Clinical trials
Coronary Bifurcation Lesion clinical trials
Below are recruiting coronary bifurcation lesion clinical trials, each written for real people, not researchers. We’re tracking 27 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06971718Recruiting
Study of blood flow in branched heart arteries
This trial tests a new way to measure blood flow in heart arteries that branch. It may help doctors decide the best treatment for blockages where one artery splits into two.
Norwich, NorfolkAges 18 years+ - NCT06618248Recruiting
Sirolimus balloon for heart artery blockages at branches
This study tests a balloon coated with sirolimus (a medicine to prevent re-narrowing) to treat blockages in branch arteries of the heart. It may help patients who need a stent in the main artery but have a side branch that can be treated with this balloon instead of a stent.
Beijing, Beijing MunicipalityAges 18–85 - NCT03450577Recruiting
Bifurcation heart artery registry study for adults
This registry study looks at adults with a specific kind of blockage pattern where a heart artery splits. By collecting information about these cases, the study aims to better understand treatment and outcomes for this condition.
Novosibirsk, Novosibirsk OblastAges 18–100 - NCT07093788Recruiting
Comparing two ways to treat hard calcium in heart arteries
This trial tests two methods for breaking up heavy calcium buildup in heart arteries before placing a stent. It compares a specialized high-pressure balloon to a device that uses shockwaves.
Lianyungang, JiangsuAges 18–80 - NCT06822712Recruiting
Sirolimus-coated balloon for heart artery branch blockages
This trial tests a new balloon coated with sirolimus (a drug that helps prevent re-blockage) for treating blocked arteries at branch points (bifurcations) in the heart. If you have a blocked artery at a branch point, this study may offer a way to treat the side branch without placing a stent there.
Lanzhou, GansuAges 18–80 - NCT06931574Recruiting
Comparing two stent methods for complex heart branch blockages
This trial compares two ways of placing stents in complex blockages in heart artery branches (smaller arteries branching off main ones). It aims to see which technique works better for this specific type of blockage.
IstanbulAges 18 years+ - NCT07711106Recruiting
Comparing expert IVUS to standard IVUS for left main artery stenting
This study compares two ways of using a special ultrasound camera (IVUS) inside your heart's main artery during stenting. The goal is to see if a new 'expert' computer system helps the doctor place the stent better than the standard IVUS method. It may help people with blockages at the Y-shaped split of the left main artery.
Saint PetersburgAges 18 years+ - NCT04896177Recruiting
Sirolimus drug balloon for forked coronary artery blockages
This trial studies a sirolimus drug-coated balloon to treat certain “forked” coronary artery blockages (bifurcation lesions). It aims to reduce re-narrowing of the artery and improve blood flow after the procedure.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT05100992Recruiting
Bifurcation heart procedure registry for adults
This study is a real-world registry that follows adults who are getting a specific type of heart stent procedure in a forked artery. It helps doctors learn what happens before and after the procedure and improve care.
Minneapolis, MinnesotaAges 18 years+ - NCT05731687Recruiting
Balloon or two-stent approach for clogged bifurcation arteries
This trial compares two ways to open a specific type of heart blockage that involves both a main artery and a side branch. It tests whether using a drug-coated balloon (“hybrid strategy”) works as well as using a planned two-stent approach (“stepwise provisional strategy”).
Eindhoven, North BrabantAges 18 years+ - NCT06002932Recruiting
Comparing one-stent with drug balloon vs. two-stents for heart artery branches
This study compares two ways to treat a narrowed heart artery where a smaller branch vessel is also blocked. One approach uses a drug-coated balloon on the side branch, while the other places a second stent. The goal is to see which method works better for patients like you.
Suwon, Gyeonggi-doAges 19 years+ - NCT07596706Recruiting
Comparing two stent techniques for left main branch blockages
This trial compares two ways of placing a stent at the point where the main left artery splits into two branches. It is for people who have a blockage in the very beginning of one of those branches, and it uses advanced drug-eluting stents to see which method works better.
