Clinical trials
Critically Ill Patients clinical trials
Below are recruiting critically ill patients clinical trials, each written for real people, not researchers. We’re tracking 295 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06179771Recruiting
Filter during dialysis or ECMO for severe illness
This study tests a special filter (HA380 column) used during dialysis or ECMO to remove harmful substances from the blood. It is for critically ill patients with severe infection, injury, or breathing problems who also need kidney or lung support.
Leicester, LeicestershireAges 18–65 - NCT06014801RecruitingPhase 2/Phase 3
Comparing low vs. medium continuous dialysis for kidney injury in the ICU
This study compares two intensities (low vs. medium) of continuous dialysis for people with sudden kidney failure in the ICU. It aims to find which level of treatment works best for critically ill patients.
Sendai, MiyagiAges 18 years+ - NCT04265703Recruiting
Ultrasound-guided line placement for hard-to-access veins
This study tests a specific ultrasound-guided technique to place a central venous catheter (a medical access line) when jugular veins are difficult to access. It may help reduce failed attempts and improve safety in people who need this kind of line for medical care.
GuadalajaraAges 18–80 - NCT04180397RecruitingPhase 4
Removing extra fluid in critically ill ICU patients with overload
This trial studies a medicine strategy to remove extra fluid from the body in ICU patients who have fluid overload. It aims to see whether controlled fluid removal is safer and better for recovery than usual care.
SydneyAges 18 years+ - NCT04047784Enrolling by invitation
Using EBUS to help diagnose a blood clot in the lungs
This study looks at whether a procedure called EBUS (a camera passed through the airway) can help doctors diagnose an acute pulmonary embolism—a sudden blood clot in the lungs—in critically ill, intubated ICU patients. If you’re eligible, EBUS may be done during bronchoscopy as part of your usual care to help confirm or rule out the diagnosis.
Los Angeles, CaliforniaAges 18 years+ - NCT03451968Recruiting
Amino acid levels in long ICU stays after surgery or trauma
This study measures amino acids (building blocks from food) in people who are critically ill after surgery or trauma while they stay in the ICU for more than a week. It also compares results with healthy adults to better understand how critical illness affects nutrition needs.
Petah TikvaAges 18 years+ - NCT03244293Recruiting
Using a brain monitoring number to grade sepsis severity
This trial tests whether a bedside monitoring number called BIS can help sort sepsis into severity levels. If you have sepsis in the ICU, it may help clinicians track how serious it is and guide care.
Dalian, DalianAges Any age - NCT04404400RecruitingPhase 3
Hydrocortisone and fludrocortisone for critical illness hormone shortage
This Phase 3 trial tests whether giving hydrocortisone plus fludrocortisone to critically ill ICU patients with suspected “corticosteroid insufficiency” can improve outcomes without relying on steroids already being used. It may help patients whose bodies aren’t making enough stress hormones during severe illness.
GarchesAges 18 years+ - NCT06822231Recruiting
High-tech rehab for acute neuromuscular diseases
This study tests a high-tech rehab program using robots and advanced tools to help people recover from acute neuromuscular diseases. It aims to see if this approach improves leg strength and mobility better than standard care.
BariAges 18–80 - NCT06721923Recruiting
Comparing protein delivery methods in critically ill children
This study looks at whether giving protein continuously or all at once is better for children in intensive care. The goal is to find the most effective way to support recovery.
Vancouver, British ColumbiaAges 1–11 - NCT01913938Recruiting
Testing treatment for severe inflammation in very ill adults
This trial looks at how to treat a severe, whole-body immune overreaction (“hemophagocytosis”) in adults who are critically ill. You might be considered if blood counts are low (white blood cells and platelets) and if you are already receiving a growth-factor medicine (rhG-CSF).
UlmAges 18–90 - NCT07642076RecruitingPhase 4
L-carnitine supplement for critically ill liver disease patients
This study tests whether adding L-carnitine (a naturally occurring compound) to standard care helps people with serious liver disease who are in the intensive care unit. L-carnitine may help the body use energy better and reduce complications from liver failure.
