Clinical trials
Colorectal (Colon or Rectal) Cancer clinical trials
Below are recruiting colorectal (colon or rectal) cancer clinical trials, each written for real people, not researchers. We’re tracking 893 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05998187RecruitingPhase 3
Botox injections for fecal incontinence
This trial tests whether botulinum toxin (Botox) injections into the rectum can improve bowel control in people with active fecal incontinence. It aims to help those who haven't gotten better with standard treatments like diet changes or pelvic floor therapy.
Rouen, FranceAges 18 years+ - NCT06032104Recruiting
Bean supplement study for colon cancer screening patients
This trial tests whether adding a daily bean supplement to your diet can improve colon health. You may be eligible if you are between 30 and 80, overweight, and scheduled for a routine colonoscopy.
Sacramento, CaliforniaAges 30–80 - NCT06052683Recruiting
Comparing radiation side effects for low-risk prostate cancer
This trial compares two types of radiation therapy (SBRT and LDR brachytherapy) for men with low-risk or favorable intermediate-risk prostate cancer. The goal is to see which treatment causes fewer side effects.
Québec, QuebecAges 18 years+ - NCT06266832RecruitingPhase 2
Short-course radiation with immunotherapy and chemo for rectal cancer
This trial tests a combination of short-course radiation, an immunotherapy drug (adebrelimab), and chemotherapy (CAPEOX) before surgery to help preserve the rectum in people with MSS/pMMR ultra-low rectal cancer. The goal is to shrink the tumor enough to avoid removing the rectum.
Hangzhou, ZhejiangAges 18 years+ - NCT06391034RecruitingPhase 2
MRI scan with pyruvate for prostate cancer
This trial uses a special MRI scan (with hyperpolarized pyruvate, a naturally occurring substance) to look at prostate cancer in more detail. It aims to help doctors understand how the cancer is responding to treatment or how it might behave.
San Francisco, CaliforniaAges 18 years+ - NCT06392737Recruiting
AI-guided MRI vs routine MRI for prostate biopsy
This study tests whether an artificial intelligence tool for MRI can improve the results of targeted prostate biopsy, compared to the usual method. It could help diagnose prostate cancer more accurately with fewer needles.
Beijing, Beijing MunicipalityAges 45–85 - NCT06402357RecruitingPhase 2
Focused Ultrasound for Recurrent Prostate Cancer After Radiation
This trial tests if a focused ultrasound treatment can safely and effectively treat prostate cancer that has come back after radiation therapy. The ultrasound uses sound waves to heat and destroy cancer cells in a specific area of the prostate while sparing healthy tissue.
Gainesville, FloridaAges 18 years+ - NCT06427824Recruiting
Health tests for older adults with bladder cancer before bladder removal
This study looks at how a series of health tests (called a comprehensive geriatric assessment) can help doctors plan care for older adults with bladder cancer who are having their bladder removed. The goal is to improve recovery and quality of life.
Chicago, IllinoisAges 65 years+ - NCT06451445Recruiting
Focal IRE treatment for intermediate-risk prostate cancer
This trial tests a new focal treatment called IRE (irreversible electroporation) that uses electrical pulses to destroy prostate cancer cells while sparing healthy tissue. It is for men with intermediate-risk prostate cancer that has not spread outside the prostate gland.
Toronto, OntarioAges 50 years+ - NCT06468332Recruiting
AI learning from MRI and tissue to improve prostate cancer care
This study uses artificial intelligence to look at your MRI scans, tissue samples, and medical records to learn more about prostate cancer and find better ways to treat it. You may join if you've had prostate removal surgery or have advanced prostate cancer.
NovaraAges 18–80 - NCT06482645Recruiting
Testing a new biopsy method for prostate cancer diagnosis
This study is testing a new approach to prostate biopsy that takes samples from around a suspicious area seen on MRI. It aims to see if this method can better detect prostate cancer compared to standard biopsy.
Beijing, Beijing MunicipalityAges 45–85 - NCT06494696Recruiting
PSMA PET/MRI with MRI for prostate cancer risk
This study tests whether a special scan (PSMA PET/MRI) combined with a standard MRI can better detect prostate cancer. It is for men who have not had a biopsy yet and are suspected of having prostate cancer.
