Clinical trials
Dexmedetomidine clinical trials
Below are recruiting dexmedetomidine clinical trials, each written for real people, not researchers. We’re tracking 191 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07131579Enrolling by invitation
Dexmedetomidine via IV for knee surgery pain
This trial tests adding a medicine called dexmedetomidine to the numbing IV used during knee surgery. It aims to see if it provides better pain relief after surgery under spinal anesthesia.
Al MansurahAges 18–60 - NCT06859892RecruitingPhase 4
Drug combo study for better sleep after major surgery
This study tests whether a combination of two medicines, dexmedetomidine and esketamine, can help improve sleep problems after major non-heart surgery. You may be eligible if you are having planned surgery lasting at least one hour and will use a pain pump after surgery.
BeijingAges 18 years+ - NCT07327905Recruiting
Lidocaine or dexmedetomidine for pain during weight-loss surgery
This trial compares two medicines given through an IV during sleeve gastrectomy (weight-loss surgery) to see which provides better pain control. It may help patients have a smoother recovery with less discomfort.
AlexandriaAges 20–50 - NCT07611890RecruitingPhase 4
Comparing two medications to reduce heart stress during cardiac surgery
This trial tests whether dexmedetomidine or lignocaine better prevents dangerous heart-rate and blood-pressure changes when a breathing tube is placed during heart surgery. If you're having cardiac surgery and are at high risk for heart complications, this study may help protect your heart during the procedure.
Rawalpindi, Punjab ProvinceAges 18–65 - NCT03596424Recruiting
Testing ketamine and dexmedetomidine during lung surgery
This trial studies whether the anesthesia medicines ketamine and dexmedetomidine can improve care during elective lung (video-assisted) surgery. It may help with comfort during and after the operation, depending on how these medicines affect pain and recovery.
Montreal, QuebecAges 18–80 - NCT04289142RecruitingPhase 4
Testing memory effects of dexmedetomidine during heart surgery
This study looks at how a sleep medicine called dexmedetomidine affects thinking and memory after heart surgery. It compares cognitive outcomes over time to see if this sedation choice changes long-term brain function.
Vancouver, British ColumbiaAges 60 years+ - NCT07640516Recruiting
Pain Relief Comparison for Amputation Surgery in High-Risk Patients
This study compares two medications (dexmedetomidine and fentanyl) mixed with a numbing agent to see which works better for blocking pain during above-knee amputation surgery in patients with serious heart or lung disease. Both drugs are already used in anesthesia, and this trial tests which combination is safest and most effective for you.
CairoAges 18 years+ - NCT05168280Recruiting
Dexmedetomidine during brain surgery to prevent confusion in seniors
This trial tests whether giving a medication called dexmedetomidine during selective brain surgery can help prevent postoperative delirium, a sudden episode of confusion, in older adults. If you qualify, the study team would give the medication during the operation and compare outcomes after surgery.
Beijing, Beijing MunicipalityAges 65 years+ - NCT05195034Recruiting
Dexmedetomidine to prevent confusion after awake brain surgery
This trial looks at whether a medication called dexmedetomidine can reduce “postoperative delirium,” a temporary period of confusion after awake brain surgery. If you have the type of surgery the study focuses on, this could help your recovery and mental clarity afterward.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05672225Recruiting
Dexmedetomidine IV pain pump during major abdominal surgery
This trial studies a two-part pain pump given through a vein during major laparoscopic abdominal surgery to help control pain with general anesthesia. It may help by improving comfort while also avoiding certain side effects for people who can safely receive the study medicine.
SeoulAges 20 years+ - NCT06067958RecruitingPhase 3
Nose spray medicine for pain during eye exams in preemies
This study tests a nose spray medicine (dexmedetomidine) to help reduce pain and discomfort in premature babies who need eye exams for retinopathy of prematurity (a condition that can affect vision). The goal is to see if the spray works better than the usual care for calming babies during the exam.
Be’er Ya‘aqov, CenterAges 4 weeks+ - NCT06133712Recruiting
Injection treatment for carpal tunnel pain
This trial tests whether a local injection of three medications (dexmedetomidine, ozone, and dexamethasone) can relieve pain and symptoms in people with mild-to-moderate carpal tunnel syndrome. It aims to provide a non-surgical option for those who haven't improved with other treatments.
