Clinical trials
Coronary artery disease clinical trials
Narrowing of the arteries that supply blood to the heart. We’re tracking 732 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07258290Recruiting
Freesolve Magnesium Scaffold for Heart Artery Blockages
This trial tests a new dissolvable magnesium scaffold to treat blockages in heart arteries. It is designed for people with stable heart pain or certain recent heart attacks, and it aims to open blocked arteries and then slowly dissolve over time.
Washington D.C., District of ColumbiaAges 18–80 - NCT07724184Recruiting
Treating calcified heart arteries with a stent
This trial tests a way to treat hardened, calcified heart artery blockages using a stent. It may help people who have moderate blockages that haven't been treated before.
AalborgAges 18–90 - NCT07045194Recruiting
Study of Virtue balloon for coronary stent re-narrowing
This trial tests a special balloon to treat narrowed areas inside a previously placed heart stent. It may help by reopening the artery without adding another stent.
Gainesville, FloridaAges 18 years+ - NCT07348341Recruiting
Laser treatment for blocked heart arteries registry
This study collects information from patients with blocked heart arteries who receive a special laser treatment (ELCA) to open the blockage. It will help doctors understand how well this laser works in different situations.
MadridAges 18 years+ - NCT07711106Recruiting
Comparing expert IVUS to standard IVUS for left main artery stenting
This study compares two ways of using a special ultrasound camera (IVUS) inside your heart's main artery during stenting. The goal is to see if a new 'expert' computer system helps the doctor place the stent better than the standard IVUS method. It may help people with blockages at the Y-shaped split of the left main artery.
Saint PetersburgAges 18 years+ - NCT07363161Recruiting
Drug-coated balloon vs. stent for high-risk heart disease
This trial compares two treatments for people with complex coronary artery disease who have high-risk conditions or complicated blockages: a drug-coated balloon (DCB) versus a drug-eluting stent (DES). Both are ways to open up narrowed arteries and keep them open without surgery.
HomburgAges 18 years+ - NCT05634031Recruiting
Study of heart vessel dysfunction seen on heart imaging
This study looks at coronary microvascular dysfunction (small blood vessel problems in the heart) using heart imaging. It may help researchers understand causes of chest tightness with activity and shortness of breath when the main heart arteries are not blocked.
New York, New YorkAges 18 years+ - NCT03209414Recruiting
Study of frailty in heart patients receiving heart care
This trial looks at “frailty,” meaning reduced strength and resilience, in older adults with coronary artery disease who are getting heart care. It may help doctors better understand which patients are more at risk and how care decisions could be improved.
Zabrze, Upper SilesiaAges 65 years+ - NCT03376165Recruiting
Study heart rhythm problems after heart surgery
This trial looks at heart rhythm issues (especially atrial fibrillation) that can happen after certain heart procedures. It may help doctors better predict, prevent, or manage these rhythm problems after surgery.
LilleAges 18 years+ - NCT03378934RecruitingPhase 4
Berberine after stent placement to reduce blood-platelet effects
This trial studies whether berberine changes how strongly your platelets “stick together” after a coronary stent. It may help reduce risk related to clotting while you continue standard heart medicines (aspirin and clopidogrel).
Beijing, Beijing MunicipalityAges 18–70 - NCT03443999Recruiting
Registry to follow patients with a sirolimus stent
This study is a follow-up registry that tracks how people do after doctors place a specific type of drug-eluting coronary stent. It may help doctors understand safety and outcomes of the Supraflex stent in real-world care.
Breda, North BrabantAges 18 years+ - NCT03479580Recruiting
Registry for coronary and small-vessel heart disease in cardiomyopathy
This study enrolls people with certain types of heart muscle diseases to learn how blocked heart arteries and tiny blood vessels affect symptoms and outcomes. It may help researchers better understand these conditions and improve future care.
La TroncheAges 18–100 - NCT03497637Recruiting
Compare two ways to measure artery narrowing during heart procedures
This study compares two pressure-based methods (Vessel-FFR vs standard FFR) to decide how severe a heart artery narrowing is during a coronary angiogram or PCI. It may help patients and doctors choose which narrowings need treatment more accurately.
DresdenAges 18 years+ - NCT03711539Recruiting
Exercise program study to help prevent clogged heart arteries
This trial studies whether lifetime endurance exercise is linked to a lower risk of coronary artery disease (clogged heart arteries). It may help explain which people benefit most from regular endurance activity and who may need different prevention steps.
EdegemAges 45–70 - NCT03850015Recruiting
Ultrasound test to assess heart disease using faster images
This trial studies whether a newer, faster ultrasound imaging method can better assess areas of the heart that may not get enough blood during stress. You may be eligible if you have known coronary artery disease or are considered low risk, and if you can safely undergo the stress ultrasound test.
Harrow, MiddxAges 18 years+ - NCT03908463Recruiting
Heart procedure registry for people who get coronary angioplasty
This trial is a registry that collects health information from adults who undergo a heart procedure called coronary angioplasty. It may help researchers understand outcomes and improve care for future patients undergoing similar treatments.
SeoulAges 19 years+ - NCT03987633Recruiting
Study links health records and samples to understand health gaps
This study asks people affected by a specific illness (or their family member) to share saliva (and sometimes blood) and answer health and quality-of-life questions. The goal is to better understand and reduce health inequality by matching new information with medical records.
Wolverhampton, West MidlandsAges 6 years+ - NCT04011527Recruiting
Registry for heart stent procedure using rotational atherectomy
This study collects information from people who are having a heart procedure called rotational atherectomy to open blocked heart arteries. It helps doctors better understand how the procedure is used and its outcomes.
Bad SegebergAges 18–100 - NCT04014140Recruiting
iFR-guided bypass surgery planning during elective heart surgery
This trial studies whether using a pressure-measurement test called iFR during a pre-surgery heart scan can help guide coronary artery bypass surgery (CABG). It may improve how doctors choose which artery blockages to treat during planned surgery.
London, Greater LondonAges 25–80 - NCT04027244Recruiting
Studying care plans for severe leg blood flow problems
This study looks at how best to manage severe leg ischaemia, a condition where blood flow to the leg is dangerously reduced. It mainly involves patients who are planning an intervention, and some participants may also do special heart imaging tests.
Leicester, LeicestershireAges 18–110 - NCT04124120Recruiting
Single vs multiple bypass grafts for women heart surgery
This study compares outcomes of using one bypass graft versus multiple bypass grafts during coronary artery bypass surgery in women. It aims to see which approach leads to better recovery and heart outcomes for eligible patients.
Los Angeles, CaliforniaAges 18 years+ - NCT04185285Recruiting
Heart procedure registry for people who had stents
This trial is a registry that collects information from people who receive a heart artery procedure (percutaneous coronary intervention) at the study hospital. It mainly helps researchers understand outcomes and care patterns, and it only requires your consent to participate.
FribourgAges 17–120 - NCT04196712Recruiting
Heart artery testing registry during coronary angiography
This trial is a registry that collects information from people undergoing an invasive heart artery test (coronary angiography). It helps researchers understand heart disease and outcomes in real-world patients.
Essen, North Rhine-WestphaliaAges Any age - NCT04220047Recruiting
Surgery changes for preventing irregular heart rhythms during bypass
This trial studies whether removing a small heart pouch area and a specific ligament during off-pump heart bypass surgery improves outcomes. It is meant for people having their first off-pump coronary bypass, without a history of atrial fibrillation.
BeijingAges 18–80
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Common questions
- Are there clinical trials for coronary artery disease?
- Yes. Clin2 currently lists 732 recruiting coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.