Clinical trials
Coronary Heart Disease clinical trials
Below are recruiting coronary heart disease clinical trials, each written for real people, not researchers. We’re tracking 463 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07498231Recruiting
Small heart vessel study for chest pain
This study looks at the tiny blood vessels in your heart (the microcirculation) that can cause chest pain even when the main arteries are open. It aims to better understand and treat this type of chest pain, called chronic coronary syndrome.
BialystokAges 18–75 - NCT07614230RecruitingPhase 4
SGLT2 drugs and heart artery health in diabetes
This study tests whether a diabetes medication called SGLT2 inhibitors can slow the buildup of plaque in heart arteries. Researchers will use special CT scans to track changes in your coronary arteries over time.
Beijing, Beijing MunicipalityAges 18–78 - NCT06014060Recruiting
Shorter vs. longer blood thinner therapy after stenting for high Lp(a)
This trial compares 12 months versus 24 months of dual antiplatelet therapy (two blood thinners) after a stent placement in people with high lipoprotein(a) levels. It aims to see if longer treatment reduces heart risks without increasing bleeding.
Beijing, Beijing MunicipalityAges 18–75 - NCT06969547Recruiting
Heart muscle coordination and microvessel function SPECT study
This study uses a special heart scan (SPECT) to look at how well the heart muscle is squeezing and how well the tiny blood vessels in the heart are working. It may help doctors understand why some people have chest pain even when their main arteries are not blocked.
TomskAges 18–75 - NCT04436978RecruitingPhase 4
Best blood thinner plan for atrial fibrillation after stent
This study compares different blood-thinner (“antithrombotic”) strategies in people with atrial fibrillation or flutter who recently had a stent placed (PCI). It aims to find a plan that lowers clot risk while keeping bleeding risk as low as possible.
AalstAges 18 years+ - NCT03789916RecruitingPhase 3
Aspirin alone versus two blood thinners after heart bypass
This Phase 3 trial compares two strategies to prevent blood clots after heart bypass surgery: aspirin alone versus aspirin plus ticagrelor. It aims to see which approach works better and is safer for people whose bypass does not fully restore blood flow.
RomeAges 18 years+ - NCT05936606Recruiting
Personalized blood thinner choice after stent placement
This trial tests whether tailoring anti-platelet (blood clot prevention) treatment can better protect people at higher risk of heart or blood-vessel problems after a drug-eluting stent. It may help prevent future clots and complications, especially in patients with certain high-risk health conditions or complex stent/scar tissue features.
SeoulAges 19–80 - NCT06075160Recruiting
RFR-guided heart artery treatment for moderate blockages
This trial uses a special pressure wire called RFR to help doctors decide whether a stent is needed for a moderate heart artery blockage. It aims to make sure only the blockages that really need treatment get stented, which may reduce unnecessary procedures.
Bucheon-si, Gyeonggi-doAges 20–90 - NCT07864051Recruiting
Studying blood flow to predict plaque growth in heart arteries
This trial uses special imaging to look at how blood flows through the heart's arteries. It aims to see if certain blood flow patterns can predict where harmful plaque (fatty buildups) may grow, which could help prevent future heart problems.
LondonAges 40 years+ - NCT05728580Recruiting
Study of PCI results at Beijing Friendship Hospital
This trial is for adults who already had a PCI procedure for coronary heart disease and had a successful result. The study looks at how PCI was done in practice and may help improve future treatment and follow-up.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04619355Recruiting
People who had a special heart scan during stent placement
This study follows people who already had a stent put in (PCI) using a special imaging test (NIRS-IVUS) to look at heart outcomes over time. If you agreed and can attend follow-up visits, this registry may help doctors better understand how this imaging-guided approach performs.
SeoulAges 19 years+ - NCT07625488Enrolling by invitation
Heart Disease Risk Follow-up Study for Former Athletes
This study follows up with people who participated in a heart-health study between 2012 and 2014. Researchers will use heart imaging and exercise tests to check your cardiovascular health and learn more about heart disease risk in athletes.
