Clinical trials
Colorectal (Colon or Rectal) Cancer clinical trials
Below are recruiting colorectal (colon or rectal) cancer clinical trials, each written for real people, not researchers. We’re tracking 867 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04742621Recruiting
Liver transplant for colon cancer that spread only to the liver
This trial studies using a liver transplant to treat colon or rectal cancer that has spread to the liver but not anywhere else. It may help people with limited liver-only spread whose disease hasn’t worsened for a while.
New York, New YorkAges 18–65 - NCT05393609Recruiting
Quality-of-life study during surgery for diverticular disease
This trial studies how people’s quality of life changes around diverticular disease surgery. It may help doctors understand what to expect and how to better support patients before and after surgery.
Randers, Central JutlandAges 18 years+ - NCT05390827Recruiting
Remote health tracking for people with and without cancer
This study uses a smartphone app to collect health data like activity and heart rate over several months, to help understand how cancer and treatment affect patients. It may help improve care for people with cancer and those at risk.
New York, New YorkAges 18 years+ - NCT05043012Recruiting
Testing a special MRI scan for prostate cancer diagnosis
This study checks how well a new prostate MRI scan (using a flexible coil and multiple MRI types) can correctly identify prostate cancer and help with treatment planning. You may be able to help doctors improve prostate imaging before you have surgery.
Houston, TexasAges 18 years+ - NCT04556916Recruiting
Early prostate cancer screening with MRI before biopsy
This study is testing an approach to find prostate cancer earlier in men who may be at higher risk. If you fit the criteria, you may get an mpMRI scan before undergoing a prostate biopsy to check for cancer.
MontpellierAges 40 years+ - NCT02759744Enrolling by invitation
Laser treatment for certain prostate tumors guided by MRI images
This trial tests whether a precisely targeted laser procedure—guided by MRI images—can treat prostate cancer. It may help some men who have a certain type and location of tumor while aiming to avoid nearby sensitive structures.
Bethesda, MarylandAges 18–100 - NCT01492972RecruitingPhase 3
Lighter radiation, with or without hormone suppression
This Phase 3 trial tests whether giving a smaller amount of radiation (“hypo-fractionated” means fewer, larger sessions) can work as well as standard approaches for intermediate-risk prostate cancer. It also compares adding hormone therapy (“androgen suppression”) to radiation versus using radiation alone.
Scottsdale, ArizonaAges 18 years+ - NCT07672860RecruitingPhase 2
UDCA to protect kidneys during partial nephrectomy
This clinical trial is testing whether a medicine called ursodeoxycholic acid (UDCA) can help protect the kidneys during partial nephrectomy (removing only the tumor while keeping the healthy part of the kidney). It is for people with early-stage kidney tumors who will have temporary interruption of blood flow to the kidney during surgery.
Nanjing, JiangsuAges 18–75 - NCT02102477Recruiting
Surgery or radiation for prostate cancer in the pelvis
This trial compares surgery versus radiation for men with locally advanced prostate cancer that has not spread to distant sites. It aims to see which treatment works better and is easier to manage for people like you.
AalborgAges 18–75 - NCT03587480Recruiting
Surgery methods after chemo-radiation for stage 3 rectal cancer
This trial compares two different surgery approaches after chemo-radiation for stage 3 rectal cancer. It aims to see which operation helps control the cancer more effectively while keeping surgery as safe as possible.
Guangzhou, GuangdongAges 18–75 - NCT05689775Recruiting
Robot-assisted reconstruction using tummy muscle flap after surgery
This trial studies a specific way to rebuild the pelvic floor (and sometimes the vagina) after major rectal or anal cancer surgery. It uses robotic surgery and a flap taken from your tummy muscle to help close and reconstruct the area.
OsloAges 18 years+ - NCT02669992Recruiting
Compare closure methods for a loop ileostomy after rectal cancer
This trial studies which technique works best to close a loop ileostomy after rectal cancer surgery. It compares different closure methods to see which is safer and more effective for patients.
GothenburgAges Any age - NCT06204341Recruiting
Finding the best radiation for high-risk prostate cancer
This trial compares different radiation therapy plans for men with high-risk prostate cancer that has spread to the lymph nodes. It aims to find the best way to treat the prostate and the surrounding lymph nodes while minimizing side effects.