Taoyuan CityAges 40–85 - NCT06517901Recruiting
Comparing two MRI-guided biopsy methods for prostate cancer
This trial compares two ways to use MRI images during a prostate biopsy to see which finds cancer better. It looks at 'fusion' biopsy (where a computer combines MRI with live ultrasound) versus 'cognitive' biopsy (where the doctor mentally matches the MRI to the ultrasound).
Burlington, MassachusettsAges 18 years+ - NCT06591819RecruitingPhase 2
Shorter pelvic radiation with HDR boost for prostate cancer
This trial tests a shorter course of radiation therapy (hypofractionated whole-pelvis radiation) combined with a high-dose-rate (HDR) brachytherapy boost for men with high-risk or unfavorable intermediate-risk prostate cancer. The goal is to see if this approach controls cancer while possibly reducing side effects.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06684652Recruiting
Comparing targeted plus standard biopsies for prostate cancer diagnosis
This trial tests whether adding a targeted biopsy to a standard sextant biopsy improves the detection of prostate cancer. It is for men aged 45 to 85 who have a suspicious spot on an MRI of their prostate and have not had a biopsy before.
Beijing, Beijing MunicipalityAges 45–85 - NCT06804785Recruiting
AI-assisted MRI reading for prostate cancer diagnosis
This trial is testing a new 'smart' system that combines artificial intelligence (AI) with doctor oversight to better read prostate MRI scans and guide decisions for men who have not yet had a biopsy. It may help avoid unnecessary biopsies while catching cancer early.
Bethesda, MarylandAges 18–89 - NCT06805123Recruiting
Early feeding after colorectal polyp removal
This trial compares starting to eat right after a colon polyp removal procedure versus waiting a few hours. It may help you resume normal eating sooner after the procedure.
BusanAges 18 years+ - NCT07231627Recruiting
Using AI to improve prostate cancer detection from MRI
This trial tests whether an artificial intelligence (AI) program can help doctors decide when a prostate biopsy is needed. It is for men who have had a prostate MRI that shows either a low-risk (PIRADS 1-2) or uncertain (PIRADS 3) spot, along with a higher-than-normal PSA level. You may qualify if you have certain risk factors like a high PSA density, suspicious digital rectal exam, or family history of prostate cancer.
Little Rock, ArkansasAges 40 years+ - NCT07245745Recruiting
Comparing two types of radiotherapy for prostate cancer
This trial compares adaptive radiotherapy (which adjusts to changes in your body) with conventional radiotherapy for prostate cancer. It aims to see which approach leads to better patient-reported outcomes.
BrusselsAges 18 years+ - NCT07249281Recruiting
New MRI scan for better prostate cancer detection
This study tests a new type of MRI scan (called TDDMRI) that looks at tiny details in prostate tissue to better detect cancer. If you are already getting a prostate MRI, this extra scan may help doctors find cancer more accurately.
Beijing, Beijing MunicipalityAges Any age - NCT07292818RecruitingPhase 1
Hyaluronic acid gel spacer study for cervical cancer radiation
This trial tests if a gel spacer made from hyaluronic acid can protect healthy tissue during radiation for cervical cancer. It may help reduce side effects for patients getting chemoradiotherapy with brachytherapy.
Chapel Hill, North CarolinaAges 18 years+ - NCT07339904Recruiting
Bowel Function After Rectal Cancer Surgery
This study follows people with rectal cancer who have surgery to remove part of the rectum. It looks at how bowel function changes over time, and whether different treatments before surgery affect recovery.
Edegem, AntwerpAges 18 years+ - NCT01194648Recruiting
HIFU treatment for early prostate cancer
This trial studies a focused ultrasound treatment called HIFU for prostate cancer that appears limited to the early stages. It aims to treat cancer within the prostate while avoiding treatment spread to lymph nodes or distant organs.
London, EnglandAges Up to 90 years - NCT01492972RecruitingPhase 3
Lighter radiation, with or without hormone suppression
This Phase 3 trial tests whether giving a smaller amount of radiation (“hypo-fractionated” means fewer, larger sessions) can work as well as standard approaches for intermediate-risk prostate cancer. It also compares adding hormone therapy (“androgen suppression”) to radiation versus using radiation alone.
Scottsdale, ArizonaAges 18 years+
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Common questions
- Are there clinical trials for colorectal (colon or rectal) cancer?
- Yes. Clin2 currently lists 893 recruiting colorectal (colon or rectal) cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colorectal (colon or rectal) cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colorectal (colon or rectal) cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.