Clinical trials
Critically Ill Patients clinical trials
Below are recruiting critically ill patients clinical trials, each written for real people, not researchers. We’re tracking 317 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07323472Recruiting
Body positioning and breathing in critically ill patients on ventilators
This study tests whether turning patients on their side affects their breathing and lung health. It aims to improve care for people who need a breathing machine.
Recife, PernamuAges 18 years+ - NCT07367113Recruiting
Finger sensor guided fluids for skin health in older ICU patients
This study tests if using a finger sensor to guide fluid therapy can prevent skin failure in older ICU patients with sepsis or shock. It compares usual care to personalized fluid management.
Nantong, JiangsuAges 65 years+ - NCT01068990Recruiting
Testing how to identify pneumonia germs in ICU patients
This study looks at how well doctors can detect and identify the cause of new pneumonia in people in the medical intensive care unit (ICU). It may help improve how pneumonia is diagnosed and treated in critically ill patients.
SeoulAges 16 years+ - NCT02299921Recruiting
Alcohol and drug effects on immunity in ICU breathing patients
This study looks at how alcohol and other drugs can affect the body’s immune system in people who are very sick in the ICU due to breathing problems. It may help doctors better understand immune changes during critical illness and respiratory failure.
Aurora, ColoradoAges 18–90 - NCT07417969Recruiting
Albumin with furosemide for fluid overload in ICU
This study tests whether giving a medicine called albumin together with a water pill (furosemide) helps ICU patients who have too much fluid in their body and are making very little urine. The goal is to see if this combination can improve urine output and protect kidney function.
Querétaro City, QuerétaroAges 18–100 - NCT07447791Recruiting
Comparing low vs standard dialysis in ICU patients
This trial compares a lower dose versus a standard dose of continuous kidney replacement therapy (CRRT) for critically ill patients with acute kidney injury (AKI — sudden kidney failure). It aims to see if lower doses are safe and effective.
London, Greater LondonAges 18 years+ - NCT07000526RecruitingPhase 4
Inhaled sedation for critically ill patients on breathing machines
This trial compares inhaled isoflurane sedation to standard propofol sedation in deeply sedated patients on ventilators. It aims to see if inhaled sedation improves outcomes.
Orihuela, AlicanteAges 18–80 - NCT07499401Recruiting
Fluid response test in ICU patients with vein congestion
This study looks at how tiny blood vessels respond to extra fluids in ICU patients who have vein congestion. It helps doctors understand if giving more fluid is helpful or harmful for you.
Ancona, ItalyAges 18 years+ - NCT07571317Recruiting
Predicting breathing tube removal success in ICU patients
This study tests whether two simple breathing measurements can predict whether patients in the ICU are ready to have their breathing tube removed. If successful, it could help doctors make safer decisions about when patients can breathe on their own.
Istanbul, IstanbulAges 18 years+ - NCT07611721Recruiting
Testing a glucose monitor in critically ill surgery patients
This study tests whether a wearable glucose monitor (Dexcom G7) works well in patients in intensive care after major abdominal surgery or organ transplant who need insulin therapy. The monitor measures blood sugar continuously to help doctors manage insulin doses more safely.
PragueAges 18 years+ - NCT07653321Enrolling by invitation
Kidney injury in critically ill patients
This study looks at acute kidney injury in patients who are very sick in the intensive care unit (ICU). It may help doctors better understand and manage kidney problems in these patients.
BeijingAges 18 years+ - NCT07306091Enrolling by invitation
Tracheostomy tube removal in critically ill patients
This trial studies the process of removing a tracheostomy tube from critically ill patients who are ready. It focuses on making sure patients can breathe on their own and swallow safely before the tube is taken out.
BursaAges 18 years+ - NCT07164781Enrolling by invitation
Probiotics for preventing infections in ICU patients
This trial tests whether probiotics (good bacteria) can help prevent serious infections in critically ill patients in the ICU. If you are very sick and in the ICU, you may be able to join — as long as you don't have certain conditions like cancer or a weakened immune system.