Istanbul, Please SelectAges 18–85 - NCT06551662Recruiting
Balloon vs. stent for split artery blockages
This trial compares two ways to open a blocked artery that splits into two branches (a bifurcation): using a balloon coated with medicine (drug-coated balloon, or DCB) versus a drug-eluting stent (DES). The goal is to see which approach works better for patients with this type of blockage.
MilanAges 18 years+ - NCT06736899Recruiting
Orbital atherectomy versus standard care for calcified branch blockages
This trial compares a special device called orbital atherectomy to the usual procedure for treating hardened, calcified blockages that occur where a coronary artery branches. It aims to see which approach works better for patients needing a stent.
AlicanteAges 18 years+ - NCT06880978Recruiting
Comparing two stent methods for Y-shaped heart blockages
This study compares two stent-placing techniques for people with a specific type of complex heart blockage at a branch point. It aims to see which method is safer and more effective for opening up the artery.
IstanbulAges 18 years+ - NCT07116083Recruiting
Study of a new way to check branch blockages after stent placement
This trial looks at a new method called µQFR to check if there are any significant blockages in the side branches of heart arteries after a single stent has been placed. It aims to see if this method can help doctors decide if more treatment is needed.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07019350Recruiting
Smart stenting for heart artery branch blockages
This trial tests a new way to treat complex blockages in heart arteries where a side branch is also narrowed. It uses a drug-coated balloon to open the side branch, aiming to improve blood flow and reduce the need for repeat procedures.
GwangjuAges 19 years+ - NCT06954714Recruiting
Balloon vs stent for new heart blockages
This trial compares two treatments for new blockages in heart arteries: a drug-coated balloon (a tiny balloon that delivers medicine) versus a drug-eluting stent (a small mesh tube that releases medicine). The study hopes to see which approach keeps the artery open longer and is safer over time.
Busan, BusanAges 19 years+ - NCT06271590Recruiting
Drug-coated balloon for small heart artery blockages
This trial tests a special balloon coated with a drug (sirolimus) to treat blockages in small heart arteries. If the balloon is successful, it may help keep the artery open without needing a permanent stent.
Gilbert, ArizonaAges 18–80 - NCT07022587Recruiting
Dissolving stent with drug for blocked heart arteries
This trial tests a stent that slowly dissolves after opening a blocked heart artery, releasing a drug to prevent reclogging. It may help people with narrowing in one or two spots that are not too hard or twisted.
Xi'an, ShannxiAges 18–75 - NCT07114393Recruiting
Better imaging to guide complex heart artery procedures
This study looks at whether using advanced imaging inside the heart arteries during complex procedures leads to better outcomes compared to current standard practice. If you have had a complex angioplasty (PCI) and your data is in a national heart registry, you may be included.
Eindhoven, North BrabantAges 18 years+ - NCT05908331Recruiting
Balloon treatment test for narrowed stents in heart arteries
This trial tests whether a special drug-coated balloon (“MagicTouch”) can treat re-narrowing inside a previously placed stent. It may help patients whose stent has become blocked again, by improving blood flow and reducing repeat narrowing.
Birmingham, AlabamaAges 18–110 - NCT06742931Recruiting
Balloon vs stent for heart artery blockages in high bleeding risk patients
This trial compares a drug-coated balloon (medicated balloon) to a drug-eluting stent (medicated mesh tube) for treating new blockages in heart arteries. It is designed for patients with a high risk of bleeding who have completed a short course of anti-clotting medication and have been event-free for at least one year.
AnsanAges 19 years+ - NCT04014803RecruitingPhase 4
Aspirin plus one blood thinner versus aspirin plus clopidogrel
This trial compares two common “blood thinner” combinations to prevent problems after a PCI procedure for complex blocked heart arteries. It may help your care team find which combination works better for people with higher-risk artery patterns.
SeoulAges 19–75
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Common questions
- Are there clinical trials for coronary bifurcation lesion?
- Yes. Clin2 currently lists 27 recruiting coronary bifurcation lesion studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary bifurcation lesion trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary bifurcation lesion trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.