Clinical trials
Couples clinical trials
Below are recruiting couples clinical trials, each written for real people, not researchers. We’re tracking 97 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05433129Recruiting
Test of brain blood-flow control using near-infrared light
This study uses a non-invasive light test on the forehead to measure how your brain regulates its blood flow. It’s meant to help researchers understand brain circulation control in healthy people.
Winnipeg, ManitobaAges 18 years+ - NCT05140525RecruitingPhase 3
BPA plus CTEPH medicines to improve heart strain
This trial tests whether starting specific medicines for CTEPH and then doing balloon pulmonary angioplasty (BPA) can improve how well the right side of the heart is working. It may help people who cannot have surgery (PTE) and are newly starting CTEPH/PAH-targeted treatment.
Durham, North CarolinaAges 18 years+ - NCT05175300Recruiting
Vitamin E hip implant for young, active hip replacements
This study tests a hip replacement implant that uses Vitamin E–doped material to see how well it works for young, active adults. It’s meant for people who need a total hip replacement, and compares outcomes over follow-up visits.
LyonAges 18–65 - NCT03746964Recruiting
MRI study of the heart’s aorta before planned surgery
This study uses a special MRI scan to measure how the ascending aorta (a large blood vessel) moves and behaves before planned surgery. It may help doctors better understand the mechanics of an aortic aneurysm and improve future surgical planning.
DijonAges 18 years+ - NCT06777277Recruiting
Couple therapy for low sexual desire or arousal
This study tests a type of talk therapy for couples where one partner has a sexual interest/arousal disorder (low desire or difficulty getting aroused). The therapy helps partners work together to improve their sexual relationship.
Vancouver, British ColumbiaAges 18 years+ - NCT07108049Recruiting
Couples program to strengthen relationships and mental health
This trial tests a program for married couples in rural India that combines relationship building with economic empowerment. It aims to improve mental health and family well-being through six group sessions.
Mumbai, MaharashtraAges 18 years+ - NCT07574619Recruiting
HIV Prevention Choices for Women in Uganda: Couples Study
This research tests a tool that helps women and their partners make informed decisions about PrEP (a daily pill that prevents HIV). The study involves healthcare workers, patients, and leaders in Uganda to improve how women choose and use HIV prevention.
KampalaAges 18 years+ - NCT07096271Recruiting
Relationship education for military couples
This study tests a relationship education program designed for military couples. It aims to help couples strengthen their bond and improve communication through a retreat.
Bethesda, MarylandAges 18 years+ - NCT07683299Recruiting
New heart monitoring during bypass surgery
This study tests a new way to monitor your heart and blood flow during heart surgery that uses a heart-lung machine. The goal is to see if this integrated approach helps doctors make better decisions during the operation.
Medellín, AntioquiaAges 18 years+ - NCT07663812Recruiting
Motivational program for stress in pregnant couples
This study tests whether motivational techniques can help pregnant women and their partners feel less stressed and better able to express emotions. It is for couples who are in the second trimester of a low-risk pregnancy.
Yozgat, CenterAges 18 years+ - NCT06481696Recruiting
Resveratrol to improve IVF outcomes for unexplained infertility
This study tests whether a natural supplement called resveratrol can improve the success of IVF or ICSI for couples with unexplained infertility. You will take resveratrol during your IVF cycle to see if it helps with egg quality and pregnancy rates.
PalermoAges 18–40 - NCT06639932Recruiting
Wellness intervention for Chinese male couples with different HIV status
This study tests a wellness program for male couples in Hong Kong where one partner is HIV-positive and the other is HIV-negative. It aims to help couples improve their relationship and health together.
Xiamen, FujianAges 18 years+ - NCT07203417Recruiting
Online program for couples with different sex drives
This study tests an online education program for couples who feel they have different levels of sexual desire, and it causes at least one partner distress. The goal is to see if the program helps improve relationship satisfaction.
Vancouver, British ColumbiaAges 19 years+ - NCT06929975Enrolling by invitation
Podcast training to reduce birth fear in couples
This study tests whether listening to podcasts about birth can help reduce fear in expecting couples. It is for first-time mothers and their partners who are in the second trimester of pregnancy.
AğrıAges 19–35 - NCT06895603Recruiting
New cuff to measure blood flow during heart procedures
This trial tests a new upper-arm cuff that may measure your heart's blood flow without needing an extra tube in your heart. If you already need a special heart catheter and a wrist arterial line, this study will see if the cuff works just as well.
Charlottesville, VirginiaAges 18 years+ - NCT06758115Recruiting
Brain and Muscle Study for Teens with Scoliosis
This study looks at how the brain and muscles work together in teens with spinal curves (scoliosis). It uses skin sensors and brain wave tests to understand muscle control, which may help improve treatments.
HangzhouAges 10–18 - NCT07371312Recruiting
Couples' outcomes after unsuccessful PGD cycles
This study looks at couples who tried for a baby using PGD (a way to check embryos for genetic diseases before pregnancy) but did not have a baby as a result. It wants to understand what happened next for these couples and how they felt about the process.
ClamartAges 18 years+ - NCT06276530Recruiting
Lung surgery: large incision vs. robotic approach and breathing
This study compares how different types of lung surgery (a large incision vs. robotic-assisted small cuts) affect your posture and breathing. It aims to help doctors choose the best approach for recovery.
ParisAges 18 years+ - NCT07209683Recruiting
Near-infrared light therapy for brain function in adults
This study tests whether shining a special near-infrared light on the head can improve how well your brain works and how clearly you think. It is for healthy younger and older adults who want to help find new ways to support brain health.
Oklahoma City, OklahomaAges 21–85 - NCT06131931Recruiting
HIV prevention study for Latino male couples
This study tests a program to help Latino male couples stay healthy and prevent HIV. It focuses on couples where one or both partners are Latino, and at least one partner has had unprotected anal sex recently.
Orlando, FloridaAges 18–100 - NCT07603245Recruiting
Sleep and Blood Pressure Help for Couples
This study tests whether a sleep improvement program for couples can help lower blood pressure and improve overall health. You and your partner would learn new sleep habits together over several months.
New York, New YorkAges 30–65 - NCT07263750Recruiting
Haptonomy for bonding and reducing childbirth fear in first-time parents
This study tests if haptonomy—a gentle touch and communication method for the baby in the womb—helps first-time parents feel more connected to their baby and less afraid of childbirth.
Merkez, SivasAges 19–35 - NCT04298255Recruiting
Testicular injection therapy for certain causes of male infertility
This trial studies a special lab procedure where selected immature sperm cells are injected to help infertile couples achieve pregnancy. It is designed for couples where the man has a specific type of sperm-making problem found during a testicular sperm extraction.
Winston-Salem, North CarolinaAges 18 years+ - NCT07727265Recruiting
Sepsis and blood vessel injury study
This trial is testing a new approach to understand how sepsis (a severe infection) damages blood vessels. It looks at tiny particles released by cells and a protein called PLIN3 to see if they can help protect blood vessels in patients with sepsis.
Nanjing, JiangsuAges 18–80
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Common questions
- Are there clinical trials for couples?
- Yes. Clin2 currently lists 97 recruiting couples studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a couples trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a couples trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.