Clinical trials
Dexmedetomidine clinical trials
Below are recruiting dexmedetomidine clinical trials, each written for real people, not researchers. We’re tracking 178 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07479602RecruitingPhase 4
Medicine via nose for less pain after tonsil surgery in kids
This trial tests whether giving two medicines (dexmedetomidine and esketamine) through the nose can help children ages 3-7 have less pain after their tonsil or adenoid surgery. The goal is to find a better way to manage pain without using strong drugs.
Beijing, Beijing MunicipalityAges 3–7 - NCT05195034Recruiting
Dexmedetomidine to prevent confusion after awake brain surgery
This trial looks at whether a medication called dexmedetomidine can reduce “postoperative delirium,” a temporary period of confusion after awake brain surgery. If you have the type of surgery the study focuses on, this could help your recovery and mental clarity afterward.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07345715Recruiting
Melatonin vs. dexmedetomidine for preventing agitation after tonsil surgery in children
This study tests whether giving children either oral melatonin or a nebulized sedative (dexmedetomidine) before surgery can reduce confusion and restlessness (emergence agitation) when they wake up from anesthesia. It may help children recover more calmly after adenotonsillectomy.
Tanta, El-GharbiaAges 3–7 - NCT07343843Recruiting
Virtual reality vs sedative for anxiety during C-section
This study compares two ways to reduce anxiety and stress during a planned C-section: using a virtual reality headset versus a sedative medicine given through an IV. It aims to see which approach helps mothers feel calmer and supports better outcomes for both mom and baby.
Banhā, BenhaAges 18 years+ - NCT07327905Recruiting
Lidocaine or dexmedetomidine for pain during weight-loss surgery
This trial compares two medicines given through an IV during sleeve gastrectomy (weight-loss surgery) to see which provides better pain control. It may help patients have a smoother recovery with less discomfort.
AlexandriaAges 20–50 - NCT07327931Recruiting
Comparing two PENG block recipes for hip surgery in older adults
This study tests two different types of local numbing medicine (with and without extra additives) for a nerve block called PENG block in older adults having hip surgery. The goal is to find which method controls pain better and reduces the need for strong pain relievers.
PoznanAges 65–100 - NCT07289620Recruiting
Nerve block boosters for kids' leg surgery
This study tests whether adding dexamethasone, dexmedetomidine, or both to a numbing shot (nerve block) provides better pain relief after leg surgery in children. The goal is to find which combination works best to keep your child comfortable with fewer side effects.
PoznanAges 3–12 - NCT03382938Recruiting
Dexmedetomidine injected into C-section wounds
This trial studies whether a specific numbing/comfort medicine (dexmedetomidine) injected into the wound area during a C-section can improve recovery or reduce symptoms after surgery. You may be able to take part if you are a low-risk pregnancy and meet safety requirements.
Athens, OtherAges 18–40 - NCT06859892RecruitingPhase 4
Drug combo study for better sleep after major surgery
This study tests whether a combination of two medicines, dexmedetomidine and esketamine, can help improve sleep problems after major non-heart surgery. You may be eligible if you are having planned surgery lasting at least one hour and will use a pain pump after surgery.
BeijingAges 18 years+ - NCT07276867Recruiting
Spinal Add-On Medicine for Leg Amputation from Sarcoma
This trial tests adding two medicines (dexmedetomidine and fentanyl) versus fentanyl alone to the standard spinal anesthetic for above-knee amputation surgery for lower limb sarcoma. The goal is to see if the combination provides better pain control during and after surgery.
CairoAges 18–60 - NCT07230197Recruiting
Pregabalin and dexmedetomidine for fibromyalgia pain
This trial tests whether combining two medications, pregabalin and dexmedetomidine, works better than standard treatments for fibromyalgia pain. It may help people with moderate to severe fibromyalgia who haven't found relief from non-drug therapies.
BeijingAges 18 years+ - NCT06910644Recruiting
Pain relief after mastectomy: dexmedetomidine vs lidocaine
This trial tests whether adding dexmedetomidine or lidocaine to anesthesia during mastectomy helps reduce long-term pain after surgery. It's for women with breast cancer undergoing mastectomy with lymph node removal.
