Clinical trials
Critical Care clinical trials
Below are recruiting critical care clinical trials, each written for real people, not researchers. We’re tracking 183 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06150326Recruiting
Medical honey for wound treatment in intensive care
This trial tests whether medical honey can help heal wounds like bedsores, cuts, or surgical openings in intensive care patients. If you have a fresh wound that meets the size requirements, you may be able to join.
AngersAges 18 years+ - NCT06027684Recruiting
Intensive care decisions, survival, and dying well
This study talks to adults who have been in an intensive care unit (ICU) to understand their views on life-sustaining treatments, end-of-life wishes, and when they would want less or more care. It aims to improve how doctors and families make these hard decisions together.
ManchesterAges 18 years+ - NCT07384585Recruiting
Light therapy study for children in the ICU
This study tests whether light therapy can help children in the pediatric intensive care unit (ICU) feel better and recover. A parent or guardian must be at the bedside and speak English.
Columbus, OhioAges 4–17 - NCT07077174Recruiting
Permissive lung-protective ventilation for critically ill patients on a breathing machine
This trial tests whether a more lenient approach to lung-protective ventilation can improve outcomes for patients who need a breathing machine (ventilator) in the intensive care unit. It aims to find a balance that is safer for the lungs while still being effective.
AlmeloAges 18 years+ - NCT06576895Recruiting
Nutrition study in critically ill adults
This study looks at how nutrition is given to adults in the intensive care unit (ICU). It aims to understand current practices and may help improve care for future patients.
Melbourne, VictoriaAges 18 years+ - NCT07631221Recruiting
Protein Amount in Nutrition for Critically Ill Kidney Patients
This study tests whether different amounts of protein in tube feeding or IV nutrition affect kidney recovery in patients admitted to the intensive care unit (ICU) with kidney injury. The goal is to find the best protein level to help kidneys heal while patients are critically ill.
Buenos Aires, Buenos AiresAges 18 years+ - NCT07716787Recruiting
Brain monitoring during breathing therapy in critically ill patients
This study looks at how a breathing machine setting (called PEEP) affects blood flow in the brain. If you or your loved one is in the ICU with a serious brain injury and is on a breathing machine, this trial could help doctors understand how to make breathing therapy safer for the brain.
Dongying, ShandongAges 18 years+ - NCT05671614Recruiting
Prevent muscle stem cell failure after critical illness
This trial studies ways to improve recovery of skeletal muscle in people who have been very sick in the ICU. It focuses on preventing problems with the body’s muscle “repair cells” after critical illness.
Prague, Czech RepublicAges 18 years+ - NCT07457554Recruiting
Can respiratory quotient help ICU patients on ventilators?
This study looks at whether using a simple measurement called the respiratory quotient (a sign of how your body is using fuel) can help doctors make better decisions for patients on a breathing machine in the ICU. It may lead to safer, more personalized care.
Poznan, WielkopolskaAges 18–85 - NCT06920173RecruitingPhase 2
Low-dose vasopressors for shock in the ICU
This study tests whether giving low-dose blood pressure medicines through a standard IV (instead of a larger central line) is safe and effective for patients with shock in the intensive care unit.
Kingston, OntarioAges 18 years+ - NCT07130929Recruiting
Electrical stimulation for muscle weakness after severe stroke
This trial tests if a gentle electrical stimulation technique, called functional electrical stimulation, can help patients recover muscle strength after a severe stroke that left them weak in the arms and legs. It may offer a new way to aid rehabilitation in the early months after stroke.
Florence, FIAges 18–80 - NCT06997822Recruiting
Recovery program for ICU survivors
This trial tests a program to help people who were on a breathing machine in the ICU recover after leaving the hospital. It uses a smartphone app to guide your recovery at home.
TaipeiAges 18 years+ - NCT06652126Recruiting
Immune status and ICU infections study
This study looks at how having a weakened immune system affects the risk of getting infections with hard-to-treat bacteria in the ICU. Depending on your immune status, you may be placed in a group that helps doctors understand who is most at risk.
LilleAges 18 years+ - NCT04180397RecruitingPhase 4
Removing extra fluid in critically ill ICU patients with overload
This trial studies a medicine strategy to remove extra fluid from the body in ICU patients who have fluid overload. It aims to see whether controlled fluid removal is safer and better for recovery than usual care.
SydneyAges 18 years+ - NCT06434194Recruiting
Stent study for severe leg pain or wounds
This trial tests a new stent to improve blood flow in blocked leg arteries causing severe pain or tissue loss. It may help if you have a long blockage in the upper leg but not below the knee.
New York, New YorkAges 19 years+ - NCT03753412Recruiting
Rehab program for adults after ICU recovery on ECMO
This trial looks at a recovery and rehabilitation approach for adults who were very sick and needed a machine called ECMO to support breathing and heart function. It may help people regain strength and function after a severe ICU illness.
LondonAges 18 years+ - NCT07141420Enrolling by invitation
Smartphone tool to help ICU recovery
This study tests whether a smartphone tool can help people recover from the long-term effects of being in the ICU. You might be eligible if you had a recent ICU stay and are comfortable using a smartphone.
Guiyang, GuizhouAges 18–100 - NCT07307027Recruiting
Feeding plan for children in intensive care
This study tests a step-by-step feeding plan (enteral nutrition) for children in the pediatric ICU to see if it improves their recovery. It might help if your child is critically ill and can receive nutrition through a tube.
Cairo, AbbasiaAges 1 month–16 years - NCT06766461RecruitingPhase 4
Optimizing antibiotic dosing in ICU patients with septic shock
This trial checks if giving higher doses of beta-lactam antibiotics (a type of strong antibiotic) right from the start helps people in the ICU with septic shock. It aims to find the best dose to fight the infection quickly.
RotterdamAges 18 years+ - NCT06513130Recruiting
Checkup after ICU for adults 75 and older
This study looks at how well older adults (75+) do after leaving the intensive care unit. It will test a simple checkup done at discharge to see if it helps doctors plan better care.
StrasbourgAges 75 years+ - NCT07032987Recruiting
Improving sedation with a new care plan for ICU patients
This trial tests a new sedation protocol for adults in intensive care who need strong pain relief or sedation medicines. It aims to make sedation safer and more comfortable, and includes people on ECMO (a heart-lung machine) or a ventilator (breathing machine) for severe breathing problems.
London, LondonAges 18–100 - NCT05551325Recruiting
Resetting sleep timing for ICU patients to support recovery
This study tests a “sleep chronobundle,” a set of sleep and light-timing steps, to improve daily sleep-wake timing in people in the ICU on breathing or blood-pressure support. It also checks whether the body’s sleep rhythms are more aligned during critical illness and over time.
New Haven, ConnecticutAges 18 years+ - NCT06683781Recruiting
Breathing machine settings and weaning success study
This study looks at how breathing machine settings and monitoring can help predict if a patient will successfully come off the ventilator. It may help doctors choose better settings for patients who are ready to try breathing on their own.
Buenos AiresAges 18–100 - NCT07262320Recruiting
Kidney treatment in Latin American ICUs
This study looks at how dialysis (renal replacement therapy) is used for patients in intensive care units (ICUs) with severe acute kidney injury in Latin America. Your participation can help improve care for people with kidney problems.
CochabambaAges 18 years+
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Common questions
- Are there clinical trials for critical care?
- Yes. Clin2 currently lists 183 recruiting critical care studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critical care trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critical care trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.