from home using a smartphone.
Boston, MassachusettsAges 18–55 - NCT06684444Enrolling by invitationPhase 4
Sleep coaching study for firefighters with sleep troubles
This study tests if health coaching can help career firefighters sleep better. You'll have private coaching sessions by phone or computer.
Tucson, ArizonaAges 18 years+ - NCT07318480Recruiting
tDCS for Cocaine Use Disorder
This study tests whether a non-invasive brain stimulation method called tDCS can help reduce cocaine use. You would receive several sessions of mild electrical current applied to your scalp, which may help control cravings and improve your ability to stay abstinent.
New York, New YorkAges 18–60 - NCT06563310Recruiting
Brain Training for Anxiety Using Neurofeedback
This study tests whether a brain-training technique called neurofeedback can help people with certain anxiety disorders learn to change how they think about upsetting situations. Participants will do thinking exercises while an MRI machine measures their brain activity, which helps them see if they are using the right coping strategies.
Ann Arbor, MichiganAges 18–24 - NCT04390646RecruitingPhase 2/Phase 3
Hormone treatment to study thinking in Down syndrome
This trial studies whether a GnRH hormone treatment can improve thinking and memory in people with Down syndrome. It also checks safety and whether the treatment affects brain-related changes seen on MRI.
Lausanne, Canton of VaudAges 16–50 - NCT06914284Recruiting
Apathy and thinking changes in older adults with bipolar disorder
This study looks at whether apathy and certain brain markers can help predict memory and thinking problems in people over 70 with bipolar disorder. If you are 70-85, have bipolar disorder, and are currently stable (no recent mood episodes), you may be able to join.
Rennes, Ile Et VilaineAges 70–85 - NCT05062369Recruiting
Brain stimulation plus training to support alcohol abstinence
This study tests whether a combination of brain stimulation (tDCS) and cognitive training can help people with alcohol use disorder stay abstinent. You may be included if you are currently not drinking and can commit to the program timeline.
Minneapolis, MinnesotaAges 18–65 - NCT06118268Recruiting
Brain stimulation to improve social thinking in psychosis
This study tests whether a type of brain stimulation called intermittent theta burst stimulation (iTBS) can help improve social thinking and understanding in people with psychosis. Researchers want to see if this treatment can boost how you read social cues and connect with others.
Glen Oaks, New YorkAges 18–39 - NCT02914951Enrolling by invitation
Therapy to reduce irritability in children with autism
This trial studies whether cognitive-behavioral therapy (a structured talk therapy) can reduce irritability and anger outbursts in children with autism. It may help improve day-to-day behavior by teaching coping skills and reducing problem reactions.
New Haven, ConnecticutAges 8–16 - NCT07420478Recruiting
TF-CBT for autistic youth with trauma
This trial tests trauma-focused therapy for autistic youth who have experienced trauma. It aims to see if this therapy helps reduce trauma-related distress.
Lebanon, New HampshireAges 6 years+ - NCT05608434RecruitingPhase 1/Phase 2
VR training for improving attention in kids with ADHD
This study tests a virtual reality (VR) program meant to strengthen attention skills in children with ADHD. It compares different VR-based training options and looks at whether kids improve on attention-related thinking skills after the sessions.
Bethesda, MarylandAges 8–16 - NCT03948893Recruiting
Behavior program to help you quit nicotine
This study tests a structured counseling/behavior treatment to help people who smoke become nicotine-free. If you’re interested in quitting, you may be asked to complete questionnaires and follow a quit plan as part of the research.
Columbia, MissouriAges 18 years+ - NCT04007380Recruiting
Sleep problems after spinal cord injury study
This study looks at how sleep-disordered breathing (breathing problems during sleep) affects mood, thinking, and behavior after a spinal cord injury. It may help researchers understand the impact of these sleep breathing issues and guide better support for people after injury.
Toronto, OntarioAges 18 years+ - NCT05598034Recruiting
Brain stimulation with tDCS for moderate depression
This study tests whether a noninvasive brain stimulation called tDCS can improve depression symptoms. It also uses MRI scans, aiming to understand how brain changes may relate to symptom improvement.
Los Angeles, CaliforniaAges 20–55 - NCT05783817RecruitingPhase 2
MDMA-assisted therapy for OCD in adults
This trial tests whether MDMA plus cognitive behavioral therapy (CBT) can reduce OCD symptoms in adults who have tried standard OCD treatments before. You may be asked to pause certain medicines and follow specific diet/medication rules around the study session.
Palo Alto, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for cognitive disorder?
- Yes. Clin2 currently lists 451 recruiting cognitive disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.