Clinical trials
Coronary artery disease clinical trials
Narrowing of the arteries that supply blood to the heart. We’re tracking 731 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06489119Recruiting
Studying plaque types in coronary artery disease with advanced imaging
This trial uses advanced imaging (OCT) and single-cell analysis to study different types of plaque in people with coronary artery disease. It aims to understand how these plaque types differ at a cellular level, which could lead to better treatments.
Harbin, HeilongjiangAges 18–85 - NCT06494501RecruitingPhase 3
Preventing heart attacks in middle-aged adults with early plaque
This study tests whether starting cholesterol-lowering treatment early can prevent heart attacks in people aged 30-50 who already have early signs of artery plaque but no history of heart disease.
New York, New YorkAges 30–50 - NCT06496321Recruiting
Comparing two leg vein removal methods for bypass surgery
This trial compares two ways of taking a vein from your leg during heart bypass surgery to see which causes fewer problems. The goal is to find the best method for your recovery.
MontevideoAges 18–70 - NCT06512493Recruiting
South East Netherlands Heart Registry
This is a heart registry that collects information from all patients to get a complete picture of heart care in the region. By including everyone, it aims to improve future treatments without bias.
Heerlen, LimburgAges Any age - NCT06519292Recruiting
Heart side effects from immunotherapy in cancer patients
This trial looks at whether immunotherapy drugs (checkpoint inhibitors) cause heart problems in people with certain cancers. It will help doctors understand who is at risk and how to monitor for side effects.
Amsterdam, North HollandAges 50 years+ - NCT06535568Recruiting
Comparing one vs two blood thinners after heart artery balloon treatment
This trial tests whether taking just one blood thinner (clopidogrel) is as safe and effective as taking two (clopidogrel plus aspirin) for older adults or people at high bleeding risk who have had a drug-coated balloon procedure to open blocked heart arteries.
Milan, MIAges Any age - NCT06541691Recruiting
Aspirin for heart disease patients in polluted air
This study tests if different types of aspirin (coated or chewable) and a special schedule can help people with heart or blood vessel disease when they are exposed to air pollution. If you live in Tehran and have stable heart disease, you may be able to join.
Tehran, Tehran ProvinceAges 18 years+ - NCT06542393RecruitingPhase 2
Blood management for anemic patients having bypass surgery
This trial tests a blood management strategy to help people with anemia who are having coronary artery bypass surgery (CABG). If you qualify, you may receive a treatment to improve your blood counts before surgery, which could reduce the need for transfusions.
São Paulo, São PauloAges 18–80 - NCT06545448Recruiting
Study of planned angioplasty in stable heart disease
This study looks at whether planned angioplasties (a procedure to open blocked heart arteries) are done appropriately for people with long-term stable heart disease. It aims to help doctors make better decisions for patients like you.
São Paulo, São PauloAges 18 years+ - NCT06546761Recruiting
Heart imaging after carotid artery treatment
This study tests whether imaging the heart's arteries with a special CT scan can help find hidden blockages in people who just had treatment for a blocked carotid artery. It aims to prevent future heart problems.
RigaAges 50 years+ - NCT06551662Recruiting
Balloon vs. stent for split artery blockages
This trial compares two ways to open a blocked artery that splits into two branches (a bifurcation): using a balloon coated with medicine (drug-coated balloon, or DCB) versus a drug-eluting stent (DES). The goal is to see which approach works better for patients with this type of blockage.
MilanAges 18 years+ - NCT06559332Recruiting
Heart artery checks during aortic valve replacement
This study tests different ways to check for blocked heart arteries in patients getting a new aortic valve through a tube in the leg. It aims to find the best approach to guide treatment.
BernAges 70 years+ - NCT06567626Recruiting
Decision aid for heart artery treatment choices
This study is testing a new tool to help patients and doctors decide together on the best procedure (like stents or bypass surgery) for blocked heart arteries. It aims to make the decision process clearer and more personalized.
LeicesterAges Any age - NCT06567938Recruiting
Heart artery procedure study for people with kidney disease
This trial uses a special ultrasound camera inside the heart's arteries to guide stent placement for people with chronic kidney disease. The goal is to see if this approach improves outcomes compared to standard methods.
Xi'an, ShaanxiAges 18 years+ - NCT06567795Recruiting
Monitoring heart risk with a wearable sensor in diabetes
This trial tests a wearable chest sensor (called HEMOTAG) to monitor heart events in people with long-standing Type 2 diabetes who also have heart disease or specific diabetes-related complications. The sensor is worn at home for short periods to catch early signs of heart trouble, aiming to improve personalized care.
West Palm Beach, FloridaAges 40 years+ - NCT06568159Recruiting
Sleep apnea treatment in heart patients
This study looks at how well people with heart disease or high heart risk follow their sleep apnea treatment, comparing a mouth device (MAD) to a CPAP machine. It aims to find which treatment works better for daily use.
MontpellierAges 18 years+ - NCT06572267RecruitingPhase 2
Meplazumab for coronary artery disease
This trial tests if meplazumab can help people with chronic coronary syndrome who have stable angina. It focuses on patients with certain fatty deposits around their heart arteries that show up on a special CT scan.
Xi'an, ShannxiAges 18 years+ - NCT06578234RecruitingPhase 4
Comparing Adenosine Doses for Heart MRI
This study will compare different doses of adenosine during a heart MRI to find the best dose for measuring blood flow to the heart muscle. It is for people with known or possible coronary artery disease or heart failure, as well as healthy volunteers.
LundAges 40 years+ - NCT06579807Recruiting
Cardiac rehab for coronary artery disease
This study tests if a cardiac rehabilitation program helps people with coronary artery disease. You can join if you are between 40 and 70, have heart disease (or are a healthy volunteer), and do not have other health issues like heart failure or smoking.
Rio de Janeiro, Rio de JaneiroAges 40–70 - NCT06597851Recruiting
Insulin resistance and heart artery health: a study for chest pain patients
This study looks at how insulin resistance affects tiny heart arteries in people who have chest pain and signs of heart stress on tests, but do not have major blockages in their heart arteries. It aims to understand why some people have heart symptoms even when their main arteries appear clear.
Verona, VRAges 18 years+ - NCT06600178RecruitingPhase 1
Heart medication for women with chest pain and small vessel disease
This trial tests a diabetes medication called SGLT2 inhibitors to see if it can improve blood flow to the heart and reduce chest pain in women who have small vessel heart disease (microvascular dysfunction) but not blocked large arteries. Participants will take the medication and be monitored for symptom relief and heart function improvements.
Charlottesville, VirginiaAges 18 years+ - NCT04968808Recruiting
Find best timing for stent procedure in NSTEMI with multiple vessel disease
This trial compares when to do a stent procedure (PCI) in people with NSTEMI who have disease in more than one coronary artery (non-IRA). It may help doctors choose the safest and most effective timing for treatment to improve outcomes.
GwangjuAges 19 years+ - NCT07091682Recruiting
A trial of a dissolvable heart stent for long blockages
This trial tests a new type of stent made from magnesium that slowly dissolves over time. It is for people who have a long blockage in a heart artery that has not been treated before and may be a good option for those who are stable and have not had a recent heart attack.
ErfurtAges 18–80 - NCT06736899Recruiting
Orbital atherectomy versus standard care for calcified branch blockages
This trial compares a special device called orbital atherectomy to the usual procedure for treating hardened, calcified blockages that occur where a coronary artery branches. It aims to see which approach works better for patients needing a stent.
AlicanteAges 18 years+
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Common questions
- Are there clinical trials for coronary artery disease?
- Yes. Clin2 currently lists 731 recruiting coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.