Clinical trials
Coma clinical trials
Below are recruiting coma clinical trials, each written for real people, not researchers. We’re tracking 16 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06245434Recruiting
Circadian rhythms during coma awakening
This study looks at how the body's internal clock (circadian rhythm) changes as people wake up from a coma. Researchers hope to learn more about recovery patterns to improve care for patients with brain injuries.
Bron, LyonAges 17 years+ - NCT06930261RecruitingPhase 2
Brain dopamine changes after traumatic coma
This study looks at how a traumatic brain injury that causes coma affects the brain's dopamine system. You will get two types of brain scans (MRI and PET) to see changes that might help predict recovery.
ToulouseAges 18–65 - NCT07614074Recruiting
Understanding Recovery from Coma and Unconsciousness
This study follows patients who have been in a coma (deep unconsciousness) for at least 24 hours due to a brain injury. Researchers will track how patients recover over time to better understand which factors help predict who will wake up and how well they'll recover.
San Francisco, CaliforniaAges 18 years+ - NCT07719595Recruiting
Vagus nerve stimulation for coma after brain injury
This trial tests if a gentle electrical stimulation of the vagus nerve (a nerve in the neck) can help people regain consciousness after a severe traumatic brain injury. It is for patients who are in a coma or minimally conscious state, and the treatment is given along with standard ICU care.
Stony Brook, New YorkAges 18 years+ - NCT04445649Recruiting
Find factors to help people regain consciousness after brain injury
This study looks at what predicts recovery of consciousness after certain serious brain injuries, such as stroke or traumatic brain injury. It may help clinicians better identify which patients are more likely to wake up and guide early rehabilitation and care.
Hessisch OldendorfAges 18–85 - NCT05321459Recruiting
Testing outcome prediction in comatose patients after cardiac arrest
This study looks at tests that may help predict outcomes in people who remain in a coma 3 to 7 days after surviving a cardiac arrest. It may help doctors better estimate recovery and guide care decisions.
BobignyAges 18 years+ - NCT05922644Recruiting
Spinal cord stimulation for consciousness recovery after brain bleed
This trial studies whether short-term spinal cord stimulation can help people regain consciousness after an intracerebral hemorrhage (brain bleed). It’s mainly for patients whose brain function tests suggest they are in a minimally conscious state and who are medically stable enough for the procedure.
Beijing, Beijing MunicipalityAges 18–65 - NCT06241482Recruiting
Enhanced recovery after brain surgery in intensive care
This study tests a special recovery program for people with serious brain injuries or strokes who need intensive care. The program focuses on helping you heal faster after surgery.
ShanghaiAges 18–75 - NCT06564662Recruiting
Brain wave test for kids with prolonged seizures
This study uses a quick brain wave test (EEG) to help doctors spot ongoing seizure activity in children who are thought to have status epilepticus, a type of long-lasting seizure. The results may help guide treatment faster.
The Bronx, New YorkAges 2–18 - NCT06549426Recruiting
Treating seizure activity after cardiac arrest
This trial tests a treatment for seizure-like brain activity that can happen after a cardiac arrest. It aims to see if treating these seizures quickly can improve recovery for people who are in a coma.
BrusselsAges 18 years+ - NCT07247669Recruiting
AI phone triage for emergencies
This study tests if artificial intelligence can help identify time-sensitive emergencies like stroke, heart attack, or trouble breathing from recorded phone calls. The goal is to make emergency response faster and more accurate.
Málaga, MálagaAges Any age - NCT07456020Recruiting
Measuring awareness after brain injury in the ICU
This study checks how awake and aware you are using two standard checklists (CRS-R and SECONDs). It's for people with recent brain injuries in intensive care who are still very dependent.
Hessisch Oldendorf, Lower SaxonyAges 18 years+ - NCT07485361Recruiting
Brain scanning in disorders of consciousness
This trial uses a portable brain scanner (fNIRS) to study brain activity in people with disorders of consciousness, like coma or minimally conscious states. It may help doctors better understand and track recovery in these patients. Healthy volunteers are also needed as a comparison group.
Los Angeles, CaliforniaAges 18 years+ - NCT06617377Recruiting
Can MRI predict brain recovery after cardiac arrest?
This study uses brain scans (MRI) to try to predict whether people who are still unconscious after a cardiac arrest will recover. It is looking for adults who are in a coma and have not woken up after being taken off sedation medicines for at least three days.
ToulouseAges 18 years+ - NCT07074678Enrolling by invitation
Predicting recovery in early consciousness disorders
This study uses brain scans to understand how people with severe brain injuries may recover consciousness. It is for patients who have had a recent brain injury and are in a coma, vegetative state, or minimally conscious state.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06681779Enrolling by invitation
Testing mild electrical stimulation for coma exams
This study tests if a mild electrical skin stimulation (like a TENS unit) can be used instead of a painful pinch to check brain function in coma patients. It aims to make the standard coma exam more comfortable and consistent.
Phoenix, ArizonaAges 18 years+
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Common questions
- Are there clinical trials for coma?
- Yes. Clin2 currently lists 16 recruiting coma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.