Clinical trials
Coronary Heart Disease clinical trials
Below are recruiting coronary heart disease clinical trials, each written for real people, not researchers. We’re tracking 463 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07174206Recruiting
Smartwatch monitoring for heart patients
This trial tests a smartwatch tool to track heart rhythm and detect problems in people with heart disease. It may help find irregular heartbeats early during routine checkups.
São Paulo, São PauloAges 22 years+ - NCT07130994Recruiting
Testing a new less invasive mitral valve replacement (SATURN)
This trial tests a new, less invasive device called the SATURN system to replace a severely leaky mitral heart valve without open-heart surgery. It is for people who are too high-risk for traditional surgery and are willing to take blood thinners.
Los Angeles, CaliforniaAges 18 years+ - NCT06490250Recruiting
Breathing vs. movement exercises for hypertrophic cardiomyopathy
This study compares two types of gentle exercises—breathing muscle training and a traditional Chinese movement practice called Baduanjin—to see which helps people with hypertrophic cardiomyopathy feel better and improve their daily life. If you have a thickened heart muscle but are stable and have mild symptoms, you may be able to join.
IstanbulAges 18 years+ - NCT06891456Recruiting
Pulsed field ablation for ventricular tachycardia after heart attack
This trial tests a new type of energy (pulsed field ablation) to treat a fast heart rhythm called ventricular tachycardia that happens after a heart attack. The goal is to stop the dangerous rhythm without damaging nearby healthy tissue.
Cleveland, OhioAges 18 years+ - NCT06854458Recruiting
Stress heart MRI for better diagnosis of heart artery disease
This study uses a special stress heart MRI to measure blood flow and find blockages in the arteries that supply your heart. It is for people with chest pain or abnormal EKG results who have risk factors for heart disease, to help doctors diagnose and treat coronary artery disease more accurately.
San Francisco, CaliforniaAges 35–85 - NCT06587204Recruiting
Digital study for heart health in Black and Hispanic adults
This study uses a smartphone app to help Black and non-White Hispanic adults with heart or blood sugar conditions. It aims to make research easier to join from home and understand why some groups don't participate.
Miami, FloridaAges 18 years+ - NCT04779008Recruiting
Remote arm treatment to help blood flow after heart bypass
This trial studies whether a simple, at-home type of treatment using brief arm blood-flow changes can improve blood flow to the heart and outcomes after CABG (heart bypass surgery). It may help some people recover better by protecting the heart around the time of surgery.
Zhengzhou, HenanAges 18–80 - NCT06325800Recruiting
Heart and blood vessel health registry
This study collects information from people at risk for heart disease, stroke, or kidney problems to better understand how to prevent these conditions. If you join, you'll be helping doctors learn more about how to keep blood vessels healthy.
Santiago de Compostela, A CoruñaAges 18 years+ - NCT06145035RecruitingPhase 2
Stem cells from cord blood for heart failure
This trial tests whether stem cells from donated umbilical cord blood can improve heart function in people with heart failure caused by blocked arteries. You'll receive one or more infusions of these cells through a vein.
Miami, FloridaAges 21–85 - NCT05152888RecruitingPhase 4
Testing a cholesterol drug to improve heart blood flow on scans
This trial studies whether lowering LDL (“bad cholesterol”) with a PCSK-9 inhibitor (evolocumab) improves blood flow to the heart, measured by special PET scans. It’s for people over a certain age who have stable coronary artery disease and a higher risk of heart problems.
Boston, MassachusettsAges 50–90 - NCT05786417RecruitingPhase 4
Medication comparison for older adults with stable heart pain
This trial tests which heart medications work best for older adults who have stable angina (predictable chest pain) and multiple other long-term health problems. You may be asked to start or adjust medications and attend regular follow-up visits to see which approach controls symptoms and outcomes.
New Haven, ConnecticutAges 65 years+ - NCT04505865Recruiting
Mindfulness program to reduce inflammation in heart disease
This trial studies whether a mindfulness (stress-reducing) program can lower “vascular inflammation” (inflammation in blood vessel walls) in people with stable coronary disease. It may help by improving stress and related inflammation markers while you stay on your usual heart medicines.
