Clinical trials
Coronary artery disease clinical trials
Narrowing of the arteries that supply blood to the heart. We’re tracking 712 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04679740Recruiting
Magnesium stent used in routine care registry study
This is a registry study that follows people who receive a resorbable magnesium scaffold (a temporary artery support used during procedures). The goal is to learn how the device performs and how patients do over time in real-world use.
CairnsAges 18 years+ - NCT05681702RecruitingPhase 4
Personalizing medicines to reduce bleeding after stent procedure
This trial studies ways to reduce bleeding in people after a stent procedure (PCI) who have been taking two anti-platelet medicines (aspirin plus prasugrel or ticagrelor) for a set amount of time. It may help find a safer plan for preventing blood clots while lowering bleeding risk.
Jacksonville, FloridaAges 18 years+ - NCT05704296Recruiting
Two bypass techniques using leg vein and chest artery
This study compares two ways of using a leg vein and an artery from your chest during coronary artery bypass surgery. It may help doctors learn which approach works best for making the new blood pathways to your heart.
SeoulAges 19 years+ - NCT05618353RecruitingPhase 4
Colchicine before surgery to lower heart and inflammation complications
This trial tests whether taking colchicine around the time of surgery can reduce bad events after surgery in people at higher heart risk. It focuses on helping prevent complications related to inflammation after an operation.
Birmingham, AlabamaAges 18 years+ - NCT05461729Recruiting
Testing a heart rehab timing prediction tool after a heart attack
This study follows people with coronary artery disease who are starting a structured heart rehabilitation program after a heart attack or heart procedures. The trial tests whether it can predict and improve the right timing or planning for cardiac rehab.
Ennepetal, North Rhine-WestphaliaAges 18 years+ - NCT05487612Recruiting
MiECC heart-lung machine vs standard bypass during heart surgery
This trial compares a newer heart-lung machine setup (MiECC) with the usual bypass technique during certain heart operations. It may help see whether MiECC changes outcomes like the need for blood transfusions or recovery after surgery.
TorontoAges 18–85 - NCT05418556RecruitingPhase 4
Comparing antiplatelet strategies after heart stent
This study compares two ways of choosing blood thinners after a heart stent procedure. It aims to see if using an imaging-guided strategy leads to better outcomes than usual care.
Bucheon-siAges 19 years+ - NCT05427370Recruiting
Compare bypass or stent treatment in weak heart patients
This study compares two ways to restore blood flow to the heart—bypass surgery (CABG) or stent procedure (PCI)—in people with a weak pumping heart. It looks at which approach works best when the heart muscle is not pumping well and there are multiple blocked heart arteries.
Los Angeles, CaliforniaAges 18 years+ - NCT05427084RecruitingPhase 2/Phase 3
Canagliflozin to reduce inflammation in heart artery disease
This trial tests canagliflozin to see if it lowers “vascular inflammation” in people with diabetes and stable coronary artery disease. It may help reduce harmful inflammation signals that can raise future heart risk.
Ottawa, OntarioAges 18 years+ - NCT05369442Recruiting
Blood-thinner plan study for people with high bleeding risk after PCI
This trial studies which blood-thinner (antiplatelet) strategy is safest and most effective for people at high risk of bleeding after a procedure called PCI. It also looks at longer-term outcomes and whether adjusting treatment can improve safety without losing heart protection.
Sichuan, SichuanAges Any age - NCT05332262Recruiting
Study to predict heart damage risk during planned angioplasty
This trial focuses on people with stable coronary artery disease who are scheduled for planned angioplasty (PCI). It looks for a “precision medicine” approach to identify who may be at risk for a small heart injury around the procedure, so doctors can better prevent it.
Jacksonville, FloridaAges 18 years+ - NCT02038660Recruiting
Drug-coated balloon treatment registry for narrowed blood vessels
This study records outcomes for people who get a drug-coated balloon used to treat a narrowed blood vessel after a first balloon treatment. It may help doctors understand how well this approach works in everyday care and for different patient needs.
Bucheon-siAges 20 years+ - NCT05111288Recruiting
Testing a pulse field therapy for reduced heart ischemia
This trial studies whether pulse electromagnetic field therapy can improve signs of reduced blood flow to the heart (ischemia) in people who cannot or will not get a coronary procedure during the study. If you already take standard heart medicines, you may be eligible to add this therapy and undergo exercise testing and heart imaging.
Scottsdale, ArizonaAges 18 years+ - NCT05100940Recruiting
Study after a heart procedure complication
This trial looks at what happens after complications during or after a heart procedure called coronary angiography or PCI. It may help improve care and outcomes for people who experience a problem during treatment.
Minneapolis, MinnesotaAges 18 years+ - NCT02039752Recruiting
Registry for adults with multi-vessel heart disease
This study is a registry that collects information about adults with heart disease affecting more than one vessel. It may help doctors better understand how these conditions are managed over time at Asan Medical Center.
SeoulAges 19 years+ - NCT01788592Recruiting
Study of drug-coated stents in routine heart procedure care
This study follows people who need a heart procedure to open narrowed coronary arteries using a drug-coated stent. It aims to see how well these stents work and how people do in everyday clinical practice.
SeoulAges 18 years+ - NCT04604782RecruitingPhase 1/Phase 2
Regadenoson study in children to test safety and dosing
This trial tests how safe regadenoson is in children and how the body handles it after dosing. It also uses a heart “stress test” with MRI (CMR) when doctors feel it’s needed.
ParisAges 4 weeks–18 years - NCT04443530Recruiting
Testing Ultimaster stents in everyday patient care
This trial looks at how safe and effective two specific stents are when doctors use them as part of routine care. You may be a candidate if you’re an adult receiving one of these Ultimaster stents and can follow the study check-in schedule.
ChuncheonAges 19 years+ - NCT04014803RecruitingPhase 4
Aspirin plus one blood thinner versus aspirin plus clopidogrel
This trial compares two common “blood thinner” combinations to prevent problems after a PCI procedure for complex blocked heart arteries. It may help your care team find which combination works better for people with higher-risk artery patterns.
SeoulAges 19–75 - NCT03327961Recruiting
Study of implanted scaffolds with follow-up in adults
This study follows adults who have had at least one scaffold placed to see how they do over time. It also looks at whether people can stick with the required anti-platelet medicines for at least a year, and whether they can be followed for a year.
Agrigento, AgrigentoAges 18 years+ - NCT01524276Recruiting
Registry to track outcomes of Medtronic medical devices
This is a follow-up registry that collects information from people who have (or will receive) an eligible Medtronic device. It helps the company and doctors better understand how the device works in real-world use.
Birmingham, AlabamaAges Any age - NCT01517425Enrolling by invitation
Using blood stem cells to study heart disease traits
This study uses your blood to create special lab cells (induced pluripotent stem cells) to better understand heart-related differences between people with coronary artery disease and generally healthy older adults. It may help researchers learn what biological traits are linked to heart risk and how those traits work.
La Jolla, CaliforniaAges 18 years+ - NCT02013284Enrolling by invitation
Stool test to see if gut microbes predict heart risk
This study looks at your gut bacteria (from a stool sample) to see whether they can help predict heart risk in people being checked for blocked heart arteries. Your results may help researchers understand who is at higher risk and why.
Rochester, MinnesotaAges 18 years+ - NCT02061436Recruiting
Chronic total occlusion procedure registry
This study collects data from patients who are having a procedure to open a completely blocked coronary artery. It may help improve future treatments for this condition.
Phoenix, ArizonaAges Any age
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Common questions
- Are there clinical trials for coronary artery disease?
- Yes. Clin2 currently lists 712 recruiting coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.