Leidschendam, South HollandAges 18 years+ - NCT07755592Recruiting
Using a blood test to find prostate cancer early
This study uses a simple blood test to look for microRNA patterns that may help spot prostate cancer earlier and avoid unnecessary biopsies. If you have elevated PSA or suspicious findings, this test might give more information about your risk.
ShanghaiAges 18 years+ - NCT05629494RecruitingPhase 4
Ibuprofen vs PSA blood test for prostate evaluation
This trial studies whether an anti-inflammatory medicine (ibuprofen) changes prostate-specific antigen (PSA) blood test results to help decide on next diagnostic steps like MRI or biopsy. It may help people with an elevated PSA understand whether follow-up testing is more or less likely to be needed.
Chicago, IllinoisAges 18–80 - NCT07692152RecruitingPhase 3
Immunotherapy vs. chemo for MS anal cancer trial
This trial tests sintilimab (a type of immunotherapy) against mitomycin plus chemotherapy with radiation for anal cancer that hasn't spread. It aims to find a better treatment with fewer side effects.
Beijing, Beijing MunicipalityAges 18–75 - NCT07650344Recruiting
AI Tool to Detect Flat Colon Polyps During Screening
This study tests whether artificial intelligence can help doctors spot certain flat polyps (called sessile serrated lesions) during routine colonoscopy screening. Finding these polyps early may help prevent colorectal cancer.
SingaporeAges 40–80 - NCT07623941Recruiting
Focal Therapy Registry for Localized Prostate Cancer
This registry tracks men with early-stage prostate cancer who choose focal therapy—a targeted treatment that destroys only the cancer area while preserving healthy prostate tissue. The study helps doctors understand how well this approach works and its safety.
New York, New YorkAges 40–85 - NCT07578324Recruiting
TENS to reduce pain during prostate biopsy
This study tests whether TENS (a gentle electrical stimulation applied to the skin) can help reduce pain when combined with numbing medicine during a prostate biopsy procedure. The goal is to see if this may make the biopsy more comfortable for patients.
Gdansk, Pomeranian VoivodeshipAges 40 years+ - NCT07557901Enrolling by invitation
Antibiotics to prevent infection after prostate biopsy
This study tests whether taking antibiotics before a prostate biopsy (a needle procedure to check for cancer) reduces infections. You would receive either standard care or a specific antibiotic plan, and researchers will track any infections that develop.
Banská BystricaAges Any age - NCT07456852RecruitingPhase 1/Phase 2
Can vasodilators help with chemo side effects in GI cancer?
This trial tests two drugs (isosorbide mononitrate and diltiazem) to see if they can prevent blood vessel damage caused by chemotherapy drugs like 5-FU or capecitabine in people with gastrointestinal cancers.
Rochester, MinnesotaAges 18 years+ - NCT06643793RecruitingPhase 2
Irinotecan liposome combo for advanced colorectal cancer
This trial tests a new form of the chemotherapy drug irinotecan (called irinotecan liposome) combined with two other chemo drugs and a targeted therapy (bevacizumab) for people with advanced colorectal cancer that has already been treated with oxaliplatin. The goal is to see if this combination can shrink tumors or slow the cancer's growth.
Nanjing, JiangsuAges 18–75 - NCT07431723Recruiting
Magnetic magnets to connect the intestines during surgery
This trial is testing a new way to connect parts of the large or small intestine using magnets instead of staples or stitches. It may help people who need certain types of colon or rectal surgery recover with less pain and fewer complications.
SantiagoAges 18–75 - NCT07428356Recruiting
Sound waves for liver tumors
This study tests a new, noninvasive treatment called histotripsy that uses sound waves to destroy small liver tumors. It is for people whose liver cancer hasn't spread much and who haven't had success with or can't have surgery or other standard treatments.
SingaporeAges 21–99
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Common questions
- Are there clinical trials for colorectal (colon or rectal) cancer?
- Yes. Clin2 currently lists 867 recruiting colorectal (colon or rectal) cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colorectal (colon or rectal) cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colorectal (colon or rectal) cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.