Boston, MassachusettsAges 45–65 - NCT04162171Recruiting
SBRT treatment study for steady heart rhythm VT
This study looks at using SBRT (high-precision radiation) to treat a dangerous, steady heart rhythm called monomorphic VT. It is meant for people who keep having VT even after prior ablation attempts and after trying a class III “rhythm-stabilizing” medicine.
Halifax, Nova ScotiaAges Any age - NCT07439133RecruitingPhase 3
Comparing new heart scan with standard tests for coronary disease
This trial is testing a new imaging agent called XTR004 to see if it can accurately find blockages in the heart's arteries. If you have suspected or confirmed stable coronary heart disease, this study may offer a less invasive way to diagnose your condition.
BeijingAges 18–80 - NCT06864234RecruitingPhase 4
Beta-blockers for chest pain without blocked arteries
This trial tests if beta-blocker medication improves blood flow and reduces resistance in the tiny blood vessels of the heart in people who have chest pain but no major blockages in their arteries.
Aalst, FlandersAges 18 years+ - NCT06076551Recruiting
Sex differences in small blood vessel problems of the heart
This study looks at how small blood vessels in the heart work differently in men and women who have chest pain but no major blockages in their main heart arteries. The goal is to better understand and treat these smaller vessel issues.
SeoulAges 20–80 - NCT06558474Recruiting
Optimizing angioplasty with balloon expansion after stent placement
This trial looks at a technique called post-dilatation, where a balloon is used after placing a stent to make sure it's fully open. It may help people who are having angioplasty (a procedure to open blocked heart arteries). Doctors want to see if using this step more often leads to better results.
Eindhoven, North BrabantAges 18 years+ - NCT06114615Recruiting
Remote monitoring after heart treatment to prevent future events
This trial tests whether digital tools can help monitor patients after a stent procedure to lower the chance of another heart problem. It aims to make follow-up care easier and more effective.
Sacramento, CaliforniaAges Any age - NCT05845489RecruitingPhase 4
Clopidogrel to prevent heart problems from minor artery plaque
This trial tests whether clopidogrel (a blood-thinning medicine) can prevent future heart attacks or strokes in people who have early, “subclinical” plaque in their heart arteries. You may be considered if scans show plaque but not major artery blockage that needs a procedure.
Seoul, OtherAges 40 years+ - NCT05700877RecruitingPhase 4
Screening and treatment for silent heart artery disease in type 2 diabetes
This trial tests a screening and intervention approach for “silent” coronary artery disease (heart artery narrowing without major symptoms) in people with type 2 diabetes. It may help prevent future heart problems by finding higher-risk cases early and starting the right treatment plan.
OdenseAges 55–75 - NCT06960902Recruiting
Study of Heart Artery Plaque in Familial Hypercholesterolemia
This study uses a heart CT scan to look for plaque buildup in the arteries of people with familial hypercholesterolemia (a genetic high-cholesterol condition). It aims to understand why some people with FH develop heart disease while others don't.
DijonAges 40 years+ - NCT05824520Recruiting
CT blood-flow test guided treatment versus usual care
This trial compares a treatment plan guided by a special CT scan measurement of blood flow (called CT-derived FFR) versus standard medical therapy. It may help doctors choose the safest, most effective treatment based on how restricted blood flow looks on CT.
Hangzhou, ZhejiangAges 18 years+ - NCT04545112Enrolling by invitation
Testing a new heart bypass graft in people needing multi-vessel CABG
This study tests a new way to connect a bypass graft during heart bypass surgery for people with blocked heart arteries. The goal is to see if the new graft can be safely placed and works well enough to improve outcomes compared with the standard approach.
LeuvenAges 18 years+ - NCT07865377Recruiting
Resveratrol supplement for heart disease in postmenopausal women
This study tests whether a supplement called resveratrol can positively affect estrogen-related markers in postmenopausal women with stable coronary artery disease. It may help understand how this supplement could support heart health.
São Paulo, São PauloAges 45–70
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Common questions
- Are there clinical trials for coronary heart disease?
- Yes. Clin2 currently lists 463 recruiting coronary heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.