Clinical trials
Coronary artery disease clinical trials
Narrowing of the arteries that supply blood to the heart. We’re tracking 732 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04255563Recruiting
Drug-coated balloon for coronary artery disease
This trial studies a balloon treatment coated with medicine (to help keep the artery open) for people with coronary artery disease. You may be a candidate if you are planned to receive this type of procedure and do not have certain key safety risks.
Nanjing, JiangsuAges 18 years+ - NCT04347200Recruiting
Long-term blood-thinner therapy registry for heart disease
This study follows people with known coronary artery disease to understand how long-term “blood thinner” treatments are used and how they affect health over time. You may be asked to share medical information and come in for follow-up to help researchers compare outcomes.
MoscowAges 18 years+ - NCT04375306Recruiting
Testing a heart-pressure ratio to choose bypass surgery plan
This trial studies whether a special heart “pressure/flow ratio” test (measured during the procedure) can help doctors choose the best plan for coronary bypass surgery. It may improve how bypass targets the problem blood vessels, but only if certain heart and health factors fit the study rules.
BonheidenAges 18 years+ - NCT04416581RecruitingPhase 4
Compare two stomach-protecting medicines to prevent bleeding
This trial compares a potassium-competitive acid blocker to a proton pump inhibitor to help prevent stomach or intestinal bleeding in people at high risk who take blood-thinning medicines. It may help reduce dangerous GI bleeding while you stay on heart/stroke medicines.
AnyangAges 19 years+ - NCT04417387Recruiting
Check genetics to improve heart disease risk prediction
This study looks at whether adding genetic information to a standard NHS Health Check can better predict a person’s risk of coronary artery disease (CAD). If you qualify, you may be asked to provide genetic information to help refine future risk estimates.
LeicesterAges 40–74 - NCT04464655Recruiting
10-minute heart MRI protocol for people with heart conditions
This study uses a short, 10-minute heart MRI to check how well it works for people who need a clinically indicated heart scan. It may help streamline heart MRI testing, making exams faster while still providing useful heart information.
Montreal, QuebecAges 18 years+ - NCT04576130Recruiting
ICD study after cardiac arrest from an abnormal heart rhythm
This study looks at an implantable defibrillator (ICD) strategy in people who survived a cardiac arrest caused by an abnormal rhythm (ventricular fibrillation or ventricular tachycardia). It aims to reduce the risk of another dangerous rhythm after the blocked heart arteries are fully treated.
CopenhagenAges 18 years+ - NCT04634240Recruiting
Staged heart bypass plus TAVR versus TAVR alone
This study compares doing a staged coronary bypass (revascularization) along with a valve procedure (TAVR) versus doing TAVR and medical treatment alone. It aims to see which approach better helps people with both aortic valve narrowing and coronary artery disease.
Huntsville, AlabamaAges Any age - NCT04674449Recruiting
Tests a targeted plan for people with chest pain from heart artery disease
This study aims to match people with angina (chest pain from heart artery problems) to the most helpful treatment plan based on their test results. It’s done around the time doctors are planning an invasive heart scan to look at the coronary arteries.
CorkAges 18 years+ - NCT04748237Recruiting
CT heart scan for intermediate-risk chest pain
This study tests whether a special heart CT scan can help evaluate the cause of chest pain in people at intermediate risk for blocked heart arteries. It may help doctors decide what to do next after an emergency room visit.
StockholmAges 18 years+ - NCT04761991Recruiting
CMR vs CT scan for coronary artery disease
This study compares two heart-imaging tests—cardiac MRI (CMR) and CT—to see which better helps evaluate coronary artery disease in people with chest pain. You may be asked to have one of these scans as part of your heart work-up.
Leicester, LeicsAges 18 years+ - NCT04772768Recruiting
Checking problems in vein bypass grafts in people with recurring chest pain
This study looks at how vein bypass grafts are working over time in people who had heart bypass surgery and now have recurring angina (chest discomfort). It may help doctors better understand why symptoms come back and how the heart and grafts change.
