Clinical trials
Coronary Heart Disease clinical trials
Below are recruiting coronary heart disease clinical trials, each written for real people, not researchers. We’re tracking 471 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05824520Recruiting
CT blood-flow test guided treatment versus usual care
This trial compares a treatment plan guided by a special CT scan measurement of blood flow (called CT-derived FFR) versus standard medical therapy. It may help doctors choose the safest, most effective treatment based on how restricted blood flow looks on CT.
Hangzhou, ZhejiangAges 18 years+ - NCT06541132Recruiting
Liver fat and heart artery narrowing study
This study looks at whether the amount of fat in your liver, seen on an ultrasound, is linked to the severity of narrowing in your heart arteries. If you had a heart catheterization (angiography) and an abdominal ultrasound, your data may help researchers understand this connection.
Chongqing, Chongqing MunicipalityAges 18–90 - NCT06960902Recruiting
Study of Heart Artery Plaque in Familial Hypercholesterolemia
This study uses a heart CT scan to look for plaque buildup in the arteries of people with familial hypercholesterolemia (a genetic high-cholesterol condition). It aims to understand why some people with FH develop heart disease while others don't.
DijonAges 40 years+ - NCT07498231Recruiting
Small heart vessel study for chest pain
This study looks at the tiny blood vessels in your heart (the microcirculation) that can cause chest pain even when the main arteries are open. It aims to better understand and treat this type of chest pain, called chronic coronary syndrome.
BialystokAges 18–75 - NCT07614230RecruitingPhase 4
SGLT2 drugs and heart artery health in diabetes
This study tests whether a diabetes medication called SGLT2 inhibitors can slow the buildup of plaque in heart arteries. Researchers will use special CT scans to track changes in your coronary arteries over time.
Beijing, Beijing MunicipalityAges 18–78 - NCT06014060Recruiting
Shorter vs. longer blood thinner therapy after stenting for high Lp(a)
This trial compares 12 months versus 24 months of dual antiplatelet therapy (two blood thinners) after a stent placement in people with high lipoprotein(a) levels. It aims to see if longer treatment reduces heart risks without increasing bleeding.
Beijing, Beijing MunicipalityAges 18–75 - NCT06969547Recruiting
Heart muscle coordination and microvessel function SPECT study
This study uses a special heart scan (SPECT) to look at how well the heart muscle is squeezing and how well the tiny blood vessels in the heart are working. It may help doctors understand why some people have chest pain even when their main arteries are not blocked.
TomskAges 18–75 - NCT04436978RecruitingPhase 4
Best blood thinner plan for atrial fibrillation after stent
This study compares different blood-thinner (“antithrombotic”) strategies in people with atrial fibrillation or flutter who recently had a stent placed (PCI). It aims to find a plan that lowers clot risk while keeping bleeding risk as low as possible.
AalstAges 18 years+ - NCT03635255Recruiting
Testing heart disease blood markers to predict heart events
This study looks at tiny molecules in your blood to see how they relate to future heart problems in people with coronary artery disease or other cardiovascular disease. If your results suggest higher or lower risk, it may help doctors better predict who could have adverse cardiovascular outcomes.
TaipeiAges 20 years+ - NCT04619355Recruiting
People who had a special heart scan during stent placement
This study follows people who already had a stent put in (PCI) using a special imaging test (NIRS-IVUS) to look at heart outcomes over time. If you agreed and can attend follow-up visits, this registry may help doctors better understand how this imaging-guided approach performs.
SeoulAges 19 years+ - NCT07380217Recruiting
Using heart pump support for complex high-risk procedures
This trial is testing whether using a special heart pump (PulseCath iVAC2L) during complex, high-risk angioplasty can help people with very weak hearts. It's for people who need a procedure for complicated coronary artery blockages.
AmsterdamAges 18 years+ - NCT06662500Recruiting
Shockwave balloon for hard heart blockages trial
This trial tests a new balloon catheter that uses sound waves to break up hard calcium blockages in heart arteries. It may be an option for people with stable chest pain or who have recovered from a recent heart attack, and who have a single, tough blockage.