Shibīn al KawmAges 18 years+ - NCT07362862Recruiting
Electrical muscle stimulation to prevent ICU weakness
This trial tests a wearable device that uses mild electrical pulses to stimulate leg muscles, helping prevent muscle weakness in ICU patients with severe infections. It may help you recover strength faster and avoid long-term disability.
Rochester, MinnesotaAges 18–85 - NCT07032987Recruiting
Improving sedation with a new care plan for ICU patients
This trial tests a new sedation protocol for adults in intensive care who need strong pain relief or sedation medicines. It aims to make sedation safer and more comfortable, and includes people on ECMO (a heart-lung machine) or a ventilator (breathing machine) for severe breathing problems.
London, LondonAges 18–100 - NCT06867354Recruiting
Breathing difficulty in obese patients during weaning from ventilator
This study looks at how often obese patients have trouble breathing when doctors try to remove the breathing tube (weaning) in the ICU. The goal is to understand what causes this and how it affects recovery.
Paris, ParisAges 18 years+ - NCT06039501Recruiting
The Family Perspectives Project Pilot Trial
This study looks at how to improve communication between families and the care team when a loved one is on a breathing machine in the intensive care unit. It may help families feel more supported and involved in care decisions.
Los Angeles, CaliforniaAges 18 years+ - NCT04588311RecruitingPhase 3
Epoetin to improve outcomes in severe trauma ICU patients
This trial tests epoetin alfa (a blood-building medicine) to help reduce death and severe disability in critically ill trauma patients in the ICU. You may be considered if your ICU team expects a longer stay and the timing after injury is early.
Camperdown, New South WalesAges 18–75 - NCT04166877RecruitingPhase 4
Magnesium drip to reduce pain in ICU trauma patients
This trial tests whether a magnesium infusion can better control pain in adults who have serious injuries and need intensive care. It compares magnesium as part of pain treatment to standard pain care to see if pain improves and stays controlled.
Sacramento, CaliforniaAges 18 years+ - NCT05713877RecruitingPhase 2
Melatonin to treat confusion in ICU patients
This Phase 2 trial tests whether melatonin can reduce delirium, a sudden confusion that can happen in the ICU. If you qualify, you may be given melatonin to see if it improves alertness and comfort during an expected longer ICU stay.
Montreal, QuebecAges 18 years+ - NCT05198167Recruiting
HOFA versus hydrocolloid dressings to prevent bedsores
This trial compares two types of skin protection to prevent pressure sores (bedsores) in people who must lie face-down (prone) in the ICU. It may help by reducing new sores from constant pressure in common injury areas.
Majadahonda, MadridAges 18 years+ - NCT06651879Recruiting
Ultrasound airway check in severe preeclampsia patients for C-section
This study compares two ways of using ultrasound to look at the airway in women with severe preeclampsia who need a C-section under general anesthesia. It aims to find which technique is better, so doctors can prepare more safely for your breathing tube placement.
Cairo, Cairo GovernorateAges Any age - NCT07188350Recruiting
Electrical muscle stimulation for patients on a breathing machine
This trial tests whether low-level electrical pulses to the leg muscles can help prevent weakness in patients who need a breathing tube (ventilator) for more than 48 hours. It aims to see if this treatment helps patients recover faster.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT03793257Recruiting
ECMO patient registry for adults in Australia and New Zealand
This is a research registry for adults who need a breathing and/or heart support machine called ECMO while in the hospital. It collects information to better understand who receives ECMO and how patients do over time.
Canberra, Australian Capital TerritoryAges 18 years+ - NCT07802379Recruiting
Tube feeding tolerance with different blood pressure medications in the intensive care unit
This study looks at how critically ill patients on a breathing tube and receiving nutrition through a tube tolerate their feeding, depending on the dose of medications given to manage their blood pressure. It aims to see if feeding works well while patients are on these medications.
IstanbulAges 18 years+
Hear when a new Critically Ill Patients trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for critically ill patients?
- Yes. Clin2 currently lists 295 recruiting critically ill patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critically ill patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critically ill patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.