AmsterdamAges 18–90 - NCT04814212Recruiting
Testing a drug-coated balloon for people with bleeding risk
This trial looks at whether a “drug-coated balloon” used during a heart procedure (PCI) is safer or better for people who are at higher risk of bleeding while on blood thinners. It may help reduce complications around the time of the procedure in people like you.
Jyväskylä, Central FinlandAges 18 years+ - NCT04827498Recruiting
Testing heart blood-flow problems without clogged arteries
This study looks at how well the heart’s blood vessels work in people who have symptoms of reduced blood flow but no major artery blockage. It uses special heart tests with medicines to check how the vessels respond and may help guide better diagnosis and treatment.
MadridAges 18 years+ - NCT04827316Recruiting
Use CT heart scans to predict outcomes and guide care
This study looks at people who are having a CT scan of their heart because it’s medically needed. Researchers will use the scan results to better predict future cardiovascular outcomes and improve how care decisions are made.
BernAges 18 years+ - NCT04844944Recruiting
Heart registry for adults with heart failure, CAD, or atrial fibrillation
This is a hospital-based study that collects standardized information about adults with specific heart conditions—heart failure, coronary artery disease, or atrial fibrillation. It may help doctors and researchers better understand these diseases and improve future care.
BerlinAges 18 years+ - NCT04939207Recruiting
Test safer, cheaper scans for suspected coronary artery disease
This study compares new imaging methods to see how well they work and whether they can lower costs for people with suspected coronary artery disease. It may help by using different scan approaches while keeping patient safety in mind.
Eindhoven, North BrabantAges 18 years+ - NCT04973579Recruiting
Stent plus heart surgery for high risk carotid patients
This trial looks at whether doing carotid artery stenting at the same time as heart surgery is safe and effective for people at high risk of stroke around the time of surgery. It targets people with significant carotid narrowing who also need heart surgery for specific heart problems.
KrakowAges 18 years+ - NCT04977076Recruiting
Stopping versus continuing blood thinner during heart catheter procedures
This study compares whether you should temporarily stop your blood thinner (DOAC) or keep taking it when you have an elective heart catheter test or procedure (coronary angiography or PCI). It aims to see which approach is safer and better for preventing bleeding and clotting around the procedure.
Heerlen, LimburgAges 18 years+ - NCT04988685Recruiting
Heart artery balloon treatment registry study for adults
This study follows adults with blocked heart arteries who are treated using a special type of balloon (drug-coated balloon) during a procedure. It aims to track real-world outcomes to better understand how well this treatment works for people with new blockages or previously treated vessel narrowing.
Lucerne, Canton of LucerneAges 18 years+ - NCT05044273Recruiting
Study of two new stents and their safety in adults
This study checks how safe and effective two types of heart stents (Synergy XD and Synergy Megatron) are after they are placed. You might consider it if you’re an adult getting one of these stents and can follow required clinic visits.
AnyangAges 19 years+ - NCT05078814Recruiting
Survey of a heart and leg condition’s gene differences
This study collects information to understand how often certain genetic variants (ALDH gene family) show up in people with blocked leg arteries or an acute heart condition. The results may help researchers better understand the biology behind these illnesses.
TainanAges 20 years+ - NCT05100992Recruiting
Bifurcation heart procedure registry for adults
This study is a real-world registry that follows adults who are getting a specific type of heart stent procedure in a forked artery. It helps doctors learn what happens before and after the procedure and improve care.
Minneapolis, MinnesotaAges 18 years+ - NCT05124249Recruiting
Imaging tests to evaluate clogged heart arteries
This study looks at how well special heart imaging and pressure-based tests can evaluate coronary artery disease (clogged heart arteries). If you had testing for suspected heart artery disease, the study may help doctors compare how these measurements work.
GwangjuAges 18 years+
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Common questions
- Are there clinical trials for coronary artery disease?
- Yes. Clin2 currently lists 732 recruiting coronary artery disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.