Clinical trials
Depressed clinical trials
Below are recruiting depressed clinical trials, each written for real people, not researchers. We’re tracking 1,419 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05533138Recruiting
Online therapy to treat depression during pregnancy
This trial tests an internet-based version of CBT, a structured talking therapy, for depression during pregnancy. It may help by teaching practical skills to reduce depressive symptoms while you stay connected to your maternity mental health clinic.
StockholmAges 18 years+ - NCT06005194Recruiting
Exercise therapy via telehealth for depression after brain injury
This study tests whether an exercise program delivered through video calls can help treat major depression in people who have had a traumatic brain injury. If you are at least one year past your injury and have symptoms of depression, you may be able to join.
Seattle, WashingtonAges 18–64 - NCT07684911Recruiting
Long-term effects of TMS for depression
This study looks at how well the benefits of transcranial magnetic stimulation (TMS) last over time for people with depression that didn't get better with other treatments. It also uses brain scans to find markers that might predict who will keep doing well.
RennesAges 18 years+ - NCT06668688Recruiting
Testing a school mental health website
This study looks at how users naturally interact with a website called 'ich Bin Alles @Schule' (I Am Everything @school). It aims to understand the user experience, which may help improve the site for students.
MunichAges Any age - NCT07657234RecruitingPhase 1/Phase 2
Brain stimulation for depression in older adults
This study tests whether a non-invasive brain stimulation technique called transcranial direct current stimulation (tDCS) can help treat depression in people aged 60 and older. tDCS uses a mild electrical current to gently stimulate the brain and may improve mood when added to your current depression treatment.
Dallas, TexasAges 60 years+ - NCT07654179Recruiting
Metformin for depression with obesity: a genetic study
This trial tests if adding metformin to antidepressants helps people who have both depression and obesity. It also looks at genetic factors that might affect treatment response.
Rawalpindi, Punjab ProvinceAges Any age - NCT07621237RecruitingPhase 2
TNX-102 SL for Major Depressive Disorder
This study tests whether a new medication called TNX-102 SL can reduce depression symptoms better than a placebo (inactive pill). You'll take the medication daily and have regular check-ins to see how you're doing.
Phoenix, ArizonaAges 18 years+ - NCT07617467Recruiting
Group therapy for emotional distress in young people
This trial tests whether group-based therapy (Acceptance and Commitment Therapy, or ACT) can help young people manage anxiety, depression, and stress. The therapy teaches skills to accept difficult feelings while living according to your values.
Arendal, AgderAges 16–25 - NCT07610928Recruiting
Stress management and gentle movement for Asian Americans with depression
This study tests whether learning stress management and gentle movement (like Tai Chi or Qigong) can help Asian Americans with depression and physical symptoms. It may offer a way to feel better that you can do from home in online group sessions.
Boston, MassachusettsAges 18 years+ - NCT07577947Recruiting
Digital tracking to help treat pregnancy and postpartum depression
This study tests whether wearing an Apple Watch and using a smartphone app can help doctors better understand and treat depression during pregnancy and after birth. You'll receive depression treatment through the study while the app and watch track your daily patterns.
Los Angeles, CaliforniaAges 18 years+ - NCT07572526Recruiting
Brain Stimulation to Improve Sleep and Mood in Depression
This study tests a non-invasive brain stimulation technique called tDCS (transcranial direct current stimulation) to see if improving sleep can help reduce depression symptoms. You'll do short stimulation sessions at home and track your sleep and mood.
New York, New YorkAges 18–65 - NCT07569198RecruitingPhase 2
Ketamine plus therapy for depression with suicidal thoughts
This study tests whether ketamine (a medication) combined with a specific type of therapy called DBT can help people with treatment-resistant depression and borderline personality disorder who are having thoughts of suicide. You would receive ketamine infusions alongside structured therapy sessions over 6 months.
Toronto, OntarioAges 18–70 - NCT06732089Recruiting
Digital help for stubborn depression
This trial tests a digital program (smartphone app or website) to help people with tough-to-treat depression. If you are already receiving advanced treatments like rTMS, ketamine, or ECT at St. Michael's Hospital, you may be able to join and see if this extra digital support improves your mood.
Toronto, OntarioAges 18 years+ - NCT07474974Recruiting
Can Eye Cells Predict TMS Success for Depression?
This study tests whether a specific type of eye cell can predict how well transcranial magnetic stimulation (TMS) works for treating depression. TMS is a non-invasive brain stimulation method that may help people with depression that hasn't responded to other treatments.
Porto, Porto DistrictAges 18–65 - NCT07416747Recruiting
Probiotic supplement with talk therapy for mild to moderate depression
This study tests whether adding a probiotic supplement to supportive talk therapy helps improve symptoms of mild to moderate depression. It may offer an additional option for people who are not currently taking antidepressant medication.
CréteilAges 18–65 - NCT07210112RecruitingPhase 2
Psilocybin and Trazodone for tough-to-treat depression
This trial tests if taking psilocybin (a psychedelic drug) with trazodone (an antidepressant) can help people whose depression hasn't improved with at least two standard antidepressants. If you have treatment-resistant depression, this study might be an option.
ParisAges 18 years+ - NCT07159347Recruiting
Daily stress and app for depressed children
This study aims to understand what daily stressors look like in children with signs of depression. Your child would use a smartphone app and answer questions to help design a game-like tool that teaches emotion management skills.
München, BavariaAges 8–12 - NCT07151846Enrolling by invitation
Using phone data to predict depression
This study uses your smartphone and a Fitbit to track mood patterns and see if they can predict depression. You may join as someone with a mood disorder, as a healthy volunteer, or as someone at higher risk for mood problems.
Seoul, Seongbuk-guAges 19–75 - NCT07117058Recruiting
Anxiety and depression screening for young cancer survivors
This study tests a quick tool to identify anxiety or depression in children, teens, and young adults who have finished intensive cancer treatment and are now in remission. It aims to help doctors provide better mental health support.
AngersAges 7–25 - NCT07111390Recruiting
Home-based light therapy for major depression
This trial tests whether a special light you can use at home can help treat major depression. It's a 60Hz light that you turn on and off repeatedly. If you're 24–65, have depression, and take a stable antidepressant, you may be able to participate.
New York, New YorkAges 24–65 - NCT07113548Recruiting
Personalized online treatment for depression
This trial tests an online program tailored to your needs for treating depression. You'll get a personalized treatment plan that you can access from your smartphone, without needing to visit a clinic.
OdenseAges 18 years+ - NCT07026461RecruitingPhase 4
TMS for depression: comparing two brain stimulation methods
This trial compares two types of transcranial magnetic stimulation (TMS) to see which works better for people with depression. TMS uses magnetic pulses to stimulate brain areas involved in mood regulation.
ÖrebroAges 18 years+ - NCT06968390Recruiting
Faster TMS for depression during pregnancy or after childbirth
This trial tests a faster form of TMS (brain stimulation) for people with depression who are pregnant (14-34 weeks) or within one year of giving birth. It aims to see if the treatment is safe and well-tolerated.
Boston, MassachusettsAges 18–55 - NCT06860165Recruiting
Mood tracking app study for adults with depression
This study tests a smartphone app (EmoDTx) that monitors mood in people with unipolar depression. It aims to see if the app can provide helpful digital measurements of your mood.
Changé, FranceAges 18 years+
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Common questions
- Are there clinical trials for depressed?
- Yes. Clin2 currently lists 1,419 recruiting depressed studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depressed trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depressed trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.