CairoAges 18–75 - NCT07170267Recruiting
Pain relief study for cesarean section
This study tests whether a nerve block in the lower belly wall (transversalis fascia plane block) or a medication injected into the spinal fluid (intrathecal dexmedetomidine) provides better pain relief for mothers having a planned cesarean section under spinal anesthesia.
Tanta, El-GharbiaAges 18–40 - NCT07165483Recruiting
Timing of dexmedetomidine for surgery stress response
This trial tests whether giving a single dose of dexmedetomidine (a medicine that helps calm the body's stress response) before surgery can reduce the stress on your heart and blood pressure when a breathing tube is placed. It may help you recover more smoothly.
Tanta, El-GharbiaAges 18–65 - NCT07108764Recruiting
Medicine to prevent confusion after abdominal surgery in seniors
This trial tests giving either lidocaine or dexmedetomidine during abdominal surgery to see if it helps keep the brain healthy and lowers the chance of waking up confused or agitated. It is for older adults having planned abdominal surgery who are otherwise in fairly good health.
Tanta, El-GharbiaAges 65 years+ - NCT07078201RecruitingPhase 4
Comparing two pain meds in spinal anesthesia for leg surgery
This study compares two medicines (dexmedetomidine and fentanyl) added to a spinal numbing shot for people having planned leg or knee surgery. The goal is to see which one works better to keep your blood pressure stable, and to make the numbing last while keeping you comfortable.
Port SaidAges 20–60 - NCT07073846RecruitingPhase 4
Lidocaine and dexmedetomidine for pain after weight-loss surgery
This study tests whether adding two medicines (lidocaine and dexmedetomidine) to your anesthesia during weight-loss surgery can reduce pain, swelling, and stress on the body. It might help you have a smoother recovery.
Mexico City, Mexico CityAges 18–60 - NCT07066605Recruiting
Dexmedetomidine for agitation during breathing tube removal
This trial tests whether a sedative called dexmedetomidine can reduce agitation in ICU patients when they are being weaned off a breathing tube. If you experience restlessness or agitation during the weaning process, this medication might help you stay calm.
SohagAges 19 years+ - NCT07050212Recruiting
Sedation study for children having tonsil surgery
This study tests three different medicines to help young children relax before surgery to remove their tonsils and adenoids. It aims to find which medicine works best and is safest for kids ages 2 to 5.
Wuhan, HubeiAges 2–5 - NCT06133712Recruiting
Injection treatment for carpal tunnel pain
This trial tests whether a local injection of three medications (dexmedetomidine, ozone, and dexamethasone) can relieve pain and symptoms in people with mild-to-moderate carpal tunnel syndrome. It aims to provide a non-surgical option for those who haven't improved with other treatments.
Tanta, El GharbiaAges 20–60 - NCT06993922Recruiting
Scalp block with added sedative for brain surgery pain
This study tests adding a sedative (dexmedetomidine) to the usual numbing medicine (bupivacaine) for a scalp block before brain surgery. The goal is to see if this combination reduces pain after surgery better than the numbing medicine alone.
CairoAges 18–65 - NCT06082856Recruiting
Dexmedetomidine for heart stability during outpatient surgery
This trial tests whether a drug called dexmedetomidine, given during general anesthesia, helps keep your heart rate and blood pressure stable during outpatient surgery. It may be an option if you are having a minor surgery and are not on certain heart medications.
NîmesAges 18 years+ - NCT05640453RecruitingPhase 4
Testing pregabalin or dexmedetomidine for post-surgery delirium
This study compares two medicines—pregabalin and dexmedetomidine—to treat confusion (called delirium) after heart bypass surgery. It aims to see which drug works better to reduce delirium symptoms in older adults after coronary artery bypass surgery.
Tanta, El-Gharbia GovernorateAges 65 years+ - NCT06867302Recruiting
Study on dexmedetomidine for agitation after nose surgery
This trial tests if a medicine called dexmedetomidine can help prevent agitation after nose surgery. You may be eligible if you are a healthy adult having planned nose surgery.
Al Fayyum, Faiyum GovernorateAges 18–50
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Common questions
- Are there clinical trials for dexmedetomidine?
- Yes. Clin2 currently lists 178 recruiting dexmedetomidine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dexmedetomidine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dexmedetomidine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.