NijmegenAges 45 years+ - NCT04808401Recruiting
Testing how different oxygen levels affect surgery outcomes
This trial studies whether giving higher or lower oxygen during general anesthesia changes heart and lung outcomes after planned (non-emergency) non-heart surgery. It may help doctors choose safer oxygen settings during surgery for people at higher risk for heart problems.
BernAges 18 years+ - NCT07523880Recruiting
Blood Markers Study for Heart Disease and Blood Clot Risk
This study examines new blood markers to predict blood clot and bleeding risks in patients with heart disease taking blood thinners. Understanding these markers may help doctors better predict complications and adjust treatment for individual patients.
Zhengzhou, HenanAges 18 years+ - NCT07444697Recruiting
Erections after heart stent in men with and without heart attack
This study looks at how having a stent placed affects men's ability to have erections. It compares men who had a heart attack with those who had stable chest pain. If you take part, you will fill out short questionnaires about your sexual function and recovery for 6 months.
KirikkaleAges 30–75 - NCT06258681Recruiting
Breathing exercise device for recovery after heart surgery
This trial tests a new breathing exercise device designed to help your lungs recover after heart surgery. It may make your breathing easier and speed up your return to daily activities.
Istanbul, IstanbulAges 40–65 - NCT07380217Recruiting
Using heart pump support for complex high-risk procedures
This trial is testing whether using a special heart pump (PulseCath iVAC2L) during complex, high-risk angioplasty can help people with very weak hearts. It's for people who need a procedure for complicated coronary artery blockages.
AmsterdamAges 18 years+ - NCT07195968Enrolling by invitation
Comparing nitroglycerin and saline for heart artery testing
This trial compares two ways to test blood flow in the heart arteries: one uses a medicine called nitroglycerin, and the other uses salt water. It may help people with partial blockages (50-90%) in their heart arteries, especially if they have not had a recent serious heart attack.
Hsinchu, SelectAges 21 years+ - NCT06509893RecruitingPhase 4
Ticagrelor alone after stent placement
This study tests if a single blood thinner (ticagrelor) works well enough after getting a heart stent, instead of the usual two blood thinners. It may simplify your daily medication routine.
Shiraz, FarsAges 20–80 - NCT07048808RecruitingPhase 2
Gene therapy for chronic chest pain
This trial tests a new gene therapy (XC001) delivered through a thin tube into your heart's blood vessels. It aims to grow new blood vessels to relieve chest pain in people with chronic angina who have no other treatment options.
Birmingham, AlabamaAges 18–85 - NCT07035106Recruiting
Using wearables to track recovery after ICU
This study tests if a wearable device and health summaries can help people recover after a stay in the intensive care unit (ICU). It is for people who have diabetes or heart problems and left the ICU within the last 2 years.
ViennaAges 18–65 - NCT06445608Recruiting
Study of a heart pump for high-risk angioplasty
This trial tests a temporary heart pump (called the KARDION Cory P4) used during a high-risk angioplasty (stenting) procedure. The pump helps keep blood flowing in patients whose heart is weak or who have complex blockages, aiming to make the procedure safer.
Chandler, ArizonaAges 18–90 - NCT06820970Recruiting
Combined therapy for heart artery blockages that weren't fully opened
This trial tests if combining a new heart procedure with a special type of therapy called mindfulness therapy can help prevent heart problems in people with coronary artery disease that could not be fully fixed with stents or surgery.
Zhengzhou, HenanAges 18 years+ - NCT03635255Recruiting
Testing heart disease blood markers to predict heart events
This study looks at tiny molecules in your blood to see how they relate to future heart problems in people with coronary artery disease or other cardiovascular disease. If your results suggest higher or lower risk, it may help doctors better predict who could have adverse cardiovascular outcomes.
TaipeiAges 20 years+
Hear when a new Coronary Heart Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for coronary heart disease?
- Yes. Clin2 currently lists 463 recruiting coronary heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.