Tanta, El GharbiaAges 20–60 - NCT06192615RecruitingPhase 3
Can a sleep medication protect the brain after heart surgery?
This study tests whether a medicine called dexmedetomidine, given after heart surgery, can help prevent confusion and thinking problems in older adults during their intensive care stay. If you are 60 or older and having heart surgery with a heart-lung machine, this trial might be for you.
Los Angeles, CaliforniaAges 60 years+ - NCT06335407RecruitingPhase 1
Testing a new under-the-tongue med for alcohol use and trauma
This study tests a new sublingual (under-the-tongue) medication for people with alcohol use disorder who have also had a traumatic life event. It aims to see if the medication can help reduce drinking and related symptoms.
West Haven, ConnecticutAges 21–65 - NCT06566482RecruitingPhase 4
Medicine for pain after surgery in sleep apnea patients
This trial tests a combination of two medicines (dexmedetomidine and esketamine) given in small doses to help with pain after surgery. It is for people who have sleep apnea or are at risk for it, and who are having chest or belly surgery with a scope.
Beijing, Beijing MunicipalityAges 18–80 - NCT06631534RecruitingPhase 4
Testing dexmedetomidine for kids having heart defect closure
This trial tests adding a sedative medicine called dexmedetomidine to standard anesthesia for children aged 3 to 12 who are having a procedure to close a hole in their heart (atrial septal defect). The goal is to see if it helps them recover more smoothly.
Alexandria, Alexandria GovernorateAges 3–12 - NCT06867302Recruiting
Study on dexmedetomidine for agitation after nose surgery
This trial tests if a medicine called dexmedetomidine can help prevent agitation after nose surgery. You may be eligible if you are a healthy adult having planned nose surgery.
Al Fayyum, Faiyum GovernorateAges 18–50 - NCT06910644Recruiting
Pain relief after mastectomy: dexmedetomidine vs lidocaine
This trial tests whether adding dexmedetomidine or lidocaine to anesthesia during mastectomy helps reduce long-term pain after surgery. It's for women with breast cancer undergoing mastectomy with lymph node removal.
CairoAges 18–75 - NCT06993922Recruiting
Scalp block with added sedative for brain surgery pain
This study tests adding a sedative (dexmedetomidine) to the usual numbing medicine (bupivacaine) for a scalp block before brain surgery. The goal is to see if this combination reduces pain after surgery better than the numbing medicine alone.
CairoAges 18–65 - NCT07050212Recruiting
Sedation study for children having tonsil surgery
This study tests three different medicines to help young children relax before surgery to remove their tonsils and adenoids. It aims to find which medicine works best and is safest for kids ages 2 to 5.
Wuhan, HubeiAges 2–5 - NCT07073846RecruitingPhase 4
Lidocaine and dexmedetomidine for pain after weight-loss surgery
This study tests whether adding two medicines (lidocaine and dexmedetomidine) to your anesthesia during weight-loss surgery can reduce pain, swelling, and stress on the body. It might help you have a smoother recovery.
Mexico City, Mexico CityAges 18–60 - NCT07108764Recruiting
Medicine to prevent confusion after abdominal surgery in seniors
This trial tests giving either lidocaine or dexmedetomidine during abdominal surgery to see if it helps keep the brain healthy and lowers the chance of waking up confused or agitated. It is for older adults having planned abdominal surgery who are otherwise in fairly good health.
Tanta, El-GharbiaAges 65 years+ - NCT07165483Recruiting
Timing of dexmedetomidine for surgery stress response
This trial tests whether giving a single dose of dexmedetomidine (a medicine that helps calm the body's stress response) before surgery can reduce the stress on your heart and blood pressure when a breathing tube is placed. It may help you recover more smoothly.
Tanta, El-GharbiaAges 18–65 - NCT07230197Recruiting
Pregabalin and dexmedetomidine for fibromyalgia pain
This trial tests whether combining two medications, pregabalin and dexmedetomidine, works better than standard treatments for fibromyalgia pain. It may help people with moderate to severe fibromyalgia who haven't found relief from non-drug therapies.
BeijingAges 18 years+
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Common questions
- Are there clinical trials for dexmedetomidine?
- Yes. Clin2 currently lists 191 recruiting dexmedetomidine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dexmedetomidine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dexmedetomidine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.