La Jolla, CaliforniaAges 18 years+ - NCT06448637Recruiting
Drug balloon vs. medicated stent for large heart arteries
This study compares two treatments for new blockages in large heart arteries: a drug-coated balloon (a balloon that releases medicine) versus a drug-coated stent (a small mesh tube). The goal is to see which one better helps the artery stay open and function normally.
BarcelonaAges 18 years+ - NCT05946629Recruiting
Drug-coated stent trial for narrowed heart arteries
This trial studies a drug-coated balloon (plus standard heart medicines) to treat a specific type of blockage in the heart arteries in people who need an intervention. It may help keep the artery open and prevent the narrowing from coming back, depending on how well you match the detailed heart and medication requirements.
Jonesboro, ArkansasAges 18 years+ - NCT03789916RecruitingPhase 3
Aspirin alone versus two blood thinners after heart bypass
This Phase 3 trial compares two strategies to prevent blood clots after heart bypass surgery: aspirin alone versus aspirin plus ticagrelor. It aims to see which approach works better and is safer for people whose bypass does not fully restore blood flow.
RomeAges 18 years+ - NCT04520126Recruiting
Olive extract for blood vessel and heart function after heart procedures
This trial tests whether an olive extract supplement (Olivomed) improves how your blood vessels, heart, and circulation work. It focuses on people with stable or recently treated coronary heart disease and certain cholesterol patterns.
Athens, AtticaAges 18–70 - NCT04604782RecruitingPhase 1/Phase 2
Regadenoson study in children to test safety and dosing
This trial tests how safe regadenoson is in children and how the body handles it after dosing. It also uses a heart “stress test” with MRI (CMR) when doctors feel it’s needed.
ParisAges 4 weeks–18 years - NCT04808401Recruiting
Testing how different oxygen levels affect surgery outcomes
This trial studies whether giving higher or lower oxygen during general anesthesia changes heart and lung outcomes after planned (non-emergency) non-heart surgery. It may help doctors choose safer oxygen settings during surgery for people at higher risk for heart problems.
BernAges 18 years+ - NCT04927429Recruiting
MRI study to improve heart imaging
This trial helps develop and fine-tune MRI scans that look at the heart and blood vessels. It may help people with heart-related symptoms or conditions by improving how MRI images are created and interpreted.
Washington D.C., District of ColumbiaAges 18–100 - NCT05618353RecruitingPhase 4
Colchicine before surgery to lower heart and inflammation complications
This trial tests whether taking colchicine around the time of surgery can reduce bad events after surgery in people at higher heart risk. It focuses on helping prevent complications related to inflammation after an operation.
Birmingham, AlabamaAges 18 years+ - NCT05728580Recruiting
Study of PCI results at Beijing Friendship Hospital
This trial is for adults who already had a PCI procedure for coronary heart disease and had a successful result. The study looks at how PCI was done in practice and may help improve future treatment and follow-up.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05762952RecruitingPhase 1
Dapagliflozin study for heart micro-blood-flow symptoms in women
This early-phase study tests whether dapagliflozin can improve tiny blood-vessel function in women who have heart-ache-like symptoms but no major blockage on heart scans. If it works, it may help symptoms related to “microvascular” heart circulation problems.
Charlottesville, VirginiaAges 18–99 - NCT05936606Recruiting
Personalized blood thinner choice after stent placement
This trial tests whether tailoring anti-platelet (blood clot prevention) treatment can better protect people at higher risk of heart or blood-vessel problems after a drug-eluting stent. It may help prevent future clots and complications, especially in patients with certain high-risk health conditions or complex stent/scar tissue features.
SeoulAges 19–80 - NCT05998694Recruiting
Monitoring a new aortic heart valve for safety and effectiveness
This trial tests how well a new replacement heart valve works and how safe it is. You might qualify if you need a planned first-time aortic valve replacement and are 60-70 years old (or younger if you cannot take blood thinners).
Kemerovo, Kemerovo OblastAges 60–70
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Common questions
- Are there clinical trials for coronary heart disease?
- Yes. Clin2 currently lists 471 recruiting coronary heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.