Clinical trials
Coronary artery disease clinical trials
Narrowing of the arteries that supply blood to the heart. We’re tracking 731 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07195968Enrolling by invitation
Comparing nitroglycerin and saline for heart artery testing
This trial compares two ways to test blood flow in the heart arteries: one uses a medicine called nitroglycerin, and the other uses salt water. It may help people with partial blockages (50-90%) in their heart arteries, especially if they have not had a recent serious heart attack.
Hsinchu, SelectAges 21 years+ - NCT07158307Enrolling by invitation
Studying a new balloon treatment for small heart arteries
This trial tests a special balloon coated with medicine to treat blocked small arteries in the heart. It may help people who have new blockages and are getting a procedure to open those arteries.
UlsanAges 19 years+ - NCT06898827Enrolling by invitation
Virtual reality distraction therapy for cardiac rehab
This trial tests whether using virtual reality (VR) during cardiac rehabilitation can help distract you from discomfort or anxiety. If you have a heart condition or have had a heart event and are starting rehab, you may be able to join.
MsidaAges 40 years+ - NCT06542575Enrolling by invitation
Home heart rehab with app after stent
This trial tests a home-based program that uses a smartphone app (digital therapy) to help people with high-risk heart conditions after a stent procedure. The goal is to improve recovery through exercise and lifestyle support, all from home.
Chengdu, SichuanAges 18–75 - NCT06190834Recruiting
HDL subtypes and heart disease outlook study
This study looks at how different subtypes of HDL (the 'good' cholesterol) relate to the outlook for people with coronary artery disease. If you have heart artery blockages and your HDL subtypes have been checked, this trial might help understand your prognosis better.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06249568Recruiting
Testing fluid response during heart bypass surgery
This study tests a method to see if your body needs more fluids during heart bypass surgery. After the surgeon opens your chest, they will use a special breathing maneuver to check how well your heart responds to extra fluid, which may help guide your care.
AnkaraAges 18–80 - NCT07053254Recruiting
Studying vein grafts in older heart bypass patients
This trial looks at how vein grafts work in older adults who need coronary artery bypass surgery. It aims to understand why grafts sometimes fail, so doctors can improve treatment.
SeoulAges 19–100 - NCT06125392Recruiting
New Definition for Small Heart Vessel Disease
This trial studies a condition where small heart vessels don't work well. It looks at new ways to define this problem using a special test that measures pressure and blood flow in a heart artery.
Mainz, Rhineland-PalatinateAges 18–90 - NCT07035171Recruiting
Pre-surgery exercise for heart bypass patients
This study tests whether starting a supervised exercise program before your first heart bypass surgery (CABG) is possible and helpful. If you are waiting for elective CABG and speak Danish, you may be able to join a prehabilitation program to get stronger before your operation.
CopenhagenAges 18 years+ - NCT06215248Recruiting
Heart function study in leg artery disease patients
This trial uses ultrasound to check how well the heart pumps in people with blocked leg arteries. It aims to find early signs of heart strain that standard tests might miss.
TartuAges 35–85 - NCT07012070Recruiting
Wearable trackers to improve walking in peripheral artery disease
This trial tests whether using a wearable activity tracker (like a fitness band) can help people with peripheral artery disease walk better and farther without pain. It's designed for people newly diagnosed with leg pain when walking (claudication) and offers a simple way to track and improve your walking.
Hong Kong, Hong KongAges Any age - NCT05640453RecruitingPhase 4
Testing pregabalin or dexmedetomidine for post-surgery delirium
This study compares two medicines—pregabalin and dexmedetomidine—to treat confusion (called delirium) after heart bypass surgery. It aims to see which drug works better to reduce delirium symptoms in older adults after coronary artery bypass surgery.
Tanta, El-Gharbia GovernorateAges 65 years+ - NCT02582021Recruiting
Study of treatments and imaging in women with angina or HFpEF
This trial studies how heart disease affects the heart using heart imaging, and looks at people with chest pain/angina or heart failure with preserved pumping strength (HFpEF). It may help doctors better understand what’s driving symptoms and how best to evaluate these conditions.
Los Angeles, CaliforniaAges 18 years+ - NCT06494163Recruiting
Exercise Training for Women With Heart Disease
This study compares two types of exercise training (high-intensity interval training vs. moderate-intensity continuous training) to see which is better for women with heart disease. You would be assigned randomly to one of the two exercise programs, and the study would last about 6 months.
Ottawa, OntarioAges 18 years+ - NCT07259278Recruiting
Heart rehab program with smart app support
This trial uses a smartphone app to guide exercise for people with coronary heart disease who are at low risk of complications. It aims to help you recover safely at home with remote support from doctors.
Beijing, Beijing MunicipalityAges 18 years+ - NCT03876847Enrolling by invitation
Study genetics in people with spontaneous artery tears
This study looks for genetic (inherited) reasons some people develop SCAD, a sudden tear in a heart artery. It compares people with SCAD to people without it and may help doctors recognize risk and causes.
Ages Any age - NCT05916950Recruiting
Study of a new treatment for blocked leg arteries
This trial studies a device-based treatment approach for people with blocked (narrowed or fully blocked) arteries in the thigh or behind the knee that reduce blood flow to the leg. It may help improve blood flow and walking ability, but you must meet specific artery and imaging requirements.
St. Helena, CaliforniaAges 18 years+ - NCT05972070Recruiting
Telemedicine home cardiac rehab after heart procedure
This trial studies whether cardiac rehabilitation done at home, with help from telemedicine, is safe and helps you stick with the program after a recent heart procedure. It may help you recover with more convenience while still improving heart-related fitness and adherence.
Brookfield, ConnecticutAges 18 years+ - NCT06924593Recruiting
Shunt for carotid artery narrowing
This study tests a new device that is placed through the carotid artery in the neck to temporarily block blood flow during a procedure to open up a narrowed carotid artery. It might be an option for people who have high-risk features that make traditional surgery more challenging.
BeijingAges 18 years+ - NCT07316452Recruiting
Early heart disease risk study for adults under 45
This study looks at what makes heart disease progress in younger adults (18 to 45). If you have symptoms of heart disease and have had a heart CT scan, joining this research might help doctors better predict and manage your condition.
BeijingAges 18–45 - NCT07004452Recruiting
Predicting heart risks in younger adults with early heart disease
This study uses a multi-modal approach to predict adverse events in adults aged 18-45 with premature coronary heart disease. It aims to improve risk prediction and management for younger patients.
BeijingAges 18–45 - NCT06959628Recruiting
Study of a new shunt system for carotid artery blockage treatment
This trial tests a special shunt system to protect your brain during carotid artery stenting. It may help people with severe blockages in the neck artery that supplies blood to the brain.
BeijingAges 18 years+ - NCT07302659Recruiting
Comparing two aortic clamping methods in off-pump bypass
This study compares two ways to clamp the aorta during off-pump heart bypass surgery to see which is safer for your brain and body. If you are having bypass surgery without a heart-lung machine, you may be able to join.
BeijingAges 18 years+ - NCT06193954Recruiting
Vibrating guidewire for chronic heart artery blockages
This trial tests a special vibrating guidewire to help open heart arteries that have been completely blocked for a long time, when standard wires have failed. It may help you if you have a stubborn blockage requiring a gentle approach.
Atlanta, GeorgiaAges 18 years+
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Common questions
- Are there clinical trials for coronary artery disease?
- Yes. Clin2 currently lists 731 recruiting coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.