Banhā, Qalyubia GovernorateAges 18 years+ - NCT06977555Enrolling by invitation
Talking with ICU patients on a breathing machine
This study looks at how nurses and doctors communicate with patients who are awake but on a breathing machine (ventilator) in the intensive care unit (ICU). The goal is to improve communication and make the experience better for patients.
OsloAges 18 years+ - NCT06904001Enrolling by invitation
Early warning model for sepsis in critically ill patients
This trial is building a tool to predict sepsis, a life-threatening response to infection, in intensive care patients. It may help doctors act faster to prevent complications.
Wenzhou, ZhejiangAges 18–99 - NCT06677502Enrolling by invitation
Cerebrolysin for delirium in ICU patients
This trial tests a medicine called Cerebrolysin to see if it helps reduce confusion and agitation (delirium) in patients who are critically ill and being treated in the ICU. It may be an option for you if you are over 18 and have delirium symptoms.
Lubin, Lublin VoivodeshipAges 18–100 - NCT04404400RecruitingPhase 3
Hydrocortisone and fludrocortisone for critical illness hormone shortage
This Phase 3 trial tests whether giving hydrocortisone plus fludrocortisone to critically ill ICU patients with suspected “corticosteroid insufficiency” can improve outcomes without relying on steroids already being used. It may help patients whose bodies aren’t making enough stress hormones during severe illness.
GarchesAges 18 years+ - NCT06721923Recruiting
Comparing protein delivery methods in critically ill children
This study looks at whether giving protein continuously or all at once is better for children in intensive care. The goal is to find the most effective way to support recovery.
Vancouver, British ColumbiaAges 1–11 - NCT06822231Recruiting
High-tech rehab for acute neuromuscular diseases
This study tests a high-tech rehab program using robots and advanced tools to help people recover from acute neuromuscular diseases. It aims to see if this approach improves leg strength and mobility better than standard care.
BariAges 18–80 - NCT01913938Recruiting
Testing treatment for severe inflammation in very ill adults
This trial looks at how to treat a severe, whole-body immune overreaction (“hemophagocytosis”) in adults who are critically ill. You might be considered if blood counts are low (white blood cells and platelets) and if you are already receiving a growth-factor medicine (rhG-CSF).
UlmAges 18–90 - NCT07642076RecruitingPhase 4
L-carnitine supplement for critically ill liver disease patients
This study tests whether adding L-carnitine (a naturally occurring compound) to standard care helps people with serious liver disease who are in the intensive care unit. L-carnitine may help the body use energy better and reduce complications from liver failure.
MenoufiaAges 18 years+ - NCT04166877RecruitingPhase 4
Magnesium drip to reduce pain in ICU trauma patients
This trial tests whether a magnesium infusion can better control pain in adults who have serious injuries and need intensive care. It compares magnesium as part of pain treatment to standard pain care to see if pain improves and stays controlled.
Sacramento, CaliforniaAges 18 years+ - NCT04588311RecruitingPhase 3
Epoetin to improve outcomes in severe trauma ICU patients
This trial tests epoetin alfa (a blood-building medicine) to help reduce death and severe disability in critically ill trauma patients in the ICU. You may be considered if your ICU team expects a longer stay and the timing after injury is early.
Camperdown, New South WalesAges 18–75 - NCT05198167Recruiting
HOFA versus hydrocolloid dressings to prevent bedsores
This trial compares two types of skin protection to prevent pressure sores (bedsores) in people who must lie face-down (prone) in the ICU. It may help by reducing new sores from constant pressure in common injury areas.
Majadahonda, MadridAges 18 years+
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Common questions
- Are there clinical trials for critically ill patients?
- Yes. Clin2 currently lists 317 recruiting critically ill patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critically ill patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critically ill patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.